Curriculum Vitae

Azadeh Abdi

*. Personal Information:

Address: 7th floor, No, 32, Hafez building, Sarve 23 Street, Pirouzi 63 Avenue, Mashhad, Iran Telephone Number: 009***********

Mobile: 009***********

E-mail: addyob@r.postjobfree.com

Date of Birth: 27/04/1979

Place of Birth: Mashhad

Nationality: Iranian

Marital status: married

2. Professional Experience:

5/8/2013 – Present Qualified Person

Company Saman daroo 8 pharmaceutical company

Main Responsibilities:

Responsible for the quality of the products and finally releasing them.

Responsible for the regulatory affaires.

In charge of Getting the marketing authorization or production licence for every new product.

Supervising the function of QA department.

Involving in clinical trials as the scientific representative of the company.

Giving the scientific consultations to the marketing team.

Supervising all the suppliers and the quality of the raw materials and starting materials for production.

In the company, Responsible to contact with the Iran FDA. 1/12/2010 – 1/8/2013 University Instructor in Phamacology Company Hamedan University of Medical Science

Topics which I have taught in the Hamadan University of Medical Science:

Drugs that act in the CNS (central nervous system)

Anti-depressants

Sedative-hypnotics

Opioid analgesics

Antipsychotics

Parkinson

’

s disease

Muscle relaxants

Local anesthetics

General anesthetics

Antisiezures

Drugs used in treatment of Gastrointestinal system

Chemotherapeutic drugs

Autonomic drugs

Drugs used in coagulation disorder

Drugs used in anemia, hematopoietic growth factors

Endocrine drugs

Gonadal hormones and inhibitors

Thyroid and antithyroid drugs

Adrenocorticostroids

Pancreatic hormones and antidiabetic drugs

Agents that affect bone mineral homeostasis

Drugs used in asthma

16/09/2008 – 5/11/2008 Pharmacist and Researcher in R&D Department Company Darsavin pars Co.

23/09/2003 - 22/11/2007 Pharmacist supervisor

Company private pharmacies

3. Researches

25/05/2006-28/07/2006 Researcher

Company Neuroscience Research Center, Shahid Beheshti University of Medical Sciences Project: "morphine exposure during pregnancy and breast feeding can affect anti- inflammatory, analgesia, tolerance and dependency responses to morphine in rat neonates".

12/01/2006 - 29/09/2009 PhD Thesis at Shahid Beheshti University Thesis” Apoptosis Inhibition Can Be Threatening in Aβ-induced Neuroinflammation, through Promoting Cell Proliferation”

15/11/2008 – 29/10/2009 A Member of Scientific Committee (quality assurance) Company Genian Daru Co.

7/11/2009 - 15/7/2010 Researcher

Company karolinska institute

4. Educational Background

2003 - 2009 Doctor of Philosophy in pharmacology

Shahid Beheshti University of Medical Sciences, Pharmacology Department, Tehran, Iran

1997 - 2002 Doctorate Degree in Pharmacy

Mashhad University of Medical Sciences, Pharmacy Faculty, Mashhad, Iran 5. Publications

Apoptosis Inhibition Can Be Threatening in Aβ-induced Neuroinflammation, Through Promoting Cell Proliferation. A. Abdi, H. Sadraie L. Dargahi, L. Khalaj, A. Ahmadiani

. Neuro chem Res (2011) 36:39–48

A quantitative assay for monitoring of autophagosome formation in cells depending on the phase of the cell cycle. Kaminskyy V, Abdi A, Zhivotovsky B. Institute of Environmental Medicine, Division of Toxicology, Karolinska Institute, Box 210, SE-171 77 Stockholm, Sweden. Autophagy 2011, 7:1, 83-90 Alginate protects NT2 neurons against H2O2-induced neurotoxicity. Bahareh Eftekharzadeha, Fariba Khodagholi, Azadeh Abdia and Nader Maghsoudi, Carbohydrate polymeras, 2010,79(4):1063-1072. Protective effects of lycopen and tomato extract against Doxorubicin-induced cardiotoxicity. Gholamreza Karimia, Mohammad Ramezanib, Azadeh Abdia Phytotrapy Reaserch,2005,19:912-914

Spinal Ischemic-Reperfusion Injury Protection by Acute Estradiol Administration in Male Rabbits. Leila Khalaj, Habibollah Peirovi, Fariba Khaodagholi, Azadeh Abdi, Leila Dargahi, fatemeh mohagheghi and abolhassan Ahmadiani. The Journal of physiology and pharmacology,Iranian society of physiology and pharmacology,2010, 14(1):1-11.

