Project Management Chemistry

Panduranga Adulla Reddy, Ph.D

** ******** ***** ****, *******, MA, 02081, USA

Phone: 617-***-**** (Cell); 508-***-**** (Home) email: ************@*****.***

15+ years of successful track record in drug discovery (Medicinal Chemistry as focus) in diverse therapeutic areas in pharmaceutical/biotech industry

Accomplished Scientist/Leader/Manager. Full scope of Lead discovery, Lead optimization to development stage. Repeatedly attracted, retained top talent and built loyal, high performing teams. Combined with integrity and authentic leadership to create an environment where people accept with respect. Effectively communicated vision, mission and strategy to diverse multi disciplinary teams/groups at geographically different locations. Achieved results in fast-paced, changing, and challenging environment. Put in place clear strategy (operational plans, explicitly stated goals and objectives) & Budget planning.

Ph. D. Synthetic Organic Chemistry.

Post doctoral research in synthesis and conformational studies on peptides at CUNY, New York, followed by Structure Based Design and synthesis of peptide and peptidomimetic ligand inhibitors for CD4 protein at Thomas Jefferson University.

Patents [37, issued/published (27), filed (10)] and papers [36, published (31) & in press/in preparation (5)]

Professional Experience: Industrial

Merck Research Labs: Senior Principal Scientist: Nov.2009-Present

Leading the multiple projects [lead discovery and lead optimization stages (Oncology)]

One program (Kinase inhibitor) to be nominated (scheduled for Feb-2011) for preclinical evaluation

Schering Plough Research Institute: Senior Principal Scientist: Nov.2002-Nov.2009 [Acquired by Merck)

Leading the multiple projects [lead discovery and lead optimization stages (Oncology, infectious, and inflammation disease areas)].Two programs (Oncology) in clinical trials (Phase I/II) and multiple programs at various levels

One program (Inflammation/diabetes) evaluated in preclinical

Serono Research Institute: Principal Scientist & Group Leader: 1995- Oct.2002. [Acquired by Merck KGA]

Built chemistry group (20+ chemists) and closely working/interacting with interdisciplinary teams in US & across Atlantic. Focus on the therapeutic areas of woman health and inflammation. One program entered in Phase I (GnRH antagonists, endometriosis and endometrial cancer) and three programs [woman health (FSH agonists) and inflammation/COPD (EP2 antagonists] evaluated in preclinical studies

Professional Experience: Academic: Teaching and Research

Thomas Jefferson University: 1993-1994

Post doctoral Visiting Scientist: Molecular modeling and design of peptides and peptidomimetic inhibitors

City University of New York: 1992-1993

Post doctoral Visiting Scientist: Biophysical studies on structure of Peptide ligands & GPCR Protein transmembrane fragments

Osmania University (India): 1985-1991

Assistant Professor: In addition to teaching to M.S. (Organic Chemistry), guided four students for their Ph.D. degree

Leadership Style:

Empower people to do their jobs responsibly and ensure that they do their work motivated & enthusiastically, by taking ownership. Giving the credit to deserved.

Delegate the work to people to work on their own with team spirit, so that they assume ownership. Encourages teamwork and believes that team success is success of all. Recognition and pride associated with success is important.

Liaison/Project management: Working with multi disciplinary groups/Selecting CRO’s, Collaborative Research Partners [external (academic and industrial research partners)].

Experience interpreting, coordinating in vitro and in vivo biological data and coordination with diverse groups.

Coordinate with the DMPK & in vivo biology groups to optimize the timelines for effective results

Project Management Training:

Serono Corporate Management (2000)

Mass Biotech Council (2004)

Patents & Involvement with patents/intellectual property:

37 patents (issued, published (27) or filed (10)]. Worked closely with team patent attorneys (Legal, I.P.) in identifying the scope, writing drafts and associated all the way to the filing.

Papers/presentations published:

31 published and 5 in press/manuscript preparation

Computational tools/methods

Modest experience with computational chemistry (Tripos, Schrodinger, Accelrys, ACD, Pymol etc) and chemo informatics but comfortable in getting the work done with computational chemist and chemo informatics persons to the needs of chemistry/biology in lead identification and optimization.

