Life Sci, Pharma, Biotech, Drug Discovery, Diagnostics, Molecular Biol
Resume:
SHAMBHUNATH BOSE, Ph.D.
Nationality: Indian
Email: *********@*****.***
********@*****.***
Current Position
April, 2024- To Date
Consultant.
ASTA Corporation,
Yeongtong-Gu, Suwon-Si,
Gyeonggi-Do,
South Korea
(Working from Bengaluru, India)
Email:
*********@*****.***
********@*****.***
Mobile: +91-991*******
2
Organization Details
April, 2024- To Date
Consultant,
ASTA Corporation,
Yeongtong-Gu, Suwon-Si,
Gyeonggi-Do,
South Korea
(Working from Bengaluru, India)
Clinical and Molecular Diagnosis of Diseases using MALDI-TOF-Mass Spectrometry- based Techniques and Omics Approach; Antimicrobial Resistance; Bioinformatics-guided Microbial Identification; Lab-on-a-hip, Digital Diagnostics; Prototype Designing and Commercialization
September, 2022- May, 2024
Professor (Academics & Research),
Department of Life Sciences,
Sri Sathya Sai University for Human Excellence,
Navanihal, Okali Post,
Kamalapur, Kalaburagi 585313,
Karnataka,
India
Research & Teaching in Molecular Biology; Biotechnology; Cell Biology; Immunology
March, 2022-August, 2022
Professor, Department of Life Sciences,
Graphic Era (Deemed to be University),
Bell Road, Clement Town Dehradun, Uttarakhand,
India
Research & Teaching in Molecular Biology; Biotechnology; Cell Biology; Immunology 3
July, 2021- January, 2022
Professor (Academics & Research)
Department of Life Sciences,
Sri Sathya Sai University for Human Excellence,
Navanihal, Okali Post,
Kamalapur, Kalaburagi 585313,
Karnataka,
India
Research & Teaching in Molecular Biology; Biotechnology, Cell Biology; Immunology
January, 2019- June, 2021
Freelance Scientific Consultant,
BexPharm Healthcare Ltd.,
1201, Seoul Forest Park, Halla Sigma Valley, Seongdong-gu, Seoul,
South Korea
Research and Development of Natural Medicines for Wide Therapeutic Areas; Preclinical and Clinical Studies; Strategic Planning and Business Promotion
March, 2016- December, 2018
Chief, Research, NosQuest Inc.,
910 USPACE 1A, Bundang-gu, Seongnam-si,
Gyeonggi-do,
South Korea
Website: http://nosquest.com/en/main/main.php
Clinical and Molecular Diagnosis of Diseases including Cancer using MALDI-TOF- Mass Spectrometry- based Techniques and Omics Approach; Bioinformatics-guided Microbial Identification; Lab-on-A-Chip; Digital Diagnostics, Prototype Designing and Commercialization; Clinical Trials 4
October, 2009 – February, 2016
Foreign Faculty Member,
Dongguk University,
813 Siksa-dong, Goyang-si,
Gyeonggi-do, 410-773,
South Korea
Website: http://www.dongguk.edu
Basic & Fundamental Aspects of Life Sciences, Biomolecules & Chemical Biology, Cell
& Molecular Biology, etc.; Metabolic Disorders including Diabetes and Obesity, Cancer, Inflammation including Neuroinflammation, Neurodegenerative Disorders such as Alzheimer’s Disease; Natural Medicines, Anti-Oxidants, Chemical Biology, Nutrigenomics; Mechanism of Actions of Natural Medicines against a Wide Range of Diseases and Disorders; Influence of Host Gut Microbiota on Disease and Response to Drugs; Pre-Clinical Screening and Clinical Investigations
2008 – 2009
Associate Director, Biology
Jubilant Biosys Ltd. (a renowned state-of-the-art research-based drug discovery organization serving top multinational pharmaceutical companies)
# 96, industrial Suburb, 2nd Stage, Yeshwanthpur,
Bangalore - 560 022,
India
Website: http://www.jubilantbiosys.com
Engaged in Drug Discovery- Biology Research for Preclinical Evaluation of New Chemical Entities, High Throughput Screening (HTS), Development of Cell-Based Assays, in vitro and in vivo Studies
2007–2008
Senior Scientist
Applied Surface Technology Asia (ASTA) Inc.
