Nipa Patel

Hillsboro, OR ***** 804-***-**** ad3bml@r.postjobfree.com

Education

Ph.D., Pharmacology & Toxicology May 2021 Aug 2016-May 2021 Virginia Commonwealth University

B.S., Chemistry and Biology Aug 2009-May 2014

Virginia Commonwealth University

Experience

Senior Scientist, Biomarker Services Jul 2021-Jul 2022 Pharmaceutical Product Development (PPD) Laboratory Services, Part of Thermo Fisher Scientific

• Independently developed high-throughput bioanalytical assays, leveraging existing immunoassays and new instrumentation platforms, for clinical patient sample analysis.

• Effectively communicated project updates and addressed stakeholder concerns, ensuring smooth project progression.

• Executed method validations, transfers, and bioanalytical testing of clinical samples, ensuring accurate and reliable results.

• Drafted, reviewed, and finalized bioanalytical methods and validation reports, adhering to industry standards.

• Troubleshot technical and mechanical issues during method development and validation, minimizing delays.

• Effectively managed time, project budgets, and workload for multiple projects, achieving timely completion of projects and documents.

• Coordinated internal and external resources to successfully meet project deliverables efficiently.

• Reviewed and approved technical data as per quality and compliance SOPs, methods, and client criteria and in accordance with Good Manufacturing Practices and Good Laboratory Practices.

• Maintained laboratory equipment and inventory, and trained new staff members. Virginia Commonwealth University, Doctoral Researcher Mar 2017-Jul 2021 Department of Pharmacology & Toxicology, Laboratory of Dr. David Gewirtz

• Employed flow cytometry, western blot analysis, and immunofluorescence to examine the cellular mechanisms induced by chemotherapy and radiation, focusing on autophagy and senescence.

• Elucidated the effects of autophagy inhibition on tumor cell sensitivity to chemotherapy and radiation by utilizing pharmacological autophagy inhibitors and lentiviral shRNA knockdown.

• Screened and identified potential therapeutics for mitigating chemotherapy-induced peripheral neuropathy.

• Managed and trained technicians and research students in lab techniques, cell-based assays, and data analysis Skills/Abilities

Computer Programs

• Proficient in Microsoft Office (Microsoft Word, Microsoft Excel, and Microsoft PowerPoint), LIMS, ELN, Veeva Vault, Trackwise, ImageJ, SigmaPlot, SoftMax Pro GxP Software and GraphPad Prism Technical Lab Skills

• ELISA, Protein Purification using Affinity Columns, SDS-PAGE Gel Electrophoresis, GMT, Bacterial Transformation and Culturing, Bacterial Colony Isolation, Tissue Cell Culture, Aseptic Techniques and Equipment Sterilization, Western Blot analysis, Lentiviral shRNA knockdown, Frozen tissue processing and sectioning, Immunofluorescence, immunohistochemistry, Data Analysis Instrumentation

• Biosafety Cabinet, UV-Vis Spectroscopy, Fluorescent Microscopy, RNA isolation, Quantitative Polymerase Chain Reaction (qPCR), Cyrostat, Flow Cytometry, Quanterix SiMoA HD-1 Analyzer, Meso Scale Discovery Immunoassays, and SpectraMax

Certification

Google Project Management Certificate, Coursera, 2023

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