Clinical Scientist/Clinical Research Manager

Vikas Saini, MD, PhD

**** ******** ***, #**, *****, IL 60534 * Tel: 312-***-**** * Email: **********@*****.***

Job Objective

A challenging biomaterial engineer position where my bio-medical research, health maintenance and leadership skills can benefit for the company.

Qualifications Overview

• Well-qualified and technically-proficient Research Scientist with more than ten years laboratory experience and excellent academic qualifications.

• Experience in sophisticated research techniques and technologies: DNA, RNA & protein isolation, northern blot, western blot, microarrays, ELISA, RT-PCR, transfection, cloning, FACS, immunostaining, primary cell isolation, animal surgeries and telemedicine.

• Expertise in lab and clinical research, data collection/analysis and project management.

Education & Training

MD, Post Graduate Institute of Medical Sciences, Rohtak, India 1999

PhD, Bioengineering, University of Illinois at Chicago, Chicago, IL 2006

Postdoctoral Research Fellow, Dept. of Surgery, University of Chicago, Chicago, IL 2007

Postdoctoral Research Fellow, Dept. of Surgery, Loyola University Chicago, Chicago, IL 2010

Professional Experience

Research Associate, Department of Surgery, Loyola University Chicago, Chicago, IL 2008 - present

• Identified & characterized ubiquitin receptor on the surface of cells

Research Associate, Department of Surgery, University of Chicago, Chicago, IL 2006 - 2007

• Developed working cardiac hypertrophy model in mouse

• Isolated and cultured of rat, mouse, rabbit and human primary cardio-myocytes

• Performed langendorff perfusion, pacing and catheterization of rabbit and mouse

Research Assistant & Teaching Assistant, University of Illinois at Chicago, Chicago, IL 2000 - 2006

• Identified ‘ultrasound & shear stress’ regulated genes in bone cells

• Tested titanium implant sheets for biocompatibility in hip replacement

• Made three-dimensional cell scaffolds

• Managed home health monitoring system of cardiac patients

• Prepared quantum dots and analyzed spectrum of q-dots

Publications (>10)

1. Saini V, Marchese A, Majetschak M. “CXC chemokine receptor 4 is a cell surface receptor for extracellular ubiquitin.” Journal of Biological Chemistry, Mar 2010; doi: 10.1074/jbc.M110.103408.

2. Geng Q, Romero J, Saini V, Baker TA, Picken MM, Gamelli RL, Majetschak M. “A subset of 26S proteasomes is activated at critically low ATP concentrations and contributes to myocardial injury during cold ischemia.” Biochem Biophys Res Commun. 2009 Dec 25; 390(4):1136-41.

Patent

Inventor of provisional patent (Serial No. 61/222,267 filed by Loyola University Chicago in July 2009) – ‘Uses of ubiquitin and pharmacological compounds that bind to CXCR4’.

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