Mark D. Johns, MBA, CISSP

** ****** **. ******, ** 02129

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A collaborative and influential technology executive with extensive experience developing best in class IT organizations. Creating effective IT vision, roadmaps, and departmental structure. Adept at designing and maintaining adherence to standards, policies, and procedures. Collaboration across functions, levels, and geographies to establish optimal IT services, solutions, and infrastructure. A trusted advisor to executive teams, Boards, and business leaders. Communication of opportunities and data driven implications of system selections, architectural decisions, security matters and regulatory challenges. My success is driven by my passion, customer-centric focus, team approach, and my dedication to efficiency. Including a solid business acumen and emotional intelligence for building and maintaining high-performance and highly engaged teams. Best known for enabling company growth and success through key IT strategy, leadership, and execution. CORE COMPETENCIES

• Global IT Operations

• Regulatory Compliance

• Strategy & Planning

• Enterprise Applications

• IT Security

• Datacenter Management

• Cloud Computing

• Project Management

• Global Team Management

PROFESSIONAL EXPERIENCE

Flagship Pioneering Cambridge, MA

Senior Director of Information Technology 2021 – Present Flagship Pioneering is a Venture Capital & Private Equity firm that conceives, creates, resources, and develops first-in-category life sciences companies. Since its launch in 2000, the firm has applied a hypothesis-driven innovation process to originate and foster more than 100 scientific ventures, resulting in over $30 billion in aggregate value. To date, Flagship is backed by >$4 billion of aggregate capital commitments. The Flagship ecosystem includes Moderna Therapeutics (NASDAQ: MRNA). Delivering IT leadership for multiple late-stage Flagship portfolio companies, with responsibility for business & lab systems, Data sciences, IT services, infrastructure, projects, security, and partner relationships. Providing oversight and execution of the Information Technology related launch and site onboarding of new portfolio companies, creating systems roadmaps to meet strategic and operations needs of the company, planning, coordination, delivery and change management for IT projects.

• Provide IT leadership, vision, and planning for four of Flagship’s late-stage biotech companies (minimum series B financing); Cellarity, Laronde: Endless RNA Therapeutics, Tessera Therapeutics and Generate Biosciences.

• Oversight of core IT infrastructure, services, and partners for the companies and sites.

• Site & portfolio company IT Leadership:

o Business systems IT: Collaborate with company stakeholders to define business systems roadmaps; including data management & security, to meet strategic and operational needs of each company. o Core IT: Responsible for implementation and operation of all site and company infrastructure, end user computing and lab systems.

o Data science: Responsible for the support and direction of data scientists in collaboration with the Chief Digital Officer.

o Operations: Responsible for overall IT process development, documentation & oversight, e.g., user, vendor & company onboarding, offboarding, end user support, lab support, and emergency management. IT-related communication and change management.

o Projects: Own the coordination, implementation and change management related to cross-Flagship Enterprise Projects, as well as company and site-specific projects. o Security: Implementation of Flagship digital security policies and coordination with CIO, CISO on implementation of security policies.

o Relationships: Responsible for developing productive and strong company end user, executive, internal stakeholder, as well as vendor, and partner relationships. Building connections and relationships across Flagship Pioneering Operations and Origination teams to meet strategic and operational needs of companies o Budget/Finance: Work with Flagship and/or company finance and contracts teams for all IT-related budget planning and ongoing financial management for companies and site(s) o Company buildouts: Management of the build out of G&A and data science functions and IT systems, including hiring IT leadership staff.

