Ph D United States

PRIYANKA KUMAR, Ph.D.

**** ************* *** **, ***

Washington DC, United States

Mobile: +1-202-***-****

Email: *************@*****.***

EDUCATION

Degree Subject Institute/University Year

Ph.D. Biotechnology Savitribai Phule Pune University, India 2011

M.S. Biochemistry University of Delhi, New Delhi, India 2005

B.S. Biochemistry University of Delhi, New Delhi, India 2003

PERSONAL STATEMENT

I am a highly motivated researcher with a strong passion for exploring the intricacies of cell signaling. My background in cancer biology, coupled with specialized training in cell and molecular biology, has equipped me with the skills and expertise necessary for impactful research. As a doctoral fellow at NCCS, Pune, India, I played a key role in several projects, including the transcriptional regulation of the osteopontin gene in a cervical cancer model, utilizing molecular biology tools. Additionally, I contributed to a cancer drug discovery program focused on developing target-specific synthetic drugs for cervical cancer.

RESEARCH EXPERIENCE

2014 Postdoctoral fellow at National Institute of Health, Bethesda, MD

2013 Senior resident at Vardhman Mahavir Medical College, New Delhi, India

2011-2012 Postdoctoral fellow at University of California, Riverside, USA

TECHNICAL SKILLS

Cell Culture, Cell viability, proliferation, migration, co-migration, invasion and clonogenicity assay, ELISA, immunoprecipitation, western blot,, zymography, electrophoresis mobility shift assay (EMSA), primer designing, RT-PCR, cloning and protein expression, site directed mutagenesis, protein purification, plasmid isolation, siRNA design and transfection, confocal microscopy, flow-cytometry, tumor stromal and tumor endothelial interaction assays, in-vitro angiogenesis assay, invasion assay, animal handling, tumor kinetics and metastasis study using In Vivo Imaging System (IVIS), histopathology of tumor samples and human clinical sample analysis.

RESEARCH INTEREST

I’d like to pursue my career as a researcher in the field of fundamental cellular & molecular signaling and transcriptional gene regulation.

ORAL/POSTER PRESENTATION

1.Oral presentation in 3rd International Symposium on Translational cancer research: cell signaling and cancer therapy held in Bhubaneswar from December 18-21, 2009.

2.Poster entitled “Transcriptional regulation of osteopontin (OPN) by trichostatin A (TSA), a Histone deacetylase inhibitor” was presented in “International symposium on Novel strategies for targeted prevention and treatment of cancer” held in JNU Delhi from December 19-20, 2008.

3.Participated in 30th All India Cell Biology Conference & Symposium on “Molecules to Compartments: Cross-Talks and Networks” held in New Delhi from February 2-4, 2007.

4.Participated in 10th Asian conference on Transcription and Transcription assembly held in Bangalore from January 13-16, 2008.

PEER-REVIEWED PUBLICATIONS

1.Priyanka Sharma, Santosh Kumar and Gopal C. Kundu. Transcriptional regulation of human osteopontin promoter by histone deacetylase inhibitor, trichostatin A in cervical cancer cells. Molecular Cancer, July 7, 9 (1), 178, 2010.

2.Muyu Xu, Priyanka Sharma, Songqin Pan, Sohail Malik, Robert Roeder, Martinez E. Core promoter-selective function of HMGA1 and Mediator in Initiator-dependent transcription. Genes and Development, 25(23): 2513-24, 2011.

3.Kumar S, Sharma P, Kumar D, Chakraborty G, Gorain M, Kundu GC. Functional characterization of stromal osteopontin in melanoma progression and metastasis PLoS One. 2013 Jul 23;8(7): Print 2013.

4.Santosh Kumar, Harshal Patil, Priyanka Sharma, Dheeraj Kumar, Dasari S, Puranik VG, H Thulasiram and Gopal C. Kundu. Andrographolide Inhibits Osteopontin Expression and Breast Tumor Growth Through Down Regulation of PI3 kinase/Akt Signaling Pathway. Curr Mol Med 2012 Sep;12(8):952-66.

5.Ahmed M, Behera R, Chakraborty G, Jain S, Kumar V, Sharma P, Bulbule A, Kale S, Kumar S, Mishra R, Raja R, Saraswati S, Kaur R, Soundararajan G, Kumar D, Thorat D, Sanyal M, Ramdasi A, Ghosh P, Kundu GC. Osteopontin: a potentially important therapeutic target in cancer. Expert Opin Ther Targets. 2011 Sep;15(9):1113-26.

6.Saurabh J Pradhan, Rosalin Mishra, Priyanka Sharma and Gopal C. Kundu. Quercetin and sulforaphane in combination suppress the progression of melanoma through the down-regulation of matrix metalloproteinase-9. Experimental and therapeutic medicine. 2010 Nov;1(6):915-920. Epub 2010 Aug 26.

7.Goutam Chakraborty, Shalini Jain, Reeti Behera, Mansoor Ahmed, Priyanka Sharma, Vinit Kumar and Gopal C. Kundu. The Multifaceted Roles of Osteopontin in Cell Signaling, Tumor Progression and Angiogenesis. Curr Mol Med, 6: 819-830, 2006.

8.Bandopadhyay M, Bulbule A, Butti R, Chakraborty G, Ghorpade P, Ghosh P, Gorain M, Kale S, Kumar D, Kumar S, Totakura KV, Roy G, Sharma P et al. Osteopontin as a therapeutic target for cancer. Expert Opin Ther Targets. 2014 Aug;18(8):883-95.

Contact this candidate