Research Associate Senior

CALE HEINIGER 269-***-****

****.********@*****.***

Austin, Texas

WORK EXPERIENCE ASURAGEN SENIOR RESEARCH ASSOCIATE

Austin, Texas February 2022 - November 2022

Provided expertise in developing strategies for integrating automation into workflows in research and development

Designed verification and validation experiments including guard-banding tests to measure IVD assays’ performance and move the product through the development stage Conducted statistical analyses using specialized software, such as JMP, to derive meaningful insights and inform project direction

Performed wet-lab experiments, including PCR and NGS, to support bioanalytics and molecular diagnostic development processes

DECIPHERA PHARMACEUTICALS, LLC SCIENTIST II

Lawrence, Kansas June 2018 - February 2022; November 2022 - Present Implemented automation solutions to meet the evolving needs of the laboratory including the addition of acoustic dispensers, robotics, and other automated liquid handling devices Validated liquid handling methods for diverse sample types on new and existing equipment to increase laboratory throughput and efficiency

Collaborated with other departments to implement new automation solutions to meet the evolving needs of the laboratory including the addition of acoustic dispensers, robotics, and other automated liquid handling devices

Designed and verified over 100 novel biochemical assays utilizing recombinant enzymes essential for the comprehensive characterization of small molecule kinase inhibitors throughout all stages of the drug development process Led early stage drug screening efforts and managed compound characterization potency database including processing, uploading, and analyzing large datasets PITTSBURG STATE UNIVERSITY 2016

Bachelor of Science in Chemistry and Biology Minor in Physical Science PUBLICATIONS & CLINICAL CANDIDATES Publication: "Preclinical studies with DCC-3116, an ULK kinase inhibitor designed to inhibit autophagy as a potential strategy to address mutant RAS cancers," Molecular Cancer Therapeutics, 2019. Clinical Candidates: DCC-3116, Phase 1 DCC-3084, IND filed DCC-3009, IND filed EDUCATION SKILLS & EQUIPMENT Advanced automation experience with the following instruments: Agilent Bravo, Tecan, Beckman Coulter Echo, Thermo Fisher Combi

Advanced expertise in coding and scripting languages, including Python and SQL Effective manager of projects and priorities accustomed to working in fast-paced environments

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