Assistant Professor Cancer Research

Location:

Posted:

August 19, 2024

Resume:

Assistant Professor of Hematology with extensive research experience in the academic, laboratory, and industries. Specialization in Molecular Hematology, Cell Biology, and Cancer Research. Many years of experience in teaching and research have sharpened my skills in diverse molecular and cell biology, including gene expression using Microarray, NGS, and real-time, as well as protein analysis using Western blot and Jess assay. Therefore, I can design and manage innovation with knowledge of various research methods and techniques. Expert in applying for and securing prestigious research grants. Effective instructor and supervisor to undergraduate, master-, and doctoral-level students. Author of numerous publications in high-impact scientific journals. Organized and detail-oriented with excellent analytical thinking and problem-solving skills. Native Arabic and fluent in English. Areas of Expertise

General Research Management: Molecular Hematology Research: Biomedical science Industry: Scientific Research and Studies

Grants.

Mechanism of Resistance to Tyrosine

Kinase Inhibitors.

Hematology laboratories for

conducting various tests and

analysis of blood samples.

Project Design and

Management Lab Experiments

and Tests.

The Effect Mechanism of Thymoquinone

on Leukemia.

Diagnosis and treatment of various

blood-related diseases.

Lab Technologies and

Instruments Research Team

Leadership.

Prognostic Markers and Therapeutic

Targets in Thalassemia Patients.

Blood Transfusions.

Searching and development of

medications and therapies for

various blood disorders.

Summary of Skills

Eight years of teaching and research experience in School of Biomedicine, Faculty of Health Sciences, University of Sultan Zainal Abidin, Terengganu, Malaysia.

Experienced in planning course syllabus and assessing the students' progress. Good network with professionals in the molecular ﬁeld. Skilled in building collaboraQons with industry and seeking funds. Skilled in providing advice and guiding under- and post-graduate students for the academic progress. Education

Doctor of Philosophy in Molecular Hematology Molecular and Cytogene>c of Myeloid Leukemia, 2015 Faculty of Medicine UniversiQ Sains Malaysia (USM), Kubang Kerian, Kelantan, Malaysia Disserta(on: “In-Vitro Study of Resistance to Tyrosine Kinase Inhibitors on JAK/STAT 1, 3 and 5 Signaling Pathways in Myeloid Leukemia”.

Master of Science in Transfusion Science, 2009

Advanced Medical and Dental Institute (AMDI) Universiti Sains Malaysia (USM), Pulau Pinang, Malaysia Bachelor of Medical Laboratories, 1998

Faculty of Medicine Sana’a University, Yemen

Industry Experience

Medical Laboratories Several Hospitals in Malaysia

• Guide students to perform their practical in medical laboratories in different Hospitals.

• Supervise the student and assisting their performance along with medical laboratories’ staff in the respective hospitals.

• Counselling the students to select their topics for final year projects. Bossier, LA, United States •+1-318-***-****

**************@*****.***

Hamid Ali Nagi Al-Jamal

Research Scientist Research Associate

Senior Lecturer

• Supervise the students to perform their projects in the respective hospitals and institutions. Laboratory Technician Medical Laboratories Al-Thawrah General Hospital/ Ibb Branch, Yemen

• Carried out diverse hematological and blood transfusion analyses.

• Conducted biochemical, microbiological, and parasitological analysis. Consultant in Medical Laboratory (part Qme/ Almajd Specialized Hospital, Ibb, Yemen

• Consulting and managing the medical laboratories.

• Trained and built the capacity of the laboratory staff to evaluate and interpret clinical analysis. Academic Experience

Faculty of Health Sciences Universiti Sultan Zainal Abidin (UniSZA), Terengganu, Malaysia June 1st, 2016 – May 31st, 2024 Senior Lecturer

• Instruct and coordinate undergraduate courses on Hematology subjects.

• Teaching theoretical and practical undergraduate courses in Transfusion Science & Blood Banking.

• Timely assess the students’ progress and provide the students with necessary counseling.

• Contribute in the curriculum development for Biomedicine and Medical Laboratory Technology (MLT) programs.

• Coordinator for Hematology and Transfusion Science & Blood Banking for MLT and Biomedicine students.

• Mentor master- and doctoral-level students in research projects, review proposals and theses and supervise research activities.

• Supervise undergraduate students in literature research, research projects, and lab practical.

• Apply for and manage university, national, and international research grants. High Medical Institute Ibb branch/ Ministry of Health), Yemen 2002 – 2007 Lecturer

• Instructed theoretical and practical undergraduate courses in Medical Microbiology, Hematology, and Blood Transfusion.

• Served as a member of the Examination Committee.

• Supervised research projects conducted by students.

