Medical Clinical Research

Sana Akhtar

Email:***********@*******.***

Mob: 009**-*********

Total Experience: 9 Years

Summary

Working as a Toxicologist Pharmacy college Drug and poison information centre from November 2011 to till date.

Worked as a Toxicologist in security forces clinic(Toxicology) Drugs testing lab & clinical research under Ministry of Interior, Govt. of Saudi Arabia since 21st may 2004 to 20 April 2011..

worked as a Research Fellow in University Collage of Medical science(ucms)Delhi university from August 2003 to april 2004.

worked as a Lecturer In Department of Toxicology in Al-Hafeez Collage from June 2001 to December 2002.

Work History: :

At present working as a Toxicologist in DIC & PIC mNinistry of higher education Saudi Arab from 2011 to at present, Using Micromedex.

Worked as a Toxicologist in the Toxicology Lab 0f Ministry of Interior in Saudi Arabia from May 2004 to 24 april 2011 .I established Drug Testing Lab performing drug screening, sample validity testing and confirming Non Negative specimens. using techniques following College Of American Pathology and SAMHSA guidelines and keeping proper Chain of Custody of each specimen from recieving to reporting of the results.

worked as a Research fellow on the UGC approved project entitled Phototoxic potential of the test Drugs SPARFLOXACIN in swiss albino mice In UCMS,Delhi

Project Summary:Phototoxic potential of the test Drugs SPARFLOXACIN in swiss albino mice.

Photobiology Principle:photobiology is the study of the effect of optical radition (UVA and UVB)in living system.

Experimental Design:swiss mice were detained from experimental animal faculty .in the weight range og 25-30 gm and 4-5 weeks old at receipt. At the beginning of the body weight was taken .

Duration:Animal were kept for two weeks acclimation period so that they are approximetly 40 days old.the animal were observed for 5 days after an hour and 24 hour past irradiation period.

Experimental procedure:total of 4 days

20 swiss female mice were divided into four groups of mice and they were kept in polypropylene cages with paddy husk and bedding.

Animal in each cages were identified by furmarking and then weight.

After 24 hr of dosing the animal hair were clipped with the help of electric cliper and hair removing cream.

UV-A irradiation:

The animal will be irradiated for 3 hours starting 1 hour after each daily drugs dose.

Observation:the mice to be observed an hour and 24 hour lost irradiation to note changes.skin and ears will be assessed for severity of erythema and edema scoring will be the follwing scale by visual inspection.

0No reaction

1Very slight reaction

2Well defined reaction

3Moderate to severe erythema

4Severe erythema to eschar formation

On day 5 all mice were scarified and gross pathological finding were noted.

worked as a Research fellow on the UGC approved project entitled “Genetic Profile of Wilms Tumor and associated Nephrogenic rests” under the supervision of Prof. KIRAN MISHRA, Deptt. of Pathology, UCMS & GTB Hospital from from August 2003 to april 2004.

EXPERIMENTAL SKILLS

Biochemical Estimation: Protein, Glucose, Cholesterol, Glutathione, Bilirubin, Bilivirdin, Lipid Peroxidation

Enzymatic Estimation: Activity of GST, SGOT, SGPT, Catalase, Na & K ATPase activity.

Dose Test: LD50 calculation.

Cosmetic Toxicology Testing : Control v/s Treated Swiss albino mice.

- Hydroquinone estimation in cosmetics.

- Nitrocellulose stability determination.

- Irritation Potential estimation in murine skin.

- Estimation of glutathione, catalase, and LPO from induced skin.

Ecotoxicology studies : Estimation of Dissolved oxygen in water sample.

Estimation of BOD, COD.

Estimation of total Dissolved solid(TDS)

Estimation of total Suspended solid(TSS)

Neurobehavioral Toxicology:

Study of CatalepsyTesting Study of morris water maze

Study of Tranquilizers using Cook’s Pole Climbing Appratus

Study of Tranquilizers using Video path Analyzer.

Technique Using : Biochemistry Analyzer, Haematology Analyzer. HPLC, Extraction,Toxicology

Drugs Analyzer.ELISA

Major responsibilities:

Design and monitoring experimental programs

Data evaluation and preparing risk assessments

Good working knowledge in urine toxicology for drugs detection in urine,using HPLC, VIVA drugs analyzer,

Sampleing,chain of custody, etc

EDUCATIONAL ATTAINMENT

Master in Toxicology from jamia hamdard university new delhi in 2001.

Bachelor of science in chemistry in 1998,india

Computer qualification: Diploma in computer application from new delhi(Operating Systems: Windows 98/2000/xp, Unix, DOS.)

License: Society of Toxicology India.

Saudi Medical Counsil

Instrument Handling:,HPLC,VIVA DRUGS ANALYZER,RA50,HEAMATOLOGY ANALYSER,ELISA

Working Knowledge

Animal dosing I.V and orally collection,, Routing histopathological Technique.necropsy,staining,immune staining,preparation of buffer,mounting,section cutting,embedding,Dog,rabbit,albino mice handling.

Seminar Attended :

Drugs and abuse on 3 june 2007 jeddah,k.sa

Drugs and Abuse Symposium In Jeddah 2008

New Trends in Toxicology sypmposium Jeddah 2011.

Drugs and abuse workshop,Jeddah 2007

References:

1.Abdul Razak Kasab (Director)

Security Forces Clinic

Ministry of Interior

Al-Jouf,k.s.a

2.Dr.Kiran Mishra

University Collage of Medical Science

Delhi University,India

3.Dr.Haider Ali Khan

Toxicology Deapartment

Jamia Hamdard University,India

Personal Details

Father’s Name: Akhtar Hussain

Languages Known :English,Arbic,urdu

Iqama no: 231-***-****

Job no: 74602

Place : Sakaka,aljouf

Date :

Sana Akhtar

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