Translational Cardiovascular Pharmacologist PhD

Puneet Kaur Randhawa, PhD

U.S. Permanent Resident Work Visa Not Required

Email: ********.********@*****.***; Phone: 571-***-**** PROFESSIONAL SUMMARY

PhD-trained Pharmacologist with 10+ years of translational biomedical research experience, specializing in cardiovascular pharmacology, preclinical drug development, and molecular biology. Proven track record of designing and executing ex vivo and in vivo models, mechanistic target validation, and regulatory-compliant research (ICH-GCP, GLP). Author of 30+ peer- reviewed publications, 3 book chapters, and 1 academic textbook. Adept at graduate mentorship, multidisciplinary collaboration, and securing data integrity for high-impact journals

(IF 8+).

EDUCATION

Doctor of Philosophy (PhD) – Pharmaceutical Sciences / Pharmacology Punjabi University, Patiala, India Sep 2013 – Feb 2018

• Dissertation: Molecular Mechanisms of Remote Ischemic Preconditioning in Cardioprotection

• Advisor: [Dr. Amteshwar Singh Jaggi, PhD]

Master of Pharmacy (M.Pharm) – Pharmacology

Punjabi University, Patiala, India Jul 2011 – May 2013

• Thesis: Investigating the Role of Passiflora incarnata in Ameliorating Epileptic Episodes

• Advisor: [Rajesh Kumar Goel, PhD]

Bachelor of Pharmacy (B.Pharm)

Punjabi University, Patiala, India Jul 2007 – May 2011 ACADEMIC & RESEARCH APPOINTMENTS

(Reverse chronological order)

Associate Professor

Amritsar Group of Colleges (AGC), Amritsar, India Jun 2022 – May 2026

• Supervise graduate and postgraduate research projects, guiding thesis design, execution, and manuscript development.

• Lead experimental protocol design, ensuring rigorous data integrity and reproducibility across all laboratory studies.

• Foster multidisciplinary collaborations bridging basic pharmacology and translational cardiovascular models.

• Publish original findings in high-impact, peer-reviewed international journals. Postdoctoral Fellow

University of Central Florida (UCF), Orlando, FL, USA Jan 2020 – May 2022

• Conducted translational cardiovascular research focusing on ischemia-reperfusion injury mechanisms.

• Designed and validated in vitro and ex vivo pharmacological models (Langendorff perfusion, cardiomyocyte assays).

• Executed advanced molecular techniques: Western blotting, immunohistochemistry, ROS assays, fluorescence microscopy, and agarose gel electrophoresis.

• Performed statistical analyses (GraphPad/SPSS) and interpreted complex experimental datasets for publication.

• Prepared scientific reports, manuscripts, and collaborated with international, interdisciplinary research teams.

Assistant Professor

Khalsa College of Pharmacy, Amritsar, India Apr 2018 – Jun 2019

• Supervised graduate student research and taught core pharmacology courses.

• Designed laboratory curricula and ensured compliance with institutional safety protocols.

• Contributed to departmental research output through peer-reviewed journal publications. SELECTED RESEARCH HIGHLIGHTS & CONTRIBUTIONS

• Investigated the molecular signaling pathways (e.g., RISK, SAFE) underlying remote ischemic preconditioning to identify novel cardioprotective therapeutic targets.

• Established and optimized ex vivo ischemia-reperfusion models to screen pharmacological interventions in rodent cardiac tissue.

• Integrated echocardiography and histopathological endpoints to quantify cardiac functional recovery and tissue salvage.

• Authored a comprehensive academic textbook: Fundamental Aspects of Experimental Cardiology, used in graduate-level curricula.

