Operations Manager Laboratory

Zainab Mahmod

********@*****.*** 857-***-**** Hudson, MA

SUMMARY

Experienced Laboratory Operations Manager with a strong background in research lab management and implementing advanced laboratory systems. Proven in transitioning to modern facilities, optimizing budgets, and enforcing safety and regulatory standards. Skilled in daily operations, inventory management, and equipment maintenance, with expertise in GMP and GDP guidelines. Committed to operational excellence and effective team collaboration.

EXPERIENCE

Ocular Therapeutix, Bedford, MA

Laboratory Operations Manager August 2022- August 2024

-Orchestrated the design and execution of the transition into a state-of-the-art 4,400 ft R&D laboratory, collaborating closely with managers, scientists, and facilities personnel to develop an optimal lab layout for efficient equipment placement, workspace allocation, and personnel flow.

-Leveraged negotiation skills to secure competitive pricing from vendors for essential equipment and furniture, optimizing budget utilization for the lab extension.

-Assumed responsibility for the safety protocols and daily operations across four distinct laboratory spaces, ensuring adherence to stringent safety standards, including the provision and enforcement of appropriate PPE practices.

-Proactively managed a comprehensive inventory of over 50 chemicals and consumables, guaranteeing seamless continuity of daily laboratory activities.

-Implemented and enforced proper protocols for the disposal of both non-hazardous and hazardous waste streams, maintaining a safe and compliant working environment in accordance with regulatory guidelines.

-Coordinated closely with facilities management and external vendors to schedule and oversee critical lab activities, including preventive maintenance, calibration, and utilities management, ensuring minimal disruptions to ongoing operations.

-Apply GMP and GDP guidelines to all activities

-Maintain an environmentally controlled area (clean room) as required

-Keep manufacturing areas orderly and clean according to associated SOPs

-Coordinates routine cleaning of the lab space

-Troubleshoot issues as they arise related to equipment and/or manufacturing processes

-Request documentation and reconcile QA comments related to executed documentation

Brigham and Women's Hospital, Boston, MA

Research Lab Manager- Dr. Raphael Bueno Lab Dec 2019 – August 2022

-Supervise the operation and ensure smooth functioning of the laboratory

-Conduct isolation of PBMCs and plasma from fresh whole blood for clinical trials and research experiments

-Conduct extraction and quality control of RNA from whole blood and tissue

-Collect pleural effusion and pleural cells from patients with malignant pleural mesothelioma for clinical trials and research experiments

-Organize and classify large collections of samples (DNA, RNA, protein, paraffin blocks) from lung cancer and mesothelioma tumors

-Responsible of cell line propagation for the entire laboratory

-Responsible of samples inventory, samples management and freezers temperature monitoring system (SmartSense and Alarm Central) and routine refrigerator and freezer defrosting

-Support Environmental Health and Safety (EHS) program

-Conduct regular safety audits and inspections.

-Coordinate services related to glass wash, laboratory supplies, biohazard chemical waste, and chemical stockroom

-Coordinate activities related to instrument calibration, maintenance, repair, ordering parts and

replacing parts with maintenance and engineering

Broad Institute of MIT & Harvard, Cambridge, MA

Process Technician May 2014 – Dec 2019

-Maintained freezer organization and freezer database

-Maintained and tracked lab chemical and reagent inventories

-Maintained basic GMP and carried out two CAPA for the Sequencers

-Assisted with bench level molecular biology

-Performed checking data quality, loading flowcells on Illumina Sequencers (HiSeq X, HO 2000V4, RR 2500, Novaseq) as well as troubleshooting

-Participated in CLIA certified workflow(s)

-Expert in providing maintenance, loading and troubleshooting of cBot Units

Department of Pharmacology, Boston University School of Medicine, Boston, MA

Lab Technician Intern Feb 2013 – May 2014

-Assisted with in vivo electrophysiology studies by building the multichannel microdrives used to identify new drugs for neurological and psychiatric disorders.

-Worked on the repair and maintenance of high throughput in vitro electrophysiology apparatus.

-Preformed aseptic surgical extraction of oocytes from Xenopus Laevis frogs and injection with RNA for chosen receptors

-Assisted with surgery and extraction of embryonic neuronal tissue from pregnant rats to maintain primary cultures of hippocampal neurons

-Assisted with aseptic stereotaxic surgery for cranial implant of microdrives in rats

-Trained undergraduate students

SKILLS

Lab Skills: Equipment maintenance, oral communication, waste management, inventory management, basic troubleshooting skills on process equipment, problem solving, strategic thinking, maintaining specimens and freezers, GMP/GDP knowledge, operational excellence operating on sequencer and cBot machines, reagent preparation, buffer preparation, dilutions, light and inverted microscopy, maintenance of mammalian cell cultures (aseptic technique, passaging, freezing)

Courses: Medical Terminology, Essential Methods in Biotechnology, Business of Biotech, Cell Culture Techniques, Seminars in Critical Thinking and Workplace Skills

Awards:

- Obtained the Queenan Memorial Award for academic excellence at Boston University May 2013

- Received A Spotlight Award for the Research Brigham Employees June 2022

Certificates: RCRA & DOT

EDUCATION

BioScience Academy, Boston University School of Medicine, Metropolitan College

Certificate in Applied Biotechnology May, 2013

University of Baghdad, College of Engineering

Bachelor of Science Degree in Civil Engineering May, 1985

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