• Provided counseling and technical expertise in planning and conducting research projects. Current and past related research projects

Faculty of Health Sciences Universiti Sultan Zainal Abidin (UniSZA), Terengganu, Malaysia 2016 –2024 Senior Lecturer

• Elucidate the Effect Mechanism of Thymoquinone on STAT and PI3/Akt Signaling in Animal Models with Chronic Myeloid Leukemia.

• Molecular Characterization of HBB Gene Mutation in Hemoglobin E/β-Thalassemia Patients and the Effects of the Disease on Genes Expression Related to Iron Metabolism.

• Deciphering The Effect Mechanism of Thymoquinone on JAK/STAT Signaling Negative Regulation in Myeloid Leukemia Cells.

• Elucidate the Therapeutic impact of Thymoquinone on c-Myc oncogene in acute myeloid leukemia cell line.

• Comprehensive Bioinformatics Analysis of Transcriptome Profiling in Regulating Population Genetic Structure of Beta- thalassemia in Malaysia

Hamid Ali Nagi Al-Jamal

• Effect of Weight Loss on Iron Status Among Overweight and Obese Young Women with Iron Deficiency Anemia.

• Antibacterial and Antibiofilm Activities of Malaysian Trigona Honey Against Pseudomonas Aeruginosa and Streptococcus Pyogenes

Internal and External Committee Membership

• ScienQﬁc Commijee Member in InternaQonal Cardiovascular and Metabolic Health Conference 2023, (COMET 2023), Laguna Redang Island Resort 10-12 October 2023, Terengganu, Malaysia. Faculty of Health Sciences, UniversiQ Sultan Zainal Abidin (UniSZA).

• Editorial board member in Experimental and TherapeuQc Medicine (SPANDIDOS) since Feb. 2023 Qll present

(hjps://bit.ly/3Q7h47x).

• Editorial board member in SF Journal of Blood Medicine and Research 2022-present (hjps://bit.ly/3FcWA6U).

• Malaysian Blood Transfusion Society (MBTS), LifeQme Membership (since 10th November 2022).

• Graduate Management Commijee Member in Faculty of Health Sciences, Sultan Zainal Abidin University, 01Jan 2022- 31 Dec 2023.

• Human Research Ethics Commijee (UHREC) in Sultan Zainal Abidin University, 01Jan 2022- 31 Dec 2023.

• Malaysian Society of Hematology 15 August 2019-14 July 2029.

• Members of Malaysian Laboratory Haematology Society (MMLHS), LifeQme Membership (since 14 April 2019).

• Editorial board member in Journal of Cancer Treatment and Research, Nov 2018-2020.

• Editorial board member of Austin Leukemia Journal, April 2017-present.

• Editorial board, Austin Hematology Journal, 2015-present.

• International Society for Laboratory Hematology, 2015-May 2019. Honors & Awards

1. Staff Excellence Award 2022 (High Impact publication Award 2023), Universiti Sultan Zainal Abidin, Awarded on February 2024.

2. Excellence Research and innovation Award 2023 with External Research Grant commitment for 2023, Universiti Sultan Zainal Abidin, Awarded in February 2024.

3. University Excellence Service Award 2022, Human Resource Development Panel of Universiti Sultan Zainal Abidin, Awarded; 14/12/2023.

4. Staff Excellence Award 2022 (High Impact publication Award 2023), Universiti Sultan Zainal Abidin, Awarded on 14 December 2023.

5. Staff Excellence Award 2021 (High Impact publication Award 2021), Universiti Sultan Zainal Abidin, Awarded on 13 September 2022.

6. University Excellence Service Award for 2020, Human Resource Development Panel of Universiti Sultan Zainal Abidin, Awarded; 17/10/2021.

7. Wan Rohani Binti Wan Taib, Imilia Ismail, Hamid Ali Al-Jamal, Mohd Khalid Awang Nur Aisyah Aziz, Ezalia Esa, Hishamshah Mohd Ibrahim, SILVER MEDAL AWARD, Week of Research and Innovation, Universiti Terengganu Malaysia (UMT), on a project entitled: MYTHALAHAP: A Risk Prediction Model, Online, 10 Mar 2021. 8. The 2nd prize winner of the laboratory poster competition In the 17th Malaysian Society of Haematology Scientific Meeting, Held on 10th -12th September 2020, Shangri La Hotel, Kuala Lumpur, Malaysia. 9. University Excellence Service Award for 2019, Human Resource Development Panel, Universiti Sultan Zainal Abidin. 10. University Excellence Service Award for 2018, Human Resource Development Panel, Universiti Sultan Zainal Abidin. 11. The 1st prize, Outstanding Poster Award

