Gary Angles

US citizen, Bilingual

**** ******* ** ***

San Diego, CA 92111

505-***-****

adn01w@r.postjobfree.com

adn01w@r.postjobfree.com

Chemistry, biochemistry & biophysics with molecular dynamics

Molecular dynamics, AMBER, Gromacs, Gaussian G16; Cell Cultures, HPLC, Protein Separation, SDS page, Western Blot; c++, c#, python, php, CUDA, Machine learning. Speak Spanish, English, Incan Languages, Beginner French; Licensed soccer coach and skydiver.

Education

PHD 2019 New Mexico Institute of Mining and Technology, Socorro, NM

· Major: Chemistry, computational chemistry, with biochemistry& biophysics.

MS 2013 New Mexico Highlands University, Las Vegas, NM

· Major: Chemistry, with biochemistry, organic, inorganic synthesis, and crystallography.

GRADUATE STUDIES 2005-2007 University of New Mexico, Albuquerque, NM

· Area of study: Graduate program chemical engineering.

BS 1997 New Mexico Highlands University

· Major: Chemistry, with computer science and software engineering.

Experience

Nanome Inc, San Diego, CA Jan 2021 – Mar 2021 Applications Scientist (Contract)

· Contributed to the testing and development of virtual reality (VR) applications.

· Assisted biopharma clients customize, troubleshoot the VR software to their research.

· Generated leads & sales in scientific networks, and biopharma.

UCSD, San Diego, CA Nov 2019 – Nov 2020 Postdoc

· Developed & achieved prediction of protein effects of biomaterials mechanical properties.

· Achieved and established methods for biomaterial properties measurement.

Los Alamos National Labs, Los Alamos, NM Feb 2018 – Nov 2019 Research Assistant

· Achieved theoretical prediction to design new explosive triggering compounds, properties, and yields.

· Achieved, with a team, the development of IED & chemical weapons detection methods and devices.

New Mexico Institute of Mining and Technology, Socorro, NM Jan 2014 – Sep 2019 Research Associate

· Developed a simplified method to characterize diffusion permeation through biomaterials macro models.

· Proposed and achieved corrections needed to EPR measurement methods that were unquestioned.

New Mexico Highlands University, Las Vegas, NM Jan 2011 – May 2013 Research Assistant

· Biochemistry: Worked on cell cultures, protein expression, HPLC.

· X-ray diffractometry of small molecules and proteins.

· Synthesis of organic & inorganic compounds and characterization.

Publications

· Romanov AS, Angles GF, Antipin MY, Timofeeva TV, Acta Cryst. (2012) C68, m69-m72.

· Mohapatra SK, Angles G, Marder SR, J of Organometallic Chem. (2012) Volumes 706–707, 140–143.

· Romanov AS, Angles GF, Timofeeva TV, Corsini M, Fabrizi de Biani F, CrystEngComm (2015) 17, 7564-7573.

· Angles G, Dotson R, Bueche K, Pias SC, Advances in experimental medicine and biology, ISOTT (2016) 977, 9-14.

· Dotson R, Smith C, Bueche K, Angles G, Pias S, Influence of cholesterol on the oxygen permeability of membranes: insight from atomistic simulations, Biophysical Journal (2017) 112, June 6, 2336-2347.

· Nguyen TD, Veauthier JM, Chavez DE, Angles G, Nelson TR, Lapsheva E, Schelter EJ, Correlating Mechanical Sensitivity with Spin Transition in the Explosive Spin Crossover Complex [Fe(Htrz)3]n[ClO4]2n, JACS (2019)142, 10, 4842-4852

· Kaseman D, Nelson TR, Angles G, et.al., Chemical Analysis of Fluorobenzenes via Multinuclear Detection in the Strong Heteronuclear J-Coupling Regime, Applied Sciences (2020) 10, 11, 3836.

· Kaseman D, Nelson TR, Angles G et.al., J-Coupled Spectroscopy prediction of nerve gas agents at Earth’s Magnetic Field, Journal of Magnetic Resonance (2020) Submitted.

· Angles G, Pias S, Markov chain Monte Carlo solution for steady state permeation through lipid bilayers, Biophysical Journal (2020) Under review.

· Angles G, Pias S, Atomistic simulations modify interpretation of spin-label oximetry data. Part 1: intensified water–lipid interfacial resistances, Biophysical Journal (2021) Submitted.

· Angles G, Pias S, Discerning Membrane Steady-State Oxygen Flux by Monte Carlo Markov Chain Modeling, Advances in Experimental Medicine and Biology (2021) 126*-***-***.

· Qi Wang, Dotson R, Angles G, Pias S, 3 Simulation Study of Breast Cancer Lipid Changes Affecting Membrane Oxygen Permeability: Effects of Chain Length and Cholesterol, Oxygen Transport to Tissue XLII (2021) 1269, 15.

Presentations

· Angles G, Romanov AS, Timofeeva TV, “Synthesis, Characterization and Structures of Metallocene compounds” American Crystallographic Association in Boston, MA. July 28, 2012.