Example of a Creative Solution to a Scientific OR Business Problem

When there was management pressure on results/timelines and too few people, set the priorities, motivate people with opportunity and reward. Outsourced the needs of medicinal chemistry and coordinated all tasks to get the results in desired time frame. Nominated for CEO award for “Scientific Leadership” at Serono

Factors Important to Ensure Job Satisfaction

Scientific challenge. Team environment and Successful achievement of goals.

Unique, Applicable Characteristics that Candidate Brings to Position

Leadership through honesty/transparency/harmony and lead by example

All aspects drug discovery: Target identification through development [lead generation, lead optimization (medicinal chemistry, DMPK, in vivo Biology & Safety-- all the way to development).]

PATENTS, PRESENTATIONS AND PAPERS:

Patents:

1, Deng, Yongqi; Sun, Binyuan; Zeng, Hongbo; Richards, Matthew; Shipps, Gerald W., Jr.; Cheng, Cliff C.; Zhao, Yinyan; McRiner, Andrew; Meng, Zhaoyang; Nan, Yang; Patel, Mehul F.; Wrona, Iwona E.; Reddy, Panduranga Adulla; Eklov, Brian M.; Tang, Shuyi; Liu, Duan; Mandal, Amit K.; Zhao, Lianyun; Siddiqui, M. Arshad. Pyrazolo [1, 5-a] pyrimidine derivatives as m-TOR inhibitors. PCT Int. Appl. (2010), 726pp. CODEN: PIXXD2 WO 201******* A1 20101014 AN 2010:1284389 CAPLUS

2, Ciavarri, Jeffrey P.; Reddy, Panduranga A.; Siddiqui, M. Arshad; Zhao, Lianyun. Preparation of imidazopyrazines as therapeutic protein and checkpoint kinase inhibitors. PCT Int. Appl. (2010), 100pp. CODEN: PIXXD2 WO 201******* A2 20100805 CAN 153:260377 AN 2010:969339 CAPLUS

3, Mansoor, Umar Faruk; Reddy, Panduranga Adulla; Siddiqui, M. Arshad. Preparation of urea derivatives as antibacterial agents for treatment of diseases mediated by LpxC. PCT Int. Appl. (2010), 75pp. CODEN: PIXXD2 WO 201******* A1 20100211 CAN 152:214852 AN 2010:178458 CAPLUS

4, Reddy, Panduranga Adulla P.; Mansoor, Umar Faruk; Siddiqui, M. Arshad. Preparation of heterocyclic compounds as LpxC inhibitors for use as antibacterial agents. PCT Int. Appl. (2009), 84pp. CODEN: PIXXD2 WO 200-***-**** A1 20091230 CAN 152:97336 AN 2009:1615453 CAPLUS

5, Ciavarri, Jeffrey P.; Reddy, Panduranga Adulla P.; Siddiqui, M. Arshad; Zhao, Lianyun. Preparation of imidazopyrazines as therapeutic protein and checkpoint kinase inhibitors. U.S. Pat. Appl. Pub. (2009), 63pp. Cont.-in-part of U.S. Ser. No. 758,243. CODEN: USXXCO US 200-***-**** A1 20090709 CAN 151:124041 AN 2009:828538 CAPLUS

6, Reddy, Panduranga Adulla P.; Wong, Tzu T.; Zhao, Lianyun; Tang, Shuyi; Labroli, Marc A.; Guzi, Timothy J.; Siddiqui, M. Arshad. Preparation of thiazole derivatives as protein kinase inhibitors. PCT Int. Appl. (2009), 141pp. CODEN: PIXXD2 WO 200-***-**** A1 20090507 CAN 150:515156 AN 2009:553415 CAPLUS

7, Labroli, Marc A.; Poker, Cory Seth; Wong, Tzu T.; Reddy, Panduranga Adulla P.; Guzi, Timothy J.; Siddiqui, M. Arshad. Preparation of thiazole diamides as protein kinase inhibitors. PCT Int. Appl. (2009), 105pp. CODEN: PIXXD2 WO 200-***-**** A1 20090507 CAN 150:515155 AN 2009:548552 CAPLUS