“RestoraQon of PRG2 expression by 5-azacyQdine confers sensiQvity in Midostaurin resistant AML cells, 11th Malaysian NaQonal Haematology ScienQﬁc MeeQng, 4th to 6th April 2014, Shangri La Hotel, Kuala Lumpur, Malaysia. Hamid Ali Nagi Al-Jamal

Grants & Funding

4 Research grants as Principal Inves(gator, 4 research grants as Co-Inves(gator, full details available upon request. Publications

26 publica(ons as First/Corresponding Author, 22 publica(ons as Co-Author, full details available upon request Postgraduate Supervision

SPECIAL INVITATIONS/APPOINTMENTS

1. Journals Reviewer

1) BMC Medical Genomics.

2) Hematology.

3) Oncology Letters.

4) Bioengineered.

5) Oncology Reports.

6) Molecular Medicine Reports.

7) Molecular and Clinical Oncology.

8) International Journal of Oncology.

9) Experimental and Therapeutic Medicine.

10) Integrative Cancer Therapies Journal.

11) International Journal of Molecular Medicine.

2. Contribute to Evaluation of University Grant Application (DPU grant). 3. Served as a member of the Examination Committee for postgraduate students. 4. Contribute to the evaluation of postgraduate students' proposal defense. 5. Contribute to the evaluation of postgraduate students' proposal defense. 6. Contribute to evaluating students’ proposal presentations for Final Year Research Project. 7. Served as a Judge for evaluation of oral presentations in Global Health Sciences Conferences 2020 (GHSC 2020). Pandemic Challenges in Health Sustainability, 12 December 2020. Conferences & Presentations

35 conferences and presenta(ons, full details available upon request. Portfolio

Program Status Main

Supervisor

Co-

Supervisor

PhD Graduated 3 1

Ongoing 0 2

Masters Graduated - -

Ongoing 1 -

Final Year

Project

Graduated 14 1

Ongoing 2 -

LinkedIn Google Scholar

Web of Science ORCID

Scopus ResearchGate

Hamid Ali Nagi Al-Jamal

Skills Summary

Experience Knowledgeable in maintaining cell lines and primary cultures for various analysis.

Expert in developing leukemia-resistant cell

lines to tyrosine kinase inhibitors.

Knowledgeable about apoptosis and cell

cycle assays analysis using ﬂowcytometry.

Familiar and perform cell viability and

cytotoxic assay analysis using diﬀerent kits

such as MTT, MTS, and cell counQng WST-8

assay.

IsolaQon and puriﬁcaQon of DNA/RNA and

proteins from various sources, such as cells

and animal Qssues.

Design primers and perform PCR reacQons to

amplify speciﬁc DNA/RNA sequences.

Running agarose or polyacrylamide gel electrophoresis to separate DNA/RNA, and Proteins for respecQve analysis. knowledgeable about sequencing analysis such as Sanger sequencing, pyrosequencing, and Next-generaQon

sequencing (NGS) technologies, which used to determine the nucleoQde sequence of DNA and RNA molecules.

Expert in analyzing gene expression levels in diﬀerent biological samples using techniques such RT-PCR (reverse transcripQon PCR) and quanQtaQve real-Qme PCR (qPCR), or gene expression proﬁling using microarray.

Expert in other protein analysis using Western blot and Jess assay to evaluate many signaling pathways such as and NOT limited to JAK/STAT and PI3/Akt signaling pathways. Design and conduct molecular experimental research to invesQgate speciﬁc biological enQQes and contribute to the scienQﬁc research in the ﬁeld of molecular biology and cancer research.

LIST OF PUBLICATIONS, GRANTS & OTHERS

PUBLICATIONS

AS A FIRST/CORRESPONDING AUTHOR

No. TILTE

Cite

score

2022

WoS IF

2022

Alhawamdeh, M., Almajali, B., Hourani, W., Al-Jamal, H.A., Al-Wajeeh, A.S., Mwaﬁ, N.R. ... Tarawneh, I.A. (2024). Eﬀect of IFN-γ encapsulated liposomes on major signal transducLon pathways in the lymphocytes of paLents with lung cancer. Oncology LePers, 27, 8. hPps://doi.org/10.3892/ol.2023.14141

6.3 2.9

2. 1

Alamro M. A, Ahmed K. A, Khleifat K. M, Almajali B, Sayed U, Al-wajeeh A. S, Al-Jamal H. A. N.,

(2024). Lipoprotein-Associated Phospholipase A2 and hs-CRP are Correlated with AnL-TPO AnLbodies in Jordanian Non-Pregnant Women with Hashimoto’s ThyroidiLs. Biomedical and Pharmacology Journal, 17(2). hPps://dx.doi.org/10.13005/bpj/293 3. 2

