research fellow
Resume:
Curriculum Vitae
Moushumi Ghosh Roy, PhD
Patiya,Chittagong Bangladesh
Contact No: +88-017********
Email : ************@******.**.**, **********@*****.*** Education
**** – 2024 PhD in Vaccinology & Applied Immunology, Lovely Professional University, Punjab, India. Dissertation: “Mimicking natural anti-DENV antibody response in mice model using dengue envelope protein domain 3”
2008 - 2010 MS in Biotechnology and Genetic Engineering, University of Development Alternate (UODA), Dhaka, Bangladesh.
Dissertation: “Pharmacological Study on Anti-diabetic (hypoglycemic) effect of leaves, fruits and seeds of Tamarindus Indica in Swiss Albino Mice” 2003 - 2008 B.Sc in Biochemistry and Biotechnology, University of Science and Technology, Chittagong
(USTC) Bangladesh.
Dissertation: “Studies on Prevalence, Biochemical tests and Diagnostic Tools of Diabetes Mellitus: Net 2 Gene Polymorphism and Hepatitis”
Professional Positions and Research Training
2025- Cont. Research fellow, Department of Biochemistry, City University of New York, “studying the effect of different bioactive nanofibers loaded wound healing gauze” Mentor: Dr. Krishnaswami Raja.
2024- Cont. Lecturer, Department of Pharmacy, BGC Trust University Bangladesh, “Since 2024, 2012-2024 Lab Professor, Department of Pharmacy, BGC Trust University Bangladesh, “Since 2012, I have been supervising ( all Lab class) B. Pharm students at the Department of Pharmacy, BGC Trust University Bangladesh”
2010 – 2011
2009-2010
2008-2009
2008-2009
Diabetes Educator, Cox’s Bazar Diabetes Hospital Bangladesh, I have been teaching the diabetic patient about their nutrition and life style. Training program, BIRDEM, “Improving Diabetes Management in Bangladesh through Diabetes Educators”.
Training Program, BIRDEM and BISH, laboratories of Biochemistry, Microbiology, Immunology, Hematology & Pathology, Molecular biology and Histopathology Training Program, BCSIR, “ Ongoing research projects such as Fruits Processing & Preservation, Cereal Technology, Oil seeds & Legumes Technology and Food Toxicology” Publications
Complete list of published articles:
Dr. Moushumi Ghosh Roy - Google Scholar
Total: 05 first/ author: 4
1. Moushumi Ghosh Roy, Kutub Uddin, Din Islam, M. Monirul Islam, Anjuvan Singh, “Secondary DENV Infections Along with Concurrent Multiple DENV Serotypes in a Single Dengue Session Contributing to Dengue Severity in Chittagong Bangladesh” Journal of Survey in Fisheries Sciences, Page 627-642,2023. 2. Moushumi Ghosh Roy, Mohammad Monirul Islam and Anjuvan Singh, “Prevalence of dengue virus, their infection, diagnosis and challenges,” Journal of Applied Biology & Biotechnology, Page 1-8, 2023. 3. Moushumi Ghosh Roy, Kutub Uddin, Din Islam, Anjuvan Singh and Mohammad Monirul Islam, “All four dengue virus serotypes co-circulate in concurrent dengue infections in a single dengue session in Chittagong, Bangladesh”, Bioresearch Communications, page 1041-1048, 2022.
4. Moushumi Ghosh Roy, Shanz Rahman, Mahmuda Munmun, Nasima Sharmin, Ziaul Hasan, Abdullah Al Mamun, Afsana Khatun and Mohammed Rahmatullah, “Evaluation of Anti-hyperglycemic potential Extract of Tamarindus Indica L.(Fabaceae) Fruits and seeds in Glucose-induced Hyperglycemic mice”, American Eurasian Network for Scientific Information, page 159-162, 2010.
5.Md. Din Islam, Tahmina Sharmin, Imrul Hassan Tipo, Antara Saha, Sanjida Yesmin, Moushumi Ghosh Roy, Subbaiam Brindha, Yutaka Kuroda, M. Monirul Islam, “The immunogenicity of DENV1-4 ED3s strongly Differ despite their almost identical three dimensional structures and high sequence similarities”, International Journal of Molecular Sciences, page 08-11,2023.
Research Presentations in conferences:
I have delivered three oral presentation and three poster presentations at various academic conferences 1. Oral presentation on the topic “Secondary DENV infections along with concurrent multiple DENV serotypes in a single dengue session contributing to dengue severity in Chittagong, Bangladesh” at the BSBMB-SABC-OMC International conference held on 03-05 February 2023 at Nabab Nawab Ali Chowdhury Senate Bhaban. University of Dhaka.
2. Oral presentation on the topic, “Serotype-specific clinical manifestations of dengue in Chittagong, Bangladesh” at the International Conference on Biomacromolecules and Cellular Interface (ICBCI-2021) held on 9-10 January 2021 at Dr. B.R Ambedkar National Institute of Technology, Jalandar-144011, Punjab, India. 3. Oral presentation on the topic, “2019 Dengue Outbreak in Chittagong: Seroprevalence and natural anti-dengue antibody responses” at the Sixth Conference of Bangladesh Crystallographic Association held on 15-16 January 2021.