RECENT PUBLICATIONS & SCHOLARLY OUTPUT

Randhawa PK, Gupta D, Hanifa M, Bajgai B, Sehajpal S, Jaggi S, Bali A. Eugenol: A promising therapeutic terpenoid against ischemia-reperfusion injury. EXCLI J. 2026 Jan 19;25:222-237. doi: 10.17179/excli2025-9036. PMID: 41834914; PMCID: PMC12982868. Bajgai B, Suri M, Singh H, Hanifa M, Bhatti JS, Randhawa PK, Bali A. Naringin: A flavanone with a multifaceted target against sepsis-associated organ injuries. Phytomedicine. 2024 Jul 25;130:155707. doi: 10.1016/j.phymed.2024.155707. Epub 2024 May 10. PMID: 38788393. Hanifa M, Singh M, Randhawa PK, Jaggi AS, Bali A. A focus on Rho/ROCK signaling pathway: An emerging therapeutic target in depression. Eur J Pharmacol. 2023 May 5;946:175648. doi: 10.1016/j.ejphar.2023.175648. Epub 2023 Mar 8. PMID: 36894049. Randhawa PK, Rajakumar A, Futuro de Lima IB, Gupta MK. Eugenol attenuates ischemia- mediated oxidative stress in cardiomyocytes via acetylation of histone at H3K27. Free Radic Biol Med. 2023 Jan;194:326-336. doi: 10.1016/j.freeradbiomed.2022.12.007. Epub 2022 Dec 13. PMID: 36526244; PMCID: PMC10074330.

(Full bibliography available upon request. Bolded author indicates primary author.)

• Peer-Reviewed Articles: 30+ research and review articles in international journals

(including journals with Impact Factors >8).

• Book Chapters: 3 published book chapters on cardiovascular pharmacology and experimental models.

• Academic Books: 1 authored textbook (Fundamental Aspects of Experimental Cardiology).

PRESENTATIONS & INVITED TALKS

(Please populate with specific conferences; placeholders provided)

• Oral Presentation: [“21 st International Conference on Clinical & Experimental Cardiology”], [2017]- “Investigating the involvement of glycogen synthase kinase-3β and gap junction signaling in TRPV1 and remote hind preconditioning-induced cardioprotection”

• Oral Presentation: [49th Annual Conference of the Indian Pharmacological Society

(IPS-CON 2016)], 2016- “Involvement of TRPV1 ion channels in remote

• hind limb preconditioning-induced cardioprotection in rats” TEACHING & MENTORING EXPERIENCE

• Graduate/Postgraduate Mentoring: Extensive experience supervising B.Pharm and M. Pharm research, including thesis committee participation, experimental troubleshooting, and career guidance.

• Course Instruction: Delivered lectures in cardiovascular pharmacology, molecular pharmacology, and preclinical drug discovery.

• Workshop Leadership: Conducted hands-on training in Langendorff perfusion, Western blotting, and statistical data analysis for junior researchers. TECHNICAL & PROFESSIONAL COMPETENCIES

Category Expertise

Molecular & Cellular

Biology

Western blotting, Immunohistochemistry (IHC), Cell viability assays, Agarose gel electrophoresis, Histology, Cryo-sectioning, Fluorescence microscopy.

Preclinical

Cardiovascular

Models

Langendorff isolated heart perfusion, Ex vivo ischemia-reperfusion models, Echocardiography, ROS/reactive oxygen species assays. Data Analysis &

Software

Statistical analysis (GraphPad Prism, SPSS), MS Office Suite

(Word, Excel, PowerPoint), Literature review databases (PubMed, Scopus).

Regulatory & Clinical

Research

ICH-GCP E6 R3 guidelines, Data quality assurance.

PROFESSIONAL SERVICE & REVIEWING ACTIVITIES

(Please add specific journals you review for, or committees you serve on)

• Ad Hoc Reviewer for Frontiers in Cardiovascular Medicine, Canadian Journal of Physiology and Pharmacology.

CERTIFICATIONS

• ICH-GCP E6 R3 (Good Clinical Practice) – [Year of certification/Expiration] REFERENCES

1. Dr. Amteshwar Singh Jaggi (Community Pharmacist at PharmaChoice (Prosper Pharmacy), Surrey, Canada, Former Professor at Punjabi University, Patiala Ph.No.-+1-236-***-****,+919*********

Email: **************@*****.***

2. OlenaKondrachuk (University of Michigan Ann Arbor, United States) PhNo.-+1-830-***-**** Email- ********@***.*****.*** 3. Deepti ( Kelly Education Orlando, Fl, UnitedStates PhNo.-+1-407-***-**** *****-***************@*****.***

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