8, Reddy, Panduranga Adulla P.; Zhao, Lianyun; Tadikonda, Praveen K.; Wong, Tzu Tshin; Tang, Shuyi; Torres, Luis E.; Cauble, David F., Jr.; Guzi, Timothy J.; Siddiqui, M. Arshad. Heterocyclic amide compounds as protein kinase inhibitors and their preparation, pharmaceutical compositions and use in the treatment of diseases. PCT Int. Appl. (2009), 245pp. CODEN: PIXXD2 WO 200-***-**** A2 20090129 CAN 150:191533 AN 2009:115374 CAPLUS

9, Reddy, Panduranga Adulla P.; Siddiqui, Arshad M.; Tadikonda, Praveen K.; Mansoor, Umar Faruk; Shipps, Gerald W., Jr.; Belanger, David B.; Zhao, Lianyun. Preparation of imidazo[1,2-a]pyridines, imidazo[1,2-a]pyrazines, imidazo[1,2-c]pyrimidines, and imidazo[1,2-d]triazines as JNK and ERK kinase inhibitors. PCT Int. Appl. (2008), 362pp. CODEN: PIXXD2 WO 200-***-**** A2 20080710 CAN 149:153112 AN 2008:832833 CAPLUS

10, Belanger, David B.; Siddiqui, M. Arshad; Curran, Patrick J.; Hamann, Blake; Zhao, Lianyun; Reddy, Panduranga Adulla P.; Tadikonda, Praveen K.; Shipps, Gerald W., Jr.; Mansoor, Umar Faruk. Preparation of pyridines and pyrimidines as JNK and ERK kinase inhibitors. PCT Int. Appl. (2008), 243pp. CODEN: PIXXD2 WO 200-***-**** A2 20080710 CAN 149:153074 AN 2008:829945 CAPLUS

11, Belanger, David B.; Siddiqui, M. Arshad; Guzi, Timothy J.; Curran, Patrick J.; Tadikonda, Praveen K.; Hamann, Blake; Reddy, Panduranga Adulla P.; Zhao, Lianyun. Preparation of imidazopyrazines as protein kinase inhibitors. PCT Int. Appl. (2008), 138 pp. CODEN: PIXXD2 WO 200-***-**** A2 20080515 CAN 148:561939 AN 2008:583780 CAPLUS

12, Shipps, Gerald W., Jr.; Cheng, Cliff C.; Huang, Xiaohua; Fischmann, Thierry O.; Duca, Jose S.; Richards, Matthew; Zeng, Hongbo; Sun, Binyuan; Reddy, Panduranga A.; Wong, Tzu T.; Tadikonda, Praveen K.; Siddiqui, M. Arshad; Labroli, Marc M.; Poker, Cory; Guzi, Timothy J. Anilinopiperazine derivatives and methods of use thereof and their preparation. PCT Int. Appl. (2008), 330 pp. CODEN: PIXXD2 WO 200-***-**** A1 20080508 CAN 148:538303 AN 2008:552346 CAPLUS

13, Shipps, Gerald W., Jr.; Cheng, Cliff C.; Huang, Xiaohua; Fischmann, Thierry O.; Duca, Jose S.; Richards, Matthew; Zeng, Hongbo; Sun, Binyuan; Reddy, Panduranga A.; Zhao, Lianyun; Tang, Shuyi; Wong, Tzu T.; Tadikonda, Praveen K.; Torres, Luis E.; Siddiqui, M. Arshad; Dwyer, Michael P.; Keertikar, Kartik M.; Guzi, Timothy J. 2-Aminothiazole-4-carboxylic amides as protein kinase inhibitors and their preparation, pharmaceutical compositions and use in the treatment of diseases. PCT Int. Appl. (2008), 274pp. CODEN: PIXXD2 WO 200-***-**** A1 20080508 CAN 148:538302 AN 2008:551551 CAPLUS

14, Mansoor, Umar Faruk; Reddy, Panduranga Adulla P.; Siddiqui, M. Arshad. Preparation of methylhydantoin derivatives for use as antimicrobial agents. PCT Int. Appl. (2008), 97 pp. CODEN: PIXXD2 WO 200-***-**** A1 20080306 CAN 148:308346 AN 2008:285076 CAPLUS

