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Location:
Hamden, CT
Posted:
September 08, 2011

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Resume:

Yuhua (Hugh) Zhang, Ph.D.

Home Address: *** ***** **** **, ******, CT 06518

Tel: 504-***-**** (cell)

Email: *****@*****.***

Work Status: Green Card (don’t need sponsor)

I. EMPLOYMENT

*/*009 – 7/2011 Research Chemist in Analytical Chemistry

MW LABS, Inc., Savannah, GA

Develop analytical methods to test active ingredients (Ibuprofen, Camphor, Menthol, Wintergreen Oil, Allantoin, Salicylic Acid, Nicotinamide, Arginine, Benzalkonium Chloride, Benzyl Alcohol et al) in cosmetic products and determine purity of raw materials, operate and maintain laboratory equipments including Varian 500-MS, Varian CP-3800 GC/FID, Bruker ALPHA FT-IR.

10/2007 – 6/2009 Postdoc Research Associate in Organic Chemistry

Department of Chemistry, Washington University in St. Louis, St. Louis, MO

Synthesis of bicyclic imidines and isothiazoleurea compounds; Investigation of their asymmetric catalysis in kinetic resolution and organic reactions;

Supervisor: Professor Vladimir B. Birman

12/2003 –10/2007 Postdoc Research Associate in Organic Chemistry

Department of Chemistry, Tulane University, New Orleans, LA

Transition metal-catalyzed and organo-catalyzed cross dehydrogenative coupling reactions; Au(III)-catalyzed tandem synthesis of N-vinyl indole;

Supervisor: Professor Chao-Jun Li

8/2001 – 12/2003 Assistant Professor in Organic/organometallic Chemistry

Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, China

Synthesis and characterization of novel organometallic clusters containing Cobalt and Nickel.

II. EDUCATION

1996 – 2001 Ph.D. in Organic/organometallic Chemistry

Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, China

Synthesis, reactivity and catalytic application of novel organometallic compounds, especially on enantiomeric separation of chiral metal cluster and organometallic macromolecule synthesis by metal-exchange reactions.

Supervisor: Professor Yuan-Qi Yin

1992 – 1996 B.S. in Chemistry

Shandong Normal University, China

III. QUALIFICATIONS AND SKILLS

Strong experiences in Analytical, Organic and Organometallic Chemistry:

1. Strong experience in method development with LC/MS/MS and GC/FID.

2. Strong operation, calibration, maintenance, and trouble shooting skills in LC/MS/MS, GC/MS, GC/FID, HPLC/UV, FT-IR, Viscometer, pH meter, and other equipments in chemical laboratory.

3. Multiple-step organic synthesis, retrosynthetic analysis, new reaction methodology, and identification of unknown compounds by various spectroscopic methods (1D/2D NMR, MS, IR, UV and etc.), identification of reaction mechanism, organic synthesis and separation skills.

4. Experience at Kilogram-scale reactions.

5. Low-temperature and high-pressure techniques.

6. Manipulation of air/water sensitive compounds by using Schlenk line techniques and glove box.

7. Strong oral and written communication skills.

IV. AWARDS AND AFFILIATIONS

1. The Outstanding Award honored by the Chinese Academy of Sciences’ President in 2002.

2. The Top-class Peng Yingang Scholarship, Chinese Academy of Sciences in 2001.

3. The Outstanding Graduate of the Year, Shandong Normal University in 1996.

4. Member of the American Chemical Society since 2004.

V. REPRESENTATIVE PUBLICATIONS

1. Yuhua Zhang, Vladimir B. Birman, Effects of methyl substituents on the activity and enantioselectivity of homobenzotetramisole-based catalysts in the kinetic resolution of alcohols, Adv. Synth. Catal., 2009, 351, 2525.

2. Woo-jin, Yoo, Camille A, Correia, Yuhua Zhang, Chao-Jun Li, Oxidative alkylation of cyclic benzyl ethers with malonates and ketones, Synlett, 2009, 138.

3. Yuhua Zhang, Jianqing Feng, Chao-Jun Li, Palladium-catalyzed methylation of aryl C-H bond by using peroxides, J. Am. Chem. Soc., 2008, 130(10), 2900.

4. Yuhua Zhang, Chao-Jun Li, Highly efficient direct alkylation of activated methylene by simple alkanes, Eur. J. Org. Chem., 2007, 4654.

5. Carolyn S. Reid, Yuhua Zhang and Chao-Jun Li, Fluorous-Tag: An enabling isolation technique for indium-mediated allylations reactions in water, Org. & Biomol. Chem., 2007, 5(22), 3589.

6. Yuhua Zhang, James P. Donahue, Chao-Jun Li, Highly efficient double hydroaminition of ortho-alkynylaniline with terminal alkynes leading 1-alkene indoles, Org. Lett., 2007, 9, 627.

7. Yuhua Zhang, Chao-Jun Li, Highly efficient cross-dehydrogenative-coupling between ethers and active methylene compounds, Angew. Chem. Int. Ed., 2006, 45, 1949.

8. Yuhua Zhang, Chao-Jun Li, DDQ-meidated direct cross-dehydrogenative-coupling (CDC) between benzyl ethers and single ketones, J. Am. Chem. Soc., 2006, 128, 4242.