Yeongtong-gu, Suwon-si, Gyeonggi-do,
5
South Korea
Corporate Office: 2 Executive Dr, Suite 580, Fort Lee, NJ 07024. USA Involved in Research in Major Therapeutic Segments in Diabetes, such as Insulin Signaling, Insulin Resistance, Insulin Glycation, and Inhibition of Protein Tyrosine Phosphatase 1B (PTP 1B)
2004–2007
Senior Scientist
Proteonik, Inc.
Gyeonggi Technopark, Songrog gu,
Ansan-si, Gyeonggi-do,
South Korea
Proteonik, inc. was initially established as a sister concern of Green Cross Corporation, a renowned Biopharmaceutical company in South Korea Engaged in Research in Major Therapeutic Segments in Diabetes, such as Insulin Signaling, Insulin Resistance, Insulin Glycation, and Inhibition of Protein Tyrosine Phosphatase 1B (PTP 1B)
2000–2004
Post-Doctoral Fellow,
Department of Biochemistry, Institute of Biomedicine, University of Helsinki, Helsinki,
Finland
Website: http://www.biomedicum.fi
Research on Cancer/Apoptosis; Elucidated Molecular Mode of Action of Histone and Antimicrobial Peptides as Apoptotic Inducers in Cancerous Cells; Development of Sensitive Liposome-based Techniques for Identification and Characterization of Apoptotic Cells; Clinical Trials
6
1998 -2000
Senior Research Scientist
New Drug Discovery-Biology
Zydus-Cadila Ltd. (an innovative global pharmaceutical company that discovers, develops, manufactures and markets a broad range of healthcare products)
Zydus Tower, Satellite Cross Roads,
Ahmedabad, Gujarat,
India
Website: http://www.zyduscadila.com
Engaged in Drug Discovery Research in the Following Areas: Preclinical Screening of Drugs using Different Animal Models; Pharmacokinetic Profiling of New Chemical Entities; Basic Research on Anti-Diabetic Candidates
1995 -1998
Research Scientist
New Drug Discovery-Biology
Wockhardt Ltd. (a global pharmaceuticals and biotechnology major) Wockhardt Towers, Bandra-Kurla Complex,
Bandra (East), Mumbai - 400 051, Maharashtra,
India
Website: www.wockhardt.com
Engaged in Drug Discovery Research. Preclinical Screening of Drugs using Different Animal Models. Pharmacological Evaluation of Anti-Bacterial and Anti- Malarial Candidates, Hepatitis B Surface Antigen (HbsAg) and Recombinant Erythropoietin (EPO)
7
Synopsis
A vast experience in teaching and research in Life-Sciences, Pharmaceuticals & Biotechnology, Drug Discovery, Clinical Trials in the Universities and industries both in India and abroad.
Extensive experience in working with prime therapeutic segments: Diabetes, Obesity, Cancer (breast and ovarian), Inflammation including Neuroinflammation, Neurodegenerative disorders such as Alzheimer’s disease both at pre-clinical and clinical levels.
Vast technical knowledge in cell signaling, omics-based studies, single nucleotide polymorphism (SNP), cloning and sequencing, transfection, gene expression using PCR, Real-Time PCR, DNA microarray, PCR array, Western Blotting, and MALDI- TOF Mass Spectrometry, etc.
Detailed investigations on the influence of gut microbial-host interaction on the onset and progression of diseases and response to the drugs, personalized medicine. These studies were conducted using real-time PCR, DNA microarray, PCR array, PCR-denaturing gradient gel electrophoresis fingerprinting, pyrosequencing, etc., as well as different bioinformatics tools for functional annotation and analyses of correlation, principal coordinate, and clustering.
Extensive experience in working with radioisotope-based techniques like radioreceptor assay, radioimmunoassay & radioligand binding assay.
Adequate exposure to fluorescence techniques, confocal laser microscopy, and fluorescence- based assays, histology, and immunohistochemistry.
In-depth knowledge in protein isolation, purification, and characterization.
High throughput screening (HTS) and studies of mechanism(s) of action of therapeutic candidates, emphasizing cell signaling using most sophisticated automated systems, robotics, and cell-based and cell-free assay techniques.
