William N. Crowe

Phone: 336-***-****

Email: adl9vw@r.postjobfree.com

Personal Statement

I am a creative, skilled, and dedicated fifth year Biomedical Engineering PhD Candidate with experience teaching students, problem solving, and working with a variety of stakeholders. I am excited about opportunities that allow me to apply my diverse skillset to problem-solve and work with multidisciplinary teams to creatively solve engineering challenges and forward our collective goals. My experience as a team leader, instructor, and PhD candidate given me vital hands on experience with many engineering applications and systems. Available Summer 2021.

Education

PhD. Biomedical Engineering

Virginia Tech - Wake Forest University School of Biomedical Engineering and Sciences Anticipated Graduation: May 2021

B.S. Engineering Science and Mechanics

Minor: Green Engineering

Virginia Tech

May 2015

Experience

Graduate Researcher

Aug 2016 – Present Wake Forest School of Medicine Winston-Salem, NC

Gained hands on experience with Bruker 7T MRI, HIFU, IVIS Optical Imaging, and biological laboratory equipment

Trained in imaging and therapy for murine models of GBM and Brain metastasis

Conducted extensive research utilizing DLS, HPLC, NMR, and ICP-OES

Enhanced MATLAB skills through MRI image analysis and quantification

Fabricated novel lab equipment and research devices through 3D CAD and additive manufacturing

Assisted and guided younger graduate students in their research projects

Utilized orthovoltage x-ray and conventional radiation experimental methods

Developed novel nanodroplet imaging techniques using Fluorine-MRI and Ultrasound imaging

Adjunct Professor

July 2020 – May 2021 Wake Forest University Winston-Salem, NC Courses: EGR 311: Control Systems and Instrumentation (Fall 2020, Spring 2021) EGR 301A: 3D Modeling and Additive Manufacturing (Sprint 2021)

Collaborated with a teaching team to deliver educational material to students

Educated students on EE theories, instruments, and control theory

Delivered lecture material in pre-recorded, in-person, and online formats

Guided students through design and prototyping using Fusion 360 and FDM or Resin 3D printers

Hosted remote review sessions to reinforce material and accommodate students

Teaching Assistant

Aug 2018 – July 2020 Wake Forest University Winston-Salem, NC Courses: EGR 311: Control Systems and Instrumentation (Fall 2019, Spring 2020) EGR 112: Introduction to Engineering Measurement and Analysis (Spring 2019) EGR 211: Mechanics and Materials (Fall 2018)

Designed and facilitated laboratory activities for engineering students.

Collaborated with professors to structure specific lessons and course segments

Assessed student performance on a variety of tasks and assignments

Hosted office hours to assist students and expand upon lecture concepts

Undergraduate Researcher

Aug 2014 – Feb 2015 Virginia Tech Blacksburg, VA

Acquired heightened understanding of fluid mechanics including cavitation and particle dynamics

Hands-on experience with high speed imagery, instrumentation, and laboratory equipment

Featured research poster at the American Physical Society Gallery of Fluid Motion

Research Assistant

Sept 2012 – May 2015 Virginia Tech Blacksburg, VA

Operation testing and evaluation of motorcycle instrumentation (OT&E)

Supported primary investigators on sponsored contracts

Developed procedure and analyzed data for sponsored research and performed studies consistent with NHTSA and MSF standard

Undergraduate Researcher – Design and Construction of a Reduced Scale Railgun

Jan 2013 – May 2013 Virginia Tech Blacksburg, VA

Worked in multidisciplinary teams to research and design an electromagnetic launcher system for a Navy sponsored project. This was part of the NEEC (Naval Engineering Education Center) at Virginia Tech partnered with the Naval Surface Warfare Center (NSWC) Dahlgren Division.

Publications

(Submitted) Sankepalle, D., Crowe, C., Arledge, C., … & Zhao, D. (2021). Estimation of Dynamic Contrast-Enhanced MRI Kinetic Parameters in Glioblastoma Using Deep Learning.

(IEEE Transactions on medical imaging)

(Submitted) Liu, Y., Wang, L., Ali. M., Crowe, W. N., Kucera, G. L., …& Zhao, D. (2021). Intrapleural nanoparticle STING activator engages innate and adaptive immune responses to enhance anti-PD-L1 therapy for malignant pleural effusion. Nature Nanotechnology. Liu, Y., Crowe, W. N., Wang, L., Lu, Y., Petty, W. J., Habib, A. A., & Zhao, D. (2019). An inhalable nanoparticulate STING agonist synergizes with radiotherapy to confer long-term control of lung metastases. Nature communications, 10(1), 1-15. Crowe, William, et al. "MRI evaluation of the effects of whole brain radiotherapy on breast cancer brain metastasis." International journal of radiation biology 95.3 (2019): 338-346. Poulain, S., Guenoun, G., Gart, S., Crowe, W., & Jung, S. (2015). Particle motion induced by bubble cavitation. Physical review letters, 114(21), 214501.

(Patent) Zhao, D., Liu, Y. Crowe, W., “[Immunotherapeutic Cyclic Dinucleotide Nanoparticles and Methods Relating Thereto]”, U.S Provisional Patent Ser. No. 62832106, Filed: May 2019.

Notable Presentations

Crowe, W.N., Zhao, D., Decafluorobutane-based phase change contrast agent for dual ultrasound imaging and fluorine MRI. Pre-recorded oral presentation at the Biomedical Engineering Society annual meeting 2020, Online.

Crowe, W.N., Zhao, D., Development of a decafluorobutane-based phase change dual-contrast agent for ultrasound imaging and fluorine MRI. Oral presentation at the Biomedical Engineering Society annual meeting 2019, Philadelphia, PA.

Crowe, W.N., Wang, L., Zhang, Z., Varagic, J., Bourland, J. D., Chan, W. D., Habib, A. A., Zhao, D., MRI Evaluation of the effects of whole brain radiation on breast cancer brain metastasis. Oral presentation at the Biomedical Engineering Society annual meeting 2018, Atlanta, GA.

Skills

Computer: MATLAB • AutoCAD Inventor • Fusion 360 • MS Office • Skype • Canvas • Adobe Photoshop • Adobe Premiere • Adobe Illustrator • Cura • Arduino Engineering: Machining • Welding • Soldering • Circuit Design • Mechanical Design • Mathematical Modeling • 3D Printing • Mechatronics • Renewable Energy Systems • Image Analysis

Soft: Problem Solving • Scrum • Leadership • Teamwork • Communication • Planning • Creativity • Teaching • Conflict Resolution

References Available Upon Request

Contact this candidate