Chemical Engineering Assistant

ANIRUDDHA SHIRODKAR

**.***************@*****.*** 859-***-**** www.linkedin.com/in/aniruddha-shirodkar

SUMMARY

Scientist/ Engineer with extensive experience in laboratory experiment design and material characterization

Six Sigma and Lean Manufacturing: Cognizant in Design of Experiments (DOE), Statistical Process Control (SPC), Continuous Improvement (Kaizen), Process capability (Cp, Cpk), 5S, FMEA, Root Cause Analysis.

Possess working knowledge of High Pressure Liquid Chromatography(HPLC), Differential Scanning Calorimetry(DSC), X-ray Photoelectron Spectroscopy(XPS), Scanning Electron Microscopy(SEM), Dynamic Light Scattering(DLS), Fourier Transform Infrared Spectroscopy(FTIR) and UltraViolet(UV) spectroscopy.

Cognizant with basics of cGMP and OSHA regulations.

EDUCATION

University of Kentucky, Lexington, KY May’20 Master of Science, Chemical Engineering GPA: 3.5/4.0

Institute of Chemical Technology, Mumbai, India May’17 Bachelors of Chemical Engineering GPA: 7.73/10.0

Relevant Coursework: Advanced Chemical Reaction Design, Biostatistics, Chemical Engineering Operations, Chemical Project Economics, Process Control, Material Characterization Techniques, Engineering Drawing

RELEVANT EXPERIENCE

Graduate Research Assistant, University of Kentucky, Lexington Jan’18-May’20

Determined the selectivity of a system, consisting of carrier molecule impregnated lipid pore filled silica membranes, towards different saccharides using HPLC.

Carried out development of a colloidally stable system, involving the insertion of carrier molecules into lipid bilayers confined within the pores of nano-size silica particles.

Carried out the characterization studies of the structural changes in the system using Differential Scanning Calorimetry (DSC). Optimized the amount of lipid filled within silica nanopores to generate colloidally stable particles.

Utilised the insights gained from the data to determine the affinity of molecule towards lipid bilayers-suitable for applications involving oral administration of drug loaded pore confined lipid-based formulations.

Undergraduate project, Institute of Chemical Technology, Mumbai, India Aug’16-Apr’17

Worked on a techno-economic feasibility report to produce 1200 TPA of an Active Pharmaceutical Ingredient (API) Metronidazole.

Determined the market scenario of the product, conducted a literature survey of product synthesis steps and chose a suitable plant site.

Designed multi-step batch processes, charted out PFDs and P&ID diagrams and carried out risk assessment using HAZOP and HAZAN

Carried out intensive economic analysis of plant installation.

Intern, Snowtech Equipments Pvt. Ltd., Mumbai, India Jun’16-Jul’16

Performed design and analysis of experiments for the quantification of the heat and mass transfer properties of axial and radial impellers to design equipment for stirred tank reactors.

Lead a team of four interns and collaborated with the academia and the director of the establishment for the planning and execution of experiments. Documented relevant training materials for future research and development interns.

Translated the experimental results into preliminary processes involved in installation of pilot scale plants.

Intern, Bhabha Atomic Research Centre, Mumbai, India Jun’15-Jul’15

Synthesized carboxyl functionalized carbon nanotubes (CNT’s) to effect the chemisorption of neodymium onto the CNTs. Achieved a 45-50% uptake of neodymium uptake by CNT’s within 15 minutes of chemisorption-the quantification of which was done using Inductively Coupled Plasma Atomic Emission Spectroscopy (ICP-AES).

Determined the chemisorption kinetics of neodymium onto CNTs-which was found to follow pseudo-second order kinetic model. Analysed the possibility of intra-particle diffusion of neodymium, from the bulk solution to the interior of CNTs, to be the overall rate-determining step.

SKILLSETS

Software Skills: MATLAB (intermediate), Statistical Analysis-JMP (basic), Microsoft Office (Excel, Word, Powerpoint, Visio), SolidWorks

Extracurricular Activities:

Event coordinator of Indian Student Association, University of Kentucky.

Assumed the role of an event head at Vortex, a technical festival of Institute of Chemical Technology, India

Bagged a 2nd position among 20 delegates in Model United Nations (MUN) event held in India.

Coordinated with a team of five to fundraise INR 10,000 on the streets of Mumbai in an event named ‘Mahamandi’, organised by NITIE, India. The proceeds were used by an NGO involved in disseminating education to underprivileged children.

Description

The Scientist II - QC is responsible for performing testing of raw materials, in-process and finished pharmaceutical dosage forms, products on stability, cleaning verification samples following written procedures and applicable SOPs, calculating and reporting results on applicable specification documents, participating in method transfer activities within departments or between facilities or organizations. Provides feedback on systems and analytical procedures to promote continuous improvement and enhancement of compliance posture.

Essential Functions

Performs chemical analysis of raw materials, in-process and finished pharmaceutical products, including products on stability, according to written methods or compendial methods as applicable, material specifications, using analytical techniques such as IR spectroscopy, UV-Vis spectroscopy, and chromatographic techniques, adhering to company policies as identified in standard operating procedures (SOPs).

Prepares samples for analysis involving thorough cleanliness and complex steps for analysis using chromatographic techniques and analyzes. Creates and maintains laboratory record documentation (notebooks and computer-based), documents exact steps followed during analysis execution, calculates and reports results in a timely manner.

Actively participates in method transfer activities between facilities within the organization or between organizations.

Actively participates in and leads investigation of out-of-specification laboratory results, when required.

Performs physical analysis involving complex techniques such as X-ray diffraction, DSC, Malvern mastersizer.

Prepares and executes method transfer protocols, method verification/validation protocols as and when required.

Additional Responsibilities

Assists, as and when needed, senior scientists working in the laboratory.

Ensures that expired chemicals and reference standards are removed from laboratory area, performs calibration of dissolution apparatus, FT-IR, UV-Vis spectrophotometer, HPLC, GC as assigned by the supervisor.

Standardizes API for use as in-house reference standard as assigned.

Interacts with newly hired laboratory technicians or Assistant Scientists for providing hands-on training on simple analytical techniques and laboratory instruments.

Education:

Bachelors Degree (BA/BS) Chemistry or related science discipline - Required

Master Degree (MBA) Chemistry or related science discipline - Preferred

Experience:

3 years or more in Bachelors Degree (BA/BS) -Testing of chemicals/pharmaceutical products, 3 years or more

1 year or more in Master Degree (MA/MS) -Testing of chemicals/pharmaceutical products, 1 years or more

Skills:

Must be precise and consistent in day-to-day analysis, using sophisticated analytical instruments. - Advanced

Must be familiar with out of specification and out of alert limit investigations. - Intermediate

Must be able to execute compendial procedures involving complexity. - Intermediate

Must be familiar with cGMP and OSHA regulations. - Intermediate

Must be able to effectively communicate results, problems or issues, verbally as well as in writing. - Intermediate

Must be computer literate and savvy with MS office applications, software programs related to LIMS. - Intermediate

Must be able to work in a team environment and be flexible to easily adapt to changes in assignments. - Intermediate

Must follow safe practices as identified in appropriate MSDS during working with chemicals, and must follow applicable state and federal regulations. - Intermediate

Must be capable of maintaining clear and concise laboratory records and communicating clearly both within and between departments. - Intermediate

Must be thoroughly familiar with cGMP applicable to laboratories in pharmaceutical settings and with method verification/validation concepts. Must be able to review laboratory records to ascertain compliance with applicable specifications, methods, and SOPs. - Intermediate

Must be able to assume a role of a leader in team environment as and when required. - Beginner

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