Molecular Biologist/Geneticist

CONTACT

PHONE: +974-********

CITIZENSHIP: Singaporean

EMAIL:

***************@*****.***

ADDRESS:

PO Box 37893, Doha, Qatar

LINKEDIN:

LINKEDIN.COM/IN/RASHMI-

KULKARNI-951816145

https://orcid.org/000*-****-****-

6638

EDUCATION

Ph.D. (Molecular Genetics)

The Ohio State University, USA

2000-2005

M.Sc. (Microbiology)

University of Mumbai, India

1994-1996

B.Sc. (Microbiology)

University of Mumbai, India

1991-1994

EXPERTISE

Leadership & Training

Team Work

Project Management

Problem Solving

Grant & Manuscript Writing

MODEL ORGANISMS

E. coli

S. cerevisceae

C. elegans

D. rerio

X. tropicalis and X. laevis

Human cell lines

Mouse tumors

RASHMI PRADYUMNA KULKARNI

(formerly Rashmi Jayant Deshpande)

Molecular Biologist/Geneticist

PROFESSIONAL SUMMARY

Excellent scientific research and goal-oriented management skills with a in the research industry for 20+ years. Advanced expertise in Molecular Biology techniques, Mammalian Cell Culture, Cell Biology, Microscopy, Karyotyping, Protein Biochemistry as well as Hydroponics with a clear vision for the future WORK HISTORY

Managing Partner

Integrated Group, Doha, Qatar 2017-Present

Successfully built a shipping container for hydroponic farming of animal fodder

Mentored and trained farmhands in feeding methods of farm animals using freshly grown barley fodder

Quantified the effects of fresh barley fodder on the health and milk production in cows in collaboration with Al Maha Dairy Farms, Doha, Qatar Research Associate, Lab Manager, Post-Doctoral Associate Weill Cornell Medicine, Qatar 2010-2017

Elucidated the causative effects of Retnla on the metabolic syndrome using Calr+/+ mice

Decoded the role of Retnla on non-small cell lung cancers in Calr+/+ mice

Unravelled the mechanisms of miRNA-mediated regulation of STIM1 transcripts in breast cancer cells

Revealed mechanisms of inhibition of STIM1 function in mitosis using human cell lines and meiosis in Xenopus laevis oocytes using a quantitative proteomics approach Post-Doctoral Research Fellow

Institute of Molecular and Cell Biology, Singapore 2005-2009

Characterized the hypoxia-responsive and tissue-specific cis-elements controlling the expression of Erythropoietin (Epo) in Fugu rubripes

Cloned and characterized hypoxia-responsive and tissue-specific cis-elements controlling the expression of Epo in Callorhinchus milli

Identified and cloned the Xenopus tropicalis Epo locus and characterized its expression pattern

Graduate Student 2000-2005

Department of Molecular Genetics, The Ohio State University, USA

Elucidated multiple functions of POP-1 in P ectoblast specification in C. elegans

Dissected the mechanisms of POP-1 function in vulval specification in C. elegans Research Assistant 1999-2000

Centre for Genetic Health Care, Mumbai, India

Karyotyping, analysis and reporting of clinical peripheral blood, chorionic villus, placenta, amniotic fluid and fetal tissue patient samples Microbiologist & Analytical Chemist (R&D) 1997-1999 INTERESTS

Painting & Clay Modelling

Nutrition & Food Art

Gardening & Hydroponics

Writing Children’s Stories

LANGUAGES

English

Hindi

Marathi

SARA Chemicals and Research Center, Navi Mumbai, India

Developing novel methods to make pharmaceutical products using microbiological solutions

Developing assays for efficient detection and analysis of pharmaceutical products and intermediates

Q.C. Microbiologist & Analytical Chemist

Shirdi Chemicals, Navi Mumbai, India 1997

Setting up a fully functional microbiology laboratory

Chemical analysis of pharmaceutical intermediates TEACHING AND MENTORING

IMCB School Outreach Programme, Institute of Molecular and Cell Biology, Singapore 2005-2009