15, Zhao, Lianyun; Reddy, Panduranga Adulla P.; Shih, Neng-Yang; Paruch, Kamil; Guzi, Timothy J.; Siddiqui, M. Arshad. Imidazopyrazines as protein kinase inhibitors and their preparation, pharmaceutical compositions and use in the treatment of kinase-mediated diseases. PCT Int. Appl. (2007), 145pp. CODEN: PIXXD2 WO 200-***-**** A1 20071221 CAN 148:79068 AN 2007:1454778 CAPLUS

16, Siddiqui, M. Arshad; Mansoor, Umar Faruk; Reddy, Panduranga Adulla P.; Madison, Vincent S. Preparation of tartaric acid functional compounds for the treatment of disorders mediated by MMPs, aggrecanase, ADMP, LpxC, ADAMs, TACE and TNF- U.S. Pat. Appl. Publ. (2007), 556pp. Cont.-in-part of U.S. Ser. No. 291,595. CODEN: USXXCO US 200-***-**** A1 20070719 CAN 147:166197 AN 2007:793702 CAPLUS

17, Siddiqui, M. Arshad; Mansoor, Umar Faruk; Reddy, Panduranga A.; Madison, Vincent S. 2,3-Dihydroxybutane-1,4-diamide compounds for the treatment of inflammatory disorders and microbial diseases and their preparation. PCT Int. Appl. (2007), 119pp. CODEN: PIXXD2 WO 200-***-**** A1 20070607 CAN 147:72471 AN 2007:618723 CAPLUS

18, Zhao, Lianyun; Curran, Patrick J.; Belanger, David B.; Hamann, Blake; Reddy, Panduranga A.; Paruch, Kamil; Guzi, Timothy. J.; Dwyer, Michael P.; Siddiqui, M. Arshad; Tadikonda, Praveen K. Preparation of imidazopyrazines as protein kinase inhibitors. PCT Int. Appl. (2007), 276 pp. CODEN: PIXXD2 WO 200-***-**** A2 20070524 CAN 147:9950 AN 2007:567437 CAPLUS

19, Guzi, Timothy J.; Paruch, Kamil; Dwyer, Michael P.; Parry, David A.; Zhao, Lianyun; Curran, Patrick J.; Belanger, David B.; Hamann, Blake; Reddy, Panduranga Adulla P.; Siddiqui, M. Arshad; Tadikonda, Praveen K. Imidazopyrazine compounds and their methods for inhibiting protein kinases, preparation, pharmaceutical compositions and use in the treatment of protein kinase-associated diseases. U.S. Pat. Appl. Publ. (2007), 346pp. CODEN: USXXCO US 200-***-**** A1 20070510 CAN 146:501082 AN 2007:507532 CAPLUS

20, Guzi, Timothy J.; Paruch, Kamil; Dwyer, Michael P.; Siddiqui, M. Arshad; Reddy, Panduranga Adulla P.; Belanger, David B.; Hamann, Blake; Curran, Patrick J. Preparation of novel pyrazolopyrimidines as cyclin dependent kinase inhibitors. U.S. Pat. Appl. Publ. (2007), 60 pp., Cont.-in-part of U.S. Ser. No. 244,776. CODEN: USXXCO US 200-***-**** A1 20070329 CAN 146:380001 AN 2007:359119 CAPLUS

21, Siddiqui, M. Arshad; Manor, Muar Faro; Reddy, Panduranga A.; Madison, Vincent S. Preparation of tartaric acid functional compounds for the treatment of inflammatory disorders mediated by MMPs, aggrecanase, ADMP, LpxC, ADAMs, TACE and TNF- U.S. Pat. Appl. Publ. (2006), 523 pp., Cont.-in-part of U.S. Ser. No. 142,601. CODEN: USXXCO US 200-***-**** A1 20060810 CAN 145:230531 AN 2006:796760 CAPLUS

22, Guzi, Timothy J.; Paruch, Kamil; Dwyer, Michael P.; Zhao, Lianyun; Curran, Patrick J.; Belanger, David B.; Hamann, Blake; Reddy, Panduranga A.; Siddiqui, M. Arshad. Preparation of novel imidazopyrazines as cyclin dependent kinase inhibitors. U.S. Pat. Appl. Publ. (2006), 161 pp., Cont.-in-part of U.S. Ser. No. 47,524. CODEN: USXXCO US 200-***-**** A1 20060518 CAN 144:488677 AN 2006:463553 CAPLUS

