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Xiuqing Gao

Ph.D. Candidate, Pharmaceutical Sciences

Texas Southern University

**** ******** ******, **, *****

832-***-****

adcg4l@r.postjobfree.com

PROFESSIONAL SUMMARY

Pharmaceutical scientist with 5+ years’ experience in drug development for pre-clinical pharmaceutical APIs. (1) Pharmacokinetic modeling using Phoenix WinNonlin and NLME software, (2) LC-MS/MS and HPLC-UV method development and validation for small molecules, (3) Supralingual, oral, intravenous development and characterization in Sprague-Dawley rats.

EDUCATION

2015 — Present Ph.D. Candidate – Pharmaceutical Sciences, Texas Southern University-Houston, TX, US 2009 — 2013 Bachelor of Science in Pharmacy, Yanbian University-Yanji, Jilin, China SKILLS

Formulation

Gold nanorods

Nanoparticles

Co-solvent

Instrument

LC-MS/MS

HPLC-UV

UV-Vis

Microfluidizer

Zetasizer

Software

Phoenix NLME

Phoenix WinNonlin

Empower

Analyst

Microsoft Office

SigmaPlot

In vivo

Blood, urine, tissue collection in rats

Supralingual, parenteral and oral dosing

in rats

RESEARCH EXPERIENCE

Texas Southern University, 2015 — Present Graduate Research Assistant

• Pharmacokinetic study of mycophenolate sodium by supralingual administration: development of pharmacokinetic model using Phoenix Non-Linear Mixed Effects (NLME) in rats.

• Development and validate LC-MS/MS and HPLC-UV method for oxaliplatin and mycophenolic acid in rat plasma and tongue tissue.

• CLBQ14 pre-clinical pharmacokinetic, tissue distribution and physicochemical property studies.

• Development and validation of a selective and rapid LC-MS/MS method for quantification of AC1LPSZG in rat plasma and urine.

• Synthesized the GNRs and conjugated the GNRs with anti-CAIX: applied laser treatment in vitro and in vivo

• Assist and conduct in the dosage formulations lab for Pharm D. students with preparation of emulsions, ointments, capsule and suppositories.

• Assist in the pharmacy calculations lab for Pharm D. students in chemical equivalency, electrolytes solution and milliosmoles calculation.

Yanbian University, 2012 — 2013 Internship

• Investigated bacitracin flexible nano-liposomes in a graduate project. Made bacitracin flexible nano-liposomes and optimized the prescription.

AWARDS & ACHIEVEMENTS

Oct. 2019 Graduate Student Travel Grant, COPHS, Texas Southern University Apr. 2019 Dean’s Award, COPHS, Texas Southern University Nov. 2018 Graduate Student Travel Grant, COPHS, Texas Southern University PUBLICATIONS

1. Xiuqing Gao, Lei Wu, Robert Y.L. Tsai, Jing Ma, Parnit K. Bhupal, Xiaohua Liu, Dong Liang, and Huan Xie,

“Pharmacokinetic study of mycophenolic acid by supralingual administration in rats.” (In Progress) Page 2 of 2

2. Xiuqing Gao, Robert Y.L. Tsai, Jing Ma, Parnit K. Bhupal, Xiaohua Liu, Dong Liang, and Huan Xie, “Determination and validation of oxaliplatin by a novel UPLC-MS/MS method: application to pharmacokinetics and tongue tissue distribution studies in rats.” (In Progress)

3. Xiuqing Gao, Jing Ma, Oscar Ekpenyong, Olaleye Omonike, Dong Liang, and Huan Xie, “Pharmacokinetic and evaluation of organic solvent-free CLBQ14 loaded solid lipid nanoparticles.” (In Progress) 4. Yuan Chen, Xiuqing Gao, Ritu Gupta, Jing Ma, and Huan Xie, “Development and validation of a selective and rapid LC-MS/MS method for quantification of AC1LPSZG in rat plasma and urine.” (In Progress) 5. Xiuqing Gao, Robert Y.L. Tsai, Jing Ma, Parnit K. Bhupal, Xiaohua Liu, Dong Liang, and Huan Xie, “Determination and validation of mycophenolic acid by a novel UPLC-MS/MS method: application to pharmacokinetics and tongue tissue distribution studies in rats,” in Journal of Chromatography B, Jan 2020. 6. Oscar Ekpenyong, Linh Nguyen, Xiuqing Gao, Jing Ma, Candace Cooper, Omonike Olaleye, Dong Liang and Huan Xie, “Pre-clinical pharmacokinetics, tissue distribution and physicochemical studies of CLBQ14, a novel methionine aminopeptidase inhibitor for the treatment of infectious diseases,” in Drug Design, Development and Therapy, Mar 2020.

7. Yuan Chen, Xiaomei Bian, Maureen Aliru, Amit A. Deorukhkar, Oscar Ekpenyong, Su Liang, Jyothy John, Jing Ma, Xiuqing Gao, Jon Schwartz, Pankaj Singh, Yuanqing Ye, Sunil Krishnan, and Huan Xie, “Hypoxia-targeted gold nanorods for cancer photothermal therapy,” in Oncotarget, May 2018. ABSTRACTS

1. Xiuqing Gao, Jing Ma, Robert Y.L. Tsai, Parnit K. Bhupal, Xiaohua Liu, Dong Liang and Huan Xie “Development and validation of a new UPLC-MS/MS method for measuring transmucosal delivery of oxaliplatin in vivo,” in American Association of Pharmaceutical Sciences, AAPS, (San antonio), Henry B. Gonzalez Convention Center, Nov 6, 2019.

2. Xiuqing Gao, Jing Ma, Robert Y.L. Tsai, Parnit K. Bhupal, Xiaohua Liu, Dong Liang and Huan Xie “Development and validation of a new UPLC-MS/MS method for measuring transmucosal delivery of mycophenolic acid in vivo,” in American Association of Pharmaceutical Sciences, AAPS, (San antonio), Henry B. Gonzalez Convention Center, Nov 5, 2019.

3. Yuan Chen, Xiuqing Gao, Ritu Gupta, Jing Ma, and Huan Xie, “Development and validation of a selective and rapid LC-MS/MS method for quantification of AC1LPSZG in rat plasma and urine,” in American Association of Pharmaceutical Sciences, AAPS, (San antonio), Henry B. Gonzalez Convention Center, Nov 5, 2019. 4. Xiuqing Gao, Jing Ma, Oscar Ekpenyong, Olaleye Omonike, and Huan Xie, “Formulation Development and pharmacokinetics of OJT001 Loaded Solid Lipid Nanoparticles,” in American Association of Pharmaceutical Sciences, AAPS, (Washington), Walter E. Washington Convention Center, Nov 6, 2018. 5. Xiuqing Gao, Hunter Hardy, Huan Xie, “Development of OJT001 Loaded Solid Lipid Nanoparticles,” in Research Centers in Minority Institutions, RCMI, (Washington), Marriott Wardman Park Hotel, Oct 30, 2017. 6. Guijin Lu, Xiuqing Gao, Zhiyong Wang, Yuan Chen, Huan Xie, Xiaohong Bi, “Targeted Imaging with Surface Enhanced Raman Spectroscopy”, in NanoX Mini-Symposium by Gulf Coast Consortia for Quantitative Biomedical Sciences, (Houston), BioScience Research Collarborative Event Hall at Rice University, Oct 04, 2016.

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