Project Development

CURRICULUM-VITAE

Sreenivasulu

*******.**@*****.***

Contact. No.:

+919*********

Permanent Address

S/O O.subbaiah,

Brahmadevam(vi&post),

Muthukur(mandal),

SPSR Nellore(Dt.).

A.P. PIN: 524346

Personal Data

Date of Birth:20-06-1989

Gender: Male

Nationality: Indian

Marital Status: Single

Languages Known: English Telugu.

Objective

To Work in a creative and challenging environment where I can take part in the growth of the organization by applying my abilities to the best where there is a room for upgrading skills and knowledge.

Education

• B.Pharmacy (2007-2011) from JNTU University,AP, with 67%

• Intermediate (2004-2006) from, Board of Intermediate, Hyderabad, A.P

with 68.9%

• S.S.C (2003-2004) from Board of Secondary Education, A.P with 69%

Technical Skills

Microsoft Tools : MS-Office

Operating Systems : Windows Family.

Web Related : Inter net concepts.

Projects Profile

TITLE : “Analytical Method Development And Validations of Sildenafil Citrate by

RP-HPLC”.

Project Description :

Title : Analytical Method Development And Validations of

Sildenafil Citrate by RP-HPLC.

Description :

A simple, selective, accurate reverse phase-high Performance Liquid Chromatographic (RP-HPLC) method was developed and validated for the analysis of Sildenafil Citrate in pharmaceutical formulations. Chromatographic separation achieved isocratically on a C18 column [Use Inertsil C18, 5µ , 150 mm x 4.6 mm] utilizing a mobile phase of acetonitrile/phosphate buffer (70:30, v/v, pH 7.0) at a flow rate of 0.8 ml/m with UV detection at

228 nm. The retention time was 4.087. The method is accurate (99.15-101.85%), precise (intraday variation 0.13-1.56% and inter-day variation 0.30-1.60%) and linear within range 0.1-30µg/ml (R2=0.999) concentration and was successfully used in monitoring left over drug. The detection limit of sildenafil citrate at a signal-to-noise ratio of 3 was 1.70ng/ml in formulations while quantification limit in drug was 5.40 ng/ml. The proposed method is applicable to stability

studies and routine analysis of sildenafil citrate in pharmaceutical formulations.

Keywords: Sildenafil Citrate, RP-HPLC method, Validation, Tablet dosage form

Extra-Curricular activities

1.Participated in school level science pare

2. Best player award in my SSC at Mandal level cricket tournament.

Sports & Hobbies

Hobbies : Reading books and Listening to music.

Sports : playing cricket.

Strengths

• Initiative, Innovative and Flexible, self – confident, Hard Working.

• Learn new things and positive minded.

Declaration

I here by declare that all the information mentioned above is true to the best of my knowledge.

O.Sreenivasulu

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