Al-Rawashde, F. A., Al-Sanabra, O. M., Alqaraleh, M., Jaradat, A. Q., Al-Wajeeh, A. S., Johan, M. F., Wan Taib, W. R., Ismail, I., & Al-Jamal, H. A. N. (2023). Thymoquinone Enhances Apoptosis of K562 Chronic Myeloid Leukemia Cells through Hypomethylation of SHP-1 and Inhibition of JAK/STAT Signaling Pathway. Pharmaceuticals, 16(6), 884. https://doi.org/10.3390/ph16060884

4.7 4.6

4. 3

Saad HKM, Taib WRW, Ab Ghani AS, Ismail I, Al-Rawashde FA, Almajali B, Alhawamdeh M, Abd Rahman AA, Al-wajeeh AS, Al-Jamal HAN (2023). HBB Gene Mutations and Their Pathological Impacts on HbE/β-Thalassaemia in Kuala Terengganu, Malaysia. Diagnostics. 13(7):1247. https://doi.org/10.3390/diagnostics13071247.

3.6 3.6

Hamid Ali Nagi Al-Jamal

5. 4

Al-Rawashde, F. A., Al-wajeeh, A. S., Vishkaei, M. N., Saad, H. K. M., Johan, M. F., Taib, W. R. W., Ismail, I., & Al-Jamal, H. A. N. (2022). Thymoquinone Inhibits JAK/STAT and PI3K/Akt/ mTOR Signaling Pathways in MV4-11 and K562 Myeloid Leukemia Cells. Pharmaceuticals, 15(9), 1123. https://doi.org/10.3390/ph15091123.

4.7 5.2

6. 5

Almajali, B., Johan, M. F., Al-Wajeeh, A. S., Wan Taib, W. R., Ismail, I., Alhawamdeh, M., Al- Tawarah, N. M., Ibrahim, W. N., Al-Rawashde, F. A., & Al-Jamal*, H. A. N. (2022). Gene Expression Profiling and Protein Analysis Reveal Suppression of the C-Myc Oncogene and Inhibition JAK/STAT and PI3K/AKT/mTOR Signaling by Thymoquinone in Acute Myeloid Leukemia Cells. Pharmaceuticals, 15(3), 307. https://doi.org/10.3390/ph15030307. 4.7 5.2

7. 6

Saad, H. K. M., Abd Rahman, A. A., binL Ab Ghani, A. S., Taib, W. R. W., Ismail, I., Johan, M. F., Al-Jamal*, H. A. N. (2022). AcLvaLon of STAT and SMAD Signaling Induces Hepcidin Re- Expression as a TherapeuLc Target for β-Thalassemia PaLents. Biomedicines, 10(1), 189. http://doi:10.3390/biomedicines10010189.

3.7 4.7

8. 7

Alkafaween, M., Abu-Sini, M., & Al-Jamal, H. (2022). Antibiotic Susceptibility and Differential expression of virulence genes in Staphylococcus aureus. Applied Environmental Biotechnology, 7(1), 6-15. doi:http://dx.doi.org/10.26789/AEB.2022.01.002. 1.1 2.02

9. 8

Al-Kafaween, M. A., & Nagi Al-Jamal, H. A. (2022). A comparative study of antibacterial and antivirulence activities of four selected honeys to Manuka honey. Iranian journal of microbiology, 14(2), 238–251. https://doi.org/10.18502/ijm.v14i2.9193. 2.2 1.4

10. 9

Al-Kafaween MA, Al-Jamal* HAN, Hilmi AB. De Novo Whole Genome Sequencing Data of Pseudomonas aeruginosa ATCC10145, an Opportunistic Pathogen. Trop J Nat Prod Res. 2022; 6(2):176-179.

0.16 0.6

(Scopus)

11. 1

Al-Rawashde, F. A., Johan, M. F., Taib, W. R. W., Ismail, I., Johari, S. A. T. T., Almajali, B., … Al- Jamal*, H. A. N. (2021). Thymoquinone Inhibits Growth of Acute Myeloid Leukemia Cells through Reversal SHP-1 and SOCS-3 Hypermethylation: In Vitro and In Silico Evaluation. Pharmaceuticals, 14(12), 1287. https://doi.org/10.3390/ph14121287. 4.7 5.2

12. 1

Al-Rawashde FA, Wan Taib WR, Ismail I, Johan MF, Al-Wajeeh AS, Al-Jamal* HAN. Thymoquinone Induces Downregulation of BCR-ABL/JAK/STAT Pathway and Apoptosis in K562 Leukemia Cells. Asian Pac J Cancer Prev. 2021 Dec 1;22(12):3959-3965. DOI: 10.31557/APJCP.2021.22.12.3959.