Mark D. Johns, MBA, CISSP

17 Walker St. Boston, MA 02129

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o Lead with hands-on technical project management for all cloud, infrastructure, enterprise applications, networking, and technical support services. Implement best practices for high-availability IT systems including governance, operations, compliance and change management.

o Development for IT initiatives: cost analysis, budgeting, RFx, vendor selection, negotiation, systems design and capacity planning.

o Project management, technical and hands-on leadership for IT team members and cross-functional employees. o Lead and manage IT teams including infrastructure, networking, enterprise application support, and third-party consultants.

o Provide guidance, training, and development for IT team employees. Manage relationships with 3rd party vendors. Major projects and accomplishments

• Lead the technology design, build, and move of a 9-story mixed use biotech building at Boynton Yards 101 South St. (lab/office, 290,000 sq. ft.) for Cellarity, Laronde: Endless RNA Therapeutics, Tessera Therapeutics and Generate Biosciences. o Designed the technology platform for all companies inhabiting Boynton Yards. o Full network design including Markley Fabric with 20Gbps AWS Direct Connect.

Moved Cellarity, Laronde, Tessera Therapeutics and Generate Biosciences into Boynton Yards. full project responsibility: pre-move, move, reestablishment of lab, science, and office productivity.

Virtual Reality innovation room for Generate Biosciences.

• Build out of internal IT function, hiring an IT Director and staff for Generate Biosciences. o Migrating Generate Biosciences IT systems out of the Flagship Ecosystem to stand alone, including ERP, HR IT systems, business and science systems to ensuring successful company launch.

• Leading the ERP migration for Tessera Therapeutics to NetSuite.

• Cybersecurity audits and remediation for each company. Establishment of on-going IT security programs. Heavy focus on our data scientists and AWS configuration.

SQZ Biotechnologies Watertown, MA

Head of IT / Director of IT 2019 – 2021

SQZ Biotech is a cell therapy company, utilizing the proprietary CellSqueeze® platform to develop a new generation of cell therapies. SQZ currently focuses on the development of novel treatments that leverage targeted immune modulation to impact oncology and autoimmune diseases.

• Provide IT leadership, vision, and planning with hands-on technical project management for all cloud, infrastructure, enterprise applications, networking, and technical support services.

• Champion and facilitate the business-focused partnership between IT and its internal/external stakeholders, working closely with business leaders to design and deliver technical solutions.

• Implement best practices for high-availability IT systems including governance, operations, compliance and change management.

• Development for IT initiatives: cost analysis, budgeting, RFQ, vendor selection, negotiation, systems design and capacity planning.

• Project management, technical and hands-on leadership for IT team members and cross-functional employees.

• Lead and manage IT teams including infrastructure, networking, enterprise application support, and third-party consultants.

• Provide guidance, training and development for IT team employees. Manage relationships with 3rd party vendors. Major projects and accomplishments

• Created a Sarbanes-Oxley compliance program to prepare for IPO. Cybersecurity risk assessment. Creation and management of a comprehensive IT security and compliance program; control and policy creation and implementation, SDLC, change management with annual external audits.

• Project management of a custom coded AWS clinical data warehouse with Spark on PostgreSQL.

• Patient tumor image data on S3. Utilizing AI for pattern recognition. Established BI reporting function using Tableau.

• Labguru Electronic Laboratory Notebook (ELN).

• Implemented Cadilus FP&A for Finance Planning and Analysis.

• Connected to NetSuite, FP&A Data warehouse built in Microsoft Azure.

• Lead the company from the startup stage through IPO NYSE:SQZ

• Implemented FloQast, accounting close management software that simplifies monthly close with and automated tie-outs.

• Elimination of Managed Service Provider and build out of internal IT team. Mark D. Johns, MBA, CISSP

17 Walker St. Boston, MA 02129

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o Saved the company $350,000/yr.

• PleaseReview Real-time Document Collaboration Software for Clinical.

• DocuSign, converted QA and QC departments paper-based SOPs to electronic version including Part 11 compliance.

• Implementation of Veeva Vault eTMF (on-going)

• Moved offices to a 60,000 square foot facility with 30,000 sq ft of lab space and ACF in Arsenal Yards.

• Implemented Greenhouse, Applicant Tracking System for Human Resources. o Integrated job board with company website. Used web hooks and APIs to automate onboarding procedures.

• Implemented Datto backup and disaster recovery. Instituted yearly disaster recovery testing.

• VMware Workforce ONE – AirWatch MDM, Managing and securing our mobile phone fleet.

