Bioinformatician / Data Manager

Ardit Mishra

Chicago, IL *****

773-***-**** • ***********@*****.***• https://github.com/Ardit-Mishra • linkedin.com/in/ardit-mishra EDUCATION

Loyola University Chicago, Chicago, IL 60660 August 2018 - December 2023

● Bachelor's Degree in Bioinformatics (GPA: 3.6), Graduated December 2023

● Relevant Coursework: Bioinformatics (Python, R), Data Structures and Algorithms for Informatics (Python), Advanced Biostatistics, Computational Biology (Python, R), Database Programming (SQL, Java, C++, R), Molecular Biology Lab WORK EXPERIENCE

4225 Giddings Inc. Chicago, Illinois. August 2018 - November 2021 Data Manager

● Implemented Clover POS, enhancing transaction speeds by 10%.

● Analyzed sales data with Excel, identifying trends that led to a 12% increase in sales of slow-moving items through targeted promotions.

● Established data backup and security protocols, ensuring zero data loss incidents during tenure.

● Worked closely with marketing, resulting in a 20% uptick in targeted promotions and a 5% increase in overall customer engagement

RESEARCH AND PROJECTS

RNA-Seq Analysis on Multiple Sclerosis & Sephin1 Treatment January 2023 - May 2023 Lead Bioinformatics Developer/Analyst

● Conducted a thorough exploration of Sephin1's potential as an MS treatment, leveraging the EAE Mouse Model using tools such as Python, R, FastQC (for quality checks), Kallisto (for RNA Seq quantification), Sleuth (for differential expression analysis), and WebGestalt (for gene set enrichment).

● Successfully designed and implemented a comprehensive data processing pipeline to analyze RNA Seq data from multiple experimental groups.

● Derived key insights from gene set enrichment analysis, identifying pivotal gene pathways influenced by Sephin1.

● Established evidence supporting Sephin1 as a promising therapeutic candidate for MS. ACE (Achieving College Excellence) Program Management System January 2023 - April 2023 Phase Leader & Database Developer

● Developed a digital platform to enhance the support structure for ACE, targeting first-generation and financially-challenged students.

● Leveraged Python and SQLAlchemy for backend integration, streamlining data retrieval and interactions.

● Established relational schemas to ensure data integrity across departments.Implemented a structured relational database, optimizing queries for efficient advising, mentoring, and event tracking.

● Delivered a comprehensive, seamless system that bolstered ACE program functionalities and improved overall user engagement.

Genome-Wide Association Study on Celiac Disease August 2022 - December 2022 Lead Researcher

● Conducted comprehensive research on Celiac disease, an autoimmune disorder affecting the digestive system.

● Identified LPP and IL12A-AS1 as potential significant genetic variants using LDSC, Manhattan, and Q-Q plots.

● Utilized the S-PrediXcan method to validate gene variants, examining changes in gene expression across blood and stomach tissues.

● Expanded understanding of genetic predisposing factors beyond the known 40%, offering new avenues for therapeutic research.

SKILLS

● Python, R, SQL, Numpy, Scikit-learn, TensorFlow, Keras, Data Analysis, Machine Learning, Linux, Unix, RNAseq, NGS, NCBI, ETL Pipeline, Biostatistics, Matlab, Database Management, Java, Research, Communication, Excel

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