Medical Clinical Research

Dr. Shobhana Nayak-Rao MD (Int. Medicine),DNB (Nephrology),MRCP(SCE), FASN

Email: **************@**********.***

Trained Nephrologist with about 15 years experience in the field of nephrology. Additional fellowship in clinical nephrology from the University of Ottawa. Has vast clinical and academic experience working in three countries including the Middle East and Canada. Strong academic credentials throughout with focus on clinical research as evidenced by several publications in leading journals and involvement and initiation of research projects.

Medical License : Permanent valid license from Karnataka Medical Council(KMC) Reg no 44.000, INDIA

PROFESSIONAL EXPERIENCE:

Part time Clinical Fellow Victoria Hospital, London Health Sciences Centre and Research team, ICES, London, Canada- Sep 2019 to current

Having moved to Canada for personal reasons, I am at present a part time clinical fellow based in Victoria Hospital in London, Ontario, Canada. I work closely with Dr Amit Garg who has been a pioneer in various national and international projects in the field of clinical nephrology and living donor transplantation. My aim would be to gain the necessary experience and expertise in conduct of large scale clinical research projects in nephrology concentrating on the field of acute kidney injury, chronic kidney disease (Uncertain etiology ) and women’ health in nephrology.

Previous Work Experience:

Associate Prof in Nephrology, Head of Department, Nephrology, K.S. Hegde Academy, Mangalore – Jan 2016 to Sep 2019

Associate Professor and Head at the Dept of Nephrology at K.S Hegde Medical Academy with focus on undergraduate and postgraduate teaching. The institution has a 1000 bedded hospital and I was the in charge of the smooth functioning of the unit. My focus and aim during my tenure was to enhance and develop the departmental clinical research activities and make it a regional access center for nephrology clinical research activity. In this regard a restricted grant research grant towards diabetic nephropathy research was issued to the department and the NITTE University and this project is still ongoing at the moment.

Jun 2015- June 2016 : Completed the Global Clinical Scholar Training programme(GCSRT) of the Harvard Medical School a comprehensive research methodology and biostatistics program. Being part of this program has given me the opportunity to liaison and work with various professionals from around the globe and also given me operational knowledge of STATA with the initial fundamentals of biostatistics .

Consultant Nephrologist, Sri Krishna Sevashrama Hospital, Bangalore,India Nov 2013 –May 2014.

Consultant nephrologist at a private charitable and voluntary funded hospital with a 20 bedded hemodialysis centre with 80-85 CKD patients on maintenance hemodialysis.

Staff Nephrologist, St Martha’s Hospital,Bangalore,India July 2012 to July 2013

Consultant nephrologist and in charge of the nephrology services at St Martha’s hospital which is a 500 bedded Christian Missionary Hospital,one of the oldest hospitals in the city of Bangalore. The hospital is accredited to the National Board of Examinations for internal medical postgraduate degree and work also involved postgraduate teaching in the area of nephrology.

Fellowship in Clinical Nephrology and Transplantation, University of Ottawa March2011-March 2012

Completed a one year fellowship programme in clinical nephrology and transplantation from the University of Ottawa,one of the leading academic and research institutes in Canada.

Good professional relations with the unit and positive feedback from all consultants in the department.

Bahrain Specialist Hospital, Bahrain Sept2007 –Dec 07

Nov 2008 - Jan 2010

SPECIALIST – NEPHROLOGY AND INTERNAL MEDICINE

Focus of care and management of patients with acute and chronic renal disease in addition to management of internal medicine patients with a special emphasis on preventive nephrology

Bahrain Specialist Hospital is a tertiary care institution with good infrastructure and trained support staff. The hospital also has an active academic programme to which I had been a regular contributor.

St John’s Medical College Hospital, Bangalore July 2005 – April 2007

LECTURER – DEPARTMENT OF NEPHROLOGY

Subsequent to the completion of my nephrology subspeciality training,I was part of a team of 4 nephrologists in the department, reporting to the head of the department. Actively involved with ongoing research projects in the department as well as in undergraduate and postgraduate training programmes with publications in reputed journals.

EDUCATION & AWARDS

MRCP(UK) specialist certification program in Nephrology in March 2015.

Fellow of the American Society of Nephrology-fellowship in June 2008 for academic excellence and contribution to research in the field of Nephrology.

National Board Certification in Nephrology (DNB) at Kamineni Hospital, Hyderabad under the guidance of eminent Indian nephrologist (late) Dr J.C.M.Shastry- June 2005

Post graduation in Internal Medicine (M.D-General Medicine) from Kasturba Medical College Mangalore- July 2000.