9. Xiao-Fan Yang, Mingwen Wang, Yuhua Zhang, Chao-Jun Li, 2.4-Diaryltetrahydropyran formation by the Prins cyclization and its application towards the synthesis of Epicalyxin F and Calyxin I, SynLett, 2005, 12, 1912.

10. Yuhua Zhang, Chao-Jun Li, Microwave-assisted direct addition of cycloethers to alkynes, Tetrahedron Lett., 2004, 45, 7581.

11. Quan-Yi Zhao, Yu-Hua Zhang, Bin Hu, Wei-Qiang Zhang, Bao-Hua Zhu, Yuan-Qi Yin, Chun-Gu Xia, Asymmetric inducing synthesis of optically active tetrahedral cluster containing SMCoW core, Chin. J. Chem., 2004, 22(7), 757.

12. Quan-Yi Zhao, Wei-Qiang Zhang, Yu-Hua Zhang, Bin Hu, Yuan-Qi Yin, Chun-Gu Xia, Synthesis of optically active tetrahedral clusters through ester exchange catalyzed by lipase, Organomet., 2004, 23(4), 817.

13. Yu-Hua Zhang, Pu Liu, Chun-Gu Xia, Bin Hu, Yuan-Qi Yin, Study of metal exchange reactions in cobalt containing clusters, J. Organomet. Chem., 2003, 676(/1-2), 55.

14. Zhang Yu-Hua, Li Qing-Shan, Xia Chun-Gu, Yin Yuan-Qi, Zhou Zhong-Yuan, Chen Xin-Zi, Synthesis and characterization of new linked clusters, Chem. J. Chin. Univ., 2002, 23(8), 1515.

15. Zhang Yu-Hua, Hu Bin, Xia Chun-Gu, Chen Zhi, Yin Yuan-Qi, Synthesis and characterization of dipropargyl esters, Chin. J. Syn. Chem., 2002, 10(4), 335.

16. Zhang Yu-Hua, Yuan Jian-Chao, Yin Yuan-Qi, Zhou Zhong-Yuan, Albert S. C. Chan, Synthesis and reactions of chiral clusters containing an SRuCoMo core, New J. Chem., 2001, 25, 939.

17. Yu-Hua Zhang, Jian-Chao Yuan, Wen-Jian Lao, Yuan-Qi Yin, Zi-Xiang Huang and Jiang-Jin Wu, Synthesis, characterization and reactions of cluster complexes containing SeRuCoM (M = Mo or W) core and a functionally substituted cyclopentadienyl ligand, J. Organomet. Chem., 2001, 628(1), 123.

18. Yu-Hua Zhang, Wen-Jian Lao, Yue-Qi Liu, Yuan-Qi Yin, Jiang-Jin Wu and Zi-Xiang Huang, Reactions of dipropargyl manolate, terephthalate with Co2(CO)8, Mo2Cp2(CO)4 and RuCo2(CO)11 give the di or tetranuclear clusters. The crystal structure of [CH2(CO2CH2C2H- )2][Co2(CO)6]2 and [p-(HC2CH2OCO)C6H4(CO2CH2C2H- )][Co2(CO)6], Polyhedron, 2001, 20(9-10), 1107.

19. Yu-Hua Zhang, Jian-Chao Yuan, Yuan-Qi Yin, Zhong-Yuan Zhou and Albert S. C. Chan. Preparation and reactions of tetrahedrane-type clusters containing a SCoFeM (M = Mo or W) core. The single crystal X-ray structure of the cluster ( 3-S)CoFeMo(CO)8[ 5-C5H4C(O)CH2CH2CO2Me], Polyhedron, 2001, 20(15-16), 1859.

20. Yu-Hua Zhang, Chun-Gu Xia and Yuan-Qi Yin, Attempts to resolute metal clusters with chiral framework by optically active hydrazides, Inorg. Chim. Acta, 2001, 325(1-2), 198.

21. Yu-Hua Zhang, Xue-Nian Chen, Jie Zhang, Yuan-Qi Yin*, Jiang-Jin Wu and Zi-Xiang Huang, “Reactions of dipropargyl oxalate with Co2(CO)8, RuCo2(CO)11 and crystal structure of (COOCH2C2H- )2[Co2(CO)6]2”, J. Chem. Res(S), 2000, 8, 378-378.

22. Zhang Yu-Hua, Wu Shu-Lin, Li Qing-Shan, Yin Yuan-Qi, Asymmetric synthesis of mixed metal clusters induced by phase-transfer catalysts, J. Mol. Cat. (China), 2001, 15(2), 134.

23. Zhang Yu-Hua, Xu Yi, Chen Min-Dong, Zhu Xin-Yi, Chen Zhi, Yin Yuan-Qi, Resolution of chiral metal clusters catalyzed by lipase, J. Mol. Cat. (China), 2000, 14(2), 151.

24. Jie Zhang, Yu-Hua Zhang, Xue-Nian Chen, Er-Run Ding, and Yuan-Qi Yin, Regioselective metal exchange reactions in linked clusters, Organomet., 2000, 19, 5032.

VI. REFERENCES

References will be provided upon request.



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