PROFESSIONAL SUMMARY

PROFESSIONAL EXPERIENCE

EDUCATION

SKILLS

PROFESSIONAL AFFILIATIONS

**** ******* ***, ********, ***** Louis, MO 63114

ad39wf@r.postjobfree.com

RUPESH CHANDRA PANTA +1-618-***-****

Research Scientist- pharmacology

Diligent, collaborative, and versatile individual with over five years of experience working in the pharmaceutical industry and academic research institution. Skilled in pharmaceutical analysis, chemical characterization, animal handling, in vitro-cell based, pharmacology, ex vivo, and in vivo techniques. A quick learner motivated to make a meaningful impact by engaging closely with diverse scientific disciplines. Passionate about advancing novel science and dedicated to enhancing lives. Washington University in Saint louis (WashU), MO 2023 - Present Performed Gel electrophoresis, Plasmid isolation.

Executed PCR, Western blotting, Nanodrop, Transfection, Transformation techniques; streamlined experimental processes, resulting in 30% faster data generation and improved accuracy in a biotechnology laboratory environment.

Performed Genotyping and xenografting to study oncological pathways. Successfully executed Mice handling and drug administration through nasal routes.

Proficient in cell culturing, cell counting, media and sample preparation. Instrumentation: pH meter, autoclave, UV Vis spectroscopy. Executed FACS sorting and multi colored flow cytometry processes for cell analysis, leading to 25% more precise experimental outcomes. Southern Illinois University Edwardsville, IL 2021 - 2023 Evaluated the efficacy and safety of dapagliflozin as an adjunct to insulin in type 1 diabetic rats.

Conducted dosing of an animals daily via subcutaneous and oral routes. Checked blood glucose and body weights of animals daily. Assayed β-hydroxybutyrate, total cholesterol, High density lipoprotein, and triglyceride in 96-well plate.

Successfully implemented cell based biochemical techniques and ion channel research.

Performed data analysis using GraphPad Prism 6 software Presented research at graduate seminar and conferences. Aadee Remedies Pvt. ltd 2017

Production: Support GMP, Fast paced tablet section, high growth manufacturing process, stability testing, Semi-solid section, and Dry powder section.

Quality control : Operate and perform the calibration, validation, cleaning.

Quality assurance : Documentation review, revision, remediation, and process change controls

Research and Development

Masters in Pharmaceutical Sciences

Main courses: principle of drug action and development, Genetics and immunology, cancer biology and cell signaling. 2021 – 2023

Bachelors in Pharmacy

2014 – 2017

Molecular biology: PCR, Western blotting, multiparameter flow cytometry, immunohistochemistry, plate-based and T cell assay .

In-vivo: animal handling and husbandry, tissue and blood collection, tissue sectioning, small animal surgery, compound administration (SC, IP, Nasal, IM, and oral dosing). In-vitro: cell culture, immunoblotting, immunologic assays Analytical: UV-Vis, FT-IR, NMR, HPLC, GC, pH meter, Liquid chromatography) LC-MS, LC-UV, qPCR, FACS sorting,

ELISA, Mass spectrometry, Analytical Methods Development and Chromatography.

Analysis and graphing software: SPSS, MS-office, Excel, Email, PowerPoint, GraphPad Prism, ImageJ, JMP, Empower, Openlab.

GLP, GMP, LIMS, IACUC regulations

Microbiology: cell culture, agar diffusion test, multi-specific antibodies, cytokine-fusions, Human T cells.

Confocal microscopy (image processing and analysis), florescence microscopy, In vivo imaging.

Excellent verbal, written communication, leadership, critical thinking.

Time management and organization skills

Strong team player, attention to detail, highly motivated and flexible.

Graduate member American Society of Pharmacology and Experimental Therapeutics 2023 - Present

Graduate and Research Assistant at SIUE

Southern Illinois University Edwardsville, Graduate School Research Grant ($500)

Research Associate II

Research Assistant

In-plant training at Aadee Remedies Pvt. ltd Intern Southern Illinois University, Edwardsville

Manmohan Memorial Institute of Health Science

https://www.linkedin.com/in/pantarupesh07/

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