In vitro and in vivo preclinical screening and profiling of drug candidates, structure- activity relationship studies, toxicological evaluation, lead identification and optimization, bioequivalence and metabolic studies of the candidate drug molecules. 8
Research Projects Completed & Ongoing
• March 2016-Till- to-date
Clinical and Molecular Diagnosis of Diseases using MALDI-TOF-Mass Spectrometry-Based Techniques and Omics Approach
NosQuest, Inc., South Korea
2011-2013
Clinical Microbial Analysis
Dongguk University, South Korea
• 2010-2013
New Drug R&D, Clinical Trials
Dongguk University, South Korea
• 2009-2011
Clinical Investigations
Dongguk University, South Korea
• 2009-2010
Nutrigenomics, Clinical Trials
Dongguk University, South Korea
• 2008-2009
Research on Drug Discovery
Jubilant Biosys Limited, India
9
Awards and Scholarships
Very recently, I have been nominated and selected as a full member of Sigma Xi (The Scientific Research Honor Society (ΣΞ), USA by both the Director and Manager of Membership and Chapters of this society. Sigma Xi is the oldest international association for multidisciplinary researchers. This is a highly prestigious, non-profit honor society for scientists and engineers worldwide. The selection was purely based on an exceptional contribution to the research community. This society recognizes researchers for the values they hold in high esteem, including more than 200 Nobel Laureates. It has more than 500 chapters which are found in the universities and colleges, government laboratories and commercial research centers in North America and around the world. 10
11
Recipient of prestigious Junior and Senior Research Fellowships (Dr. K.S. Krishnan DAE) from Bhabha Atomic Research Centre (BARC), Trombay, Mumbai, Department of Atomic Energy, Govt. of India in for the period of 1990- 1993.
Recipient of Postdoctoral Fellowship from Institute of Biomedicine, University of Helsinki, Finland in 2000.
Senior Research Fellowship from the Department of Biotechnology, Govt. of India in 1993.
Junior Research Fellowship from the University Grants Commission, Govt. of India for the period of 1989-1990.
Qualified Graduate Aptitude Test in Engineering (GATE) from Indian Institute of Technology (IIT), India in 1989.
12
Consultant/Expert
Worked as a New Product Consultant (NPC) for ‘Small Molecule Tools in Cell Biology’, in Sigma-Aldrich
Corporation, St. Louis, MO, USA. The company grew
through various acquisitions until it had over 9,600 employees and was listed on the Fortune 1000. The company is headquartered in St. Louis and has operations in approximately 40 countries.
Worked as an external expert on the ‘Future Trends Study of Obesity’ for Sterling Brands, Los Angeles, CA, USA. The company is headquartered in New York with offices in San Francisco, Los Angeles and Cincinnati. Its clients include many of the world’s most respected organizations including Procter
& Gamble, Pfizer, Nestlé, Amazon, Levis, Pepsi, Kellogg's, Gillette, Disney, Bayer, Google, Visa, Time Warner, T-Mobile, Abbott Laboratories, etc. The company became part of the Omnicom family in 2008.
Consultant/Member of Society of Industry Leaders, Standard & Poor's, Vista Research Inc., a division of the McGraw-Hill Companies, USA.
Expert in Pharmaceutical and Life Science Research and Manufacturing, New Drug Discovery, Therapeutic Strategy of Intota, which is a business-to-business service of Guideline, USA.
13
Academia
Ph.D. in Biochemistry from Visva Bharati University, India with prestigious Junior and Senior Research Fellowships (Dr. K.S. Krishnan DAE) from Bhabha Atomic Research Centre (BARC), Trombay, Mumbai, India.
Reviewers of Journals
Scientific Reports (Nature Publishing Group)
Journal of Ethnopharmacology (Elsvier B.V.)
Phytotherapy Research (John Wiley & Sons, Inc.)
Journal of Medicinal Food (Mary Ann Liebert, Inc.)
Biomedicine & Pharmacotherapy (Elsvier B.V.)
IT Skills
Operating System: MS-DOS, WINDOWS 10,
Office Tools: MS Word, Excel, PowerPoint, Photoshop
Software program: FoxPro and Oracle with PL/SQL & Developer 2000 14
International Publications
A. Peer-Reviewed Journals:
Sl
No
Author name Title Journal name Year and
Volume
No.
Indexing Impact
Factor
1. E. Seong, Shambhunath
Bose, S. Y. Han, E. J.
Song, M. Lee, Y. Nam, and
H. Kim
(Clinical Investigation)
Positive influence of gut
microbiota on the effects of
Korean red ginseng in
metabolic syndrome: a
randomized, double-blind,
placebo-controlled clinical trial.
EPMA Journal
Springer Nature
Switzerland AG
ISSN (print): 1878-5077;
ISSN (online): 1878-5085
2021;
12(2):177-
197
doi:
10.1007/s1
3167-021-
00243-4
Science Citation
Index Expanded,
Scopus, PubMed
Central, EMBASE
8.836
2. Shambhunath Bose, and
J. Cho
Targeting chaperones, heat
shock factor-1, and unfolded
protein response: Promising
therapeutic approaches for
neurodegenerative disorders
Ageing Research
Reviews
Elsevier B.V.,
The Netherlands
ISSN: 1568-1637
2017; 35:
155-175
Science Citation
Index Expanded,
Scopus, PubMed/
Medline, Current
Contents, etc.
