Manager Manufacturing expert
Resume:
Dr. Refael
Aharon
Inventor, Entrepreneur,
Scientist
Personal Info
Address
California
Phone
adi623@r.postjobfree.com
www.linkedin.com/in/refaelaharon
Academic Qualifications
2006 - 2007
CRA (Clinical Research
Associate), Israel
2004 - 2006
Humphrey Center for
Experimental Medicine and
Cancer Research, Hebrew
University
Faculty of Medicine, Jerusalem
Post-doctoral - Discovery and modulation
of Osteoclasts Aquaporins
1999 - 2004
Feinberg Graduate School of
the Weizmann Institute of
Science, Rehovot, Israel
Department of Plant Genetics
PhD - Genetic manipulation of three
model plants Aquaporin modulation to
create drought and salt
resistance, design and build Automatic
plants real time analysis.
1996 - 1998
The Hebrew University of
Jerusalem, Faculty of
Agriculture, Rehovot, Israel
MSc- Horticulture Department. The work
was on water stresses (drought and salt)
in plants.
1993 - 1996
The Hebrew University of
Jerusalem, Faculty of
Agriculture, Rehovot, Israel
B.A.
An innovative, diligent, and detail-oriented pharmaceutical scientist with 18+ years of experience in identifying and managing new product opportunities. Adept in overseeing research activities and designing biopharmaceuticals for bringing impactful products to the market. Adroit in successfully planning, resourcing, managing, and executing supply chain operations for commercial purposes. Apt in identifying project-related concerns, assuring the practical application of technology, and driving high performing teams to exceed organizational goals.
Professional Experience
2019 -
2020
Chief Technology Officer
V-Hemp Farms (California)
Conducted research and case studies on robust technologies and determined their probability of implementation.
•
Designed, delegated, and implemented operational procedures to fulfill the organization's current and future technological needs.
•
Developed new IP for extraction methods for cannabis-induced topicals, the formulation for edibles, etc. using different organic ingredients, like medical mushrooms, medical herbs, and hemp.
•
Implemented high-quality methods for CO2 extraction machinery, neuron stimulates formulation, tissue culture propagation, and others.
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Conducted functional analysis to identify essential production-level KPIs and executed them for better results.
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2018 -
2019
Chief Science Officer
ELL Holdings Hemp (California)
Performed supply chain management procedures by managing and operating manufacturing equipment to streamline the development of products.
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Executed unparalleled supply chain results by incorporating high-end process improvement procedures.
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Designed and developed innovative technologies, from concept to completion and converting raw materials into product deliverables.
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Engineered the development of different products for different brands, such as Trim vs. Flower.
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Conveyed information to the laboratory teams regarding regulatory policies and complied with them accordingly.
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Constructed relevant SOPs for results-driven product development to ensure optimal results.
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Performed outcome-driven data analytics steps and prepared, insightful reports for future results.
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Generated adequate scientific documents to streamline the road to the successful delivery of products.
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2017 -
2020
Chief Science Officer
Medicine-Box (Nevada City)
Manage analytical activities and project procedures to meet strategic and project goals.
•
Formulate and develop several herbs and mushrooms product line, with products such as tinctures, tea, pills, roll-ons, and more.
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Assure that the testing equipment is adequately calibrated and maintained to ensure accuracy in the testing quality.
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Prepare relevant SOPs to facilitate the evaluation and feedback of production data to improve business outcomes.
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Supervise laboratory staff and ensure that they maintain high-quality standards for laboratory practices.
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Administer manufacturing in a licensed facility and ensure all facets of supply chain management are executed.
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2018 -
2019
Technology Specialist
Simple Garden (Los Angeles)
Developed Real-time Plants Analysis sensors to completely automate Plants Growth systems.
•
Guided implementation of the enterprise-level security strategies for the network, disaster recovery, and endpoint protection.
•
Prepared technological innovation includes revamping fertilizers, water pumps, and soil fertility for better outcomes.
•
Awards and Accolades
Inventor of over 25 patents registered in
different stages
BMW Worldwide – 2015
Clean Tech CEO of the Year, USA
Patents
Automatic Metabolic stimulator system
Extraction Methods
Applied Clean Tech patent portfolio
(extraction of cellulose from waste water)
Drug for Osteoporosis – plant extract that
targeting the Osteoclasts
Drug for fatty liver using desert plant
extract
Methods for extracting vital compounds
from medical plants.
