Kimberly Kaye Bynote’
**** ***** ***** ***** *. Omaha, Ne 68112
*******@*******.***
PROFESSIONAL SUMMARY
Experienced, knowledgeable and detail-oriented chemist with an extensive background in forensic science, soil chemistry, medical laboratory science and molecular genetic research. QUALIFICATIONS
PCR, Q-RT-PCR DNA, RNA Isolation Cloning
Western Blotting Mapping ELISA
Cell and tissue Culture Flow Cytometry DNA Sequencing Laboratory Management Equipment Maintenance Budget/Financial Coordinator Personnel Training Excel Power Point
Word
EDUCATION
Bachelor of Science, Chemistry (Biology, Minor)
Black Hills State University, Spearfish, South Dakota, 1998 EMPLOYMENT AND PROFESSIONAL EXPERIENCE
2016 Chemical Analyst
Glaxo-Smith-Klein, Lincoln, NE
Duties: Quality control and finished product analysis in pharmaceuticals. 2003-2016 Research Technologist
University of Nebraska Medical Center, Omaha, NE
Duties: Gene expression analysis for colorectal cancer using Min mouse model. Estrogen regulation of Lupus using NZB/NZW mouse model. 2008-2009 Clinical Testing Analyst
Lasting Hope Recovery, Omaha, NE
Duties: Routine laboratory procedures in Hematology, Chemistry, Urinalysis, and Phlebotomy at a 64-bed in-patient psychiatric hospital.
2001-2003 Research Technologist
University of Nebraska Medical Center, Omaha, NE
Duties: Molecular biology techniques using reporter gene technology to determine biological functions in mouse genes.
2000-2001 Laboratory Support System
NHS Clarkson Hospital, Omaha, NE
Duties: Receive and process laboratory specimens. Phlebotomy. 1999-2000 Laboratory Coordinator/Graduate
University of South Dakota, Vermillion, SD
Duties: Coordinate undergraduate laboratories, set up and assist students with experiments. 1994-1998 Research Assistant: Department of Chemistry Black Hills State University, Spearfish, SD
Duties: Thermodynamics of RNA structure.
1989-1992 Laboratory Technician
Golden Reward Mining Co., Lead, SD
Duties: Quantitative and qualitative analysis of ores for gold, silver, copper, and zinc. 1986-1988 Laboratory Technician: Hematology/Phlebotomy Hawthorn Services, Inc., Madigan Army Hospital, Tacoma, WA Duties: Hematology, Coagulation, Urinalysis and Phlebotomy 2
1984-1985 Laboratory Technician
United Pathology, P.C., Sierra Vista, AZ
Duties: Autopsies, histotechnology, cytology, and administrative tasks. 1979-1984 Medical Laboratory Specialist
US Army USA MEDDAC, Ft. Huachuca, AZ
Duties: Autopsies, histotechnology, cytology, serology, blood banking, microbiology, phlebotomy, chemistry, urinalysis, and hematology. HONORS AND MEMBERSHIPS
Silver U Award Recipient, 2011
American Chemical Society. 1997-2001
Partner in Education, South Dakota Public School System, 1996 Honor Graduate, Primary Leadership Course, Ft. Carson, Colorado, 1981 PUBLICATIONS
Yoachim SD, Nuxoll JS, Bynoté KK, Gould KA. Estrogen receptor alpha signaling promotes Sle1-induced loss of tolerance and immune cell activation and is responsible for sex bias in B6.Sle1 congenic mice. Clin Immunol. 2015 Jun;158(2):153-66. doi: 10.1016/j.clim.2015.03.026. Epub 2015 Apr 7. Yuan F, Tabor DE, Nelson RK, Yuan H, Zhang Y, Nuxoll J, Bynoté KK, Lele SM, Wang D, Gould KA. A dexamethasone prodrug reduces the renal macrophage response and provides enhanced resolution of established murine lupus nephritis. PLoS One. 2013 Nov 28;8(11):e81483. doi: 10.1371/journal.pone.0081483. eCollection 2013.
Mikuls TR, Levan T, Gould KA, Yu F, Thiele GM, Bynote KK, Conn D, Jonas BL, Callahan LF, Smith E, Brasington R, Moreland LW, Reynolds R, Gaffo A, Bridges SL Jr. Impact of interactions of cigarette smoking with NAT2 polymorphisms on rheumatoid arthritis risk in African Americans. Arthritis Rheum. 2012 Mar;64(3):655-64. doi: 10.1002/art.33408.
Mikuls TR, Gould KA, Bynote KK, Yu F, Levan TD, Thiele GM, Michaud KD, O'Dell JR, Reimold AM, Hooker R, Caplan L, Johnson DS, Kerr G, Richards JS, Cannon GW, Criswell LA, Noble JA, Bridges SL Jr, Hughes L, Gregersen PK. Anticitrullinated protein antibody (ACPA) in rheumatoid arthritis: influence of an interaction between HLA-DRB1 shared epitope and a deletion polymorphism in glutathione S-transferase in a cross-sectional study. Arthritis Res Ther. 2010 Nov 18;12(6):R213.
Oikarinen SI, Cleveland AG, Cork KM, Bynote KK, Rafter JJ, Gustafsson JA, et al. Genetic mapping of Mom5, a novel modifier of Apc(Min)-induced intestinal tumorigenesis. Carcinogenesis 2009; 30:1591-6 Cleveland AG, Oikarinen SI, Bynote KK, Marttinen M, Rafter JJ, Gustafsson JA, et al. Disruption of estrogen receptor signaling enhances intestinal neoplasia in Apc(Min/+) mice. Carcinogenesis 2009; 30:1581-90 Bynoté KK, Hackenberg JM, Korach KS, Lubahn DB, Lane PH, Gould KA. Estrogen receptor-alpha deficiency attenuates autoimmune disease in (NZB x NZW)F1 mice. Genes Immun. 2008 Mar;9(2):137-52. Epub 2008 Jan 17.
Gould, K.A., Hansen, K.K., Strecker, T.E., Bynote, K.K., Pererson, K.A., and Shull, J.D. Genetic mapping of loci controlling diethylstilbestrol-induced thymic atrophy in the Brown Norway rat. Mammalian Genome 17(5):451-64, 2006.
Karen A. Gould,* Martin Tochacek,* Beverly S. Schaffer,* Tanya M. Reindl,* Clare R. Murrin,* Cynthia M. Lachel,* Eric A. VanderWoude,* Karen L. Pennington,* Lisa A. Flood,* Kimberly K. Bynote, Jane L. Meza,§ Michael A. Newton,** and James D. Shull 1 Genetic Determination of Susceptibility to Estrogen-Induced Mammary Cancer in the ACI Rat Mapping of Emca1 and Emca2 to Chromosomes 5 and 18. Genetics. 2004 December; 168(4): 2113– 2125.
deLannoy, P., Easterwood, L.M., Bynote, K., and S. Smith (1996). Structure leads to function: An integrated biophysical approach to teaching a biochemistry laboratory. Bioscene: Journal of College Biology Teaching 22, 3- 9.
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REFERENCES
Karen A. Gould, PhD
Associate Professor, GCBA
Vice Chair for Graduate Education, UNMC
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Scott Koepsell, MD, PhD
Assistant Professor of Pathology, UNMC
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Judy Kenyon
Research Technologist II, UNMC
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Karen Pennington
Research Technologist II, UNMC
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