11.79
3. Shambhunath Bose, S.
Jeon, T. Eom, M. Y. Song,
and H. Kim
Evaluation of the in vitro and in
vivo protective effects of
unfermented and fermented
Rhizoma coptidis formulations
against lipopolysaccharide
insult.
Food Chemistry
Elsevier B.V.,
The Netherlands
ISSN: 0308-8146
2012;
135(2):
452-459
Science Citation
Index, Scopus,
Current Contents,
Chemical Abstracts,
EMBASE, etc.
9.231
4. Shambhunath Bose, M.
Y. Song, J. K. Nam, M. J.
Lee, and H. Kim
In vitro and in vivo protective
effects of fermented
preparations of dietary herbs
against lipopolysaccharide
insult.
Food Chemistry
Elsevier B.V.,
The Netherlands
ISSN: 0308-8146
2012;
134(2):
758-765
Science Citation
Index, Scopus,
Current Contents,
Chemical Abstracts,
EMBASE, etc.
9.231
5. S. W Hong*, J. W. Yoo*,
Shambhunath Bose*, J.
H. Park, K. Han, S. Kim, H.
Understanding the molecular
aspects of oriental obesity
pattern differentiation using
Journal of Translational
Medicine
Springer Nature
2015; 13:
331
Science Citation
Index Expanded,
Scopus, PubMed,
8.440
15
Kim, and D. K. Lee
(*These authors
contributed equally to
this work)
(Clinical Investigation)
DNA microarray. Switzerland AG
ISSN: 1479-5876
Current Contents,
CAS, EMBASE
6. S. J. Lee, Shambhunath
Bose, J. G Seo, W. S.
Chung, C. Y. Lim, and H.
Kim
(Clinical Investigation)
The effects of co-administration
of probiotics with herbal
medicine on obesity, metabolic
endotoxemia and dysbiosis: A
randomized double-blind
controlled clinical trial.
Clinical Nutrition
Elsevier Ltd., and
European Society for
Clinical Nutrition, USA
ISSN: 0261-5614 (Print)
2014;
33(6): 973-
981
Science Citation
Index Expanded,
Scopus, PubMed/
Medline, Chemical
Abstracts, Current
Contents, etc,
7.643
7. A. Hussain, Shambhunath
Bose, J. H. Wang, M. K.
Yadav, G.B. Mahajan, and
H. Kim
Fermentation, a feasible
strategy for enhancing
bioactivity of herbal medicines.
Food Research
International
Elsevier B.V.,
The Netherlands
ISSN: 0963-9969
2016; 81:
1-16
Science Citation
Index, Scopus,
PubMed/ Medline,
Elsevier BIOBASE,
Chemical Abstracts
7.425
8. M. A. Farah,
Shambhunath Bose, and
Y. Kim
Analysis of molecular
interaction of glycated insulin
with insulin receptor by MALDI-
TOF mass spectrometry and
Surface Plasmon Resonance
(SPR).
Molecular & Cellular
Proteomics
American Society for
Biochemistry and
Molecular Biology
Print ISSN 1535-9476;
Online ISSN 1535-9484
2004;
3 (10):
S126
Science Citation
Index, Scopus,
PubMed, Index
Medicus, Current
Contents, BIOSIS,
Chemical Abstracts
Service
7.381
9. P. Ghosh, S. Ghosh,
Shambhunath Bose, and
S. Bhattacharya
Glutathione depletion in the
liver and kidney of Channa
punctatus exposed to carbaryl
and metacid-50.
Science of the Total
Environment
Elsevier B.V.,
The Netherlands
ISSN: 0048-9697
1993; 134:
Suppl. 1,
641-645
Science Citation
Index, Science
Citation Index
Expanded, Scopus
10.75
10. S. Ghosh, Shambhunath
Bose, P. Ghosh and S.
Bhattacharya
Monitoring of xenobiotic stress
in fish by an acute phase
protein.
Science of the Total
Environment
Elsevier B.V.,
The Netherlands
ISSN: 0048-9697
1993; 134:
Suppl. 2,
1279-1282
Science Citation
Index, Science
Citation Index
Expanded, Scopus
10.75
16
11. Shambhunath Bose, P.
Ghosh, S. Ghosh and S.
