Ph D Associate Dean
Resume:
LIN GAO
Concord MA *1742
**********@*****.***
Active Oklahoma Optometry License number: 3297
EDUCATION
VA Brockton
Residency July 2024- Dec 2024, Supervisor: Kevin Toolin OD. New England College of Optometry
OD May 2024
University of Rochester, Rochester, NY
Ph.D/Pathology July 2012, Research Advisor: Regis J. O’Keefe, MD/Ph.D Associate Dean for Clinical Affairs, URMC, Wehle Professor and Chair, Chair, Department of Orthopaedics and Rehabilitation
• Loss of TAK1 in Cartilage Leads to Osteoarthritis Like Phenotype University of Rochester, Rochester, NY
MS/Pathology 2009, Research Advisor: Regis J. O’Keefe, MD/Ph.D Associate Dean for Clinical Affairs, URMC, Wehle Professor and Chair, Chair, Department of Orthopaedics and Rehabilitation
• The Dual Roles of BMP Type I Receptor ALK3 in Cartilage Jilin University, Changchun, China
MS/Biochemistry and Molecular Biology 2003, Research Advisor: Min Hong, MD/Ph.D Associate Dean, Professor
• The Effect of Morphine on behavioral changes and Purine Catabolism Norman Bethune University of Medical Sciences, Changchun, China MD 2000 (ECFMG certification 5/26/2011)
POSTDOCTORAL TRAINING
University of Rochester, Rochester, NY
Post-Doctoral Associate, 1st August 2012 – 31st July 2014 Advisor: Regis J. O’Keefe, MD/Ph.D Associate Dean for Clinical Affairs, URMC, Wehle Professor and Chair, Chair, Department of Orthopaedics and Rehabilitation
University of Rochester, Rochester, NY
Post-Doctoral Associate, 15th August 2015-14th August 2017 Advisor: John Looney, MD Professor Department of Allergy, Immunology and Rheumatology FACULTY APPOINTMENTS
University of Rochester, Rochester, NY
Research Assistant Professor of Medicine, 15th August 2017-30th April 2020 Department of Allergy, Immunology and Rheumatology
HONORS AND AWARDS
Young Investigator Travel Grant, American Society for Bone and Mineral Research 2013 Annual Meeting
Best Poster Travel Award, Center for Musculoskeletal Research 2013 Symposium Lin Gao
F1000Prime, My paper “TAK1 regulates SOX9 expression in chondrocytes and is essential for postnatal development of the growth plate and articular cartilages” Journal of Cell Science, 2013 (DOI: 10.3410/f.718151720.793486335), has been selected for F1000Prime. It was recommended as being of special significance in its field by a Faculty Member Frank Beier. RESEARCH ACTIVITIES
Grant: LRA-Pfizer, the Role of Interferon beta in SLE, PI John Looney, 300000 USD for 2 years. Grant: GRANT12541245-Department of Defense, Therapeutic Targeting of Senescent Cells in Lupus, PI John Looney, 150000 USD for 1 year.
EDITORIAL ASSIGNMENTS IN PROFESSIONAL JOURNALS
Reviewer in Plos One and Bone.
PUBLICATIONS
Lin Gao, Mary OConnell, Maria Allen, Jane Liesveld, Andrew McDavid, Jennifer H Anolik, Richard J Looney
Bone marrow mesenchymal stem cells from patients with SLE maintain an interferon signature during in vitro culture, Cytokine 2020 Aug:132:154725. doi: 10.1016/j.cyto.2019.05.012. Epub 2019 May 29 Lin Gao, Jane Liesveld, Jennifer Anolik, Andrew Mcdavid, Richard John Looney IFN β signaling inhibits osteogenesis in human SLE bone marrow, Lupus 2020 Aug;29(9):1040-1049. doi: 10.1177/0961203320930088. Epub 2020 Jun 9
Lin Gao, Maria Slack, Jennifer L Barnas, Andrew McDavid, Jennifer Anolik, R John Looney Cell Senescence in Lupus, Curr Rheumatol Rep 2019 Jan 14;21(2):1. doi: 10.1007/s11926-019-0800-6 Lin Gao, Anna K Bird, Nida Meednu, Kristin Dauenhauer, Jane Liesveld, Jennifer Anolik, R. John Looney,
Human SLE bone marrow mesenchymal stem cells (BMSCs) have a senescence-associated secretory phenotype (SASP) mediated by a MAVS-IFNβ feedback loop, Arthritis and Rheumatology. doi: 10.1002/art.40142. Epub 2017 May 4
Richard John Looney, Jennifer Anolik, Lin Gao
Mavs Mediates a Senescence Associated Secretory Phenotype By Inducing Interferon Beta Expression in Human SLE Bone Marrow Stromal Cells, Journal of Allergy and Clinical Immunology 139(2):AB269 DOI:10.1016/j.jaci.2016.12.868
Lin Gao, Tzong-jen Sheu, Yufeng Dong, Michael Zuscik, Edward M Schwarz, Matthew J Hilton, Regis J O’Keefe, and Jennifer H Jonason,
TAK1 Regulates SOX9 Expression in Chondrocytes and is Essential for Postnatal Development of the Growth Plate and Articular Cartilages, J Cell Sci. 2013 Dec 15;126 (Pt 24):5704-13. doi: 10.1242/jcs.135483. Epub 2013 Oct 21
Tian-Fang Li, Lin Gao, Tzong-Jen Sheu, Erik R Sampson, Lisa M. Flick, Yrjo T. Konttinen, Di Chen,Edward M. Schwarz, Michael J. Zuscik, Jennifer H. Jonason and Regis J.O’Keefe, Aberrant hypertrophy in Smad3-deficient murine chondrocytes is rescued by restoring transforming growth factor- activated kinase ß1/activating transcription factor 2 signaling, Arthritis and Reumatism. 2010 Aug: 62(8) 2359-2369
Chang Liu, Jian-kai LIU, Mu-jie KAN, Lin Gao, Hai-ying FU, Hang ZHOU and Min HONG, Morphine enhances purine nucleotide catabolism in vivo and in vitro, Acta Pharmacologica Sinica. 2007: 28(8) Haiying Fu, Min Hong, Lin Gao, Hang Zhou, Lianzhi Zhang, Effects of morphine on gene expression of key enzymes for protein and cucleic acid catabolism in rat liver, Journal of Jilin University (Medicine Edition).2004: 30(6)
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