0.42 1.89

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13. 1

A. Alkafaween, M., Magharbeh, M., Khleifat, K., Saraireh, R., Qaralleh, H., El-Hasan, T., Hujran, T., Jarrah, N., Al-Tarawneh, A., H. Ajbour, S., O. Al-limoun, M., Alqaraleh, M., Al- Jamal*, H., & Amonov, M. (2021). Biodegradation of Phenol by Bacillus simplex: Characterization and Kinetics Study. Applied Environmental Biotechnology, 6(2), 1-12. doi:http://dx.doi.org/10.26789/AEB.2021.02.001.

1.1 2.02

14. Saad, H.K., Taib, W.R., Ismail, I., Johan, M.F., Al-Wajeeh, A.S., & Al-jamal*, H.A. (2021). Reduced hepcidin expression enhances iron overload in patients with HbE/β-thalassemia: Α comparative cross-sectional study. Experimental and Therapeutic Medicine, 22, 1402. https://doi.org/10.3892/etm.2021.10838.

6 2.75

15. Alshwaiyat, N.M., Ahmad, A., Wan Hassan, W., & Al-Jamal*, H.A. (2021). Association between obesity and iron deficiency (Review). Experimental and Therapeutic Medicine, 22, 1268. https://doi.org/10.3892/etm.2021.10703.

6 2.75

16. Almajali, B., Al-Jamal*, H., Taib, W., Ismail, I., Johan, M. F., Doolaanea, A. A., & Ibrahim, W. N.

(2021). Thymoquinone, as a Novel Therapeutic Candidate of Cancers. Pharmaceuticals,14(4), 369. https://doi.org/10.3390/ph14040369.

4.7 5.2

Hamid Ali Nagi Al-Jamal

17. Almajali, B., Al-Jamal*, H., Wan Taib, W. R., Ismail, I., Johan, M. F., Doolaanea, A. A., Ibrahim, W. N., & Tajudin, S. A. (2021). Thymoquinone Suppresses Cell Proliferation and Enhances Apoptosis of HL60 Leukemia Cells through Re-Expression of JAK/STAT Negative Regulators. Asian Pacific journal of cancer prevention: APJCP, 22(3), 879–885. https://doi.org/10.31557/APJCP.2021.22.3.879.

0.42 1.89

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18. Mohammad A. Al-kafaween, Abu Bakar Mohd Hilmi, Hamid A. Nagi Al-Jamal*, Rania M. Al- Groom, Nour A. Elsahoryi, and Hiba Al-Sayyed, (2021). “Potential Antibacterial Activity of Yemeni Sidr Honey Against Pseudomonas aeruginosa and Streptococcus pyogenes,” Anti- Infective Agents; 19(4): e130621192336.

0.766 1.2

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19. Alkafaween, M. A., Al-Jamal, H. A. N., & Hilmi, A. B. M. (2021). EvaluaLon of anLmicrobial and anLbioﬁlm acLviLes of sLngless bee Trigona honey (Malaysia) against Streptococcus pneumoniae. The InternaHonal Arabic Journal of AnHmicrobial Agents, 11(2). https://doi.org/10.3823/856.

20. Alkafaween, Mohammad A.; AL-JAMAL, Hamid A. Nagi; MOHMD HILMI, Abu Bakar (2021). AnLbacterial acLvity of selected varieLes of Malaysian honey against Escherichia coli: A comparaLve study. The InternaHonal Arabic Journal of AnHmicrobial Agents, 11 (1). https://doi.org/10.3823/854.

21. Al-Kafaween MA, Al-Jamal* HAN, Hilmi ABM, Elsahoryi NA, Jaffar N, Zahri MK. Antibacterial properties of selected Malaysian Tualang honey against Pseudomonas aeruginosa and Streptococcus pyogenes. Iran J Microbiol. 2020;12(6):565-576. doi:10.18502/ijm.v12i6.5031.

2.2 1.4

22. Al-Jamal, H. A. N., Johan, M. F., Mat Jusoh, S. A., Ismail, I., & Wan Taib, W. R. (2018). Re- Expression of Bone Marrow Proteoglycan-2 by 5-Azacytidine is associated with STAT3 Inactivation and Sensitivity Response to Imatinib in Resistant CML Cells. Asian Pacific Journal of Cancer Prevention, 19(6): 1585-1590.