Bhattacharya
Distribution kinetics of inorganic
mercury in the subcellular
fractions of fish liver.
Science of the Total
Environment
Elsevier B.V.,
The Netherlands
ISSN: 0048-9697
1993; 134:
Suppl. 1,
533-538
Science Citation
Index, Science
Citation Index
Expanded, Scopus
10.75
12. Y. Choi, Shambhunath
Bose, N. Shin, E. J. Song,
Y. D. Nam, and H. Kim
Lactate-fortified Puerariae
Radix fermented by
Bifidobacterium breve improved
diet-induced metabolic
dysregulation via alteration of
gut microbial communities.
Nutrients
MDPI, Basel, Switzerland
ISSN: 2072-6643;
CODEN: NUTRHU
2020;
12(2): 276
Science Citation
Index Expanded,
Scopus, PubMed,
Chemical Abstracts
(ACS), EMBASE,
Biological Abstracts
6.706
13. K. Han, Shambhunath
Bose, J. H. Wang, B. S.
Kim, M. J. Kim, E. J. Kim,
and H. Kim
(Clinical Investigation)
Contrasting effects of fresh and
fermented kimchi consumption
on gut microbiota composition
and gene expression related to
metabolic syndrome in obese
Korean women.
Molecular Nutrition &
Food Research
John Wiley & Sons, Inc.,
USA
ISSN: 1613-4133
2015;
59(5):
1004-1008
Science Citation
Index, Science
Citation Index
Expanded, Scopus,
BIOSIS, CAS, Current
Contents
6.575
14. K. Han*, Shambhunath
Bose*, Y. M. Kim, Y. W.
Chin, B. S. Kim, J. H.
Wang, J. H. Lee, and H.
Kim
(*These authors
contributed equally to
this work)
(Clinical Investigation)
Rehmannia glutinosa reduced
waist circumferences of Korean
obese women possibly through
modulation of gut microbiota.
Food & Function
Royal Society of
Chemistry
ISSN: 2042-650X
2015; 6(8):
2684-2692
Science Citation
Index Expanded,
Scopus, PubMed,
CAS
6.317
15. A. Ansari, Shambhunath
Bose, Y. You, S. Park, and
Y. Kim
Molecular mechanism of
microbiota metabolites in
preterm birth: Pathological and
therapeutic insights
International Journal of
Molecular Sciences
MDPI, Basel, Switzerland
ISSN: 1661-6596 (print);
ISSN: 1422-0067;
CODEN: IJMCFK
2021;
22(15):
8145
https://doi.
org/10.339
0/ijms2215
8145
Science Citation
Index Expanded,
Scopus, PubMed,
Chemical Abstracts
(ACS), EMBASE
6.208
17
16. M. Yang, Shambhunath
Bose, S. K. Lim, and H.
Kim
Preventive effects of Pyungwi-
san against dextran sulfate
sodium- and Clostridium
difficile-induced inflammatory
bowel disease in mice.
International Journal of
Molecular Sciences
MDPI, Basel, Switzerland
ISSN: 1661-6596 (print);
ISSN: 1422-0067;
CODEN: IJMCFK
2019;
20(24):
6346
Science Citation
Index Expanded,
Scopus, PubMed,
Chemical Abstracts
(ACS), EMBASE
6.208
17. N. R Shin, Shambhunath
Bose, J. H. Wang, A. Z.
Flos Lonicera combined with
metformin ameliorates
Frontiers in Microbiology
Frontiers Media SA,
2017; 8:
2271
Science Citation
Index Expanded,
6.064
Ansari, S. K. Lim, Y. W.
Chin, H. S. Choi, and H.
Kim
hepatosteatosis and glucose
intolerance in association with
gut microbiota modulation.
Switzerland
ISSN: 1664-302X
Scopus, PubMed,
Chemical Abstracts
Service, Google
Scholar
18. J. H. Wang, Shambhunath
Bose, S. N. Rae, Y. W.
Chin, Y. H. Choi, and H.
Kim
Pharmaceutical impact of
Houttuynia cordata and
metformin combination on high-
fat-induced-metabolic
disorders: Link to intestinal
microbiota and metabolic
endotoxemia.
Frontiers in
Endocrinology, section
Diabetes
Frontiers Media SA,
Switzerland
Electronic ISSN: 1664-
2392
2018; 9:
620
Science Citation
Index Expanded,
Scopus, PubMed,
Web of Science,
MEDLINE
6.055
19. Shambhunath Bose, and
J. Cho
Role of chemokine CCL2 and it
receptor CCR2 in
neurodegenerative diseases.
