Versatile, collaborative, and accomplished Scientist with a Ph.D. in Chemical Engineering focusing on biopolymer synthesis and characterization, biomaterial synthesis, biopolymer and experience working in an R&D environment with highly sophisticated products featuring targeted drug delivery, pre-clinical cancer research. Recognized for leading an unwavering attention to detail and an absolute precision for development, troubleshooting and enhancement of products. Able to collaborate effectively with multiple disciplinary team of scientists and engineers, while upholding a commitment to safety, efficiency and overall excellence. Ready and willing to travel/relocate for the ideal opportunity.

AREAS OF STRENGTH

Hydrogels

Nanocompsites

Regenerative medicine

Biopolymer production

Biomaterial synthesis

Project Management

Oral and written communication

Research and Development

Analytical techniques including: GC,GC-MS FTIR, liquid Chromatography, UV-Visible, DLS, particle size measurements, XRD, BET, TGA, DSC, SEM, TEM, AFM, Fluorescence spectroscopy

PROFESSIONAL EXPERIENCE

Research scientist (Azad University, Amol Branch, Amol, Mazandaran) 2004- 2023

• Design of bio-scaffold conjugated with chitosan-PEG nano-carriers containing bio-macromolecules.

• Characterized and analyzed the bioconjugated and encapsulated compounds by different analytical techniques such as FTIR, UV-Visible, HPLC, LC-MS, DLS, particle size measurements, XRD, BET, TGA, DSC, SEM, TEM, AFM, Fluorescence spectroscopy.

• Developed biocompatible hydro-gels, and polymeric nanoparticles for in vitro and in vivo drug delivery systems for small/big molecules and studied their release profile, stability.

• Optimized analytical methods for characterization, QC tests of the developed therapy formulation, and quantification of drug release.

• Developed selective nanoparticle delivery strategy to transport particular drugs.

• Synthesised noisome and liposome vesicular nanocarriers loaded drug for Alzheimer and diabetic disease.

• Formulated and characterized long-acting injectable liposomes drug formulation.

• Characterized and performed kinetic study of injectable albumin-bound nanoparticle suspension formulation.

• Synthesized a thermogel modified with biomaterials as carrier for HUSSCs differentiation into cardiac cells.

• Designed a Novel 3D-Scaffold as a Potential Material to Induct Epidermal-Dermal Keratinocytes of Human-Adipose-Derived Stem Cells and Promote Fibroblast cells Proliferation for Skin Regeneration.

• Developed,Electrochemical sensing of Nalbuphine in pharmaceutical samples using amplified MgO/CNTs nanocomposite electrode.

Head of R&D group (Aras Bazar Pharmaceutical Company) 2013-2015

• Evaluating the novel strategies to produce value-added bio-products from biomass resources with application in pharmaceutical industries

• Quantitative/qualitative analysis using analytical instruments, including HPLC, GC (-FID, -MS), TEM, SEM, BET, XRD, NMR, Raman, and FTIR.

• Bioreactor Design and development.

Quality control & Production Manager ( Oojy Food Industry) 2003- 2004

• Managed the Inspection Functions, consisting of In-process and Final Inspection, Incoming material inspection, packaging and labeling of product.

• Monitored production and QC scrap, non-conforming material, rework, shipping, and training of personnel. Performed all personnel related functions related to QC

group including hiring, training, and performance evaluations.

• Responsible on controlling all QC equipment to ensure all units are within calibration and maintenance schedules. Coordinated and supported current and new

equipment qualification.

• Utilized data to identify opportunities to improve productivity with regards to inspection through-put and/or sampling plans.

• Coordinated with Logistics group for daily shipments to meet all customer demands.

• Developed, revised, implemented and maintained related procedures for QC and Production. Trained appropriate employees to the procedures

` Quality control manager ( Nankadeh Tabarestan) 2002-2003

QC and QA supervisor for food products and strong knowledge GMP, GLP, experience working in laboratory environment, participation in external and internal audits, experience working supervise labeling process, line inspections, finish products.Maintaining the quality programs like sanitation, environmental monitoring, hold tags and disposition, HACCP, product recall, pest control services, calibration and internal audits.

• Analyzing the customer complaints and circulating the reports for the Corrective Action Preventative Action (CAPA) along with maintaining the databases for CAPA and Supplier CAR.

EDUCATION

PhD in chemical Engineering- Biotechnology PhD thesis: Biopolymer production

Noshirvani University of Technology, Babol 2010

M.Sc. in Chemical Engineering- Biotechnology

Research and development, Tehran 2001

B.Sc. in Chemical Engineering- Food Industry

Mohaghegh Ardabili, Ardabil 1999

PUBLICATIONS

Design of bio-scaffold conjugated with chitosan-PEG nano-carriers containing bio-macromolecules of Verbascum sinuatum L. to differentiate human adipose-derived stem cells into dermal keratinocytes. International Journal of Biological Macromolecules. (2023)

Evaluation and comparison of anti-Alzheimeric effect of niosome and liposome vesicular nanocarriers loaded with curcumin galantamin in animal model. Material today bio, submitted.(2023)

Electrochemical sensing of Nalbuphine in pharmaceutical samples using amplified MgO/CNTs nanocomposite electrode. Journal of Composites and Compounds (2022)

Synthesis of thermogel modified with biomaterials as carrier for HUSSCs differentiation into cardiac cells: Physicomechanical and biological assessment. Materials Science & Engineering C, (2021).

Catalytic effect of solvothermally prepared Cu2 (bdc) 2 (bpy) metal-organic framework on thermal decomposition of ammonium perchlorate. Journal of Solid State Chemistry(2021)

Conjugation of Pectin biopolymer with Au-nanoparticle as a drug delivery system: Experimental and DFT Studies. Appl Organometal Chem. 2020

Design of Novel 3D-Scaffold as a Potential Material to Induct Epidermal-Dermal Keratinocytes of Human-Adipose-Derived Stem Cells and Promote Fibroblast cells Proliferation for Skin Regeneration .Fibers and Polymers, (2020)

Gelatin–Gold Nanoparticles as an Ideal Candidate for Curcumin Drug Delivery: Experimental and DFT Studies. Journal of Inorganic and Organometallic Polymers and Materials,(2020).

Media Optimization for Poly(β-hydroxybutyrate) Production Using Azotobacter Beijerinckii. International Journal of Polymeric Materials and Polymeric Biomaterials(2014).

The effect of carbon source supplementation on the production of poly (3 hydroxybutyrate co 3 hydroxyvalerate) by Cupriavidus necator.

Production of poly 3 hydroxybutyrate by Cupriavidus necator from corn syrup: statistical modeling and optimization of biomass yield and volumetric productivity.Journal of Chemical Technology & Biotechnology.(2010)

Growth kinetic parameters and biosynthesis of polyhydroxybutyrate in Cupriavidus necator DSMZ 545 on selected substrates. Chemical Industry and Chemical Engineering Quarterly/CICEQ (2011).

Optimization PHA production by Cupriavidus necator from molasses and acetate as substrate. (New Biotechnology), 2010

Optimization PHA production from cheese whey by Azohydromonas lata . (New Biotechnology), 2010

More of my publications are listed in my Google scholar profile.

References

Ruby Gulati Head Quality Engineering and Quality Management +1-408-***-****

Jahan Jowharchi Chief Technical Operations, Rion Health +1-510-***-****

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