ISAAC UZOMA ASUZU adqxtf@r.postjobfree.com • 434-***-****

Higher Education Management

Drug Development Techniques Maintenance of Transgenic Mice Colony

Resourceful professional with several years of teaching and research experience. Serves as a Fellow of the Nigerian Academy of Science (FAS). Recognized for work that includes collaborating with small and medium companies involved in drug development from natural products. Successfully managed several research grants from the International Foundation for Science (IFS), African Bioscience network, Wellcome trust, Third World Academy of Science, and World Bank. Qualified veterinarian specializing in veterinary pharmacology and toxicology. Active Fellow of the College of Veterinary Surgeons, Nigeria (FCVSN). Acknowledged as an experienced administrator who has served as head of department, dean of faculty, and vice-chancellor of a university. Provided stellar leadership while managing staff and students. Highly skilled in in-vitro and in vivo techniques, tissue culture, maintenance of transgenic mice colony, sperm / embryo cryopreservation, and PCR techniques. Known for published work and over 130 journal articles.

CORE COMPETENCIES / AREAS OF EXPERTISE

Genetic Engineering Administration Management Research Accounting Budgets / Forecast Report Writing

Project Designs Staff Management Laboratory Management Academic Leadership Guideline Development

In Vitro and In Vivo Pharmacological Techniques Drug Development Techniques Training / Development

CAREER EXPERIENCE

Laboratory Specialist Present

Genetically Engineered Murine Model (GEMM)

Serve as the laboratory specialist; charged with overseeing and identifying key research for the core of the school of medicine, University of Virginia, Charlottesville.

Executes genetic engineering (from transgenesis to genome editing), utilize CRISPR technology, gene editing strategies, and complete project designs. Ensure maintenance of transgenic mice colony, sperm cryopreservation / rederivation, embryo cryopreservation, rederivation.

Successfully use PCR to determine sex and genotype, agarose gel electrophoresis.

Vice-Chancellor, Federal University Oye-Ekiti 2013 – 2016

Managed administration of the university and submitted regular reports to the Federal Ministry of Education. Presided over the university Senate, which was responsible for all academic matters affecting students and staff.

Functioned as the chief accounting officer of the university and defended the annual budget of the university before the National Assembly.

Acted as chairman of the appointment and promotions committee; responsible for the appointment of new staff and promotion of staff on regular appointment.

Executed various duties as Vice-Chancellor, oversaw security of both staff and students on campus.

Deputy Vice-Chancellor Academic, University of Nigeria, Nsukka 2009 – 2013

Assisted the Vice-Chancellor in the day-to-day activities of the university. Directed university affairs when the Vice-Chancellor was on official assignment outside the university.

Led all academic matters and submitted reports to the Vice-Chancellor. Successfully chaired several university standing- committees and submitted reports of such meetings to the Vice-Chancellor.

Dean, Faculty of Veterinary Medicine, University of Nigeria, Nsukka 2002 – 2004

Chaired all faculty board meetings; oversaw promotion of staff for and recommended them to the University appointment / promotions committee.

Represented faculty in the committee of deans meetings and served as representative of the faculty on the veterinary council of Nigeria board.

Charged with submitting reports of activities in the faculty to the vice-chancellor.

ADDITIONAL NOTABLE EXPERIENCE

Associate Dean, Faculty of Veterinary Medicine, University of Nigeria, Nsukka

Assisted the dean of faculty and oversaw its activities when he was not available. Prepared and presented reports of activities as the Faculty to the Dean.

Head, Department of Veterinary Physiology & Pharmacology, University of Nigeria, Nsukka

Provided academic and administrative leadership and served as chairman of postgraduate committee in the department. Acted as Chairman of curriculum committee where new programs were introduced and old programs modified. Submitted reports of departmental meetings to the dean.

Professor, Department of Veterinary Physiology & Pharmacology, University of Nigeria, Nsukka

Charged with teaching postgraduate courses and supervising postgraduate projects. Taught pharmacology and toxicology courses to both DVM and M.Sc. students. Participated in active research and preparation of research grant proposals and provided academic leadership to the younger lecturers in the department.

Senior Lecturer, Department of Veterinary Physiology & Pharmacology, University of Nigeria, Nsukka

Tasked with teaching and research and played an administrative role when assigned by the head of department.

Lecturer I, Department of Veterinary Physiology & Pharmacology, University of Nigeria, Nsukka

Educated DVM students on various aspects of Veterinary Pharmacology and Toxicology. Provided exceptional support while also engaged in part-time PhD program.

Prior Experience: Lecturer II, Department of Veterinary Physiology & Pharmacology, University of Nigeria, Nsukka; Visiting Research Professor, Department of Physiology & Pharmacology, University of Strathclyde, Glasgow, UK; Academic Visitor, Department of Physiology & Pharmacology, University of Strathclyde Glasgow, UK; Visiting Research Scientist, Department of Biomedical Sciences, University of Trieste, Italy; Postdoctoral Fellow, Phytochemistry Research Laboratory, University of Strathclyde, Glasgow, UK

EDUCATION & PROFESSIONAL DEVELOPMENT

Ph.D., Veterinary Pharmacology & Toxicology, University of Nigeria, Nsukka

Received the Vice-Chancellor’s research prize for the best PhD dissertation

M.Sc., Veterinary Pharmacology, University of Nigeria, Nsukka

Passed courses in advanced pharmacology & toxicology. Course work constituted 30% and dissertation 70%.

