Neuroscience Translational Scientist and Educator

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Jacob Hammer

South Bend, IN • 574-***-**** • ********@**.*** • www.linkedin.com/in/jacob-hammer PROFESSIONAL SUMMARY

PhD-trained neuroscientist with expertise in translational neurobiology, pharmacogenomics, and oncology- and disease-relevant signaling pathways, combined with frontline clinical experience as an Advanced Emergency Medical Technician. Proven ability to engage healthcare professionals through high-quality scientific exchange, translating complex clinical and preclinical data into clear, actionable insights. Experienced in developing relationships with clinicians and multidisciplinary stakeholders, delivering evidence-based education, and generating field-relevant insights to inform strategy. Published author and experienced presenter seeking to contribute to Medical Affairs as a Medical Science Liaison. CORE COMPETENCIES

• Healthcare Professional (HCP) Engagement

• Stakeholder Relationship Development

• Clinical Insight Generation & Communication

• Clinical & Scientific Exchange

• Clinical & Translational Data Interpretation

• Evidence-Based Education & Presentation

• Therapeutic Landscape Analysis

• Cross-Functional Collaboration

• Regulatory & Compliant Communication

• Adaptability & Rapid Technical Learning

RELEVANT EXPERIENCE

Graduate Researcher

University of Notre Dame – South Bend, IN August 2020 – February 2026

• Independently led translational neuroscience research evaluating disease-relevant biological mechanisms, generating insights applicable to therapeutic development and clinical strategy

• Delivered 20+ scientific presentations to multidisciplinary audiences including clinicians and translational researchers, facilitating peer-level scientific exchange and responding to complex questions on emerging data and therapeutic mechanisms

• Conducted ongoing therapeutic landscape and literature surveillance, synthesizing emerging data into actionable scientific insights to inform research direction and experimental design

• Translated complex experimental findings into clinically relevant insights tailored to diverse stakeholders

• Collaborated cross-functionally with biologists, imaging specialists, and clinical researchers to contextualize preclinical findings within disease and treatment frameworks

• Generated and integrated multi-level biological datasets to evaluate targeted therapeutic outcomes relevant to neurological injury and disease

• Authored 2 peer-reviewed manuscripts in high-impact journals (PLOS Genetics, Cell Reports)

• Mentored Bio-REU undergraduate student (Summer 2024) and served as Teaching Assistant (Fall 2022), delivering structured scientific education, strengthening communication and training capabilities Laboratory Research Technician

University of Notre Dame – South Bend, IN June 2019 – August 2020

• Investigated the influence of tumor microenvironment characteristics and signaling on cancer progression and therapeutic resistance, contributing to translational oncology research

• Supported cross-functional collaborations and data integration across research laboratories to advance scientific objectives and publication (Cell Death & Disease)

• Synthesized experimental findings into clear scientific narratives to support internal stakeholders and manuscript development

• Mentored an undergraduate researcher in experimental design, scientific reasoning, and data interpretation Graduate Research Assistant

Manchester University, College of Pharmacy – Fort Wayne, IN February 2019 – May 2019

• Evaluated pharmacogenomic variability in drug response, applying personalized medicine principles to therapeutic decision-making

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• Interpreted gene-drug interactions and translated findings into clinically relevant insights for healthcare and academic stakeholders

• Communicated pharmacogenomic findings, including statistical interpretation and clinical trial relevance, to faculty and clinical collaborators to support informed decision-making and medical strategy Undergraduate Laboratory and Teaching Assistant

Manchester University – North Manchester, IN August 2016 – May 2017

• Assisted in teaching 3 classes; Advanced Human Physiology Lab, Fundamentals of Human Anatomy, and Fundamentals of Human Physiology, reinforcing foundational clinical and biological concepts

• Led group learning sessions and clarified complex material to 95 students of varied knowledge levels HEALTHCARE EXPERIENCE

Advanced Emergency Medical Technician (Hospital & Pre-Hospital Settings) Lutheran Hospital of Indiana Emergency Department June 2017 – Aug 2018 Tri-County Ambulance Service May – August 2016; March – August 2018

• Delivered frontline patient care in high-acuity emergency and transport settings, communicated time- sensitive clinical information to physicians and HCPs to support real-time clinical decision-making

• Collaborated with multidisciplinary care teams in both emergency department and pre-hospital environments, adapting to distinct clinical workflows and care coordination dynamics

• Applied clinical judgment in fast-paced environments, recognizing patient priorities and supporting efficient, informed decision-making by healthcare teams

• Developed working knowledge of regional healthcare systems, referral pathways, and medical centers throughout Northern Indiana, supporting awareness of territory and care dynamics PUBLICATIONS & SCIENTIFIC PRESENTATIONS

Selected Publications:

Hammer, J.N., Smith C.J. The regenerative period of somatosensory nerves is closed by a DCC signaling axis. PLOS Genetics. February 2026.

Koh, Z.M., Arceo, R.A., Hammer, J.N., et al. An ultrastructural map of a spinal somatosensory circuit reveals the potential for astroglial modulation. Cell Reports. January 2026. Selected Presentations:

John V. O’Connor Biochemistry & IBMS Research Conference, Notre Dame, IN May 2025 Hammer, Jacob. The regenerative period of somatosensory nerves is closed by a DCC signaling axis. [Oral] Biological Sciences Cell Seminar Series, Notre Dame, IN April 2025 Hammer, Jacob. The regenerative period of somatosensory nerves is closed by a DCC signaling axis. [Oral] Molecular Mechanisms of Neuronal Connectivity Conference, Long Island, NY September 2024 Hammer, Jacob. Somatosensory nerve regeneration is limited by a DCC-cAMP-Rac1 signaling axis. [Poster] EDUCATION

University of Notre Dame

Ph.D. in Neuroscience (Integrated Biomedical Sciences Program) February 2026 Manchester University, College of Pharmacy

M.S. in Pharmacogenomics, Cum Laude May 2019

Manchester University

B.S. in Biology-Chemistry; Exercise and Sport Science May 2017 HONORS & AWARDS

Young Investigator Award, Midwest Tumor Microenvironment Meeting, July 2020 Outstanding Presenter, Manchester University Spring Research and Innovative Seminar, May 2019

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