Formulation of Edibles/topicals diet peal,
sleep, Cancer, anti-aging, Slow release
CBD
Showcased excellent plant physiology expertise and enhanced plants' growth and development.
•
2017 -
present
Drug Development, Bioinformatics, Immunology, Genetic Engineer and Lab Analysis Consultant
Freelance
Proficiently optimize several extraction and manufacturing procedures, along with improving the outcomes for all relevant equipment.
•
Devise results-driven processes to improve the production of several cannabis-based products and conduct feasibility for new pharmaceutical products.
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• Conduct optimization of procedures to enhance bioavailability and functionality. Execute plants and human cells genetic transformation, from gene isolation to functional transgenic plant, Western Blot, DNA fingerprint, GUS analysis, and others.
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Expertise in several analytical methods, including ICP-MS, LCMS-MS, HPLC, PH, RH, soli pathogens.
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Conduct in-process control protocols and administer manufacturing strategies under Current Good Manufacturing Practice regulations.
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Adept with general molecular biology skills, such as RNA isolation, DNA manipulation, electrophoresis, gel staining, and more.
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Research and perform different lab experiments to further optimize formulations and manufacturing processes.
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Perform a myriad of operations, such as supply chain management, product development, waste management, manufacturing machinery, and budgeting.
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Strategize and plan activities for sold orals, infused oils, capsules, liquid solution, sterile injectables, and prepare feasibility reports on potential pharmaceutical products.
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Record profiling of chemical compounds, including QA, planning/executing stability, and capitalizing on shelf-life studies.
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2008 -
2017
Founder CEO CTO
Applied Clean Tech Inc.
Spearheaded a team of chemical and mechanical scientists, along with pilot technicians, with the goal of maximizing business acumen.
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• Provided support to the clients by resolving their concerns efficiently. Managed relevant resources to conduct experiments and prepare insightful reports accordingly.
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2013 -
2017
Inventor CTO
Osteobuild Ltd (ProBone)
Developed functional food products in response to osteoporosis and bone cancer patients, resulting in shifting the pharmaceutical marketplace paradigm.
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Utilized natural products to target the mechanism of osteoporosis and bone cancer progression.
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2006 -
2010
Inventor and R&D Manager
Desert Labs Ltd.
Biotech Company that is developing new pharmacological formulations and products uses for appetite suppressant and fatty liver using vital extracts from local medical herbs. Tissue culture propagation protocol and tissue culture manufacturing operation, Preformed animal and human trial, word wide sales, GRASS, formulation, taste, extraction methods, machinery, tissue culture, IP. 2007 -
2008
Project Manager
Dead Sea - Tamar Regional Council
Developed academic projects for industrial companies in the field of minerals, drought, salt, environment, alternative energy and local medicinal plants. 2002 Founder Inventor R&D Manager
Green Ltd
Designed and implemented Tissue Culture Propagation Protocol to culture tissue in a nutrient medium.
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• Supervised a team of scientists to create edible shelf products.
• Authored clinical trials; to create procedures in treating fatty liver disease. Professional Attributes
Extraction process and machinery - CO2, ethanol, butane Regulation – compliance, SOP, licenses, bio-track (track and trace) Breeding, Tissue culture (propagation) protocols, plants genetic engineer Manufacturing processes – planning industry processes and monitoring Model and human trials – drugs, food supplements and functional food Waste management– compliance, machinery, processes, recycling technologies Environment – Alternative Energy, circular economy, Carbon Credit Formulation – reverse engineering, private label, high end products Medical herbs – composition, potency, products, formulations Publications
2013 Refael Aharon, Yosepha Shahak, Smadar Wininger, Rozalina Bendov, Yoram Kapulnik, and Gad Galili. Overexpression of a plasma membrane aquaporin in transgenic tobacco improves plant vigor under favorable growth conditions but not under drought or salt stress. Plant Cell 15: 439-447.
2006 Refael Aharon and Zvi Bar-shavit. Involvement of aquaporin 9 in osteoclast differentiation. Journal of Biological Chemistry 281: 193**-*****. 2005 Refael Aharon, Zvi Bar-Shavit. Aquaporin-9: Poster: a possible modulator of osteoclast differentiation. ASBMR 28th Annual Meeting Philadelphia, USA. 2004 Refael Aharon, Gad Galili, Abraham Blum and Yoram Kapulnik. Development of a high- accuracy electronic potometer for studying plant water use in real-time. http://www.plantstress.com/FilesPresentations/index.asp
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