RASHI ASTHANA

** ******* ******, *******, ** L*P 3M9 647-***-**** adct68@r.postjobfree.com EDUCATION

University of Toronto St. George, Toronto, ON

Doctor of Philosophy (Ph.D.) Pharmaceutical Sciences Jan 2018 – present Collaborative Program in Biomedical Toxicology

Thesis: “Drug transporter dysregulation in an in vitro and an ex vivo model of preeclampsia.”

Supervisors: Dr. Micheline Piquette-Miller

University of Guelph, Guelph, ON

Master of Science (M.Sc.) Clinical Studies Sept 2015- Aug 2017 Thesis: “Evaluation of a simulated pneumoperitoneum environment on cancer cell growth using an in vitro model with positive pressure carbon dioxide insufflation and canine transitional cell carcinoma”

Dissertation published at the Atrium on the University of Guelph website. Supervisors: Dr. Michelle L Oblak and Dr. Ameet Singh York University, Toronto, ON

Bachelor of Science (B.Sc.) Specialized Honors Sept 2008- Dec 2013 Kinesiology and Health Sciences

Member of the Dean’s Honour Roll June 2014

Honours Thesis: Dr. Gary Sweeney Lab “Effects of Adiponectin and high fat diet on unfolded protein response (UPR), endoplasmic reticulum (ER) stress, autophagy and apoptosis in HepG2 Hepatocytes in vitro”

TEACHING ASSISTANTSHIPS

University of Toronto St. George, Toronto, ON

PHM241H Lab - Topics in Pharmaceutical Quality & Clinical Laboratory Medicine Sept – Dec 2019 Department of Pharmaceutical Sciences

Dr. David Dubins and Dr. Ray Reilly

AWARDS

University of Toronto, Center for Pharmaceutical Oncology (CPO) Scholarship [4,000] Sept 2019-2020 University of Toronto, Mary Gertrude I'Anson Scholarship [$4,000] September 2019 University of Toronto, Ontario Graduate Scholarship [$15,000] Sept 2019-Aug 2020 University of Toronto, Pharmaceutical Sciences Graduate September 2018 Student Association Fellowship (GSEF) [$5,000]

University of Guelph, Queen Elizabeth II Graduate Scholarship Sept 2017-Aug 2018 in Science and Technology (declined) [$15,000]

University of Guelph, Lena Cooke Memorial Award [$450] April 2016 University of Guelph, Graduate Tuition Scholarship [$16,000] Sept 2015 – Aug 2017 University of Guelph, OVC GRATS Award [$16,000] Sep 2015 – Aug 2017 York University, Tuition Grant [$800] January 2012 York University, Undergraduate Entrance Award [$600] July 2008 PUBLICATIONS

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Yen Ting Shen, Rashi Asthana, Casper Peeters, Christine J Allen, Carlo De Angelis, Micheline Piquette-Miller.

"Potential Limitations of Bioluminescent Xenograft Mouse Models: A Systematic Review". Journal of Pharmacy & Pharmaceutical Sciences. Manuscript submitted December 17, 2019. Eliza R. McColl*, Rashi Asthana*, Mary F. Paine, and Micheline Piquette-Miller. “Editorial: The age of omics- driven precision medicine.” Clinical Pharmacology & Therapeutics. DOI: https://doi.org/10.1002/cpt.1532

*Eliza and Rashi are co-first authors

Rashi Asthana, Liying Zhang, Bo Angela Wan, Daniela Gallo-Hershberg, Angie Giotis, Mark Pasetka, Jenna Van Draanen, Shannon Goodall, Patrick L Diaz, Leah Drost, Edward Chow, Carlo DeAngelis. “Pain descriptors of Taxane Acute Pain Syndrome (TAPS) in breast cancer patients- a prospective clinical study.” Supportive Care in Cancer. May 17, 2019. https://doi.org/10.1007/s00520-019-04845-7 Rashi Asthana, Shannon Goodall, Jenny Lau, Camilla Zimmermann, Patrick Diaz, Bo Angela Wan, Edward Chow, Carlo DeAngelis. “Framing of the opioid problem and its implications in the management of cancer pain in Canada: A critical appraisal.” Perspective in Current Oncology. Vol 26, No 3 (June 2019). DOI: http://dx.doi.org/10.3747/co.26.4517

Rashi Asthana, Bo Angela Wan, Patrick Diaz, George Charames, Carlo DeAngelis, Akanksha Kulshreshtha, Caitlin Yee, Leah Drost, Leila Malek, Edward Chow and Joav Merrick. “Editorial: Taxane-associated Acute Pain Syndrome: Myths or facts” Journal of Pain Management. August 21, 2018. Volume 11, Issue 2. https://www.novapublishers.com/catalog/product_info.php?products_id=64302 Caitlin Yee, Bo Angela Wan, Linda Probyn, Vithusha Ganesh, Leah Drost, Akanksha Kulshreshtha, Rashi Asthana, Edward Chow, Elizabeth Barnes. “Tibial metastasis as a presenting symptom of endometrial adenocarcinoma: A case report” Journal of Pain Management. August 21, 2018. Volume 11, Issue 2. https://www.novapublishers.com/catalog/product_info.php?products_id=64302 Patrick L Diaz, Anthony Furfari, Bo Angela Wan, Henry Lam, George Charames, Leah Drost, Angelo Fefekos, Shannon Ohearn, Alexia Blake, Rashi Asthana, Edward Chow, Carlo DeAngelis. “Predictive biomarkers of chemotherapy-induced peripheral neuropathy: A review” Biomarkers in Medicine. July 25, 2018. https://doi.org/10.2217/bmm-2017-0427