• Jira Service Desk and Confluence. Implemented Jira as our Service Desk. Integrated with Slack for user communication.

• Implemented Kaseya RMM for remote support, software patching, inventory.

• SmartDeploy, implemented to automate imaging and software deployment for laptop fleet.

• Cisco Umbrella, DNS filtering for malware protection.

• Egnyte cloud file storage. Converted Windows file servers. Maintained existing drive mappings for seamless transition.

• Sophos Endpoint Protection with EDR. A powerful AI using deep learning to protect against malware, ransomware.

• Thermo Fisher Chromeleon Enterprise. Converted standalone Vanquish HPLCs to a centralized stored LIMS database.

• Upgraded Thermo Fisher Attune equipment to Windows 10 compliant controllers.

• Ubiqiti Unify. Deployed network switches and WAPs in new building.

• Zoom Room implementation for all conference rooms.

• Procurify procurement system. Connected to NetSuite for ease of use in procurement.

• TIBCO Spotfire with Rave EDC connector, Medidata, Parexel Winthrop Capital Boston, MA

Head of IT / Director of IT 2011 – 2019

Head of Information Technology for Winthrop Capital and its affiliates; Winthrop Management and First Winthrop Corporation.

• Acquisition of New York REIT (NYSE:NYRT) and integration of their IT systems. o The acquisition was a hostile take-over requiring a rapid facilitation of IT integration with little knowledge transfer from previous IT teams. Full integration of their IT systems and data was necessary in an extraordinarily tight timeline. o Achieved the project timeline goals of two months to integrate a complex ERP system and data transfer integration. o Passed a stringent 3rd party Sarbanes-Oxley audit from KPMG without an exception.

• Creation of a comprehensive business continuity and disaster recovery plan. o Converted hot site disaster recovery datacenter to Microsoft Azure Site Recovery (Disaster Recovery as a service, DRaaS) o Unitrends migration to Veeam Backup, Replication and Cloud Connect with iland Secure Cloud.

• VMware vSphere to Microsoft Hyper-V 2012 R2 migration. o Achieved $300,000 per year reduction in licensing costs by migrating from VMware to Hyper-V. o Converted all physical servers to virtual machines. Storage consolidation with Dell EqualLogic SAN.

• Office 365 migration: Migrated 750 active mailboxes from on premise Exchange 2010 to the cloud with zero downtime or business interruption. Migrated SharePoint 2010 to SharePoint Online. Migrated from on premise to Lync/Skype for Business.

• Veeam ONE installation for monitoring, reporting and capacity planning for our virtual environments.

• Microsoft SQL Server 2012 Enterprise upgrade and server consolidation. Consolidated seven SQL servers into two.

• Consolidated two ERP accounting systems into one centralized system (MRI into Yardi).

• Negotiated 50% reduction in Microsoft licensing. Saving $350,000 per year.

• Citrix 6.5 Presentation farm upgrade to XenApp/XenDesktop Enterprise Edition

• Managed Sarbanes-Oxley (SOX) compliance and annual audits with a 7-year track record of zero exceptions. o Developed and maintained IT controls, operating procedures, policies and system documentation.

• Avaya VOIP Unified Messaging migration from PBX phone system.

• Managed all online services.

o Website creation and maintenance for corporate entities and managed properties. Managed SEO, social media and online reputation for corporate entities and managed properties. Mark D. Johns, MBA, CISSP

17 Walker St. Boston, MA 02129

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Ipsen Biopharmaceuticals Milford, MA

Head of IT - US / IT Site Manager 2000 – 2010

Directed all IT functions for US-based operations. Reporting to the CIO in Paris, leading international teams responsible for infrastructure, networking, enterprise applications, disaster recovery, manufacturing and R&D software platforms.

• Directed the IT integration of two company acquisitions: Vernalis and Tercica. o 250 employees across two countries (USA, UK). Email consolidation, file server consolidation.