23, Araldi, Gian Luca; Karra, Srinivasa; Reddy, Adulla P.; Liao, Yihua; Zhao, Zhong. Preparation of thiophenes and furans as prostaglandin, in particular prostaglandin EP2, agonists. PCT Int. Appl. (2004), 109 pp. CODEN: PIXXD2 WO 200-***-**** A2 20040212 CAN 140:163700 AN 2004:120667 CAPLUS

24, Araldi, Gian Luca; Reddy, Adulla P.; Zhao, Zhong; Mckenna, Sean D.; Bao, Bagna. Preparation of -lactams as prostaglandin EP4 agonists and uses thereof. PCT Int. Appl. (2003), 137 pp. CODEN: PIXXD2 WO 200-***-**** A2 20031218 CAN 140:42024 AN 2003:991301 CAPLUS

25, Araldi, Gian Luca; Liao, Yihua; Reddy, Adulla P.; Zhao, Zhong. Preparation of pyrazolidinones as ligands of the prostaglandin EP2 and/or EP4 receptors. PCT Int. Appl. (2003), 106 pp. CODEN: PIXXD2 WO 200-***-**** A1 20030501 CAN 138:353975 AN 2003:334902 CAPLUS

26, Shroff, Hitesh; Reddy, Adulla P.; El Tayar, Nabil; Brugger, Nadia; Jorand-Lebrun, Catherine. Preparation of pyrazole compounds for treatment of infertility. PCT Int. Appl. (2001), 90 pp. CODEN: PIXXD2 WO 200******* A2 20011122 CAN 135:371991 AN 2001:850926 CAPLUS

27, El Tayer, Nabil; Reddy, Adulla; Buckler, David; Magar, Sharad. Preparation of carbazoles, isoquinolines, indoles, and related compounds as follicle stimulating hormone mimetics for the treatment of infertility. PCT Int. Appl. (2000), 62 pp. CODEN: PIXXD2 WO 200******* A2 20000217 CAN 132:151680 AN 2000:117043 CAPLUS

Patents filed (to be published):

***** Ten Patents filed

List of papers/presentations published:

1, Zhaoyang Meng, Bheemashankar A. Kulkarni, Angela D. Kerekes, Johannes Voigt, Amit K. Mandal, Sara J. Esposite, David B. Belanger, Panduranga Adulla Reddy, Andrea D. Basso, Kimberly Gray, Seema Tevar, Jennifer Jones, Elizabeth Smith, Ronald Doll M. Arshad Siddiqui. Biosteric approach to the discovery of imidazo[1,2-a] pyrazines as potent Aurora Kinase inhibitors., Bioorganic & Medicinal Chemistry Letters (20108), published on line

2, Zhaoyang Meng, Bheemashankar A. Kulkarni, Angela D. Kerekes, Johannes Voigt, Amit K. Mandal, Sara J. Esposite, David B. Belanger, Panduranga Adulla Reddy, Andrea D. Basso, Kimberly Gray, Seema Tevar, Jennifer Jones, Elizabeth Smith, M. Arshad Siddiqui, Ronald Doll, From Isothiazole to Thiophene and Thiazole: A BioisostericApproach to the Discovery of Potent Imidazo[1,2-a]pyrazines as Aurora Kinase Inhibitors., Abstracts of Papers, 240th ACS National Meeting, Boston, MA, United States, August 22-26, 2010 (2010),

3, Siddiqui, M. Arshad; Reddy, Panduranga A.. Small Molecule JNK (c-Jun N-Terminal Kinase) Inhibitors. Journal of Medicinal Chemistry (2010), 53(8), 3005-3012. CODEN: JMCMAR ISSN:0022-2623. CAN 152:372532 AN 2010:176474 CAPLUS