0.42 1.89

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23. Al-Jamal, H. A, Asma’a, M. J., Hassan, R. & Johan, M.F. (2015). Enhancing SHP-1 expression with 5-azacytidine may inhibit STAT3 activation and confer sensitivity in lestaurtinib (CEP- 701)-resistant FLT3-ITD positive acute myeloid leukemia. BMC Cancer, 15:869. 5.4 3.8

24. Al-Jamal H, Jusoh S, Sidek M, Hassan, R. & Johan, M. F. (2015). Restoration of PRG2 Expression by 5-Azacytidine Involves in Sensitivity of PKC-412 (Midostaurin) Resistant FLT3-ITD Positive Acute Myeloid Leukaemia Cells. J Hematol Thrombo Dis, 3(186), 2. 4.9 2.67

25. Al-Jamal, H. A., Jusoh, S. A., Yong, A. C., Asan, J. M., Hassan, R. & Johan, M. F. (2014). Silencing of suppressor of cytokine signaling-3 due to methylation results in phosphorylation of STAT3 in imatinib resistant BCR-ABL positive chronic myeloid leukemia cells. Asian Pac J Cancer Prev, 15(11), 4555-61.

0.42 1.89

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AS A CO-AUTHOR

1. Al-Rawashde, F. A., Alqaraleh, M., Alhmoud, J. F., Al-Sanabra, O. M., Saad, H. K. M., Odat, N.,

... & Nagi Al-Jamal, H. A. (2024). In silico EvaluaLon of the AnLleukemia AcLviLes of Thymoquinone by TargeLng FLT3-ITD and BCR-ABL Signaling in Myeloid leukemia. Tropical Journal of Natural Product Research, 8(6). 10.26538/tjnpr/v8i6.17 Scopus

2. Ismail, N. H., Mussa, A., Al-Khreisat, M. J., Mohamed Yusoﬀ, S., Husin, A., Al-Jamal, H. A. N., Johan, M. F., & Islam, M. A. (2023). DysregulaLon of Non-Coding RNAs: Roles of miRNAs and lncRNAs in the Pathogenesis of MulLple Myeloma. Non-Coding RNA, 9(6), 68. hPps://doi.org/10.3390/ncrna9060068

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Hamid Ali Nagi Al-Jamal

3. Alshwaiyat NM, Ahmad A and Al-Jamal HAN (2023). Eﬀect of diet-induced weight loss on iron status and its markers among young women with overweight/obesity and iron deﬁciency anemia: a randomized controlled trial. Front. Nutr. 10:1155947. doi: 10.3389/fnut.2023.1155947.

3.5 4

4. MA Al-Kafaween, ABM Hilmi, HAN Al-Jamal (2022). Physicochemical and Therapeutic Properties of Malaysian Stingless Bee Kelulut Honey in Comparison with Yemeni Sidr Honey. Anti-Infective Agents, 20 (5), 150-159.

0.766 1.2

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5. KM Khleifat, MM Khalil, MA Al-kafaween, M Alqaraleh, MO Al-limoun, ... Hamid A Nagi Al- Jamal (2022). Studying the relationship between women hormonal activity and the distribution of bacterial vaginosis and bacteria’s antibiotics susceptibility. Journal of Applied Pharmaceutical Science, 12 (12): 105-116.

2.4 1.47

6. AlFaris NA, Alshwaiyat NM, AlTamimi JZ, Alagal RI, Al-Jamal HA, and AlKehayez NM (2022). Physical AcHvity Levels of a MulH-Ethnic PopulaHon of Middle-Aged Men Living in Saudi Arabia and Factors Associated With Physical InacHvity. Int J Public Health 66: h[ps://doi.org/10.3389/ijph.2021.1604328

5 4.5

7. AlTamimi JZ, Alagal RI, AlKehayez NM, Alshwaiyat NM, Al-Jamal HA, and AlFaris NA (2022). Physical AcHvity Levels of a MulH-Ethnic PopulaHon of Young Men Living in Saudi Arabia and Factors Associated With Physical InacHvity. Front. Public Health 9:734968. DOI: h[ps://doi.org/10.3389/fpubh.2021.734968

5 4.5

8. Aziz, NA., Taib, WR.W., Kharolazaman, NK. Ismail, I., Al-Jamal, HAN, et al. Evidence of new intragenic HBB haplotypes model for the predicLon of beta-thalassemia in the Malaysian populaLon. Sci Rep 11, 16772 (2021). hPps://doi.org/10.1038/s41598-021-96018-y 4.6

9. Zakaria, N. A., Rosle, N. A., SiL Asmaa, M. J., Aziee, S., Haiyuni, M. Y., Samat, N. A., Husin, A., Hassan, R., Ramli, M., Mohamed Yusoﬀ, S., Ibrahim, I. K., Al-Jamal, H., & Johan, M. F. (2021). ConformaLon sensiLve gel electrophoresis for the detecLon of calreLculin mutaLons in BCR- ABL1-negaLve myeloproliferaLve neoplasms. InternaHonal journal of laboratory hematology, 43(6), 1451–1457. hPps://doi.org/10.1111/ijlh.13628. 4.10 3

10. Al-kafaween, M. A., Hilmi, A. B. M., & Al-Jamal, H. A. N. (2021). The Beneﬁcial Eﬀects of SLngless Bee Kelulut Honey against Pseudomonas aeruginosa and Streptococcus pyogenes Planktonic and Bioﬁlm: Doi. org/10.26538/tjnpr/v5i10. 15. Tropical Journal of Natural Product Research (TJNPR), 5(10), 1788-1796.

