Analytical & Formulation Development Scientist

SHAHIR SARASIYA

Bridgewater NJ (Open to Relocate) +1-404-***-**** **************@*****.*** LinkedIn Formulation Development Scientist Analytical Development Scientist Pharmaceutical R&D HPLC Method Development Preformulation & Physicochemical Characterization Spectroscopy GLP/GMP PROFESSIONAL SUMMARY

Ph.D.-trained analytical chemist with 5+ years of combined industrial and academic experience spanning analytical method development, physicochemical characterization, and small-molecule pharmaceutical research. Develops and optimizes HPLC and spectroscopic methods to evaluate purity, stability, and product quality, and has characterized 20+ small-molecule compounds for solubility, optical behavior, and structure-property relationships that inform formulation feasibility. Applies computational modeling (Spartan, Gaussian, Maestro) alongside bench experimentation to predict molecular properties affecting solubility and stability, accelerating compound selection decisions. Experienced in regulated laboratory operations, including SOP development, GLP compliance, instrument calibration, LIMS documentation, laboratory investigations, and CAPA support. Recognized for translating analytical data into clear technical reports, publications, and IP disclosures while collaborating across chemistry, biology, and engineering teams. Targeting roles as a Formulation Development Scientist, Analytical Development Scientist, or Pharmaceutical R&D Scientist.

CORE EXPERTISE

Formulation & Pharmaceutical Development: Preformulation Studies (Solubility, Stability, Physicochemical Profiling) • Drug Substance Characterization • Structure-Property Relationship Analysis • Formulation Strategy Support for Small Molecules

• Stability-Indicating Analytical Approaches • Technical Reporting • Cross-Functional Collaboration Analytical Development & Characterization: Analytical Method Development & Optimization • Chromatographic Separation & Purity Assessment • Impurity Profiling & Compound Identification • Spectroscopic Characterization • Quantitative

& Qualitative Data Analysis • Sample Preparation & Extraction • Experimental Design & Method Troubleshooting TECHNICAL SKILLS

Analytical & Characterization Techniques: HPLC (Method Development, Purity Analysis, Quantification), GC, NMR Spectroscopy (Structure Elucidation), UV-Visible Spectroscopy, Fluorescence Spectroscopy, IR Spectroscopy, TLC, Flash Chromatography

Formulation-Relevant Laboratory Skills: Solubility Assessment, Physicochemical Property Evaluation, Compound Stability Monitoring, Sample Preparation for Analytical Testing, Purification & Isolation of Drug Candidates, Structure-Property Analysis for Formulation Feasibility

Laboratory Operations & Quality Systems: SOP Development & Execution, GLP Compliance, GMP Awareness, Laboratory Investigations, CAPA Support, Instrument Calibration & Maintenance, Analytical Equipment Troubleshooting, Chemical Inventory & Safety Management, Data Integrity

Computational & Data Tools: ChemDraw, Spartan '20, Gaussian, Maestro, TopSpin, PerkinElmer UV WinLab, Cary WinFLR, LIMS, EndNote, Microsoft Office Suite

PROFESSIONAL EXPERIENCE

Georgia State University Graduate Research Assistant (CDT Fellow) Atlanta, GA Jan 2023 – Present

• Characterize 20+ small-molecule compounds through solubility, optical property, and structure-property evaluation to support formulation-relevant decision-making.

• Develop and optimize HPLC and spectroscopic methods to assess compound purity, stability, and performance across experimental conditions.

• Design and execute experiments evaluating molecular behavior under varying solvent, pH, and environmental conditions to generate preformulation insights.

• Apply computational tools (Spartan, Gaussian, Maestro) to predict molecular properties influencing solubility, stability, and formulation feasibility.

• Perform structure elucidation and purity confirmation using NMR, UV-Vis, fluorescence, and IR spectroscopy, and isolate drug candidates via flash chromatography and TLC monitoring.

• Author technical reports, peer-reviewed publications, and IP disclosures documenting analytical findings and formulation- relevant conclusions.

• Collaborate with multidisciplinary chemistry, biology, and engineering teams to integrate analytical data into broader pharmaceutical research objectives.