Undergraduate Medical education (MBBS) from Sri Devaraj Urs Medical College, Kolar, Bangalore University –June 1995 with the mandatory one year internship at the St Johns Medical College Hospital,Bangalore

Distinctions:

Best outgoing student from undergraduate medical college in 1995 with recipient of 20 gold medals

First rank holder at the undergraduate level from Bangalore University –1996

RESEARCH INTERESTS and ONGOING PROJECTS:

EPO use in patients with CKD and Cancer

Heavy metal exposure and risk of CKD progression

Heat shock protein and its role in recovery from AKI

Alternative medication use in patients with CKD

PAPER PRESENTATIONS & PUBLICATIONS

Publications till date: With a total impact factor of more than 35

Top six publications:

1.‘Acute Renal failure during pregnancy-an unusual cause’-Nephrology Dialysis Transplant 2007; Vol 22,264-5. Impact factor 4.08

2.‘Genitourinary tuberculosis after renal transplantation-A report of 3 cases with a good clinical outcome’-American Journal of Transplantation 2007;7:1862-64.Impact factor 5.68

3.Traditional Medicines and Kidney Disease in Low and Middle –Income Countries: Opportunities and Challenges Seminars Nephrol 2017; 37(3) : 245-59. Impact factor 3.77

4.‘Achieving effective analgesia in patients with chronic kidney disease-a review of analgesics in renal failure'-Journal of Nephrology 2011; 24(1): 35-40.Impact factor 1.35

5.Erythropoeitin use in CKD patients with cancer-to tread with caution’- Journal of Nephrology 2013;26: 829-35.Impact factor 1.35

6.The role of heat shock proteins in kidney disease’- Journal of translational and Internal Medicine 2016; 4: 114-7.Impact factor 1.48

7.Complementary and alternative medication (CAM) use in patients with end-stage renal disease on hemodialysis : A cross sectional study from Southern India. Indian Journal of Applied Research 2018;8(3): 251-53. Impact factor 5.39

Other publications:

8.‘Medullary Sponge Kidney In Association With Mullerian Agenesis ’ Clinical Nephrology 2003 ; 59:123-5

9.'Anemia after renal transplantation : a persisting problem'-Indian Journal of Nephrology 2005;15:239-242.

10.‘Non lymphomatous hematogical malignancies after renal transplantation’- Indian Journal of Nephrology 2006;16:174-76.

11.‘Coping strategies of patients on CAPD’-Indian Journal of Peritoneal Dialysis 2006;Vol 11: 9-12.

12.‘Peritoneal Mucormycosis in a patient on continuous ambulatory peritoneal dialysis’- International Journal of Peritoneal Dialysis 2007; 2:216-7.

13. ‘Uveitis following anti-snakevenom therapy’-The Journal of Venomous Animals and Toxins 2007;13:130-34.

14.‘An unusual Toxic cause of hemolytic Uremic Syndrome’-The Journal of Toxicology 2007;32(2): 197-99.

15.‘Crescentic transformation in primary membranous nephropathy-association with anti-GBM antibody’-Saudi Journal of Kidney diseases and Transplantation 2007; 18(4);599-602.

16.‘Nephrotic syndrome following multiple bee stings’-Indian Practitioner 2007;60(11):723-5.

17.‘Extensive cerebral venous thrombosis in a renal allograft recipient’-Saudi Journal of Kidney Diseases and Transplantation 2008;19(1):90-93.

18.‘Demographics and social factors associated with acceptance of treatment in patients with chronic kidney disease’-Saudi Journal of Kidney diseases and Transplantation 2008;19(1):132-6.

19.‘Cancer screening in End –stage renal disease-A brief Review’ – Saudi Journal of Kidney Diseases and Transplantation 2009; 20(5): 737-740.

20.'Review of aminoglycoside use in renal failure'-Indian Journal of Nephrology 2010; 20: 121-4.

21.'Pregnancy after kidney donation-placing things in perspective'-Saudi Journal of Kidney Diseases and Transplantation 2011; 22(3): 552-3.

22.‘Unusual presentation of renal vein thrombosis with pulmonary artery embolism’ –Saudi Journal of Kidney Diseases and Transplantation 2013;24(3): 566-570.

23.Severe hypercalcemia unmasked by Vitamin D in a patient with sarcoidosis’-Indian Journal of Nephrology 2013; 23: 375-7.

24.‘Nephrogenic ascites-still an intractable problem?’-Saudi Journal of Kidney Diseases and Transplantation 2015; 26(4); 773-777.

25. ‘A patient with hemodialysis intolerance and eosinophilia’- Saudi Journal of Kidney Diseases and Transplantation 2015; 26(2): 366-67.