4, Xiao, Yufang; Araldi, Gian Luca; Zhao, Zhong; Reddy, Adulla; Karra, Srinivasa; Brugger, Nadia; Fischer, David; Palmer, Elizabeth; Bao, Bagna; Mckenna, Sean D. Synthesis and evaluation of a -lactam as a highly selective EP2 and EP4 receptor agonist. Bioorganic & Medicinal Chemistry Letters (2008), 18(2), 821-824. CODEN: BMCLE8 ISSN:0960-894X. CAN 148:379408 AN 2008:85194 CAPLUS

5, Zhao, Zhong; Araldi, Gian Luca; Xiao, Yufang; Reddy, Adulla P.; Liao, Yihua; Karra, Srinivasa; Brugger, Nadia; Fischer, David; Palmer, Elizabeth. Synthesis and evaluation of novel pyrazolidinone analogs of PGE2 as EP2 and EP4 receptors agonists. Bioorganic & Medicinal Chemistry Letters (2007), 17(23), 6572-6575. CODEN: BMCLE8 ISSN: 0960-894X. CAN 148:121623 AN 2007:1279259 CAPLUS

6, Jorand-Lebrun, Catherine; Brondyk, Bill; Lin, Jing; Magar, Sharad; Murray, Robert; Reddy, Adulla; Shroff, Hitesh; Wands, Greg; Weiser, Weishui; Xu, Qihong; McKenna, Sean; Brugger, Nadia. Identification, synthesis, and biological evaluation of novel pyrazoles as low molecular weight luteinizing hormone receptor agonists. Bioorganic & Medicinal Chemistry Letters (2007), 17(7), 2080-2085. CODEN: BMCLE8 ISSN: 0960-894X. CAN 146:501311 AN 2007:267455 CAPLUS

7, Zhao, Zhong; Bao, Bagna; Brugger, Nadia; Fischer, David; Giachetti, Claudio; Golzio, Lucia; Karra, Srinivasa; Marinelli, Paolo; McKenna, Sean; Palmer, Elizabeth; Reddy, Adulla; Xiao, Yufang; Araldi, Gian Luca. Discovery of potent prostaglandin EP2 and EP4 receptors agonists that inhibit bronchomuscle constriction in guinea pigs. Abstracts of Papers, 228th ACS National Meeting, Philadelphia, PA, United States, August 22-26, 2004 (2004), MEDI-056. CODEN: 69FTZ8 AN 2004:657920 CAPLUS

8, Gautam Agnihotri, Margaret Porter Scott, Moulay Hicham Alaoui-Ismaili, Faruk Mansoor, Denise Murphy, Adulla P. R. Reddy, Gerald Shipps, Arshad Siddiqui, Praveen Tadikonda, Charles Whitehurst, and Huw Nash. Identification of Potent Inhibitors of c-Jun N-terminal Kinase – 1 using Ultra High-Throughput Affinity-Based Screening

Poster presentation at the 12th Symposium on Second Messengers and Phospho-proteins (SMP-2004), Montreal, QC. (Aug 3 - Aug 7, 2004).

9, Zhao, Zhong; Bao, Bagna; Brugger, Nadia; Fischer, David; Giachetti, Claudio; Golzio, Lucia; Karra, Srinivasa; Marinelli, Paolo; McKenna, Sean; Palmer, Elizabeth; Reddy, Adulla; Xiao, Yufang; Araldi, Gian Luca. Discovery of potent prostaglandin EP2 and EP4 receptors agonists that inhibit bronchomuscle constriction in guinea pigs. Abstracts of Papers, ACS National Medicinal Chemistry symposium, Madison, Wisconsin, United States, June 27-1st July, 2004 (2004),

10, Zhang Zhao, Adulla P.R.Reddy, Yihua Liao, Srinivas Karra, Araldi Gian Luca*

Preparation of pyrazole compounds for treatment of infertility

XVIIIth International Symposium on Medicinal chemistry, Copenhagen, Sweden, August , 2004

11, El Tayar, Nabil; Reddy, Adulla; Liao, Yihua; Magar, Sharad; Murray, Robert; Kozack, Richard; Weiser, Weishui; Nabioullin, Roustem; Rosenthal, Judy; Buckler, David; Cheng, Shirley; Liu, Jane; McKenna, Sean; Jiang, Xuliang; Evans, David; Tepper, Mark; Goutopoulos, Andreas. Small Molecule FSH-mimetics. Abstracts of Papers, 224th ACS National Meeting, Boston, MA, United States, August 18-22, 2002 (2002), MEDI-355. CODEN: 69CZPZ AN 2002:618206 CAPLUS