• Mentor undergraduate and graduate researchers on analytical techniques, data interpretation, and laboratory best practices. Georgia State University Laboratory Inspector, Chemistry Atlanta, GA Aug 2023 – Aug 2025

• Audited research laboratories for compliance with EHS regulations, SOPs, and chemical handling and storage standards.

• Supported quality systems through documentation review, inspection reporting, and CAPA-related corrective actions.

• Identified and escalated compliance gaps, partnering with laboratory personnel to implement sustainable corrective measures.

• Reinforced safe, compliant laboratory practices consistent with regulated pharmaceutical environments. Alpha Analytical Analytical Chemist Westborough, MA Jun 2021 – Jan 2023

• Executed quantitative analytical testing using HPLC and related instrumentation, ensuring accuracy, reproducibility, and data integrity across high sample volumes.

• Prepared and extracted samples using standardized and validated methods supporting environmental and chemical analysis programs.

• Conducted quality control procedures including calibration verification, standards, blanks, spikes, and duplicates in compliance with QA requirements.

• Maintained, calibrated, and troubleshot analytical instrumentation to sustain operational reliability and minimize downtime.

• Documented and reported analytical results in LIMS in accordance with regulatory and quality standards.

• Supported laboratory investigations and out-of-specification reviews, contributing to continuous improvement of analytical workflows.

• Trained laboratory personnel on analytical techniques, SOPs, and safety protocols. ADDITIONAL PROFESSIONAL EXPERIENCE

Georgia State University Instructor of Record Atlanta, GA Aug 2025 – Present

• Deliver laboratory instruction emphasizing analytical techniques, experimental design, and scientific data interpretation. Georgia State University Teaching Assistant Atlanta, GA Jan 2022 – Present

• Provide hands-on training in analytical techniques, instrumentation, and laboratory safety across chemistry courses. Biotechnic & Histochemistry Junior Editor Jan 2024 – Present

• Review scientific manuscripts for analytical rigor, experimental design, and quality of data interpretation. EDUCATION

Ph.D. in Organic Chemistry GPA: 4.05/4.30 Aug 2023 – Aug 2026 Georgia State University, Atlanta, GA

Center of Diagnostic and Therapeutic (CDT) Research Fellow Master of Science in Chemistry GPA: 4.24/4.30 Jan 2022 – May 2023 Georgia State University, Atlanta, GA

Thesis: Synthesis and Optical Properties of Red-Shifted Squaraine Dyes Containing Perimidine Moiety as Potential Optoacoustic Imaging Agents

Bachelor of Science in Chemistry GPA: 4.16/4.30 Aug 2018 – Dec 2021 Georgia State University, Atlanta, GA

SELECTED PUBLICATIONS & INTELLECTUAL PROPERTY

• Sarasiya, S., Henary, M. Red-Shifting Squaraine Dyes in the Near-Infrared Region Using the Perimidine Heterocycle: Synthesis and Optical Properties. RSC Advances, 2026.

• Ser, J., Baek, M. J., Shamim, M., Sarasiya, S., et al. Dynamic Microenvironment-Responsive Fluorophores Enable Rapid Tumor Margin Imaging. Submitted to Nature Chemical Biology.

• Sarasiya, S., Henary, M. Exploration of NIR Squaraine Contrast Agents Containing Various Heterocycles: Synthesis, Optical Properties and Applications. Pharmaceuticals, 2023.

• IP Disclosure submitted to Georgia State University Legal Office, 2025. SELECTED SCIENTIFIC PRESENTATIONS

Presented research at 15+ national and regional scientific conferences, including the Biological Stain Commission Conference, SERMACS, the Southeastern Chemical Biology & Drug Discovery Symposium, and the Graduate Conference for Research, Scholarship & Creative Activity.

AWARDS & HONORS

• Department of Chemistry Chair's Research Award

• Department of Chemistry Graduate Teaching Award

• Center of Diagnostic and Therapeutic (CDT) Research Fellowship

• 1st Place and 3rd Place Research Poster Awards

• Department of Chemistry Golden Award for Undergraduate Research LEADERSHIP & SERVICE

Research Mentor, Georgia State University: Mentored undergraduate researchers in laboratory techniques, experimental design, and data analysis.

Symposium Judge: Evaluated scientific presentations and provided feedback on methodology and data interpretation. Module Assistant Instructor, Georgia Science Olympiad: Supported laboratory-based competitions through evaluation and event coordination.

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