DVM, University of Nigeria, Nsukka.

Degree was unclassified. Emerged within the top 5% of the class.

Cross-Section of Publications

Omoja, S.O., Daniel-Igwe, G., Ejiofor,E., Mbakwe, C.C., Okeke, S.U., Ezeja, M.I., Omeh, Y.U. and Asuzu, I.U. (2019) Hypolipidemic, hepatoprotective, nephroprotective and anti-lipid peroxidation properties of a methanol extract of Paulinia pinnata root-bark in alloxan-induced hyperglycemic rats. Current Issues in Pharmacy and Medical Sciences 32(3) 125-129.

Udeh, N.E., Anaga, A.O. and Asuzu, I.U. (2018) Protective effect of Gnetum africanum methanol leaf extract on pancreatic islet cells in rats. Comparative Clinical Pathol., 27 (3), 1-6.

Aba, P.E. and Asuzu, I.U. (2016). 1H-proton NMR spectra of anti-hyperglycemia triterpenoid isolated from Cussonia arborea. J. Natural Products 9, 5-13.

Aba, P.E. and Asuzu, I.U. (2015). Effects of administration of methanol root bark extract of Cussonia arborea on serum biochemical markers of kidney damage and renal histomorphology of alloxan-induced diabetic rats. Journal of Advances in Medical and Pharmaceutical Sciences. 5 (2), 1-9.

Omoja, V.U., Asuzu, I.U. and Anika, S.M. (2015). Assessment of the hepatic and renal effects of sub-chronic administration of sub-lethal doses of amitraz/xylene in albino Wister rats. Comparative Clinical Pathology. 10.1007/s00580-015-2170-4. 1-7.

Onakpa, M.M., Zhao, M., Godecke T., Chen, W., Che, C., Santarsiero, B.D. and Asuzu, I.U. (2014) Cytotoxic (9 BH)-Pimarane and (9BH)-17-Norpimarane Diterpenes from the tuber of Icacina trichantha. Chemistry and Biodiversity. 11, 1914-1922.

Ezeja, M.I., Anaga, A.O. and Asuzu, I.U. (2014) Antidiabetic, antilipidemic and antioxidant activities of Gouania longipetala methanol leaf extract in alloxan-induced diabetic rats. Pharmaceutical Biology. DOI: 10.3109/13880.2014.935864. 1-10.

Ode J.O. and Asuzu, I.U. (2014) Luteolin isolate from the methanol exract identified as the single-carbon compound responsible for broad antiulcer activities of Cassia singueana leaves. IOSR Journal of Pharmacy. (e)-ISSN: 2250-3013. 4, Issue 10, 17-23.

Onakpa, M.M., Godecke, T., Zhao, M., Santarsiero, B.D., Asuzu, I.U. and Che, C.T. (2013). 9B primarane diterpenes from the tuber of Icacina trichantha. Planta Medica 79 (10), DOI: 1055/s-003*-*******.

Ogbu, S.A., Agwu, K.K. and Asuzu, I.U. (2013) Effect of Gongronema latifolium on gastric emptying in healthy dogs. World Journal of Gastroenterology. 19, 897-902.

Ode, O.J., Asuzu, I.U. and Ajayi, I.E. (2011) Bioassay-guided fractionation of the crude methanol extract of Cassia singueana leaves. Journal of Advanced Scientific Research 2, 81-86.

Igboeli, O.O. and Asuzu, I.U. (2010) Sub-chronic toxicity of Senilia senilis hepatopancreas. Bulletin of Evironmental Contamination and Toxicology 84: 657-661.

Ode, O.J. and Asuzu, I.U. {2006} The anti-snake venom activities of the methanolic extract of the bulb of Crinum jagus (Amaryllidaceae}. Toxicon 48, 331-342.

Asuzu, I.U. and Harvey, A.L. (2003) The antisnake venom activities of Parkia biglobosa (Mimosaceae) stem extract. Toxicon. 42, 763-768.

Asuzu, I.U., Gray, A.I. and Waterman, P.G. (1999) The anthelmintic activity of D-3- O-methylchiroinositol isolated from Piliostigma thonningii stem bark extract. Fitoterapia. 70, 77.

Asuzu, I.U., Sossa, S. and Della Loggia, R. (1999) The anti-inflammatory activity of the extracts of Icacina trichantha tuber. Phytomedicine. 6, 267-272.

Njoku, C.J., Hopp, D.C, Alali, F., Asuzu, I.U. and MacLaughlin, J.L. (1997) Dihydroguaiaretic acid, a bioactive component of the stem bark of Pycnanthus angolensis (Myristicaceae). Planta Medica. 63, 580-581.

Odika, I.E., Asuzu, I.U. and Anika, S.M. (1995) The effects of hyperosmolar agents lithium chloride and sucrose on the brain concentration of diminazene aceturate in rats. Acta Tropica. 60, 119-125.

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