11. Mohammad Al-kafaween, Abu Bakar Hilmi, Hamid Al-Jamal, Norzawani Jaffar, Hiba Al- Sayyed, Mohd Zahri (2021). Effects of selected Malaysian Kelulut Honey on biofilm formation and the gene expression profile of Staphylococcus Aureus, Pseudomonas Aeruginosa and Escherichia Coli. Jordan Journal of Pharmaceutical Sciences, 14 (1): 9-25. 1.12

12. Mat Jusoh, Al-Jamal, H. A., Hussein A. R., Yahaya BH, Husin A, Hassan, R., Hussain FA, Shaharum Shamsuddin, Johan, M. F. (2020). Transcriptomic Profiles of MV4-11 and Kasumi 1 Acute Myeloid Leukemia Cell Lines Modulated by Epigenetic Modifiers Trichostatin A and 5- Azacytidine. International Journal of Hematology-Oncology and Stem Cell Research, 14(1): 72– 92.

0.66

13. Al-Kafaween M, Mohd Hilmi AB, Al-Jamal H, A., Elsahoryi N, Jaﬀar N, Khairi Zahri M.,

(2020). Pseudomonas Aeruginosa and Streptococcus Pyogenes Exposed to Malaysian Trigona Honey In Vitro Demonstrated DownregulaHon of Virulence Factor. Iran J Biotechnol,18(4):e2542.

1.3

Hamid Ali Nagi Al-Jamal

CONFERENCE PAPERS

1. Saad HKM, Al-wajeeh AS., ABD Rahamn, AA., AB Ab Ghani AS, Taib WRW, Ismail I, Johan, MF, Al-Jamal HAN

(Accepted). Transferrin gene expression as a biomarker of ineffective erythropoiesis and iron overload in HBE/β- thalassemia and β-thalassemia trait patients. 3rd International Postgraduate research Conference 2022, Dewan Perdana, UniSZA.

2. Al-Jamal HA, WRW Taib, SA Mat Jusoh, A. Sudin and MF. Johan (2017). Azacytidine enhances sensitivity response to imatinib in BCR/ABL positive CML cell line. Global Globin 2020 challenges (GG2020) Conference, Impiana KLCC Hotel, Kuala Lumpur, Malaysia, PP 20-22.

3. Johan, M. F. & Al-Jamal, H. A. (2013). Restoration of SHP-1 Expression by 5-Azacytidine Confer Sensitivity in Imatinib- Resistant BCR-ABL Chronic Myeloid Leukaemia. Proceedings of the 10th Malaysia Genetics Congress, Advances in Genetics, Biotechnology and Genomics, Palm Garden Hotel IOI Resort, Putrajaya, Malaysia, pp. 235-39. 14. Al-Kafaween MA, Hilmi ABM, Jaffar N, Al-Jamal HAN, Zahri MK,et al., (2020). Effects of Trigona honey on the Gene Expression Profile of Pseudomonas aeruginosa ATCC 10145 and Streptococcus pyogenes ATCC 19615. Jordan Journal of Biological Sciences, 13 (2): 133-138. 0.29

15. Al-Kafaween MA, Hilmi ABM, Jaffar N, Al-Jamal HAN, Zahri MK, Jibril.F.I., (2020). Antibacterial and Antibiofilm Activities of Malaysian Trigona Honey Against Pseudomonas Aeruginosa ATCC 10145 and Streptococcus Pyogenes ATCC 19615. Jordan Journal of Biological Sciences, 13 (1): 69 –76.

0.29

16. Al-kafaween, M.A., Mohd Hilmi, A.B., Jaffar, N., Al-Jamal H.A.N., Zahri, M.K., (2019). Determination of optimum incubation time for formation of Pseudomonas aeruginosa and Streptococcus pyogenesbiofilms in microtiter plate. Bull Natl Res Cent 43, 100. 17. Aziee, S., Haiyuni, M. Y., Al-Jamal, H. A. N., Shafini, M. Y., Wahab, R. A., Shamsuddin, S., & Johan, M. F. (2018). Apoptotic Induction in CCRF-CEM and HL-60 Human Leukemic Cell Lines by 5-Azacitidine and Trichostatin A. Journal of Biomedical and Clinical Sciences (JBCS), 3(1), 54-61.

