Content Medical

RIDDHI DALVI

**C McGreevey way, Boston, MA *****

*****.******@*****.***, 617-***-****

EDUCATION

Northeastern University, Boston, MA, Apr 2012

Master of Science in Biomedical Sciences

Relevant course work: Concepts of Pharmaceutical Sciences, Human Physiology and Pathophysiology, Biochemistry, Molecular Cell Biology, Pharmaceutical Sciences Laboratory, Experimental Design and Biostatistics, Advanced Drug Delivery Systems, Drug Discovery and Evaluation.

Mumbai University

Bachelor of Pharmacy, Mumbai, India, Jul 2010

Relevant course work: Laboratory and Practical Experience in Pharmacology, Pharmacognosy, Pharmaceutics, Biotechnology, Cosmetic Science, Pharmaceutical Analysis, Medicinal Chemistry

Activities: Member of Student Cultural Committee, Active Participation in AIDS Awareness Drive

LABORATORY SKILLS

Cell Culture, Fluorescence Microscopy, Transfection, Cytotoxicity assays, Protein Assays, Dialysis, ELISA, Column (Size exclusion) Chromatography, Nanoparticles- Micelles preparation, HPLC, In vitro assays, Western Blot, SDS- PAGE, Affinity Chromatography, Immunohistochemistry, RNA Extraction, Animal handling.

WORK EXPERIENCE

Nemucore Medical Innovations, Inc, Worcester, MA, Feb 2012 - April 2012

Intern

• Conducted mammalian cell culture maintain cell lines of SKOV3, SKOV3 TR, and PANC 1

• Prepared nanoemulsions and analyze their cytotoxicity with MTT cytotoxicity assay

• Prepared SOP in accordance with the protocols of the company

• Maintained inventory of laboratory requirements and chemicals

Centre for Pharmaceutical Biotechnology and Nanomedicines Laboratory, Boston, MA, Jan 2011 – Jan 2012

Research Assistant

Northeastern University

• Conducted HPLC to find the concentrations of the given samples

• Prepared and analyze cancer targeting micelles

• Analyze DNA Polymer complexes for size and zeta potential

• Performed ELISA to find the concentration of the antibody in the given samples

• Conducted cell culture and maintain cancer cell lines (B-16, MCF-7, HELA) for various experiments

• Performed drug extraction from given blood sample and analyze it- for vivo animal studies

• Performed protein assay (Bradford Assay) to determine the transferrin and antibody content in samples

Sehat Pharmaceuticals, Gujarat, India, May 2009 - June 2009

Trainee

• Maintained the chemical storage under company specified rules

• Analyzed the automated manufacturing process of the liquid formulation

• Tested the efficiency of packaging in the in process packaging of liquid formulations

• Assisted in manual labeling of the packaged products

• Analyzed the quality and the drug content in the in-process and the final liquid formulation by methods mentioned in Indian Pharmacopoeia

PROJECTS/SEMINARS

DNA and PEI-PE complexes – for enhancing the DNA gene delivery, Boston, MA, Mar 2011 – Jul 2011

• Prepared complexes of DNA and novel polymer PEI-PE

• Analyzed the size and zeta potential of the complexes

• Prepare cell samples for cell interaction analysis in FACS

Transferrin and 2C5 Antibody tagged Paclitaxel loaded Micelles, Boston, MA

• Prepared micelles and tag them with Transferrin and 2C5 antibody to target them to cancer cells

• Analyzed the micelles drug content with HPLC and performing the cytotoxicity assay on MCF-7 cell lines

• Performed Protein assay for transferrin content and ELISA for 2C5 antibody content

PUBLICATION

• Rupa R. Sawant, Shravan Kumar Sriraman, Gemma Navarro, Swati Biswas, Riddhi A. Dalvi, Vladimir P. Torchilin. “Polyethyleneimine-lipid conjugate-based pH-sensitive micellar carrier for gene delivery” Biomaterials 2012 May;33(15):3942-51. Epub 2012 Feb 25.

• NMI-2100 Nemucore Medical Innovation project poster for Center for Cancer Nanotechnology and Excellence annual visit, March 21, 2012, Northeastern University

COMPUTER KNOWLEDGE

• Windows 95/98/2000/XP/Vista/2007, Microsoft Office Word, PowerPoint, Excel.

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