Biophysics Engineer for Optical Spectroscopy Systems

Andrey Bednov, Ph.D.

Albuquerque, US ***** • 409-***-**** • ********@*****.***

Professional Summary

Quality-driven team player with accuracy-focused and efficient approach, offering 30 years of multidisciplinary scientific/preclinical research expertise. Knowledgeable laboratory professional focused on optics, lasers, and biophotonics.

Proficient in educating personnel in laser radiation safety procedures. Adept at leading scientific teams.

Skilled in advanced NIR and Raman spectroscopy utilized for blood flow monitoring in cranial blood vessels conducted at Baylor College of Medicine. Experience in optical clearing of living bio tissue carried out at Medical School of Texas Tech University and Saratov State University.

Expertise in biomedical engineering and imaging, noninvasive laser diagnostics.

Broad experience in laser optoacoustics (of optical properties monitoring of phantom media and bio tissues; development of glucose sensor), advanced microscopy (light, fluorescent, and confocal) and electron microscopy (transmission and scanning) to study morphology of red blood cells and its changes at hyperosmotic conditions, optical coherence tomography (development of sol-gel glucose sensor), and spectroscopy (NIR, Raman) applied to propel groundbreaking studies at University of Texas Medical Branch.

Experience in Dynamic Light Scattering applied for monitoring of optical properties of multilayered polydisperse media performed at Department of Physics and Astronomy of University of Pennsylvania.

Expertise in laser-Doppler and speckle-interferometric method optimized for studies on bio fluids dynamics in microvessels carried out at Saratov State University and Saratov Branch of Russian Academy of Science. Having skills and extensive experimental experience in radiation studies and development of irradiation animal models to study the post irradiation effect in different animal species.

Skills

•Biomedical engineering and imaging

•Noninvasive biomedical diagnostics

•Independent scientific/pre-clinical research

•Lasers/Laser-Doppler/Laser Optoacoustics

•Microscopy (electron, fluorescent, confocal)

•Spectroscopy (NIR, Raman)

•Image reconstruction

•Control of tissue optical properties

•Optical clearing

•Leading scientific groups

•Cellular/molecular biology/cell culture

•Laboratory techniques

•Development of irradiation animal models

•Radiation studies

•Animal study/Animal surgery

•Data management and analysis

•Scientific Writing

Work History

Associate Research Scientist (Study Director/Radiation Countermeasures), 06/2023 to 10/2024

Lovelace Biomedical – Albuquerque, New Mexico; United States

•Developed irradiation animal models to study post irradiation effect on different animal species

•Conducted radiation studies using various radiation sources with ensured regulatory compliance by meticulously maintaining accurate documentation for all studies conducted

•Maintained radiation laboratory equipment to ensure efficient operations, reducing downtime due to malfunctions or repairs

•Performed/assisted in scheduled maintenance of radiation sources and lab equipment

•Led team of researchers efficiently, providing guidance and support to maximize productivity and achieve project goals

•Assisted in business development efforts by demonstrating technical knowledge during client meetings, leading to increased revenue opportunities

•Implemented rigorous quality control measures to ensure data integrity throughout each stage of research process

•Achieved significant progress in research projects by collaborating closely with multidisciplinary teams of scientists and engineers

Biology Course Lecturer, 05/2023 to 06/2023

Houston Vet Tech Institute – Houston, Texas; United States

•Designed and presented Biology course to veterinarian students

•Developed and implemented innovative teaching strategies to engage students in lectures and coursework

•Evaluated and revised lesson plans and course content to achieve student-centered learning

•Cultivated critical thinking skills through challenging assignments that required analysis, synthesis, and evaluation of information from various sources

Postdoctoral Research Associate, 07/2022 to 06/2023

Texas A&M University – Houston, Texas; United States

•Performed study of Post-Traumatic Stress Disorder (PTSD) with focus on regulation and dysregulation of stress response systems by means of cognitive and functional neuroimaging and neuroendocrine strategies

•Performed advanced data processing and statistical analysis

•Collaborated with multidisciplinary teams for successful project completion and timely results dissemination

•Designed, constructed and implemented research proposals, protocols and procedures

Scientific Consultant, 12/2018 to 05/2022

Saratov State University – Saratov; Russia

•Provided multi-level expertise in several aspects of biomedical research, in particular, diffusive processes, osmotic effect in biological tissues, and optical clearing

•Secured grant funding through persuasive proposal writing, enabling continued progress on critical projects

•Evaluated emerging technologies for potential adoption into existing research workflows, driving continuous improvement efforts

•Designed and executed experimental protocols, ensuring accurate collection of data and results.