Cyclooxygenase (COX)-1 Activity Precedes the COX-2 Induction in Aβ- Induced Neuroinflammation. Leila Dargahi, Shiva Nasiraei-Moghadam

,Azadeh Abdi, Leila Khalaj, Fatemeh Moradi,Abolhassan Ahmadiani, J Mol Neurosci. 2011 Sep;45(1):10-21

Dietary supplementation with tBHQ, an Nrf2 stabilizer molecule,confers neuroprotection against apoptosis in amyloid β-injected rat. F.Nouhi, SK.Tusi, A.Abdi, F. Khodagholi, Neurochem Res, 2011 May;36(5):870-8. Acute 17β-Estradiol pretreatment protects against abdominal aortic occlusion induced spinal cord Ischemic-Reperfusion injury. Leila Khalaj, Habibollah Peirovi, Fariba Khodagholi, Azadeh Abdi, Leila Dargahi,Abolhassan Ahmadiani, Neurochem Res. 2011 Feb;36(2):268-80. Caspase inhibition in neuroinflammation induced by soluble β amyloid monomer, protects cells from abnormal survival and proliferation, via attenuation of NFқB activity. Azadeh Abdi, Fatemeh Mohagheghi, Homayoon Sadraei, Leila Dargahi, Leila Khalaj and Abolhassan Ahmadiani,Iranian society of physiology and pharmacology, 2010, 14(3): 211-219. 6. Presentations:

Cancer therapy and apoptosis

Apoptosis and signaling pathways

Alzheimer disease, pathology and recommended treatment

Nicotinic acetylcholine receptors and the regulation of neuronal signaling

Absorbtion and distribution

7. Congresses:

1- Mashhad Pharmaceutical congress, Iran, 2000.

2- Kerman pharmaceutical congress, Kerman, Iran, 2001. 3- First international symposium on molecular technology and apoptosis 30 th

July- 1th August

2005.

4- Second international symposium on molecular technology and apoptosis 26 th

-27

th

June

2007.

5- Iranian congress of Pharmacology and physiology, Mashhad, Iran, 2007. 6- 19

th

Iranian congress of physiology and pharmacology, Tehran, Iran, 2009 7- Nobel symposium NO: 144, the cell cycle and apoptosis in disease, 23-26 may 2010, Karolinska institute, Stockholm, Sweden.

8- 20

th

Iranian Congress of Pharmacology and Physiology, Hamedan, Iran, 2011. 8. Languages

Persian: native language

English: Excellent (writing/ reading/ speaking/ listening) 9. Techniques

Western blotting

Electrophoresis(SDS-PAGE)

TUNEL

PCR

Immunocytochemistry (ICC)

Immuno peresipitation (IP)

Flowcytometry

Cerebroventricular cannulation

Spinal cord cannulation

Rat perfusion with fixator

Stereotaxis surgery

Protein extraction

Cellular fractionation

Protein assay: brad ford and BCA

Tail flic test

Peltismometery test

Rat handling

Cell culture

Confocal microscopy

Gene transfection

Knocking down gene

10. Referees

a. Pro.Abolhassan Ahmadiani, Neuroscience Research Center and Pharmacology department, Shaheed Beheshti University of Medical Sciences and Health Services, Evin, Tehran, Iran. Mobile: +989*********

b. Dr.Alireza Azimi, Postdoctoral Fellow at Uppsala University, Department of Immunology, Genetics and Pathology, Stockholm,Sweden. Mobile: +46-76-262-**** linkedin.com/in/alirezaazimi

c. Pro.Nader maghsudi, Neuroscience Research Center, Shaheed Beheshti University of Medical Sciences and Health Services, Evin, Tehran, Iran. Mobile: +989********* d. Prof. Boris Zhivotovsky, The Institute of Environmental Medicine, Karolinska Institutet,Stockholm, Sweden.

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