Scott Rega

**** ********** ****, *********, ** **017

610-***-**** acvps8@r.postjobfree.com www.linkedin.com/in/scottrega

Education

M.S. Applied Mathematics

Indiana University of Pennsylvania

May 2014

Indiana, PA

GPA: 3.57

B.S. Ed. Secondary Mathematics

Kutztown University of Pennsylvania

Dec 2011

Kutztown, PA

Experience

Merck & Co., Inc.

Scientist, Quantitative Sciences – PPDM

Nov 2014 – Dec 2015

Rahway, NJ

Quantitative Pharmacology & Pharmacometrics, Merck Research Laboratories.

Apply pharmacokinetic/pharmacodynamics (PK/PD) and modeling and simulation approaches to characterize the kinetics of drug absorption and disposition (ADME), assess the dynamics of drug effect, and inform dose selection and go/no-go decisions.

Critical data management, analytic support for noncompartmental analyses (NCA), PK/PD and M&S activities, Quality Control, and Viral Dynamics Modeling.

Contribute to design, analysis, interpretation, and reporting of preclinical and clinical studies.

Authored numerous Clinical Study Reports, PK Memos, and Statistical Analysis Plans.

Contributed to multiple compounds that went for filing with the FDA and EU.

Quantitative Systems Pharmacology (QSP) Diabetes mellitus type II modeling in Matlab to create virtual patients to simulate clinical trials with the use High Performance Computing.

High Performance Computing Clusters – Charlotte Technology Center High Performance Computer (CTCHPC) Cluster is a Linux cluster used for modeling and simulation with Matlab.

Code Library Development Team member and assisted with the creation of the ‘QP2misc’ package in ‘R’ using SvN Version Control to assist with graphing and data manipulation, implemented Immutable Table Process, and to improve visualization and modeling and simulation workflow.

Software included use of ‘R’, R-Studio, Matlab, Excel, SigmaPlot, Phoenix, Watson, PKS, RCAM, MIDAS, and NONMEM through PsN DOS Commands.

IUP Mathematics Department

Graduate Assistant

Aug 2012 – May 2014

Indiana, PA

Research assistant in mathematical statistics with use of the software program ‘R’ focusing on distributions.

Developed information matrices and calculated moment generating functions and expected values.

Dealt with properties of the Weighted Generalized Lindley Distribution, which is used for life distribution modeling and is useful for data with all types of hazard rate functions.

Tutored undergraduate students in all areas of mathematics at the IUP branch campuses located in Punxsutawney, Northpointe, and IUP main campus.

Lancaster General Health

Information Services Graduate Intern – Business Intelligence

May 2013 – Aug 2013

Lancaster, PA

Predictive Modeling for the Business Intelligence Team and Information Services

Department.

Built models from scratch to determine likelihoods of given scenarios in the

healthcare field using logistic regression and statistical analysis.

Provided clinical and quality decision support through risk analysis, data mining,

and innovative model building and refining.

Intensive use of statistical-based software program ‘R’, Microsoft Excel, Minitab,

MS-DOS, SQL, and database systems such as Midas.

Sylvan Learning Center

Tutor

Nov 2011 – Jan 2013

Easton, PA

Tutor students after school hours and on weekends in accordance with standards.

Technical Skills

Mars Rover Optimal Path Determination, Independent Research Team NASA Project.

Analytical thinking skills and advanced insight toward applicable scenarios.

Quantitative and Data Analysis.

Applied Mathematics, Operations Research, and Statistics.

Text formatting and office computing: Microsoft Office Suite, MS-DOS, SQL, MySQL, Oracle, LaTeX, MiKTeX.

Mathematical Programs include extensive use of R-Statistics, Matlab, Mathematica, Sage, Arena, Lindo, Lingo, lpSolve, SPSS, Minitab, Microsoft Excel, GeoGebra, Geometer’s SketchPad, and SigmaPlot.

Differentiating and analyzing characteristics and behaviors of functions towards applications, probability, and statistics.

Predictive modeling and model building.

Collaborate with external vendors to enhance modeling and simulation capabilities.

Business of Sports Certificate involving management, marketing, law, and business aspects.

Honors

Merck Award for Excellence for outstanding performance on behalf of MRL Preclinical Development and HIV Integrase Discovery Team, July 2015

HCV Doublet recognition presented by Merck PPDM QP2, 2015

Scholarships - Creating Opportunities for Applying Mathematics

(National Science Foundation STEM)

Graduate Assistantship – Mathematics Department

Dean’s List

Business of Sports Certificate

Outstanding Community Service Hours

Presentations

Title / Year

Quantitative Systems Pharmacology Diabetes Modeling / 2015

Elimination and Clinching Optimization in Baseball & Mars Rover Optimal Path Determination, IUP Presentation Day / May 2014

Mars Rover Optimal Path Determination, Allegheny Mountain Section, MAA, Westminster College / Apr 2014

Airport Simulation and Optimization of Passenger Flow using Arena, Joint Mathematics Meeting, Baltimore, MD / Jan 2014

Mathematics Department Internship Presentation / Sep 2013

Resume Workshop, S-COAM / Sep 2013

White-tailed Deer Forecast, PASSHEMA Regional Conference, Clarion University of Pennsylvania / Apr 2013

Research Topics

Title / Year

Hyperinsulinemic-euglycemic clamp for Type II Diabetes / 2015

Mars Rover Optimal Path Determination, Independent Research Team NASA Project / 2014

Elimination and Clinching Optimization in Baseball / 2014

Solving Linear Programming Problems Using R: Four Approaches / 2014

Rayleigh-Ritz Methods for Eigenvalues / 2013

Finite Element Modeling: Convection Diffusion Equation / 2013

Airport Simulation using Arena / 2013

Image Interpolation / 2013

Finding Alzheimer’s Disease Earlier Through Better Analysis / 2013

Modeling Antlerless White-tailed Deer in Pennsylvania / 2012

An Analysis of Economic Fluctuations in a Mixed IS-LM Business Cycle Model / 2012

Cell Phone Company Analysis using Analytic Hierarchy Process / 2012

Game Theory / 2012

Loop Analysis of Circuits / 2012

Developing the Brain: “Secondary Education Mathematics and the Development of Student’s Brains” / 2010

Courses of Relevance

Applied Math:

Ordinary and Partial Differential Equations (641), Modeling and Simulation (547), Advanced Simulation (647), Topics in Applied Computational Mathematics (581), Analysis for Applied Mathematics (625), Numerical Mathematics (640)

Operations Research:

Probabilistic Models in Operations Research (546), Deterministic Models in Operations Research (545), Nonlinear Optimization Programming Models (645)

Statistics:

Applied Statistical Methods (667), Mathematical Statistics I (563), Mathematical Statistics II (564)

Merck Polytechnic Institute:

Intro Clinical Statistics at Merck Research Laboratories

PK/PD Modeling – University at Buffalo – SUNY

Nonlinear Mixed Effects Modeling – Uppsala University

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