•Conducted comprehensive literature reviews, providing valuable insights for project development and direction

•Spearheaded interdisciplinary collaborations, leveraging diverse expertise for enhanced problem- solving capabilities

Research Assistant Professor, 01/2017 to 06/2018

University of Texas, Permian Basin/Texas Technical University – Odessa, Texas; United States

•Developed and optimized ex vivo perfusion systems for study organ’s vascular physiology and drug transfer

•Developed biophysical models of bio tissues

•Performed complex evaluation of bio tissue perfusion at multiple levels: from physiological to molecular

•Coauthored peer-reviewed articles, establishing expertise within field of study

•Provided General Chemistry lectures to undergraduate UTPB students

Staff Scientist, 05/2012 to 06/2016

Baylor College of Medicine – Houston, Texas; United States

•Developed and optimized ex vivo perfusion systems to study organ’s vascular physiology and drug transfer

•Studied reactivity of placenta to vasoactive agents

•Performed quantitative analysis of drug transfer trough complex bio tissues using ex vivo perfusion systems

•Designed and developed experimental setup to study adhesive force of bio patches cold-welded to bio tissues

•Studied vascular physiology of singular blood vessels at pressurized and “flow-through” perfusion modes using Pressure Servo System

•Developed novel experimental protocols, leading to more accurate and reliable results

•Secured grant funding for critical projects, ensuring continued support for groundbreaking studies.

•Managed laboratory inventory efficiently, effectively organizing supplies and minimizing waste of resources

•Published peer-reviewed articles in prestigious journals, increasing visibility of organization’s cutting-edge research

•Presented research findings at international and national conferences, displaying organization’s commitment to scientific advancement

•Utilized state-of-the-art equipment and analytical tools to generate high-quality data in various research projects

•Collaborated with multidisciplinary teams to drive breakthrough discoveries in scientific field

Post-Doctoral Fellow, 08/2008 to 02/2011

University of Texas, Medical Branch - Galveston, Texas

•Conducted independent research running a number of cellular biology projects

•Utilized and expanded cell culturing skills and standard lab technique experience

Research Associate, 05/2005 to 07/2008

University of Texas, Medical Branch - Galveston, Texas

Conducted research dedicated to the study of experimental ocular Myasthenia Gravis (MG).

Performed vestibuloocular reflex study in mice using video oculography.

Research Assistant/Graduate Research Assistant, 01/1999 to 04/2005

University of Texas, Medical Branch - Galveston, Texas

Performed study on Epstein-Barr virus (EBV) re-activation in astronauts after landing: stimulation of EBV gene expression in EBV-positive cell lines followed by antibody analysis using immunofluorescence methods

Carried out analysis of three-dimensional cell cultures affected by EBV using scanning electron microscopy

Took active part in the cooperative NASA-UTMB research project: “Study of the EB virus re-activation in astronauts” with Department of Space Medicine, Johnson Space Center (Houston, Texas)

Participated in development of Laser Optoacoustics (LOA) imaging system to study optical properties of complex polydisperse media, materials and tissues

Studied physiological, biochemical and physical aspects of glucose interaction with biological tissue (collagenous tissue, blood) using laser optoacoustics

Performed monitoring of tissue optical properties at variable physiologic and pathologic conditions using LOA

Took part at development of prototype of noninvasive glucose LOA sensor

Developed combined laser optoacoustics - fluorescence method for colon cancer diagnostics

Visiting Scientist, 9/1998 to 01/1999

University of Pennsylvania - Philadelphia, Pennsylvania

Designed and developed biophysical model of burned skin

Adapted and utilized Dynamic Light Scattering to precise measurements of burned skin depth

Research Scientist II, 09/1992 to 09/1998

Russian Academy of Sciences, Precise Mechanics and Control Institute - Saratov, Russia

Performed study of blood and lymph flow dynamics in vivo using laser Doppler method

Performed correlation analysis of scattered light intensity for the qualitative and quantitative characterization of dynamic parameters of bio fluids (Mathcad)

Education

Ph.D.: Biophysics/Biomedical Engineering, 06/2006

Saratov State University - Saratov, Russia

Master of Science: Physiology and Biophysics, 12/2003

University of Texas, Medical Branch - Galveston, Texas

Master of Science: Physics/Optics/Laser Physics, 07/1992

Saratov State University - Saratov, Russia

Bachelor of Science: Physics/Optics, 07/1990

Saratov State University - Saratov, Russia

Additional Information

U.S. Citizen

Languages

Russian

Native or Bilingual

English

Full Professional

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