Archives of Pharmacal
Research
Springer Nature
Switzerland AG
ISSN (print): 0253-6269;
ISSN (web): 1976-3786
2013;
36(9):
1039-1050
Science Citation
Index Expanded,
Scopus, Medline,
Current Contents,
EMBASE, Chemical
Abstracts
6.010
20. S. . Park, N. R. Shin, M.
Yang, Shambhunath
Bose, O. Kwon, D. H.
Nam, J. H. Lee, E. J. Song,
Y. D. Nam, and H. Kim
(Clinical Investigation)
A clinical study on the
relationship among insomnia,
tongue diagnosis, and oral
microbiome.
The American Journal of
Chinese Medicine
World Scientific
Publishing Co., Inc., USA
ISSN (print): 0192-415X;
ISSN (web): 1793-6853
2022;
50(3):
773-797
Science Citation
Index Expanded,
Scopus, PubMed,
BIOSIS, Current
Contents, EMBASE
6.005
18
21. A. Ansari, Shambhunath
Bose, S. K. Lim, J. H.
Wang, Y. H. Choi, and H.
Kim
Combination of Scutellaria
baicalensis and metformin
ameliorates diet-induced
metabolic dysregulation in mice
via the gut-liver-brain axis.
The American Journal of
Chinese Medicine
World Scientific
Publishing Co., Inc., USA
ISSN (print): 0192-415X;
ISSN (web): 1793-6853
2020;
48(6):
1409-1433
Science Citation
Index Expanded,
Scopus, PubMed,
BIOSIS, Current
Contents, EMBASE
6.005
22. N. R. Shin, Shambhunath
Bose, Y. Choi, Y. M. Kim,
Y. W. Chin, E. J. Song, Y.
D. Nam, and H. Kim
Anti-obesity effect of
Fermented Panax notoginseng
is mediated via modulation of
appetite and gut microbial
population.
Frontiers in
Pharmacology
Frontiers Media SA,
Switzerland
ISSN: 1663-9812
2021;
12:665881
doi:
10.3389/fp
har.2021.6
65881
Science Citation
Index Expanded,
PubMed, Scopus,
Chemical Abstracts
5.988
23. A. Ansari, Shambhunath
Bose, J. K. Patra, S. N.
Rae, D. W. Lim, K. W. Kim,
J. H. Wang, Y. M. Kim, Y.
W. Chin, and H. Kim
A controlled fermented-
Samjunghwan herbal formula
ameliorates nonalcoholic-
hepatosteatosis in HepG2 cells
and OLETF rats.
Frontiers in
Pharmacology
Frontiers Media SA,
Switzerland
ISSN: 1663-9812
2018;
9:596
Science Citation
Index Expanded,
PubMed, Scopus,
Chemical Abstracts
5.988
24. D. H. Kwon,
Shambhunath Bose, M.
Y. Song, M. J Lee, C. Y.
Lim, B. S. Kwon, and H. J.
Kim
(Clinical Investigation)
Efficacy of Korean red ginseng
by single nucleotide
polymorphism (SNP) in obese
women: Randomized, double-
blind, placebo-controlled trial.
Journal of Ginseng
Research
Elsevier B.V.,
The Netherlands
ISSN: 1226-8453
2012;
36(2): 176-
189
Science Citation
Index Expanded,
Scopus, PubMed
Central, EMBASE
5.735
25. Md. Moniruzzaman,
Shambhunath Bose, Y. M
Kim, Y.W Chin, and J. Cho
The ethyl acetate fraction from
Physalis alkekengi inhibits LPS-
induced pro-inflammatory
mediators in BV2 cells and
inflammatory pain in mice.
Journal of Ethno-
pharmacology
Elsevier B.V.,
The Netherlands
ISSN: 0378-8741
2016; 181:
26-36
Science Citation
Index, Scopus,
PubMed, BIOSIS,
Current Contents,
Chemical Abstracts,
EMBASE
5.195
26. S. Jeon, Shambhunath
Bose, J. Hur, K. Jund, Y.
K. Kim, K. S. Cho, and B.
S. Koo
A modified formulation of
Chinese traditional medicine
improves memory impairment
and reduces Aβ level in the Tg-
APPswe/PS1dE9 mouse model
of Alzheimer’s disease.