· Angles G, Pias SC, "Cross Validation of simulation and EPR oximetry approaches: membrane cholesterol reduces oxygen flux" NM IMBRE biotechnology annual meeting, Santa Fe, NM March, 2015; and at Biophysical Society 60th annual meeting, Los Angeles, CA. February 27, 2016.

· Angles G, Pias SC, "Journey to the center of a cell membrane: cavities that propel diffusion; cavity analysis of cellular membranes" NM IMBRE biotechnology annual meeting, Santa Fe, NM March, 2016.

· Angles G, Pias SC, “Lower than Expected Membrane Permeability to Oxygen, Especially When Cholesterol Content Is High” International society of oxygen transport to tissue (ISOTT), Chicago, IL July 2016.

· Angles G, Pias SC, " Molecular Simulations to Explain Experimental Oxygen Probe Behavior" NM IMBRE biotechnology annual meeting, Santa Fe, NM March, 2017.

· Angles G, Pias SC, “Tempocholine membrane probes measure oxygen in hydrophobic regions: insight from molecular” International society of oxygen transport to tissue (ISOTT), Halle/Saale, Germany, August, 2017.

· Angles G, Pias SC, “Rapid and easy calculations of oxygen transit across model cellular membranes” NM IMBRE, August, 2018.

· Angles G, Pias SC, "Cross Validation of simulation and EPR oximetry approaches: membrane cholesterol reduces oxygen flux" Biophysical Society 2019th annual meeting, Baltimore, MA. March 2, 2019.

· Angles G, Pias SC, “Discerning Membrane Steady-State Oxygen Flux by Monte Carlo

Markov Chain Modeling” International society of oxygen transport to tissue (ISOTT), Albuquerque, NM. July, 2019.

Lab experience

New Mexico Institute of Mining and Technology, Socorro, NM:

· Biochemistry Laboratory. Co-Instructor (January 2015 – May 2017).

· General Chemistry, Co-Instructor (August 2013-2016).

New Mexico Highlands University, Las Vegas, NM:

· General Chemistry Laboratory. Teaching Assistant (August 2010 – May 2012).

· Chemistry Laboratory 7, Teaching Assistant (August 2011 – December 2011).

· Instrumental Analysis Laboratory. Teaching Assistant (January 2011 – May 2011).

· Biochemistry Laboratory. Teaching Assistant (January 2011 – May 2011).

Grants/Awards

· Graduate Assistant Chemistry 21382 Research fund (2010-2012), New Mexico Highlands University, PREM LMITA, CMDITR.

· Graduate Assistant Chemistry, Teacher Assistant grant (2010-2012), New Mexico Highlands University, NSF.

· Graduate Assistant Chemistry, Teacher Assistant grant (2014-2017), New Mexico Institute of Mining and Technology.

· NIH under NIGMS grant P20GM103451 & NM INBRE.

· FASEB postdoctoral preparation institute, August 10-11, 2017 at National Harbor, MD.

· Investment club, scholarship award, spring 2018 semester.

· New Mexico Tech. Chemistry Dept. research excellence award, researcher of the year, May 2018.

· NISBRE, NIH, NIGMS seventh biennial national IDeA symposium of biomedical research excellence, (June 24-26, 2018) Wardman Park Marriott, Washington, DC.

· International Society of Oxygen Transport to Tissue, Duane Bruley award to research excellence, July 31, 2019.

Workshops

· Computational biophysics workshop, Berkeley, Energy Biosciences Building University of California Berkeley, Berkeley, CA (Klaus Schulten & Emad Tajkhorshid).

· FASEB postdoctoral preparation institute, August 10-11, 2017 at National Harbor, MD: Professional development, CV clinic, interview training, funding opportunities, networking skills.

· NISBRE, NIH, NIGMS seventh biennial national IDeA symposium of biomedical research excellence, (June 24-26, 2018) Wardman Park Marriott, Washington, DC.

· LAMMPS & computational chemistry of materials workshop sponsored by Sandia National Labs (August, 2019) Albuquerque, NM.

References

· Christopher Lee, UCSD, adn01w@r.postjobfree.com, 703-***-****

· Ali Behzadan, UCSD, adn01w@r.postjobfree.com

· Padmini Rangamani, UCSD, adn01w@r.postjobfree.com, 858-***-****

· Tammie R Nelson, Los Alamos National Labs, adn01w@r.postjobfree.com

· Sally C Pias, New Mexico Institute of Mining and Technology, adn01w@r.postjobfree.com, 575-***-****

· Arcadius V Krivoshein, University of Houston Clear lake, adn01w@r.postjobfree.com, 281-***-****

· Tatiana Timofeeva, New Mexico Highlands University, adn01w@r.postjobfree.com, 505-***-****

Additional information and skills

Nuclear Magnetic Resonance (NMR), GCMS, IR, UV-Vis, MALDI-TOF, Pipetting, dilution.

HPLC; compound and protein lyophilization.

C#, Unity

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