Caitlin Yee, Katie Wang, Rashi Asthana, Leah Drost, Henry Lam, Justin Lee, Danny Vesprini, Eric Leung, Carlo DeAngelis, Edward Chow. “Radiation-induced skin toxicity in breast cancer patients: A systematic review of randomized trials.” Clinical Breast Cancer. July 4, 2018. pii: S1526-8209 (18) 30114-9. https://doi.org/10.1016/j.clbc.2018.06.015

Rashi Asthana, Michelle Oblak, Ameet Singh, Anthony J. Mutsaers. “In vitro evaluation of a simulated pneumoperitoneum environment using carbon dioxide on canine transitional cell carcinoma cell lines.” Veterinary Surgery 2018. Apr;47(3):412-420. https://doi.org/10.1111/vsu.12778 PRESENTATIONS

The Center for Pharmaceutical oncology (CPO) 2019 Research Symposium April 16, 2019 Toronto, Ontario

Poster Presentation

“Docetaxel induced NF-kB signaling pathway and its potential implications in Taxane Acute Pain Syndrome (TAPS).”

Canadian Association of Pharmacy in Oncology (CaPhO) May 3-6, 2018 Ottawa-Gatineau, QC

Poster Presentation

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“Pain Descriptors of Taxane Acute Pain Syndrome (TAPS) in breast cancer patients

– a prospective study.”

American College of Veterinary Surgeons (ACVS) Oct 12-14, 2017 Indianapolis, Indiana USA

Poster Presentation

“In vitro evaluation of a simulated pneumoperitoneum environment on canine transitional cell carcinoma viability, proliferation and migration.” Rapid Response Radiotherapy Program (RRRP)

And Bone Metastases Site Group Clinic (BMC) Nov 7, 2017 Toronto, Ontario

Oral Presentation

“Clinical study to identify predictive biomarkers of susceptibility to Taxane Associated Pain Syndrome (TAPS) in early breast cancer patients receiving adjuvant taxane-based chemotherapy.”

Institute of Comparative Cancer Investigation (ICCI) May 25, 2017 University of Guelph, Ontario Veterinary College, Guelph ON Poster Presentation

“In vitro evaluation of a positive pressure CO2 environment on canine transitional cell carcinoma.”

Princess Margaret Personalizing Cancer Medicine Feb 6, 2017 Toronto, ON

Poster Presentation

“In vitro evaluation of laparoscopy on canine transitional cell carcinoma: a translational model”

Graduate Student Research Symposium Nov 16, 2016

University of Guelph, Ontario Veterinary College, Guelph ON Oral Presentation

“In vitro evaluation of a simulated capnoperitoneum on proliferation of canine transitional cell carcinoma”

Global One Health Day Nov 3, 2016

University of Guelph, Guelph ON

Poster Presentation

“In vitro evaluation of CO2 laparoscopy on canine transitional cell carcinoma: a translational model”

Veterinary Cancer Society (VCS) Oct 20-22, 2016

Orlando, Florida USA

Poster Presentation

“In vitro evaluation of a simulated capnoperitoneum on proliferation of canine transitional cell carcinoma”

RESEARCH EMPLOYMENT EXPERIENCE

Sunnybrook Odette Cancer Center, Toronto ON

Clinical Research Assistant Aug – Dec 2017

Dr. Edward Chow and Dr. Carlo De Angelis

Conduct literature reviews

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Collaborate with faculty, statisticians, and students to write and publish scientific papers

Editing and preparing manuscripts for publications: editorials, reports, systematic reviews, and presentations

Attend project meetings, seminars, and other conferences Other duties as assigned by supervisors

University of Toronto St. George, Toronto ON

Summer Research Assistant May – Aug 2013

Dr. Peter Backx

Learned about transgenic mice with alterations in cardiac calcium ion channel function and how that initiates and contributes to cardiovascular disease. Trained mice (swimming and running)

Analyzed experimental data for graduate students

Observed surgeries and experiments on mice

Tagged mice ears and clipped for genotyping

MEMBERSHIPS

University of Toronto St. George, Toronto, ON

American Association of Pharmaceutical Scientists (AAPS) July 2018 – 2020 Graduate Student Membership AAPS Student Chapter University of Toronto University of Toronto St. George, Toronto, ON

Canadian Association of Pharmacy in Oncology (CaPhO) March 2018 – 2019 EXTRA-CURRICULAR ACTIVITIES

Graduate Research in Progress (GRIP) at Leslie Dan Faculty of Pharmacy University of Toronto, Toronto ON

Co-Chair Nov 2018 – June 2019

Organize the event with other members of the team, including faculty Pharmaceutical Sciences Graduate Student Association (PSGSA) University of Toronto, Toronto ON

Treasurer Sept 2018- Aug 2019

Manage finances for the PSGSA, manage financial statements Apply for department and university-wide funding, advise on fundraising strategies

Report finances to the PSGSA- banking, bookkeeping, and record keeping Advise on financial implications and operational plans American Association of Pharmaceutical Scientists (AAPS) University of Toronto, Toronto ON

Outreach Coordinator Sept 2018- Aug 2019

Build strategic relationships with the community

Fundraise, conduct outreach activities

Create annual outreach plans – recruit, train and utilize volunteers Develop outreach materials

Assist in grant research and writing

[References available upon request]

[Updated: April 5, 2020]

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