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Resume:
CURRICULUM VITAE
Alemu Tekewe Mogus (Ph.D)
University of New Mexico, School of Medicine
Department of Molecular Genetics and Microbiology
Albuquerque, New Mexico, USA
Email: *******@*****.***
CURRENT POSITION
University of New Mexico
Postdoctoral Fellow
Albuquerque, NM, USA
May 2017-Present
EDUCATION
The University of Queensland
PhD, Bioengineering
National Institute of Pharmaceutical Education and Research M. Tech, Pharmaceutical Biotechnology
Addis Ababa University, School of Pharmacy
B. Pharm, Pharmacy
Brisbane, Australia
December 2016
Mohali, India
June 2007
Addis Ababa, Ethiopia
July 2004
RESEARCH EXPERIENCE
University of New Mexico Albuquerque, USA
Postdoctoral research; Supervisor: Professor Bryce Chackerian May 2017-Present Project: Broadly Neutralizing Antibody-Guided Virus-Like Particle Vaccine Design again HIV-1 Virus
The University of Queensland
PhD Research; Advisors: Professor Anton Middelberg and Associate Professor Linda Lua
Project: Bioengineering of Virus-Like Particle and Capsomere Vaccines against Rotavirus
Developed a high throughput screening method for enhancing the stability of modular vaccine candidates
Developed protein design strategies for addressing the effect of hydrophobic epitope on stability and in vitro assembly of modular virus-like particles
Brisbane, Australia
October 2012-April 2016
2
Developed multipronged approaches for designing and bioprocessing of modular virus-like particle displaying large antigenic modules
Addis Ababa University, School of Pharmacy
Co-investigator for the project “Phytochemical Screening of Antimicrobial Compounds from Ethiopian Medicinal Plants” in collaboration with Mr. Shemsu Umer (Addis Ababa University, School of Pharmacy) and Dr. Nigatu Kebede (Addis Ababa University, Aklilu Lemma Institute of Pathobiology) National Institute of Pharmaceutical Education and Research Master thesis project; Advisors: Professor UC Banerjee and Dr. Sawraj Singh
Project: Production, Purification and Characterization of Microbial Lipases for Enantioselective Resolution of Chiral Drug Intermediates and Drugs
Addis Ababa, Ethiopia
September 2009-June 2012
Mohali, India
August 2005-June 2007
TEACHING EXPERIENCE
Addis Ababa University, School of Pharmacy
Assistant professor, teaching Pharmaceutical Biotechnology and co-supervising masters students
Lecturer, teaching Pharmaceutical Microbiology, Immunology and, Immunological and Biological Products
Teaching assistant, Pharmaceutical microbiology
Addis Ababa, Ethiopia
December 2016-April
2017
September 2007-June 2012
September 2004-June 2005
LEADERSHIP
Addis Ababa University, School of Pharmacy
Assistant Dean (gave support for the Dean of the School of Pharmacy on academic affairs for undergraduate program) Addis Ababa, Ethiopia
April 2009-March 2011
PROFESSIONAL ASSOCIATIONS
Member for Ethiopian Pharmaceutical Association
Member for Ethiopian Society of Microbiology
July 2004-Present
December 2016-Present
SCHOLARSHIPS AND AWARDS
University of Queensland International (UQI) scholarship October 2012-March 2016 3
recipient
Ethiopian Ministry of Education Scholarship recipient Certificate and cup awarded outstanding undergraduate student of the year by the Ethiopian Pharmaceutical Association August 2005-June 2007
July 2004
Awarded gold medal from Addis Ababa University
Aklilu Lemma undergraduate scholarship recipient
July 2004
September 2002-June 2004
CONFERENCE PRESENTATIONS
1. Alemu Tekewe, Natalie K. Connors, Frank Sainsbury, Nani Wibowo, Linda H.L. Lua, Anton P.J. Middelberg. High-throughput screening for enhanced stability of modular vaccine candidates. 5
th
International NanoBio conference. 6-10 July 2014. Brisbane, Australia
2. Alemu Tekewe, Natalie K. Connors, Linda H.L. Lua, Anton P.J. Middelberg. Design strategies for production of modular rotavirus vaccine candidates. Australian Institute for Bioengineering and Nanotechnology students` conference. 2 October 2015. Brisbane, Australia
3. Alemu Tekewe. Virus-like particle and capsomere vaccines against rotavirus. Australian Institute for Bioengineering and Nanotechnology weekly seminar. March 2016. Brisbane, Australia
LIST OF PUBLICATIONS
1. Alemu Tekewe Mogus, Lihong Liu, Manxue Jia, Diane T. Ajayi, Kai Xu, Rui Kong, Jing Huang, Jian Yu, VRC Production Program, Peter D. Kwong, John R. Mascola, David D. Ho, Moriya Tsuji
*
, Bryce Chackerian
*
. Virus-like particle based-vaccines elicit
neutralizing antibodies against the HIV-1 fusion peptide. Submitted to NPJ: Vaccines, October 2020.
