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Manager Lean Six

Location:
Bangalore, Karnataka, India
Salary:
130000
Posted:
December 16, 2020

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Resume:

Dr. KRISHNAN RANGANATHAN M.Sc., Ph.D., MBA

E-Mail: adip5k@r.postjobfree.com Tel: +91-809-***-****

https://www.linkedin.com/in/drkrishnanranganathan/ Executive Summary:

Highly adaptable Research Scientist - Business-focused, global mindset with extensive experience in both academic and industry. Internationally mobile MBA professional with highly collaborative skills. Proactive and driven to cultivate sustainable solutions for global challenges. Seeking a new career opportunity in industry, where I can apply my management and technical skills and experience. Educational Qualifications:

MBA. (General Management -2018-2019): University of Edinburgh Business School, Scotland, UK MBA International Exchange Program (Apr2019-Aug2019): MGSM, Sydney, Australia Ph.D. Polymer Chemistry (2000-2004): Central Leather Research Inst. & University of Madras, India Thesis Title: Kinetics, synthesis and characterization of Homo and Block Copolymers by ATRP M.Sc., Inorganic Chemistry (1996-1998): University of Madras, India B.Sc., Chemistry (1993-1996): University of Madras, India Project Management:

• PMP Certified Project Professional - Have led projects from pharmaceutical R&D lab and transfer process and product technology to manufacturing site with pilot plant trial batch execution

• Trained Lean Six Sigma Green Belt - For process improvements - Produce consistent high-quality products with least waste and minimal number of defects with low Cost-of-Quality (COQ)

• Led purification team in industrial setup for Angiomax® (Bivalirudin) - Peptide drug molecule - Product launched in US Market on 06-June-2017 https//lnkd.in/fFXNG5c: US$ 450M

• Good analytical knowledge to prioritize the work load and negotiation skills with different functions to complete the project work with timeline and approved budget Technical:

• 15+ years of experience in Research & Development (R&D) - Polymer/Organic Chemistry Field

• Transferable technical skill sets in Pharmaceutical & Specialty Chemical industry

• Compliance of - Good Laboratory Practices (GLP) at R&D lab - cGMP at the manufacturing site

• Analytical characterization data analyses - Polymer & Organic molecule structure prediction

• Implementing Standard Operating Procedures - Instruments-processes & Design of Experiments Leadership:

• Experience in setting up new R&D lab - Trained junior staffs & students in various research projects

• Led a R&D team (10+) for Product, Process development of Polymer & Peptide API’s in the R&D Lab - Transferred the process technology to the production site for commercialization Communications:

• Author for (18+) peer-reviewed high-impact publications - From work conceptualization, data analyses, writing & communications to journals (Total > 466 citations) Dr.Krishnan Ranganathan - Publications.pdf

https://www.slideshare.net/KrishnanRanganathan2/dr-krishnan-ranganathan-research-publica- tions-233503451

• Presented research work in many national and international conferences - Active participant in group discussion, knowledge exchange and further collaboration

• Member in several professional scientific organizations (American Chemical Society & Controlled Release Society-USA, CRSI & SPS - India) & Reviewer in international peer-reviewed journals Dr. KRISHNAN RANGANATHAN M.Sc., Ph.D., MBA

E-Mail: adip5k@r.postjobfree.com Tel: +91-809-***-**** Strategy:

• Specialized in New Venture Creation - From concept to implementation and commercial setup

• Negotiations - Bring consensus from multiple stakeholders to carried out the projects

• Carried out Strategy and Sustainability analyses of RBS, Virgin groups - Able to apply business concepts to run the businesses competitively with calculated risk in uncertain market conditions Work Experience:

Research Scientist - Institute of Chemical & Engineering Sciences, Singapore Oct2010-Sep2018

• Received SERC funding for - Bioderived UV Absorber Polymers Project - SG$ 240000 for 2.5 years

• In-charge of MALDI-TOF MS Instrument (Value: SGD $500K) - Developed molecular weight characterization, end-group analysis, and copolymer composition for polymers

• Engaged technical projects with specialty chemical industries (Croda, Singapore, BASF, Germany).

• Have developed various Polymerization Techniques to produce polymeric materials for different applications: Water-based coatings, Hard disk coating, Actives loaded polymeric capsules, etc

• Fine-tuning Structure & Property relationship of polymers for various applications

• Published research articles (10+) in leading peer-reviewed Chemical Science journals Research Fellow - National University of Singapore, Singapore Sep2009-Sep2010

• Identified and Developed biocompatible polysaccharide polymer scaffolds for skin tissue regeneration in Water medium for - Regenerative Medicine applications

• Published two research articles in peer-reviewed Medicine and Materials interdisciplinary journals

• Supervised Final Year Graduate students for their Project dissertation Deputy Manager - Dr. Reddy’s Laboratories Limited, India (Led 3 Projects) Jan2007 - Aug2009 Copaxone® (Glatiramer Acetate - Injectable: 20mg/mL) Market Value: US$ 4.5B

- Setting up a new R&D lab and Analytical instrumentation for polypeptide analysis - Installation & SOP

- Training Junior staff for process and product development - Maintenance on Lab safety

- Developed highly complex Polypeptide drug molecule from four Amino acids N-carboxyanhydrides

- Prepared new standards & analytical characterization according to US Pharmacopeia (USP) Angiomax® (Bivalirudin - Injectable: 250mg/vial) Market Value: US$ 450M

- 20 Amino acid containing linear peptide molecule from 10 different amino acids

- Process, cleavage of peptide from Wang-resin using TFA - Preparative HPLC purification & Freeze drying - Completed validation and successfully launched commercial production Elmiron® (Pentosan Polysulfate - Capsule: 100mg) Market Value: US$ 490M

- Derived from natural Polysaccharide xylan raw material

- Sulfonation followed by oxidative depolymerization - Purification by hollow fiber membranes Postdoctoral Fellow - University of British Columbia, Vancouver, Canada Sep2004 - Nov2006

• Hydrophobic drug delivery Applications: Developed thermoresponsive polymeric micelles from Hyperbranched Polyglycerol (HPG) core with responsive shell (T, pH) structures

• Surface Modification: Hydrophilic polymer brushes attached on polystyrene latex particles by ATRP/RAFT Technique - Further applied this concept to PVC blood storage bags to increase the Platelet Rich Plasma self-life (PRP - Current self-life - 5 days) Awards:

2004 - Canada Institute of Health Research (CIHR) & Centre for Blood Research - Postdoctoral Research Fellowship on Strategic Training Program and Transfusion Science (STPTS) 1999 - Council of Scientific and Industrial Research (CSIR), India - Doctoral Research Fellowship and Lectureship



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