12, Goutopoulos, Andreas; Reddy, Adulla; Liao, Yihua; Magar, Sharad; Murray, Robert; Weiser, Weishui; Nabioullin, Roustem; Rosenthal, Judy; Buckler, David; Cheng, Shirley; Liu, Jane; McKenna, Sean; Jiang, Xiuliang; Evans, David; Tepper, Mark; El Tayar, Nabil. Proline and pipecolic acid-based agonists of the follicle-stimulating hormone receptor. Abstracts of Papers, 226th ACS National Meeting, New York, NY, United States, September 7-11, 2003 (2003), MEDI-365. CODEN: 69EKY9 AN 2003:634973 CAPLUS

13, Zhao, Zhong; Bao, Bagna; Brugger, Nadia; Fischer, David; Giachetti, Claudio; Golzio, Lucia; Karra, Srinivasa; Marinelli, Paolo; McKenna, Sean; Palmer, Elizabeth; Reddy, Adulla; Xiao, Yufang; Araldi, Gian Luca. Discovery of potent prostaglandin EP2 and EP4 receptors agonists that inhibit bronchomuscle constriction in guinea pigs. Abstracts of Papers, 228th ACS National Meeting, Philadelphia, PA, United States, August 22-26, 2004 (2004), MEDI-056. CODEN: 69FTZ8 AN 2004:657920 CAPLUS

14, Friedman, Thea M.; Reddy, Adulla P.; Wassell, Richard; Jameson, Bradford A.; Korngold, Robert. Identification of a human CD4-CDR3-like surface involved in CD4+ T cell function. Journal of Biological Chemistry (1996), 271(37), 226**-*****. CODEN: JBCHA3 ISSN: 0021-9258. CAN 125:219068 AN 1996:572224 CAPLUS

15, Reddy, K. Hemender; Reddy, A. Panduranga; Veeranagaiah, V. Synthesis of alkyl/aryl substituted pyrazolo[1,5-a]pyrimidines. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry (1993), 32B (5), 586-9. CODEN: IJSBDB ISSN: 0376-4699. CAN 121:9352 AN 1994:409352 CAPLUS

16, Rao, V Sudhakar; Rao, S Sreedhar Prasad; Reddy, A. Panduranga; Veeranagaiah, V. Studies on the formation of 2-methyl-imidazo [4, 5-g] benzothiazoles from 6,7-diamino-2-methylbenzothiazole. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry (1993), 32B (3), 322-7. CODEN: IJSBDB ISSN: 0376-4699. CAN 119:28053 AN 1993:428053 CAPLUS

17, Rao, M. Hanumantha; Reddy, A. Pandu Ranga; Veeranagaiah, V. Synthesis of 1H-1,5-benzodiazepin-2(3H)-ones from 5(4H)-isoxazolone, a heterocyclic bifunctional C-3 synthon. Synthesis (1992), (5), 446-8. CODEN: SYNTBF ISSN: 0039-7881. CAN 117:69839 AN 1992:469839 CAPLUS

18, Reddy, K. Hemender; Reddy, A. Panduranga; Veeranagaiah, V. Versatile synthesis of 6-alkyl(aryl)-1H-pyrazolo[3,4-d]pyrimidin-4[5H]-ones. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry (1992), 31B (3), 163-6. CODEN: IJSBDB ISSN:0376-4699. CAN 116:174107 AN 1992:174107 CAPLUS

19, Rao, M. Hanmantha; Reddy, A. Pandu Ranga; Veeranagaiah, V. A convenient approach to the synthesis of quinoxalines from isoxazolones and 1, 2-diaminobenzenes. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry (1992), 31B(2), 88-91. CODEN: IJSBDB ISSN: 0376-4699. CAN 116:128865 AN 1992:128865 CAPLUS