26..’Percutaneous native kidney biopsy in patients receiving antiplatelet agents-is it necessary to stop them routinely?’-Indian Journal of Nephrology 2015; 25(3): 129-32.

27.‘‘Obstructive nephropathy in a post-transplant pregnancy’-Saudi Journal of Kidney Diseases and Transplantation 2016:27; 1290-2.

28.‘Hyponatremia secondary to acute urinary retention-‘Saudi Journal of Kidney Disease and Transplantation 2017; 28(2): 392-95.

29.‘Stroke in patients with Chronic Kidney Disease-How do we approach and manage them? –Indian Journal of Nephrology 2017; 27(3): 167-71.

30.‘Fatal Type –B lactic acidosis with HIV associated lymphoma- a case report with review of literature’. Journal of Renal Medicine 2017; 1(2): 8.

31.‘Revisiting acute kidney injury in adult minimal change disease-a case report and review of literature’. ARC Journal of Nephrology 2017, Vol 2 : 1-5.

32.‘Plasmapheresis: a retrospective audit of procedures from a tertiary care centre in Southern India’- Indian Journal of Critical Care Medicine 2017;21(12): 875-60.

33.‘Applicability of the Cleveland Clinic Scoring Tool(CCST) in risk prediction of acute kidney injury after cardiac surgery in a South-Asian population’ –https://doi.org/10.1016/j.ihj.2017.11.022 in the Indian Heart Journal.

34.Emphysematous pyelonephritis – a case series from a single centre in Southern India –Journal of Clinical Nephrology 2018;02:20-24.

35.Marijuana Use and its effects on the Kidney –Asian Journal of Nephrology 2018; 1(1):1-6.

36.Proton pump inhibitor use and its relation to serum magnesium levels among hemodialysis patients: A single centre study in a South Indian tertiary care hospital. IP International Journal of Comprehensive and Advanced Pharmacology 2018; 3(2): 61-65.

37.Proton pump inhibitor and its relation to serum magnesium levels among hemodialysis patients: A single centre study in a South Indian tertiary care centre. Int J Comprehensive Adv Pharmacology 2018; 3(2): 61-65.

38.Efficacy of tacrolimus in steroid dependent and steroid resistant childhood nephrotic syndrome-A retrospective study. Int J Comprehensive Adv Pharmacology 2018; 3(3): 104-108.

39.‘An unusual cause of nephrotic syndrome presenting in pregnancy’ accepted for publication in Journal of Clinical Gynecology and Obstetrics.

40.‘Complementary and alternative medication use in chronic kidney disease patients : a single centre study from tertiary care centre in Southern India –accepted for publication in Saudi Journal of Kidney Diseases and Transplantation.

41. Pregnancy related Acute Kidney Injury : is it a declining entity ? Systematic review of data over a twenty year period from Asia –accepted for publication in the The Open Urology and Nephrology Journal.

42.Acute toxin associated kidney injury with renal recovery –International Journal of Current Research 2019; Vol 11(3).

43.Spontaneous non traumatic subarachnoid hemorrhage in a hemodialysis patient –International Journal of Current Research 2019; Vol 11(6) : 4992-4.

44. Endovascular intervention for central venous stenosis in hemodialysis patients: a single centre experience-accepted for publication in Indian Journal of Nephrology

45. Addressing the Gender disparity in access and delivery of chronic kidney disease care-the next focus of care-accepted for publication in Indian Journal of Applied Research .

Recent Achievements :

1)Received a research grant from the RSSDI( Research Society for Diabetes in India) towards project titled’ Newer biomarkers in the prediction of Chronic Kidney Disease patients with diabetic nephropathy’- this study has to be initiated with the department of Biochemistry.

2) Principal co-ordinator for study of CKD-U and modification of disease with oral probiotics… this project is done in association with the Govt of Telangana and Kibow Biotechnologies.

Member of the Young Nephrology Mentorship programme of the ISN since June 2016 and also a member of ISN –ACT with focus on improving nephrology research across the globe

External Reviewer for the following journals

1)Saudi Journal of Kidney Diseases and Transplantation

2)International Journal of Infectious Diseases

3) Therapeutic Apheresis and Dialysis

4) Renal Failure

5) Kidney and Blood Pressure Research

6) Journal of Clinical Nephrology

7) BMJ Case Reports

8) Research Gate

9) Journal of Urology and Nephrology

10) Clinical Nephrology

11) Annals of case reports

12) Current Hypertension Reviews

Scientific Memberships:

Life Member of the Indian Society of Nephrology (2005-current )

Member of the American Society of Nephrology (2007-2017)

International Society of Nephrology(2016 –current)

Professional references will be provided on request

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