Medical Devices Development, surface modification, mechanical testing

CHIH-WEI LIAO, PhD

Permanent Resident

North Wales, Pennsylvania 19454

352-***-**** *******.*****@*****.***

SENIOR R & D SCIENTIST TECHNICAL LEAD

Plastics Oil Chemicals Medical Devices

SUMMARY

Hands-on solutions-driven R&D scientist and technical lead with extensive experience conducting innovative research and processing within industries. Proven aptitude for analytical, chemical and biomedical problem-solving with consistent, successful delivery of results. Expertise in innovation of next generation of high performance polymers, differentiation of technologies for the need of product development through a stage gate process, concept validation from R&D stage into production, filing technical gap based on customer needs, analytical methodologies of materials, scaling up polymers / additives, and guiding formulation / compounding / extrusion / molding of polymers / additives in ISO 9001 manufacture environment. Team leader in cross-departmental collaboration.

10+ Years in Plastics Processing / Characterization Familiar with Relationship between Polymer Structure and Properties DOE Spectroscopy Microscopy Thermal Analysis (DSC/Rheology/TGA) Translating Technical Requirements into Business Objectives Specification of Raw materials via Statistical Analysis Experience in Medical Devices Development Complied with FDA 510K

PROFESSIONAL EXPERIENCE

Greene, Tweed & Co., Kulpsville, PA 2011-2015

Worldwide Leader of rubber / thermoplastics based seal components with approximately 1500 employee

R&D Scientist 2014-2015

Research Engineer 2011-2014

Innovated high performance thermoplastics / thermoset plastics (PEEK, PAEs, PI, PSU, etc.), meeting demanding requirements in wet / high temperature working environment with high strength and broad chemical resistance. Formulated additives in polymer matrix serving as seal components for oil / semiconductor / aerospace industries. Explored advantages of current R&D plastics to the potential competitive materials/products.

Increased future portfolio $4M by developing enhanced PAEKs seal components (Arlon 3000XT®) which raised working temperature from 200 C to 350 C and sustained performance in chemicals/steam environment.

Solved the current market gap in continuous operation under the hot wet / harsh environment by investigating high performance polymer thin films as insulated layers on metal wires in electronic components.

Sustained product long-term performance of product and reduced the level of residual volatiles by identifying trace residual volatiles / impurities in products via TGA-MS / ICP-MS.

Improved product performance and extended application temperature by evaluating and formulating xlinking capacity of xlinkers in polymer resins.

Facilitated product development by guiding the compounding / molding condition of the plastics via rheology / thermal analysis / twin screw extruders.

Enhanced cost-effective manufacture process by performing DOE and life time / kinetics modeling via TA Thermal Specialty Library.

Obtained consistent results by writing project progress reports and SOPs of testing methods and training engineers / technicians based on SOPs.

Expanded product line by working with external vendors developing and scaling up new polymer resins / curatives for product commercialization.

UNIVERSITY OF FLORIDA, Gainesville, FL 2007-2010

Graduate Assistant

CHIH-WEI LIAO Page 2 *******.*****@*****.***

Oversaw research on reversible electro-active biosensors and specific separation of mineral particles. Conducted research on methods for improving froth flotation techniques for separation of mining particles by innovating bio-surfactants to differentiate minerals with similar surface properties. Researched techniques for achieving reusability of micro / nano biosensors with multi-functionality. Identified and developed strategies for pursing grant funding.

Established feasibility of development of small, high-efficiency microelectronics designed to operate within biological systems by recognizing polypeptides screened by phage display techniques as binders on inorganic substrates.

Proved self-cleaning capability of nano-device surfaces through utilization of electro-activated polypeptide linkers.

Reduced dose of micro-organism surfactants to 0.96 mg per gram of mineral particles during flotation process, decreasing micro-organism surfactant dose by 10-100 times.

Conducted research that laid groundwork for new biotechnologies with exciting possibilities in commercial applications ranging from military to private healthcare sectors.

Secured $623K in grant money to pursue research in electroactivated peptides for dynamic functionalization and $60Kto research particle separation using inorganic binding peptides.

Filed USA patent 2010 for Electroactivated Peptides and Biosensors.

EXACTECH, INC., Gainesville, FL 2007-2009

Orthopedic device / biologics manufacturer with 550 employees

Biomaterials Researcher

Conducted extensive research enhancing performance of bone replacement and repair materials complied with 510K. Researched extending longevity of hip acetabular cup components by improving wear/fracture toughness/yield strength of Ultra High Molecular Weight Polyethylene (UHMWPE). Researched biological activity of partial and fully demineralized bone matrix (DBM) used as implants for bone defect repair. Researched enzymatic dissociation of extracellular matrix of cartilage for use in cartilage tissue regeneration.

Increased the fracture toughness and yield strength of UHMWPE by formulating and enhancing xlinking via heat treatment.

Increased competitive advantage by decreasing wear reduction in hip acetabular cup components using high heat treated UHMWPE 75% compared with conventional materials.

Presented results of heat treatment experiments and ASTM2214 error discovery in the measurement of UHMWPE crosslink density at 2008-2010 SFB and ORS annual meetings.

EDUCATION

PhD in Materials Science & Engineering, Polymers Division

University of Florida, Gainesville, Florida

BS / MS in Applied Chemistry, Polymer Chemistry Division

National Chiao Tung University, Hsin-Chu, Taiwan

LABORATORY TECHNIQUES & SKILLS

Rheology DMA DSC/MDSC GPC XRD FTIR NMR SEM / EDX ICP-AES UV-Visible HPLC TGA-MS GC-MS Instron Twin Screw Extruder Injection Molding Compression Molding

COMPUTER SOFTWARE

Minitab Thermal Specialty Library MS Office SciFinder Patent Search

PATENTS

USA patent 2010: Electroactivated Peptides and Biosensors

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