Journal of Ethno-
pharmacology
Elsevier B.V.,
The Netherlands
ISSN: 0378-8741
2011;
137(1):
783-789
Science Citation
Index, Scopus,
PubMed, BIOSIS,
Current Contents,
Chemical Abstracts,
EMBASE
5.195
19
27. N. R. Shin, Shambhunath
Bose, J. H. Wang, Y. D.
Nam, E. J. Song, D. W.
Lim, Y. S. Lim, H. B. Kim,
Y. S. Lim, H. S. Choi, and
H. Kim
Chemically or surgically
induced thyroid dysfunction
altered gut microbiota in rat
models.
The FASEB Journal
John Wiley & Sons, Inc.,
USA
ISSN (print): 0892-6638;
ISSN (online): 1530-6860
2020;
34(6):8686
-8701
Science Citation
Index Expanded,
Scopus, PubMed,
Biological Abstracts,
BIOSIS, Current
Contents
5.191
28. D. W. Lim, Shambhunath
Bose, J. H. Wang, H. S.
Choi, Y. M. Kim, Y. W.
Chin, S. H. Jeon, J. E. Kim,
and H. Kim
Modified SJH alleviates FFAs-
induced hepatic steatosis
through leptin signaling
pathways.
Scientific Reports
Nature Publishing
Group, UK
ISSN: 2045-2322 (Online)
2017; 7:
45425
Science Citation
Index Expanded,
Scopus, PubMed
4.996
29. J. H. Wang*,
Shambhunath Bose*, H.
Fermented Rhizoma
Atractylodis Macrocephalae
Scientific Reports
Nature Publishing
2015;
5:8391
Science Citation
Index Expanded,
4.996
G. Kim, K. S. Han, and H.
Kim
(*These authors
contributed equally to
this work)
alleviates high fat diet-induced
obesity in association with
regulation of intestinal
permeability and microbiota in
rats.
Group, UK
ISSN: 2045-2322 (Online)
Scopus, PubMed
30. A. Z. Ansari,
Shambhunath Bose, M.
K. Yadav, J. H. Wang, Y.
K. Song, S. G. Ko, and H.
Kim
CST, an herbal formula, exerts
anti-obesity effects through
brain-gut-adipose tissue axis
modulation in high-fat diet fed
mice.
Molecules
MDPI,
Basel, Switzerland
ISSN: 1420-3049;
CODEN: MOLEFW
2016;
21(11):
1522
Science Citation
Index Expanded,
Scopus, PubMed,
Current Contents,
EMBASE, Chemical
Abstracts
4.927
31. Y Choi, Shambhunath
Bose, J Seo, J-H Shin, D
Lee, Y Kim, S G Kang, and
H Kim
Effects of live and pasteurized
forms of Akkermansia from the
human gut on obesity and
metabolic dysregulation
Microorganisms
MDPI, Basel, Switzerland
ISSN 2076-2607; CODEN:
MICRKN
2021;
9(10):2039
. doi:
10.3390/mi
croorgani
sms91020
39
Science Citation
Index Expanded,
Scopus, PubMed,
Chemical Abstracts
(ACS), EMBASE
4.926
20
32. M. Yang, Shambhunath
Bose, S. Lim, J. Seo, J.H.
Shin, Y.D. Nam, and H.
Kim
Beneficial Effects of newly
isolated Akkermansia
muciniphila strains from the
human gut on obesity and
metabolic dysregulation
Microorganisms
MDPI, Basel, Switzerland
ISSN 2076-2607; CODEN:
MICRKN
2020; 8
(9): 1413,
doi:
10.3390/mi
croorgani
sms80914
13
Science Citation
Index Expanded,
Scopus, PubMed,
Chemical Abstracts
(ACS), EMBASE
4.926
33. Shambhunath Bose, M.
A. Farah, H.C. Jung, J. H.
Lee, and Y. Kim
Molecular mechanism of
bis(maltolato)oxovanadium(IV)-
induced insulin signaling in
3T3-L1 and IM9 cells: Impact of
dexamethasone.
Journal of Molecular
Endocrinology
Society for
Endocrinology, UK
Print ISSN: 0952-5041;
Online ISSN: 1479-6813
2007;
38(6): 627-
649
Science Citation
Index, Scopus,
BIOSIS, Chemical
Abstracts, PubMed,
4.869
34. J. Cho, C. Park, Y. M. Lee,
S. Kim, Shambhunath
Bose, M. Choi, A. S.
Neuroprotective and antioxidant
effects of novel benzofuran-2-
carboxamide derivatives.
