Fariba Fathi

Research Scientist; ade6gi@r.postjobfree.com;

*** ***** ******* * *******, WI; 608-***-**** & 608-***-**** Summary:

• Forward-thinking scientist with a strong background in analytical chemistry and biochemistry leading to develop methods to identify important biomarkers in biological samples to support the diagnosis and treatment of diseases.

• Excellent team player and strong builder of prolific collaborations in different aspects of basic and applied research to long-lasting research projects accomplishing > 4 SOPs, > 30 peer-reviewed journal publications, > 10 poster presentation, 3 grant proposals, and awards.

• Proven ability to meet tight deadlines by working in a fast-paced work environment leading to successful completion of more than 20 collaborations.

• Established experience of theoretical and practical basics of the variety analytical technology leading to mentor and teach undergraduate students.

Technical skills:

• Over 12 years of hands-on experience in method development and validation including preparation and analysis of small molecules in biological fluids and tissues (Blood, Serum, CSF, different tissues, urine and cell line) and for analytical instruments (HPLC/MS and NMR).

• Experience operating NMR, U/HPLC, LC/MS, QTRAP LC-MS/MS System UV and FTIR, familiar with detection techniques( CAD, ELSD, IC).

• Experience operating a wide variety of analytical methodologies including Karl Fischer, FPLC, pH testing, atomic absorption, and more.

• Understanding of the drug development process and experience in drug discovery.

• Working knowledge of statistical methods and data analysis methods and data interpretation using various programming languages (MATLAB, OCTAVE). Advanced experience with Microsoft office.

• Understanding with GMP and GLP requirements.

Education:

• Ph.D. in Chemistry Sharif University of Technology Sep 2008– Oct 2012

• MSc. in Chemistry Sharif University of Technology Sep 2006 – Oct 2008

• BSc. Chemistry Kharazmin University Feb 2003 - Jul 2006 Professional Experience:

Research associate University of Wisconsin; Madison -WI Oct 2018 – Now 40 hours/week

• Demonstrated the feasibility of using NMR to analysis metabolites within synaptosomal fractions to compare the metabolic composition synaptosomes from a wild-type rat with that from a newly generated genetic rat model.

• Developed the effective analytical method for metabolites s’ extraction in biological samples; preparing more than 2000 samples. Protected our lab reputation and improve collaborators satisfaction by establishing new technologies for metabolite profiling and Lipidomics.

• Identified and quantified of small molecule in liver, small intestine, and red blood cell by NMR and U/HPLC to investigate on liver vitamin A accumulation in rats.

• Performed metabolite profiling by NMR and LC/MS in whole blood and urine samples for understanding the effect of diet and exercise in diabetes and Alzheimer’s disease.

• Acquired over $50,000 in doing project for our industrial collaborator to support our lab. Postdoc fellow University of Wisconsin; Madison -WI Oct 2015 – Sep2018

• Managed and successfully completed above concurrent projects under strict timeline to meet program reporting requirements.

• Designed and established a metabolic profiling in plasma samples to recognize the role of gut microbiota in cardiovascular diseases by NMR and LC/MS in rat models.

• Screened potentially metabolites in liver tissues to discover the important biomarkers in diet plans by analytical instrument.

• Prepared plan and successful finished for Metabolic profiling of CSF samples with the goal of identifying biomarkers related with the risk of developing anxiety disorders

• Prepared & implemented metabolomics to realize the mechanism responsible for the effect of two different drugs in the treatment of Leishmaniasis.

• Analyzed the changes in the metabolite in urine samples from two different strains of mice Teaching instructor Farhangeyan University Oct 2012-Sep 2015 Teaching Courses: General chemistry 1, 2 and 3; Physical chemistry 1, 2; Physical chemistry lab 1, 2; Molecular Spectroscopy, Analytical Chemistry 1, 2 Research assistant Sharif University of Technology, Tehran, Iran Sep2010-Oct 2012

• Provided scientific leadership and designed in metabolomics area in our lab.

• Designed and equipped the lab for performing metabolomics for studying Parkinson, Multiple Sclerosis, Celiac and Crohn’s disease using NMR spectroscopy.

• Created a new regression model with great prediction outcomes between NMR data and serum levels of zinc and selenium which were measured by atomic absorption.

• Supervised students on laboratory techniques such as sample preparation, centrifugation, and spectroscopic techniques.

Teaching assistant Sharif University of Technology Tehran, Iran Sep2008-Sep 2010 Teaching assistance of Molecular spectroscopy and

Physical chemistry 1 and 2

Awards &Honors:

US permanent resident, Awarded “National Interest Waiver” Green Card by U.S. Citizenship and Immigration based on “exceptional ability” (2017).

Ranked 700th in national entrance exam of the state universities among 100,000 participants (2003).

Outstanding Science Award, Sharif University of Technology, 2012

Teaching Effectiveness, Sharif University of Technology, 2013

Invited as a reviewer for the American Journal of Internal Medicine; SEJ Gastroenterology and Live journal.

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