Mike-Resume
Resume:
J. Michael Padron
* ********** *****, ********, ** 08619
Email: *******@***.***
OBJECTIVE:
To obtain a position where I can fully utilize my diverse background in Neuroscience, Pharmacology, Drug Metabolism/Pharmacokinetics, Safety Assessment/Toxicology, and Laboratory Animal Science & Welfare
EXPERIENCE:
1/08-Present
Sanofi-Aventis, Bridgewater, NJ
Temporary position contracted through Artech Information Systems, Cedar Knolls, NJ
Animal Research & Welfare Department
IACUC COMPLIANCE ADMINISTRATOR
Work for a large pharmaceutical company managing all aspects of their regional Institutional Animal Care & Use Committee (IACUC). Responsible for assuring all files and documents are in compliance with animal welfare laws and regulations (USDA, OLAW, PHS, AAALAC, etc). Administer protocol and related submissions throughout the review process. Plan and coordinate committee meetings with departments across all sites. Generate reports, meeting minutes, regulatory submissions, and presentations as needed. Schedule and track all required inspections (facility program review, post-approval compliance monitoring, etc) and subsequent reports. Oversee and provide training of all new IACUC members, investigators, and animal users. Involved in the development, testing and implementation of a new electronic web-based animal use protocol writing, submission and review program.
1/07-1/08
Zoo Games (formerly Destination Software), Sicklerville, NJ
PROJECT MANAGER
Worked for a small video game publishing company that develops, distributes and markets video games for console and hand-held platforms. Supervised the development of titles (projects) from initial contracting to final approval and distribution. Oversaw communication between licensors and developers. Managed maintenance of timelines for game development schedule. Directed creation of company website and update as needed. Generated business reports as needed.
9/00-10/06
Palatin Technologies, Inc., Cranbury, NJ
Biological & Preclinical Research Department
ASSOCIATE SCIENTIST (9/02 – 10/06)
SENIOR RESEARCH ASSOCIATE (9/00 – 8/02)
Worked for a small biotechnology company where I performed drug discovery research and preclinical development on novel peptides and small molecules for the treatment of several diseases/disorders, such as erectile/sexual dysfunction, obesity/cachexia, inflammation, congestive heart failure, and cancer, using in vitro and in vivo techniques. Actively researched and developed several of the techniques listed below, as well as wrote and implemented several animal protocols using rats and mice for research use. Served on the IACUC as scientific advisor, voting member, and administrator for 4 years. Led obesity project for 2 years (for drug discovery); led in-vivo section of DMPK group for 4 years (for preclinical development). Performed safety assessment and toxicology studies in support of research programs and summarized data by writing study reports for 1 year. All studies, both in vitro and in vivo, were performed in the spirit of GLP.
3/99-8/00
MCP – Hahnemann University, Philadelphia, PA
Department of Pharmacology & Physiology
SENIOR RESEARCH ASSOCIATE
Worked in a neuropsychopharmacology lab where I examined the role of serotonin and its receptors in relation to feeding and associated behaviors in rabbits, rats, and mice using in vitro and in vivo techniques. Actively researched and developed several of the techniques listed below. Assisted in coordinating the research effort of students and technicians within the lab. Acted as radiation safety officer for the lab.
6/98-2/99
University of Pennsylvania Medical Center, Philadelphia, PA
Psychiatry Department - Center for Neurobiology and Behavior
RESEARCH TECHNICIAN
Worked in a behavioral genetics lab where I studied the behavior of different genetic mutations affecting sleep and other behaviors, such as schizophrenia and anxiety, in mice.
6/96 - 5/98
Rutgers University, Camden, NJ
Biology Department
RESEARCH ASSISTANT
Worked in a neuroscience lab where I examined the molecular, biochemical, and physiological aspects of the GABA-A receptor in rats using in vitro and in vivo techniques.
LAB INSTRUCTOR/TEACHING ASSISTANT
Taught General Biology laboratories and helped instructors with related tasks such as proctoring and grading exams. Assisted in the coordination of colloquiums for the Biology Department.