18. Ismail, I., Sulong, S., Al Jamal, H. A, Johan, M. F., & Hassan, R. (2018). Differential expression profiles of miRNAs and correlation with clinical outcomes in acute myeloid leukemia. Meta Gene. 16: 182-188.

0.9 0.2

19. Zamani, A., Jusoh, S. A. M., Al-Jamal, H. A, Sul’ain, M. D. & Johan, M. F. (2016). Anti- Proliferative Effects of Dendrophthoe pentandra Methanol Extract on BCR/ABL-Positive and Imatinib-Resistant Leukemia Cell Lines. Asian Pac J Cancer Prev, 17 (11), 4857-4861. 0.42 1.89

(Scopus)

20. Yunus, N. M., Johan, M. F., Al-Jamal, H. A., Husin, A., Hussein, A. R. & Hassan, R. (2015). Characterisation and clinical significance of FLT3- ITD and non-ITD in acute myeloid leukaemia

(AML) patients in Kelantan, Northeast of Peninsular Malaysia. Asian Pac J Cancer Prev, 16: 4869-72

0.42 1.89

(Scopus)

21. Asma’a, M. J., Al-Jamal, H. A., Seeni, A. & Johan, M. F. (2015). Growth inhibitory effects of crude pomegranate peel extract on chronic myeloid leukaemia, K562 cells. Int J App Basic Med Res, 5:98-103.

1.1

22. Jusoh, S. A., Al-Jamal, H. A., Ang, C. Y., Asan, J. M., Seeni, A. & Johan, M. F. (2014). Apoptosis induction in MV4-11 and K562 human leukemic cells by Pereskia sacharosa (Cactaceae) leaf crude extract. Asian Pac J Cancer Prev, 15(1), 475-81 0.42 1.89

(Scopus)

23.

Kamil, M., Al-Jamal, H. A. & Yusoff, N. M. (2010). Association of ABO blood groups with diabetes mellitus. Libyan J Med, 5 (1), 4847.

2.6 1.74

Hamid Ali Nagi Al-Jamal

BOOK CHAPTERS

1. Belal Almajali, Abdullah Saleh Al-wajeeh, Hamid Ali Nagi Al-Jamal* (2022). “Thymoquinone in Cancers Therapy”. Updates in Pharmacology. Vide Leaf.

2. Roheen Akbar.; Faheem M.; Hamid Ali Nagi Al-Jamal. (2021). [CHAPTER 3_ALU PCR], [Polymerase Chain Reaction: Types and Applications], AMAZON; pp:22-24. ISBN-13: 979-8721812033. 3. Aye sha A.B.; Faheem M.; Muhammad H.; Hamid Ali Nagi Al-Jamal.; Fizah I. (2021). [CHAPTER 5_ASYMMETRIC PCR],

[Polymerase Chain Reaction: Types and Applications], AMAZON; pp:22-24. ISBN-13: 979-8721812033. 4. Ayesha R; Faheem M.; Muhammad H.; Mubbashar M.; Hamid Ali Nagi Al-Jamal. (2021). [CHAPTER 6_COLD-PCR],

[Polymerase Chain Reaction: Types and Applications], AMAZON; pp:22-24. ISBN-13: 979-8721812033. 5. Maheen Z.; Faheem M.; Muhammad H.; Zirwah Tahir.; Hamid Ali Nagi Al-Jamal. (2021). [CHAPTER 7_ COLONY PCR],

[Polymerase Chain Reaction: Types and Applications], AMAZON; pp:22-24. ISBN-13: 979-8721812033. BOOKS

[“Acute Myeloid Leukemia: Current Therapy, Challenges, and Future Therapeutic Candidates]”, [B P International], [2023]

[Hamid Ali Nagi Al-Jamal, Belal Almajali, Maysa Alhawamdeh, Hanan Kamel M. Saad]. RESEARCH GRANTS

Principal Investigator

Title Amount (RM)

[US$1~RM4] Duration Funder& code

Elucidate the Effect Mechanism of Thymoquinone on STAT and PI3/Akt Signaling in Animal Models with Chronic Myeloid Leukemia

143,500-****-****

Malaysian Minister of

Higher EducaLon.

FRGS/1/2023/SKK10/UNIS

ZA/02/4

Elucidate the Effect Mechanism of SMADs and JAK/STAT Signalling Pathways on Iron Metabolism in HbE/β- thalassemia patients.

25,000-****-****

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