International Scholars School Outreach Programme, Institute of Molecular and Cell Biology, Singapore 2007

A-STAR-MOE Student Attachment Programme, Institute of Molecular and Cell Biology, Singapore 2006-2007

Graduate Teaching Assistant, Dept. of Molecular Genetics, The Ohio State University, USA 2001-2005

Graduate Teaching Assistant, Introductory Biology Program, The Ohio State University, USA 2000-2001

Lab Instructor, Department of Microbiology and Biotechnology, Ramnarain Ruia College, Mumbai, India 1996

PUBLICATIONS

Rashmi P. Kulkarni*, Asha Elmi*, Ethel Alcantara-Adap, Satanay Hubrack, Nancy Nader, Fang Yu, Maya Dib, Vimal Ramachandran, Hani Najafi Shoushtari, and Khaled Machaca [miRNA-dependent regulation of STIM1 expression in breast cancer Sci Rep. 2019; 9: 13076]

Fang Yu, Satanay Z. Hubrack, Sumita Chakraborty, Lu Sun, Ethel Alcantara- Adap, Rashmi Kulkarni, Anja M. Billing, Johannes Graumann, Colin W. Taylor, and Khaled Machaca [Remodeling of ER–plasma membrane contact sites but not STIM1 phosphorylation inhibits Ca2+ influx in mitosis PNAS May 21, 2019 116 (21-103**-*****]

Nahed El-Najjar, Rashmi P. Kulkarni*, Nancy Nader*, Rawad Hodeify and Khaled Machaca [Effects of Hyperglycemia on Vascular Smooth Muscle Ca2+ Signaling. Biomed Res Int. 2017;2017:3691349]

Nancy Nader, Raphael Courjaret, Maya Dib, Rashmi P. Kulkarni and Khaled Machaca

[Release from Xenopus oocyte prophase I meiotic arrest is independent of a decrease in cAMP levels or PKA activity. Development 2016 Jun 1;143(11):1926-36]

Nancy Nader, Maya Dib, Arwa Daalis, Rashmi P. Kulkarni and Khaled Machaca [Role for endocytosis of a constitutively active GPCR (GPR185) in releasing vertebrate oocyte meiotic arrest Dev. Biol. 2014 Nov 15; 395(2):355-66]

Nancy Nader, Rashmi P. Kulkarni, Maya Dib and Khaled Machaca [How to make a good egg! The need for remodeling of oocyte Ca2+ signaling to mediate the egg- to-embryo transition Cell Calcium Volume 53, Issue 1, January 2013, Pages 41–54 Review]

Rashmi P. Kulkarni, Sumanty Tohari, Adrian Ho, Sydney Brenner and B. Venkatesh

[Characterization of a hypoxia-response element in the Epo locus of the pufferfish, Takifugu rubripes Marine Genomics 2010 Vol 3 63–70]

Xin Li, Rashmi P. Kulkarni, Russell J. Hill, Helen M. Chamberlin [HOM-C genes, Wnt signaling and axial patterning in the C. elegans posterior ventral epidermis Dev Biol. 2009 August 1; 332 (1) 156-165]

Rashmi Deshpande, Takao Inoue, James R. Priess and Russell J. Hill [lin-17/Frizzled and lin-18 regulate POP-1/TCF-1 localization and cell type specification during C. elegans vulval development. Dev Biol. 2005 Feb 1; 278(1):118-29]

Takao Inoue, Helieh S. Oz, Debra Wiland, Shahla Gharib, Rashmi Deshpande, Russell J. Hill, Wendy S. Katz and Paul W. Sternberg [C. elegans LIN-18 Is a Ryk Ortholog and Functions in Parallel to LIN-17/Frizzled in Wnt Signaling. Cell 2004 Sep 17; 118(6):795- 806]

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