EXPERIMENTAL TECHNIQUES:
In vivo:
Perfusions, Stereotaxic Surgery, Microdialysis, Feeding Studies, Sleep Studies, Conditioned Taste Aversion, Handling Laboratory Animals (Mice, Rats, Rabbits), Dosing Laboratory Animals (icv, ip, im, iv, sc, po), Behavioral Tests: General Observation, Startle/Pre-Pulse Inhibition/ Habituation Tests, Elevated Zero Maze/ Plus Maze Tests, Rotarod Test
In vitro:
Immunohistochemistry/Immunocytochemisty, Tissue/Cell Culture, Plating Cells, Treatment of Cultured Cells, Receptor Binding Assays, Receptor Autoradiography, RIA, EIA, ELISA, Protein Determination Assays, Cell Harvesting, TLC, Chloride Flux Assays, Membrane Preparations
Molecular:
Total mRNA Isolation, PCR, RT-PCR, Gel Electrophoresis
Other:
Handling Radioactive Material (3H, 125I, 14C, 32P, 35S), Microscopy (Bright Field, Dark Field, Phase Contrast, Fluorescent), Data Analysis, General Laboratory Procedures
PROFESSIONAL DEVELOPMENT:
3/10
Essentials of IACUC Administration
PRIM&R Pre-Conference Program, Baltimore, MD
11/06
Safety Pharmacology in Drug Development Short Course
The Center for Professional Innovation & Education, Malvern, PA
9/06
Predictive ADME/Tox Conference
CBI’s Business of Discovery Series, Washington, D.C.
8/05
Developability Assessment Short Course
The Center for Professional Advancement, New Brunswick, NJ
5/05
ADME & Drug Metabolism Short Course
The Center for Professional Advancement, New Brunswick, NJ
EDUCATION:
9/96 – 5/98
Rutgers University - Graduate School in Biology
Camden, NJ
M.S., Biology/Neuroscience
9/92 - 8/96
Rutgers University - Rutgers College
New Brunswick, NJ
B.A., Biology and Psychology
CERTIFICATIONS:
Certified Professional IACUC Administrator (CPIA)
COMPUTER SKILLS:
Microsoft Word/Excel/PowerPoint/Access/Outlook/Publisher/Project/Visio, WordPerfect, Graph Pad Prism, Sigma Plot/Stat/Graph, Ligand, Phase 3 Image Pro Plus, Adobe Photoshop, WinNonlin, QuickBooks, MAS90, ANIMA, AUP Builder, COLADA
PROFESSIONAL SKILLS:
Ability to organize and prioritize, work independently and meet deadlines.
Strong organizational & communication skills and attention to detail.
Experience in interacting with all levels of management.
Ability to handle confidential matters/information with discretion and diplomacy.
Ability to work in a fast paced, rapidly changing environment.
Ability to multi-task and manage multiple projects simultaneously.
LANGUAGES:
Fluent in English and Spanish
PUBILSHED ARTICLES:
Simansky, K.J., Dave, K.D., Inemer, B.R., Nicklous, D.M., Padron, J.M., Aloyo, V.J., Romano, A.G. A 5-HT2C Agonist Elicits Hyperactivity and Oral Dyskinesia with Hypophagia in Rabbits. Physiology & Behavior 2004; 82: 97-107.
Martin, J.V., Padron, J.M., Newman, M.A., Chapell, R., Leidenheimer, N.J., Burke, L.A. Inhibition of the Activity of the Native GABAA Receptor by Metabolites of Thyroid Hormones: Correlations with Molecular Modeling Studies. Brain Research 2004; 1004 (1-2): 98-107.
ABSTRACTS & PRESENTATIONS:
Setters, R.J., Padron, J.M., Shi, Y., Purma, P., Rajpurohit, R., Senadhi, S., Poore, D., Mirshahi, U., Shadiack, A.M., Sharma, S.D., Burris, K.D. (2005). Regulation of Body Weight in Diet-Induced Obese Mice by a Small Molecule Melanocortin-4 Receptor Agonist. Keystone Symposia – Obesity: Molecular Physiology and Genetics of the Control of Body Weight, Keystone, CO, January 27 – February 2, 2005.
Padron, J.M., Setters, R.J., Herbert, G.W., Hause, A.A., Shi, Y., Purma, P., Rajpurohit, R., Senadhi, S., Poore, D., Mirshahi, U., Shadiack, A.M., Sharma, S.D., Burris, K.D. (2004). Novel Small Molecule Melanocortin-4 Receptor Agonist Decreases Feeding and Body Weight without Aversive Effects, Illness or Erectile Activity. North American Association for the Study of Obesity 2004 Annual Scientific Meeting, Las Vegas, NV, November 14-18, 2004.
Setters, R.J., Padron, J.M., Shi, Y., Rajpurohit, R., Shadiack, A.M., Sharma, S.D., Burris, K.D. (2004). Regulation of Food Intake and Body Weight by Small Molecule Melanocortin-4 Receptor Agonists. 86th Annual Endocrinology Society Meeting: Neuroendocrinology of Energy Balance and Obesity, New Orleans, LA, June 16-19, 2004.