4. Poster presentation on the topic, “Prevalence of Dengue Virus, Their Infection, Diagnosis and Challenges” at International Conference on Sustainability: Life on Earth 2021 (ICSLOE 2021) held on 17-18 December 2021 organized by Department of Botany and Zoology, School of Bio-engineering and Biosciences, and Institute of Forest Productivity, Ranchi, Jharkhand at Lovely Professional University, Punjab. 5. Poster presentation on the topic, “Anti-dengue antibody responses in concurrent dengue infections” at the 1st research symposium organized by the Institutional Quality Assurance Cell (IQAC) of the University of Chittagong Bangladesh held on 24 March 2022.
6. Poster presentation on the topic, “Four Different DENV ED3s Generated Different T- cell Memory in Artificial Immunization in Mice Model” at the 1st Jamal Nazrul Islam National Conference for young researchers organized by University .of Chittagong Bangladesh held on 21 May 2022. Research Experiences
Current Research (2025 to Continued)
City University of New York University, USA (February 2025 to date)
"Our lab focuses on the mechanisms of healing utilizing Solution Blow Spinning (SBS), a relatively novel technique. We assess the cytotoxicity, curcumin release, wound healing efficacy, and antimicrobial properties of turmeric-loaded PLGA microfiber mats through both in vitro and in vivo studies." Lovely Professional University, India; Ph.D. Research (May 2019 to April 2024)
Design and construct different sets of viral vectored Dengue vaccine candidates.
Plasmids constructs encoding ED3s, Transformation into E. coli.
DENV ED3 Expression and Purification.
Investigation of natural dengue infection
Counting of Platelet, RBC and WBC following dengue infection
DENV Serotyping by ELISA; Natural anti-DENV IgM and anti-DENV IgG responses.
Correlation of infecting DENV serotype and dengue disease severity
Mimicking natural DENV infections in mice model
Immunization with ED3s of DENV1~4 in mice (Primary, Secondary, Tertiary, Quaternary and Concurrent Multiple)
Sample collection through tail-bleeding.
Anti-ED3 antibody determination by ELISA.
Investigation of the T cell memory status following DENV ED3 immunization in mice by flow-cytometry
Establishing the correlation between anti-DENV responses in natural DENV infections and anti-ED3 responses in mice model and proposing a model system for future dengue research University of Development Alternate (UODA),Bangladesh MS Thesis (Jan 2009 – July 2010)
Investigation of the pharmacological properties of various indigenous medicinal plant by preparing the crude extracts.
Identification of the pharmacological activities by correlating with wet lab and dry lab analysis.
In silico characterization of the isolated compounds of the medicinal plants using computer- aided drug discovery.
Anti-diabetic effect of Tamarindus Indica leaves, fruits and seeds on the glucose concentrations of swiss albino mice
University of Science and Technology Chittagong (USTC) B.Sc (Hons) Jun 2003 – Jan 2008
Net2 Gene Polymorphism form diabetic infected patients
Biochemical tests and Diagnostic Tools of Diabetes Mellitus: Hepatitis”
.
Technical Expertise
Biochemistry & molecular biology : Molecular biology & cloning (DNA and RNA extraction, cDNA preparation, qualitative/quantitative real-time PCR, RT-PCR, qRT-PCR, gel electrophoresis, SDS-PAGE); Protein expression and purification; Gel permeation Chramatography(GPC), Solution Blow Spinning (SBS),. Immunology: In vivo immunization; Immunological methods to identify and quantify expression of proteins; antibody ELISA, Functional immunological assays, Primary cell culture. Cellular Biology: Mammalian cell culture, Flow cytometry, Cell cycle assay, Protein extraction, RNA isolation and purification.
Microbiology: Microscopy; Bacterial staining, Plating methods (streak/spread/pour); Media/buffer preparation. Phytochemistry/other: Extraction methods and tests including methanolic, ethanolic; Cold and hot extractions; Brine shrimp lethality testing.
Animal Husbandry: Mouse injections (intraperitoneal, intramuscular), blood collection. Statistics: General statistical analysis, including Student’s t-test. Software: Microsoft Word, Excel, PowerPoint.
Communication skill: Presentation & publication of scientific data, Coordination of interdisciplinary projects, collaborating with cross-functional colleagues to develop and test research ideas, Supporting the career development of colleagues and team members.
Non-technical Expertise
• Strong laboratory management skills, ability to train and supervise graduate/under graduate students, staff and junior lab personnel.
• Ability to work independently
• Experience on manuscript preparation
• Experience on planning, development and implementation of laboratory requirements
• Experience on purchasing laboratory reagent and instrument and above all excellent written and oral communication skills.
Reference:
Prof. Dr. Anjuvan Singh
Department of Biotechnology,
Lovely Professional University,
Phagwara - 144 011, Punjab, India.
E- mail:*******.*****@***.**.**
Mobile:+917*********
Dr. Nurul Absar,
Professor and Head,
Department of Biochemistry & Biotechnology,
University of Science & Technology Chittagong,
Foy’s Lake, Chittagong-4202, Bangladesh
e-mail: **********@*****.***
Cell: 880-1717796123
Prof. Dr. Tapashi Ghosh Roy
Professor, Department of Chemistry
University of Chittagong
E-mail: **********@**.**.**
Mobile: +88-018********, +88-017********
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