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Medical lLaboratory, Cytogeneticist, Molecular

Location:
United States
Posted:
April 15, 2016

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Resume:

Dr. ADITI DASTANE

M.B.B.S, M.D. (Pathology), FACMG (UCLA, USA), CLSp (CG)

Maiden name: Dr. Aditi Khurana

Address: Row house no. 34, Swaroop Park Society,

Near Gandhi Bhavan, Kothrud,

Pune, Maharashtra state, India 411038

Phone: +91-942*******

Email ID: acudkw@r.postjobfree.com

Current job: Consultant Molecular Pathologist &

Consultant Geneticist & Counsellor

April 2010 - present Incharge and Director,

Molecular Diagnostic Laboratory and

Cancer Genetics Clinic

Deenanath Mangeshkar Hospital and Research Centre,

Pune, India

Fellowships:

Aug 2007- Sept. 2009 Clinical Fellow

Clinical and Molecular Cytogenetics Lab.,

Dept. of Pathology & Laboratory Medicine,

David Geffen School of Medicine,

University of California Los Angeles (UCLA),

CA, USA

June 07- July 07 Visiting Physician, Dept. of Pathology,

Cedars-Sinai Medical Center, Los Angeles, CA, USA

April 07- May 07 Visiting Fellow, Rheumatology Laboratory

Dept. of Medicine, UCLA, CA, USA

June 06 - Dec 06 Senior registrar-II, Hematopathology Laboratory,

Tata Memorial Cancer Hospital, Mumbai, India

March 06 - May 06 Clinical assistant, Department of Laboratory Medicine,

P.D. Hinduja National Hospital & Medical Research Centre, Mumbai, India

Mar 05 - Feb 06 Senior registrar-I, Surgical Pathology Laboratory, Tata Memorial Cancer Hospital, Mumbai, India

Residency:

Jan 02- Jan 05 MD Pathology, B.J. Medical College and Sassoon General

Hospitals, Pune University, India

Mar 01- Oct-01 Medical Officer, Rural Training Centre, Shirur, India

Feb 00 - Feb 01 Internship in Sassoon General Hospitals, Pune, India

Medical School:

1995 to 1999 B.J. Medical College, Pune University, India

Professional Skills:

Molecular genetics: DNA & RNA extraction, cDNA synthesis, conventional PCR, real-time PCR, restriction digest, capillary and gel electrophoresis, gene sequencing, gene expression analysis, LIPA, Southern blot.

Array Comparative Genomic Hybridization: sample processing, data analysis

Fluorescence in situ hybridization: manual and automated analysis of fresh samples, paraffin embedded sections, touch preps and tissue microarrays

Cytogenetics: includes high resolution karyotyping, digital image capturing

Tissue culture (insitu and flask method): stem cells, bone marrow aspirate and biopsy, neoplastic blood, FNAC, solid tumor, skin, products of conception, chorionic villus- direct and long term, amniotic fluid, peripheral blood for constitutional studies

Special stains: G-banding, C-banding, NOR staining and other tissue stains

Flow Cytometry: processing and analysis

Immunohistochemistry: staining, manual and automated image analysis

Hematopathology: processing, analysis of blood and bone marrow specimens

Surgical pathology & Cytology: Grossing, processing and reporting of specimens,

biopsies, FNAC, PAP smears, special stains, frozen-section and autopsies

Publications:

Book chapter on “Clinical applications of molecular onology in breast cancer” in 2014

LaRochelle J, Dastane A, Shuch B et al. Chromosome 9p deletions in clear cell carcinoma detected by fluorescent in situ hybridization (FISH): a marker of tumor aggressiveness and predictor of shorter disease-specific survival. Cancer. 2010 Oct 15;116(20):4696-702.