Shadiack, A.M., Herbert, G.W., Silvester, K.R., Padron, J.M. (2003). Elucidating the Mechanism of the Erectogenic Effects of PT-141, a Synthetic Melanocortin Agonist. 33rd Society for Neuroscience Meeting, New Orleans, LA, November 8-12, 2003.
Padron, J.M., Herbert, G.W., Mirshahi, U., Yang, W.H., Shi, Y., Cai, H., Rajpurohit, R., Sharma, S.D., Shadiack, A.M. (2002). Novel Agonists at Melanocortin Receptors Decrease Feeding and Body Weight in Rats. 32nd Annual Society for Neuroscience Meeting, Orlando, FL, November 2-7, 2002.
Shadiack, A.M., van Soest, T., Padron, J.M., and Pfaus, J.G. (2002). Facilitation of Sexual Solicitation in the Female Rat by the Melanocortin Analogue, PT-141. International Society for the Study of Women's Sexual Health (ISSWSH), Vancouver, Canada, October 10 – 13, 2002.
Padron, J.M., Aloyo, V.J., Harvey, J.A., and Simansky, K.J. (2000). Further Evidence that Stimulating 5-HT1B Receptors Inhibits Feeding in Rabbits. 30th Annual Society for Neuroscience Meeting, New Orleans, LA, November 4-9, 2000.
Simansky, K.J., Padron, J.M., Szajna, M.F., and Aloyo, V.J. (1999). The 5-HT2C/1B Agonist m-Chlorophenylpiperazine (mCPP) Reduces Eating by Rabbits. 29th Annual Society for Neuroscience Meeting, Miami Beach, FL, October 23-28, 1999.
Veasey, S.C., Padron, J.M., Kapfhamer, D., Benington, J., Sanford, L.D., and Bucan, M. (1999). A Complete Sleep Recording System Designed for the Study of the Genetics of Sleep Control in Mice. 13th Annual APSS (Sleep Research Society & American Sleep Disorders Association) Meeting, Orlando, FL, June 19-24, 1999.
Kapfhamer, D., Padron, J.M., Sanford, L.D., Veasey, S.C., and Bucan, M. (1999). Sleep:Wake Behavior in the Circadian Rhythm Mutant Earlybird. 13th Annual APSS (Sleep Research Society & American Sleep Disorders Association) Meeting, Orlando, FL, June 19-24, 1999.
Sanford, L.D., Lengeling, A., Kapfhamer, D., Padron, J.M., Leach, G., Veasey, S.C., and Bucan M. (1999). Sleep/Wake Assessment in Mouse Mutation with Inversion of Chromosome 5. 13th Annual APSS (Sleep Research Society & American Sleep Disorders Association) Meeting, Orlando, FL, June 19-24, 1999.
Kapfhamer, D., Alavizaheh, A., Padron, J.M., Veasey, S.C., Nolan, P., and Bucan, M. (1998). A Dominant Screen for Novel Rest:Activity Mutants in the Mouse. 12th International Mouse Genome Conference, Garmisch-Partenkirchen, Bavaria, September 29 – October 3, 1998.
Padron, J.M., Michener, T.A., Veasey, S.C., Sanford, L.D., and Bucan, M. (1998). Combined Mutagenesis Screen for Behavioral Mutations in Mice: Phenotypic Analysis of Sleep/Wake Behaviors in Mice. Mouse Molecular Genetics Conference, Cold Spring Harbor, NY, September 2-5, 1998.
Padron, J.M., Bilgin, N.M., and Martin, J.V. (1998). Thyroid Hormone Inhibition of GABAA Receptor-Mediated Chloride Flux is not Due to a Competitive Interaction at the GABA Recognition Site. New Jersey Academy of Science, Monmouth University, West Long Branch, NJ, April 18, 1998.
Bilgin, N.M., Padron, J.M., Burke, C., and Martin, J.V. (1998). Binding of a Ligand for the GABAA Receptor is Inhibited by Commonly Used Herbal Extracts. New Jersey Academy of Science, Monmouth University, West Long Branch, NJ, April 18, 1998.
Padron, J.M., Bilgin, N.M., and Martin, J.V. (1997). Effectiveness of Metabolites of Thyroid Hormones to Inhibit Muscimol-Stimulated Chloride Uptake to Rat Brain Synaptoneurosomes. 27th Annual Society for Neuroscience Meeting, New Orleans, LA, October 25-30, 1997.
Bilgin, N.M., Grunsfled, A.A., Padron, J.M., and Martin, J.V. (1997). Muscimol-stimulated Chloride Flux in Rat Brain Synaptoneurosomes is Inhibited by Thyroid Hormone. Philadelphia Chapter of the Society of Neuroscience Annual Meeting, Philadelphia, PA, May 23, 1997.
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