2. Alemu Tekewe, Yuanyuan Fan, Emilyn Tan, Anton P.J. Middelberg, Linda H.L. Lua. Integrated molecular and bioprocess engineering for bacterially produced immunogenic modular virus-like particle vaccine displaying 18 kDa rotavirus antigen. Biotechnology and Bioengineering 2017, 114: 397- 406. 3. Alemu Tekewe, Natalie N. Connors, Anton P.J. Middelberg, Linda H.L. Lua. Design strategies to address the effect of hydrophobic epitope on stability and in vitro assembly of modular virus-like particle. Protein Science 2016, 25: 1507-1516. 4. Alemu Tekewe, Natalie N. Connors, Frank Sainsbury, Nani Wibowo, Linda H.L. Lua, Anton P.J. Middelberg. A rapid and simple screening method to identify conditions for 4
enhanced stability of modular vaccine candidates. Biochemical Engineering Journal 2015, 100: 50-58.
5. Shemsu Umer, Gizachew Andualem, Fentabil Getnet, Haile Alemayehu, Alemu Tekewe, Nigatu Kebede. Antidiarrheal and antibacterial activities of hydroalcoholic extracts of Salvia schimperi benth from Ethiopia. International Journal of Pharmacognosy 2015, 2: 290-295.
6. Gizachew Andualem, Shemsu Umer, Fentabil Getnet, Alemu Tekewe, Haile Alemayehu, Nigatu Kebede. Antimicrobial and phytochemical screening of methanol extracts of three medicinal plants in Ethiopia. Advances in Biological Research 2014, 8: 101-106.
7. Shemsu Umer, Alemu Tekewe, Nigatu Kebede. Antidiarrhoeal and antimicrobial activity of Calpurnia aurea leaf extract. BMC Complementary and Alternative Medicine 2013, 13: 1-5.
8. Linga Banoth, Manpreet Singh, Alemu Tekewe, Uttam Chand Banerjee. Increased enantioselectivity of lipase in the transesterification of DL- -3-phenyllactic acid in ionic liquids. Biocatalysis and Biotransformation 2009, 27: 263-270. 9. Alemu Tekewe, Sawraj Singh, Manpreet Singh, Utpal Mohan, UC Banerjee. Development and validation of HPLC method for the resolution of drug intermediates: DL-3-Phenyllactic acid, DL-O-acetyl-3-phenyllactic acid and -mexiletine acetamide enantiomers. Talanta 2008, 75: 239-245.
REFERENCES
1. Professor Bryce Chackerian
Professor and Vice-Chair
Department of Molecular Genetics & Microbiology
University of New Mexico School of Medicine
***********@*****.***.***
2. Professor Anton Middelberg
UQ Pro-Vice-Chancellor (Research & International)
Australian Institute for Bioengineering and Nanotechnology (AIBN) Group Leader E-mail: *.**********@**.***.**
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3. Professor Linda Lua
Director for Protein Expression Facility
The University of Queensland
E-mail: *.***@**.***.**
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