Biomolecules &
Therapeutics
2015;
23(3): 275-
282
Science Citation
Index Expanded,
Scopus, PubMed,
4.231
Kumar, J. K Jung, and H.
S. Lee
The Korean Society of
Applied Pharmacology,
South Korea
Online ISSN: 2005-4483
Print ISSN: 1976-9148
PubMed Central
35. S. W. Hong, J. W. Yoo, J.
H. Park, Shambhunath
Bose, H. J. Kim, S. Kim,
and D. K. Lee
(Clinical Investigation)
Gene expression profiling of
Bangpungtongseong-san
(Bofutsushosan) and
Bangkihwangki-tang (Boiogito)
administered individuals.
BioChip Journal
Springer Nature
Switzerland AG
ISSN: 1976-0280 (Print);
2092-7843 (Online)
2012; 6(2):
139-148
Science Citation
Index Expanded,
Scopus, BIOSIS,
Biological Abstracts,
CAS
4.229
36. S. W. Hong, J. W. Yoo, H.
Kim, S. Jeon,
Shambhunath Bose, S.
Kim, and D.K. Lee
(Clinical Investigation)
Evaluation of RNA amplification
method for high-density DNA
microarray.
BioChip Journal
Springer Nature
Switzerland AG
ISSN: 1976-0280 (Print);
2092-7843 (Online)
2010; 4(1):
70-74
Science Citation
Index Expanded,
Scopus, BIOSIS,
Biological Abstracts,
CAS
4.229
21
37. J. H. Wang, Shambhunath
Bose, S. K. Lim, A.
Ansari, Y. W. Chin, H. S.
Choi, and H. Kim
Houttuynia cordata facilitates
metformin on ameliorating
insulin resistance associated
with gut microbiota alteration in
OLETF rats.
Genes (Basel)
MDPI, Basel,
Switzerland
ISSN: 2073-4425;
CODEN: GENEG9
2017;
8(10): 239
Science Citation
Index Expanded,
Scopus, Biological
Abstracts, BIOSIS
Current Contents
4.141
38. M. A. Farah,
Shambhunath Bose, J. H.
Lee, H. C. Jung, and Y.
Kim
Analysis of glycated insulin by
MALDI-TOF mass
spectrometry.
Biochimica et
Biophysica Acta
(General Subjects)
Elsevier B.V.,
The Netherlands
ISSN: 0304-4165
2005;
1725(3):
269-282
Science Citation
Index, Scopus,
PubMed, Current
Contents, EMBASE
4.117
39. H. Zhao, R. Sood, A. Jutila,
Shambhunath Bose, G.
Fimland, J. Nissen-Meyer,
and P.K. Kinnunen
Interaction of the antimicrobial
peptide pheromone Plantaricin
A with model membranes:
Implications for a novel
mechanism of action.
Biochimica et
Biophysica Acta
(Biomembranes)
Elsevier B.V.,
The Netherlands
ISSN: 0005-2736
2006;
1758(9):
1461-1474
Science Citation
Index, Scopus,
PubMed, Current
Contents, EMBASE,
Chemical Abstracts
4.019
40. Shambhunath Bose, S.
Kim, Y. Oh, Md.
Moniruzzaman, G. Lee,
Effect of CCL2 on BV2
microglial cell migration:
Cytokine
Elsevier B.V.,
The Netherlands
2016; 81:
39-49
Science Citation
Index, Scopus,
PubMed, Current
3.926
and J. Cho Involvement of probable
signaling pathways.
ISSN: 1043-4666 Contents, EMBASE,
Chemical Abstracts
41. . B. Lee*, Shambhunath
Bose*, S. H. Ahn, B. H.
Son, B. S. Ko, H. J. Kim, Il.
Y. Chung, J. Kim, W. Lee,
M.-S. Ko, K. Lee, S.
Chang, H. S. Park, J. W.
Lee, D. C. Kim (*These
authors contributed
equally to this work)
(Clinical Investigation)
Breast cancer diagnosis by
analysis of serum N-glycans
using MALDI-TOF mass
spectroscopy.
PLoS One
Public Library of Science
(PLOS), USA
ISSN: 1932-6203
2020;
15(4):
e0231004
Science Citation
Index Expanded,
Scopus, PubMed,
EMBASE, CAS,
MEDLINE, Web of
Science
3.752
22
42. K. Han, Shambhunath
Bose, J. H. Wang, S. K.
Lim, Y. W. Chin, Y. M. Kim,
H. S. Choi, and H. Kim
In vivo therapeutic effect of
combination treatment with
metformin and Scutellaria
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