Weidong Cao

***** ******** ***, ***** *******, MD 20878, 301-***-****. adxup6@r.postjobfree.com

SUMMARY

Extensive background in field of bioanalysis including molecular assays design, nucleic acids isolation, Library preparation for NGS sequencing, rPCR, ddPCR, NGS sequencing, Immunoassay assay, HPLC-MS and capillary electrophoresis separation, bioconjugation and nanoparticles fabrication.

WORKING EXPERIENCE

Manager of QC/QA Darui Biotechnology, 2021.03-2023.3

Oversaw COVID-19 molecular diagnostic assay kit production to assure manufacturing process meet the regulation requirement and all reagents and components meet the desired quality.

Developed bioanalytical methods to test the quality of the COVID-19 kit production.

improved the sequencing accuracy on Ion Torrent.

Scientist Ontera Bio at Santa Cruz 2018.10 – 2021.02

1. Designed assays for GMO product identification and Zika disease detection with nanopore sequencing.

2. Developed methods for primer-PEG tag synthesis, purification and qualification with HPLC-MS and rPCR.

3. Invented fast PCR using photonic PCR technology. Invented 5 minutes microfluidic PCR technology.

Senior scientist Canon U.S. Lifesciences, 2006.10 – 2018.09

1. Developed capillary electrophoresis separation method for identifying PCR products collected from a microfluidic PCR chip.

2. Developed a series of molecular assays for genetic disease and delivered it to the manufacture group.

3. Developed molecular assays for detecting exosomes in urine sample.

4. DNA methylation analysis with NGS sequencing for lung cancer mutation test.

5. Collaborated with university of Maryland for developing a DNA extraction and purification kit for the next generation molecular diagnostic platform.

6. Developed antibody coated nanoparticles for POCT applications.

EDUCATION

PhD in chemistry, University of Chinese Academy of Sciences. 2002

Postdoctoral, electrochemiluminescence(ECL) project. University of Texas at Austin 2003-2004

Postdoctoral, capillary electrophoresis for DNA and protein separation. University of Virginia 2004-2006

HONOR

Canon USA president spirit award, 2008

SELECTED PAPERS AND PATENTS

1.Automated Microfluidic Platform for Serial Polymerase Chain Reaction and High-Resolution Melting Analysis. Weidong Cao, Brian Bean, Scott Corey, Johnathan Stuart Coursey, Kenton C Hasson, Hiroshi Inoue, Taisuke Isano, Sami Kanderian, Ben C Lane, Hongye Liang, Brian R. Murphy, Greg J Owen, Nobuhiko Shinoda, Shulin Zeng, Ivor T. Knight.Journal of laboratory automation, March,2015

2.Quenching of the Electrochemiluminescence of Tris(2,2‘-bipyridine)ruthenium(II) by Ferrocene and Its Potential Application to Quantitative DNA Detection. Weidong Cao, Jerome P. Ferrance, James Demas and James P. Landers.J. Am. Chem. Soc., 2006, 128 (23), pp 7572–7578

3. Single-step dna preparation for polymerase chain reaction using magnetic chitosan microparticles Publication number: 201********

4. System and method for serial processing of multiple nucleic acid assays Patent number: 9114399

5. Photonic polymerase chain reaction and temperature sensing. US 63/000,143

Contact this candidate