Assistant Sales
Resume:
David Joseph Garmene
************@*****.***
P.O. Box 55476, Indianapolis, IN 46205
SUMMARY OF EXPERIENCE
Successful medicinal/organic chemist professional with a strong background in drug discovery research emphasizing structural design processes, organic synthesis methodology and/or optimization processes seeks a Associate Product R&D Import Compliance Coordinator position in the pharmaceutical industry with a focus on ensuring import/export transaction compliances, inventory management and manage internal/external customer relationships.
EDUCATION
Master of Business Administration December 2010
Butler University, Indianapolis, Indiana
Concentration: Finance
GPA: 3.32/4.0
• Due diligence case study on Ducati, sport motorcycle manufacturer, emphasizing product-line mix issues as a result of declining sales, declining Net Marketing Contribution (NMC) issues as a result poor marketing strategies, and their failure to capture customer’s interests and demands for their “superbike” flagship product.
• Equipment replacement study utilizing cost-benefit analysis on Eli Lilly and Company’s purification systems utilizing income statements and cash flows to estimate IRR and NPV.
• Managed a virtual $1M trading account for 4 weeks emphasizing executions of derivatives. Generated ~28% or ~$280,000 ROI utilizing technical/fundamental analysis and entering/exiting trade strategies on futures, options and equities.
Master of Science in Organic Chemistry December 2001
Purdue University, West Lafayette, Indiana
Research Advisor: Professor Mark A. Lipton
Bachelor of Science in Chemistry
December 1997
Ball State University, Muncie, Indiana
ACS Certified
PROFESSIONAL EXPERIENCE
Associate Consultant Organic Chemist
March 2007–June 2010
Eli Lilly and Company, Indianapolis, IN
Discovery Chemistry Research and Technology
• Used structural activity relationships (SAR) studies to develop potential therapeutic drug candidate(s) through multi-step synthesis independently
• Create optimized synthetic route(s) to improve synthetic yield(s)
• Obtained medicinal chemistry experience in neuroscience targeting ion channel
Associate Organic Chemist
August 2003–February 2007
Eli Lilly and Company, Indianapolis, IN
Discovery Chemistry Research and Technology
• Managed and utilized a Biotage microwave reactor to gain synthetic advantage on maximizing yields performing difficult chemistry
• Managed sample submissions for testing from various projects
• Used centrifugal thin-layer chromatography to purify <300 mgs of final products to maximize recover and purity.
• Gained medicinal chemistry experience in neuroscience targeting cell-surface receptors and enzymes
Assistant Scientist II January 2002–July 2003
Pfizer Inc., Groton, CT
• Developed and utilized hydrogenation techniques using Parr Shaker instruments to perform various olefin reductions applications
• Acquired reverse phase high pressure liquid chromatography skills using analytical and prep-scale Shimadzu HPLC for purification of milligram/gram quantities of intermediates and final products
• Acquired knowledge in scientific computer applications and proficiency in documentation including ISIS Reaction Browser, SciFinder, Beilstein, ChemDrawPro, and ISIS Base
• Obtained medicinal chemistry experience in inflammation targeting cell surface receptors
Supervisor
August 2001–December 2001
Purdue University, West Lafayette, IN
• Supervised 10 teaching assistants and 9 organic laboratory sections
• Handled unresolved matters between teaching assistants and students
Graduate Research Assistant
August 1998–December 2001
Purdue University, West Lafayette, IN
• Completed thesis entitled “The Development of a New Pseudopeptide: Polyureidopeptides”
• Gained knowledge in amide coupling in making amino acid derivatives
PATENTS AND PUBLICATIONS
Freeman-Cook, K. D., Reiter, L. A., Noe, M. C., Antipas, A. S., Danely, D. E., Datta, K., …Garmene, D.J.
(2007). Potent, selective spiropyrrolidine pyrimidinetrione inhibitors of MMP-13. Bioorganic & medicinal chemistry letters, 17(23), 6529-34.
Amegadzie, A. K., Dao, Y., Gardiner, K. M., Garmene, D. J., Green, S. J., Hembre, E. J., … Lu, J. (2007).
Preparation of thieno[2,3-c]pyridine derivatives as MCH receptor antagonists. PCT Int. Appl., WO 200-***-****.
Arnold, M. B., Dao, Y., Gardiner, K. M., Garmene, D. J., Green, S. J., Hembre, E. J., & Lu, J. (2007).
Thienopyridines as melanin-concentrating hormone receptor antagonists, their preparation, pharmaceutical compositions, and use in therapy. PCT Int. Appl. WO 200-***-****.
Gardiner, K. M., Garmene, D. J., Hembre, E. J., Brunavs, M., & Szekeres, H. J. (2008). Thiazolopyridinone
derivatives as MCH receptor antagonists and their preparation, pharmaceutical compositions and use in the treatment of obesity. PCT Int. Appl. WO 200-***-****
Patent Number: 8049013; Title: 5-[4-(azetidin-3-yloxy)-phenyl]-2-phenyl-5H-thiazolo[5,4-C]
Patent Number: 8101764; Title: MCH receptor antagonists
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