20, Rao, M. Hanmantha; Reddy, A. Pandu Ranga; Veeranagaiah, V. A new synthetic approach towards the synthesis of 2-(3-aryl-2H-1,4-benzothiazin-2-yl)-3-aryl-2H-1,4-benzothiazines. Synthetic Communications (1991), 21(17), 1715-20. CODEN: SYNCAV ISSN: 0039-7911. CAN 115:232157 AN 1991:632157 CAPLUS

21, Reddy, A. Panduranga; Reddy, C. P. R. Kasi. An efficient method for the synthesis of N-(p-aminobenzoyl) amino acids. Organic Preparations and Procedures International (1990), 22(1), 117-19. CODEN: OPPIAK ISSN: 0030-4948. CAN 113:24482 AN 1990:424482 CAPLUS

22, Rao, S. Krishan; Reddy, A. Pandu Ranga; Veeranagaiah, V. Synthesis of imidazo-, pyrazino- and diazepinoquinoxalines from quinoxaline-5,6-diamine and ketones. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry (1989), 28B (11), 918-22. CODEN: IJSBDB ISSN: 0376-4699. CAN 112:118768 AN 1990:118768 CAPLUS

23, Reddy, A. Panduranga; Veeranagaiah, V. Studies on the stability of 2,2,4-trialkyl-2,3-dihydro-1H-[1,4]diazepino[2,3-f]quinolines. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry (1989), 28B (3), 272-3. CODEN: IJSBDB ISSN: 0376-4699. CAN 111:134110 AN 1989:534110 CAPLUS

24, Rao, S. Kishan; Reddy, A. Pandu Ranga; Veeranagaiah, V. Synthesis of 2-substituted 1H-imidazo [4, 5-f] quinoxalines. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry (1988), 27B (10), 960-1. CODEN: IJSBDB ISSN: 0376-4699. CAN 111:97184 AN 1989:497184 CAPLUS

25, Reddy, B. Saida; Reddy, A. Panduranga; Veeranagaiah, V. One-pot synthesis of 3-aryl-2,3-dihydro-2-thioxobenzofuro[3,2-d]pyrimidin-4(1H)-ones. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry (1988), 27B(12), 1131-3. CODEN: IJSBDB ISSN: 0376-4699. CAN 111:77951 AN 1989:477951 CAPLUS

26, Reddy, A. Ram; Reddy, A. Pandu Ranga. Exciplex formation in 2-propanol solutions of imidazo [4, 5-f] quinolines. Journal of Photochemistry (1987), 38 255-61. CODEN: JPCMAE ISSN: 0047-2670. CAN 108:55348 AN 1988:55348 CAPLUS

27, Reddy, A. Pandu Ranga; Veeranagaiah, V. Condensation of quinoline-5, 6-diamine with ketones. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry (1986), 25B(5), 527-9. CODEN: IJSBDB ISSN: 0376-4699. CAN 106:67273 AN 1987:67273 CAPLUS

28, Reddy, A Pandu Ranga; Veeranagaiah, V. Studies on the formation of imidazo [4,5-f]quinolines from quinoline-5,6-diamine and aromatic aldehydes. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry (1985), 24B (4), 372-6. CODEN: IJSBDB ISSN: 0376-4699. CAN 104:109533 AN 1986:109533 CAPLUS

29, Reddy, A. Pandu Ranga; Veeranagaiah, V.; Ratnam, C. V. Synthesis and autoxidation of 1,3-dialkyl-2-arylbenzimidazolines. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry (1985), 24B (4), 367-71. CODEN: IJSBDB ISSN: 0376-4699. CAN 104:109532 AN 1986:109532 CAPLUS

30, Reddy, A. Pandu Ranga; Veeranagaiah, V. A facile synthesis of 2-substituted imidazo [4, 5-f] quinolines. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry (1984), 23B (7), 673-4. CODEN: IJSBDB ISSN: 0376-4699. CAN 101:211049 AN 1984:611049 CAPLUS

31, Reddy, A. Pandu Ranga; Veeranagaiah, V. Condensation of quinoline-5,6-diamine with benzaldehyde. Current Science (1982), 51(1), 39. CODEN: CUSCAM ISSN: 0011-3891. CAN 98:34546 AN 1983:34546 CAPLUS

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