Biomedical Engineer/ R&D Scientist/ Clinical Researcher
Resume:
Sean P. Cullen
**** ******** **** ****, ******, NY 13039
***********@*****.***
SUMMARY:
Four years of research experience in the Biomedical Field at Undergrad and Graduate levels. Researched and designed individual research projects, and lead data analysis team of four for group project. Experience in biochemistry research laboratories, clinical research settings, working with an Institutional Review Board for approval of research involving human subjects, and programming for the visual and statistical analysis of data.
• Designer of new projects
• Team member
• Team leader
• Independent researcher
• Manage multiple projects
• Creative
• Knowledgeable in human anatomy and physiology
• Technical writer
EDUCATION:
SUNY Binghamton, MS in Biomedical Engineering GPA 3.87 December 2011
SUNY Geneseo, BS in Biophysics GPA 3.21 May 2009
RESEARCH:
• Designed research project and wrote protocol which was approved by the Institutional Review Board for clinical experiments to investigate the postural muscle tremors in the arm, aimed to provide a non-invasive quantitative diagnostic tool for Parkinson’s disease. My efforts resulted in the project being ready for clinical trials, 2010-2011.
• Worked on experimental design and troubleshooting for a PhD candidate’s dissertation research project investigating the electrical stimulation of mechanoreceptors on the plantar surface of the foot. Research goal was to non-invasively activate soleus pumping of the blood from the lower legs to the heart, reducing swelling in the lower legs and improving circulation. I was able to pinpoint several possible sources of error in the equipment and procedure, researched and suggested solutions to reduce errors, 2009.
• Independently searched for, selected, and tested program to analyze data images, and then led the analysis team for the Transmission Electron Microscopy data in order to observe the reversibility of fibrillogenesis. Fibrillogenesis of amyloid beta proteins is seen in the plaques in the brain of patients with Alzheimer’s disease. Research showed that altering the pH induced conformational changes in the proteins in the interfacial environment, and these results were published in the International Journal of Molecular Sciences, 2009.
• Performed Surface Plasmon Resonance Curve analysis of varying concentrations of Cytochrome-C and 20nm gold particles to investigate how gold particles affect the organization of the protein on the surface of the sensor, mimicking a simplified cell surface environment. Results suggested that increasing gold particle concentrations increase the organization in orientation of the protein on the gold surface of the sensor, and were presented on a poster during GREAT Day at SUNY Geneseo, 2008-09.
PUBLICATIONS:
Kazushige Yokoyama, Hyunah Cho, Sean P. Cullen, Matthew Kowalik, Nicole M. Briglio, Harold J. Hoops, Zhouying Zhao, Micheal A. Carpenter. "Microscopic Investigation of Reversibile Nanoscal Surface Size Dependent Protein Conjugation." International Journal of Molecular Sciences (2009): 2348-2366.
LABORATORY EXPERIENCE:
Clinical Lab experience setting up experiments, placing sensors on test subjects, and recording and analyzing data. College labs in Biology, Chemistry (General and Organic), and Physics (Analytical, Optics & Modern) used standard lab equipment (oscilloscope, signal generators, filters, etc.)
TECHNOLOGY EXPERIENCE:
Experienced using Biopac Student Lab for recording data, R for statistical analysis of data, programming in Python to automate analysis of data, Mathematica, MathCAD, Dynalign, Amber10, MATLAB, 3D modeling using Inventor and SolidWorks
Familiar with Microsoft Office Suite
HONORS AND AWARDS:
Beta Beta Beta, Biology Honor Society Geneseo Chapter, Inducted 2009
Sigma Pi Sigma, Physics Honor Society Geneseo Chapter, Inducted 2008
WORK EXPERIENCE:
• Pool Surgeons Inc. May-August 2009-2011
Pool maintenance and repair team, chemical testing and balancing, motor, filter, heater and liner repair and installation, designed new company logo and assisted with advertising and business plans.
• Victoria’s Secret January-May 2011
Associate on the shipment processing team.
• TA for Bioengineering 202: Biological Networks, in the Bioengineering Dept. at SUNY Binghamton January-May 2010
Graded assignments and exams, taught classes, held office hours to provide additional support to students.
• Onondaga County Department of Transportation May-August 2007, 2008
Member of road maintenance team using various equipment, directed traffic through construction zones.
• Tutored Access Opportunity Programs students in Physics and Biology at SUNY Geneseo 2006-2007
OTHER:
• Planet Fitness member 2010-Present
• Rochester Institute of Technology Drumline – Assisted with performance logistics and set-up at venues across NYS, 2010-2011
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