Gupta R, Dastane AM, McKenna R Jr, Marchevsky AM. The predictive value of epidermal growth factor receptor tests in patients with pulmonary adenocarcinoma: review of current "best evidence" with meta-analysis. Hum Pathol. 2009 Mar;40(3):356-65

Gupta R, Dastane A, McKenna RJ Jr, Marchevsky AM. What can we learn from the errors in the frozen section diagnosis of pulmonary carcinoid tumors? An evidence-based approach. Hum Pathol. 2009 Jan;40(1):1-9

Dadmanesh F, Xuemo F, Dastane A, Amin M, Bose S. Comparative Analysis of size estimation by mapping and counting number of blocks with DCIS in breast excision specimens. Arch Pathol Lab Med. 2009 Jan;133(1):26-30

Gupta R, Dastane AM, Forozan F, Riley-Portuguez A, Chung F, Lopategui J,

Marchevsky AM. Evaluation of EGFR abnormalities in patients with pulmonary adenocarcinoma: the need to test neoplasms with more than one method.

Mod Pathol. 2009 Jan;22(1):128-33

Khurana AS, Rekhi B, Kane SV, Shukla P, Ramadwar M. Pancreatic tuberculosis masquerading as pancreatic carcinoma in two cases: role of fine needle aspiration cytology in diagnosis. Cytopathology 2007;18(6),380–383

Kane S, Khurana AS, Parulkar G, Shet T, Prabhash K, Nair R, Gujral S. Minimum diagnostic criteria for plasmablastic lymphoma of oral/sinonasal region encountered in a tertiary cancer hospital of a developing country. J Oral Pathol Med. 2009 Jan;38(1):138-44

Khandekar MM, Khurana AS, Deshmukh SD, Kakrani AL, Katdare AD, Inamdar AK. Platelet volume indices in patients with coronary artery disease and acute myocardial infarction: an Indian scenario. J Clin Pathol. 2006 Feb;59(2):146-9

Presentations:

Paper presentation on" Unravelling the Genetic Basis of Glaucoma in India with Genome Wide SNP Microarrays and DNA Pooling (SNP-Map)" in Annual Research society meeting of DMH, Pune 2011

Platform paper presentation on “Making sense of the Her-2/Neu (HER2) Immunohistochemistry (IHC) Equivocal Category Post-ASCO/CAP Guidelines” by Dastane A, Bose S at the USCAP 2009 conference, Boston, MA, USA

Platform paper presentation on “Problems with the Diagnosis of Carcinoid Tumor on Pulmonary Frozen Sections” by Dastane AM, Gupta R, McKenna RJ, Marchevsky AM at the USCAP 2008 conference, Denver, CO, USA

Poster on “Effect of ASCO/CAP Recommended Guideline for Positive Her2/neu Stain on FISH Concordance- An Evidence Based Study” by Dastane AM, Alsabeh R, Bose S at the USCAP 2008 conference, Denver, CO, USA

Poster on “Evidence Based Pathology: Are EGFR Tests Valid Predictors of Treatment Response to Erlotinib or Gefitinib in Patients with Pulmonary Adenocarcinoma?” by Dastane AM, Gupta R, McKenna RJ, Marchevsky AM. at the USCAP 2008 conference, Denver, CO, USA

Poster on “Lessons Learnt from Mistakes and Deferrals in Frozen Section Diagnosis of Pulmonary Lesions: An Evidence Based Pathology Approach” by Gupta R, Khurana AS, McKenna RJ, Marchevsky AM at USCAP 2008 in Denver, CO, USA

Poster on “EGFR Molecular and Phenotypic Evaluation in Patients with Pulmonary Adenocarcinoma: A Comparison of Different Methodologies and a Proposal for an Algorithmic Approach to EGFR Testing” by Marchevsky AM, Gupta R, Dastane AM, Forozan F, Riley C, Lopategui J. at the USCAP 2008 conference, Denver, CO, USA

Platform paper presentation on “Plasmablastic Lymphoma Of The Oral And Sinonasal Mucosa – Is It A Morphological Diagnosis?” by Khurana AS, Kane S, Maru D at the All India Pathologists Conference (APCON 2005) in Indore, India

Platform paper presentation on “Platelet volume indices in patients with coronary artery disease and acute myocardial infarction: an Indian scenario” by Khurana AS, Khandekar MM, Deshmukh SD at the All India Pathologists Conference (APCON 2004) in Pune, India

Platform paper presentation on “Cytohistopathological correlation of PAP smears- a critical appraisal” by Khurana A, Rane S, Deshmukh SD at the B.J. Medical Research Society Conference 2003 in Pune, India