• Grew the company from Research, development, clinical, manufacturing and commercialization. private to going public (IPO)

• New data center design and construction. Lead the conversion from physical to virtual computing and SAN storage technologies. o Enabling agile software development for research and development.

• Lotus Notes to Google Apps migration project.

• Managed multiple ERP system migrations: Sage to Microsoft Great Plains Dynamics. Microsoft Great Plains Dynamics to SAP.

• International project manager for R&D, clinical and regulatory software applications. o Electronic Document Management System (EDMS). Electronic CTD submissions to the FDA. Electronic Lab Notebook.

• International project manager for Cisco VOIP deployment.

• Vendor management for enterprise applications, infrastructure, data and voice. SLA contractual agreements and negotiations.

• Maintained FDA compliance in a GxP biologic manufacturing operation.

• IT Security, deployment of 2-factor passwords based on RSA SecurID.

• Firewall security design and maintenance.

EDUCATION

Master of Business Administration, MBA Nichols College Bachelor Science, Management Information Systems University of Connecticut CONTINUING EDUCATION

Masters Certificate IS/IT Project Management Villanova University Graduate Certificate Linux Administration Worcester Polytechnic Institute CERTIFICATIONS

Certified Information Systems Security Professional, CISSP Microsoft Certified System Engineer, MCSE

Cisco Certified Network Associate, CCNA

SKILLS

Leadership and Management Skills: Advising, Coaching, Conflict resolution, Decision making, Delegating, Diplomacy, Interviewing, Motivation, People management, Problem solving, Strategic thinking.

Data analytics and data science: Data analytics, Data modeling. BI tools and applications, Data warehousing projects, analysis with Tableau and Power BI. Organizational Skills: Categorizing data, Coordinating, Goal setting, Meeting deadlines, Project management, Strategic Planning, Time management, Managing Remote Working Teams, Continuously Reviewing Processes for Improvement. Communication: Team Building, Leadership, Collaboration, Written Communication, Active Listening, Producing Complex Information in Digestible Amounts. IT Project Management & Governance: PMP, ITIL, COBIT, Lean Six Sigma, Kanban, Kaizen, PDCA cycle, Key Performance Indicators (KPIs), Dashboards Project Management: Scrum and Agile proficiency, Technical reporting, Work scheduling software, Data analytics Cybersecurity: Unified threat management, Gateway anti-virus, Application layer firewall and control, Deep packet inspection, Data loss prevention (DLP), Security information and event management (SIEM), 2-factor authentication, NIDS/HIDS, Tripwire, Nessus, WPA2 802.1x & AD/LDAP security, Antivirus. Cloud computing: Office 365, Microsoft Azure, Amazon Web Services AWS, Google GSuite Apps Cloud, SaaS software. Networking and wireless: Cisco, Merkai, Ruckus, Virtual private network (VPN), switches, routers, firewalls, SonicWALL, Fortinet, Cisco Pix, QoS. IT service management (ITIL): Jira Service Desk, Halp, Track-IT Virtualization: VMware ESXi, Hyper-V Infrastructure: HP, IBM, and Dell Servers, EMC, EqualLogic SAN, NetApp, Apple Macintosh, Lenovo Enterprise Applications and ERP: Netsuite, SAP, Microsoft Great Plains Dynamics, SAP Software: Windows Server, Linux, UNIX, System Center, Active Directory, Microsoft Exchange, Microsoft SQL Server, Microsoft SSRS, Business Objects, Mimecast, Veeva, Labguru, Mastercontrol, DocuSign, FlowJo, Procurify, Paylocity, Bamboo, ADP, Apache, IIS, SQL server, Oracle, Yardi, MRI, Entrata. Business Continuity / Disaster Recovery: Datto, Veeam, Unitrends, Symantec NetBackup Datacenter, Tivoli Storage Manager, Backup Exec, Azure Site Recovery, iLand Cloud replication, tape libraries. Compliance: Sarbanes-Oxley SOX, FDA, 21 CFR Part 11, Annex 11, HIPAA, GDPR, CCPA

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