Workshops/Conferences/Lectures conducted:

Panel faculty on genetics of breast cancer in Current trends in Oncology-Breast chapter held at Ruby Hall, 2016

Talk in CME on Genetics in Gynecological cancer at IMA Hall, Pune, 2015

Faculty lecture on Cytogenetics of bone tumors at MAPCON in Sept. 2015, Pune

Lecture on My most memorable mistake in Evidence based medicine conference held in Tata Memorial Hospital, Mumbai, 2015

Panel faculty on cancer genetic counseling in ICON, Hyderabad, 2015

Conducted preconference workshop on Laboratory Genetics in Pedigen conference held in Feb 2015 at DMH, Pune.

Talk on “HER2 FISH update on ASCO/CAP 2013 guidelines” organised by Sphere (Roche) in Ruby Hall Clinic in 2014.

Talk on Molecular Diagnostics at the monthly IAPP meet in Jan 2014

Organising secretary for CME and workshop on "Practical Utilities of Newer Diagnostic Modalities in OncoPathology" in Deenanath Mangeshkar Hospital, Pune on 20th October 2013.

Lecture on 'Cancer genetic testing- a current scenario' in Cancer Genetics, a symposium organised by Persistent Systems on 20th Sept. 2013

Faculty lecture on "Genetic testing in Aging" at the Indomedicon 2013 at Mumbai

Conducted workshop on Laboratory Genetics in Pedigen conference held in Feb 2012 at Pune

Faculty for certificate course in Medical and Reproductive Genetics at Maharashtra University of health Sciences (MUHS), Pune 2011 onwards till date

Lecture on 'Genetic correlation of beta-thalassemia intermedia' in Hematocon, 2012

Lecture on 'JAK2 mutation testing' in Pune hematology meet, 2011

Lecture on 'Molecular Genetics of Fanconi anemia' in Pune hematology meet, 2011

Teaching experience:

Co-guide for Diplomat of National Board (DNB) Pathology students in DMHRC

15 years of teaching experience for residents, medical students, nursing students, radiotherapy students, laboratory technologists and technicians

Awards:

Surgical Pathology award for the best poster at USCAP 2008 in Denver, CO on “Lessons Learnt from Mistakes and Deferrals in Frozen Section Diagnosis of Pulmonary Lesions: An Evidence Based Pathology Approach” by Gupta R, Khurana AS, McKenna RJ, Marchevsky AM

“The Best Investigator Award” for “Effect of ASCO/CAP Recommended Guideline for Positive Her2/neu Stain on FISH Concordance- An Evidence Based Study” by Medical Association of Los Angeles in 2008

“US President’s award” for Volunteer service at Cedars-Sinai Medical Center in 2008

Stood second in the University of Pune, India for the M.D. (Pathology) examination in 2004

Certifications & Memberships:

Article Reviewer for the SAJC: South Asian Journal of Cancer

ISHBT: Indian Society of Hematology & Transfusion Medicine: Life member since 2013

ISHG: Indian Society of Human Genetics: Life Member since 2013

ABMGG: American Board of Medical Genetics and Genomics: Clinical and Molecular Cytogenetics in 2009

ASCP: American Society of Clinical Pathology:Clinical Laboratory Specialist in Cytogenetics in 2009

MMC: Maharashtra Medical Council (MD Pathology & MBBS) since 1999

USCAP: Eligible for College of American and Canadian Pathology membership

References:

USCAP: Eligible for College of American and Canadian Pathology membership

References:

1. Dr Nagesh Rao, PhD, FACMG

Prof and head Cytogenetics lab

David Geffen school of medicine FACMG

acudkw@r.postjobfree.com

2. Dr Wayne Grody, MD, FACMG

Prof and head Molecular Genetics lab

David Geffen school of medicine,UCLA, USA

acudkw@r.postjobfree.com

3 Dr Sumeet Gujral

Prof of Pathology,

Tata Memorial hospital, Mumbai, India

acudkw@r.postjobfree.com

4. Dr. Chetan Deshmukh

Head of Oncology dept.

Deenanath Mangeshkar Hospital

Pune, India

acudkw@r.postjobfree.com



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