Medical Management
Resume:
Galina Strizheva, MD
*********@*****.***
Sammamish, WA
www.linkedin.com/in/galinastrizheva/
RESEARCH, SUPPORT AND MANAGEMENT PROFESSIONAL
Extensive experience in the fields of Immunology, Oncology, Molecular and Cell Biology, Pharmacology and Physiology in academic and clinical research environment, as well as Fortune 500 medical technology company and CRO settings. Impressive record in modern biotechnologies and research expertise. Innovative trainer and developer with comprehensive knowledge of biological research methods, current working knowledge of GLP, GCP and GMP. Highly accurate and effective communicator with excellent team-building and interpersonal skills; work well with colleagues and clients at all levels. Recognized as to go person and creative problem solver. Achieves complicated tasks in smarter ways by combining experience, creativity, collaborative spirit and passion for results.
EXPERTISE
Project Management
Assay Development
People Management
Leadership
Data Analysis
Customer Interactions
Troubleshooting
Training & Development
Problem Solving
Research Methodology
Creativity
Collaborations
EDUCATION
Medical Doctor with research emphasis (MD), Molecular and Cell Biology, 2000
Bachelor of Science (BS), Medical Biochemistry, 1997
Russian State Medical University, Moscow, Russia
Master of Science in Research (MS), Pharmacology and Physiology, 2006
Saint Louis University, School of Medicine, St. Louis, MO
DIAGNOSTIC AND RESEARCH METHODOLOGIES
Immunology: Luminex, ELISA, ELISPOT, Multicolor Flow Cytometry (extra- and intracellular staining), ADCC and variants, biologics safety (therapeutic antibodies, ADC), immune checkpoints, ex-vivo and in vitro cellular models
Cell Culture, Proliferation and Viability Assays: maintenance of primary and cancer cell culture; viability and proliferation assays (MTT, alamarBlue, H3-Tymidine incorporation, BrdU incorporation and staining, LDH); cell imaging
Protein Biology: immunohistochemistry, immunofluorescence, Western blot analysis, IP
Hematology and Cytogenetics: cultivation of the lymphocytes and amniotic fluid; harvesting and preparation of cytological slides; analysis of high-resolution chromosomes; in situ hybridization (FISH and CISH), colony forming cell assays (hematotoxicity)
DNA and RNA: Quantigene; DNA and RNA preparation; PCR and RT-PCR; SDS-page, gel-electrophoresis and blot hybridization; microsatellite analysis; SSCP and heteroduplex analysis; direct genomic sequencing
Cloning Techniques and Microbiological Methods: transformation; transfection; development of mammalian stable cell lines
Computers and Software
Extensive knowledge of PC, MS Office Suite, advanced MS Excel and MS Access, MS Project, SharePoint; computer e-learning systems; e-forms, database, statistical and data analysis (GraphPad, SpotFire, XlFit etc.), Electronic Document Management Systems (EDMS), LIMS, CRM; general biological search engines and bio-software, including scientific imaging software (ImageJ, Photoshop); basic programming; Flow Cytometry software (InCyte, FlowJo, Kaluza, CytExpert etc.).
Galina Strizheva, MD
*********@*****.***
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PROFESSIONAL EXPERIENCE
REACHBIO, LLC, Seattle, WA 2015 - present
Sr. Scientist, Immunology Division Manager
Boosted services revenue by 10% and introduced new clients to the company by establishment in vitro immunology line of pre-clinical CRO services covering immunogenicity, immunotoxicity, biomarker selection and profiling, off target binding and custom assay development. Development of exhausted T cells in vitro model for testing immune checkpoint modulators.
EUROFINS PANLABS (former RICERCA BIOSCIENCES), Redmond, WA 2011 - 2014
Sr. Scientist, Immunology Department Manager
Group and Project Management / Technical Director roles. Key accomplishments:
Created successful consultancy-based approach for contract research services by designing scientifically relevant projects applicable to customer's area of interest using in vitro Immunology assays and validated cellular models. Compiled quotes for studies, calculated cost of the project, and evaluated feasibility of custom requests.
Improved retention of existing clients by providing timely response for inquiries, fast turnaround of studies, high data quality and expertise in data interpretation.
Increased number of new clients by conducting cell biology and immunology training for the Business Developers, preparation of marketing materials and trade-show documents.
Facilitated productivity of Immunology Group by careful resources and workforce planning. Daily management activities included: supervision of scientific and technical personnel, studies schedule, negotiation of necessary consumables with manufacturers, staff training, SOPs, protocols writing, evaluation of new technologies, facilitation of group meetings and cross-functional collaborations.
Developed new models and assays, which increased immunology and bioanalytical portfolio.
Safety Committee Chairperson, Innovations committee member, QA backup, IRB liaison.
Scientist, Immunology Department
Study Director Responsibilities: effectively conducted customer studies using validated protocols, facilitated development of cell-based assays for pre-clinical screening of immunomodulatory compounds. Developed and implemented Cytokine Storm assay for pre-clinical screening of anti-inflammatory and potentially immunogenic compounds. Leadership role in the department.
THERMO FISHER SCIENTIFIC INC. (former LIFE TECHNOLOGIES), Camarillo, CA 2007 - 2010
Technical Applications Scientist II, Immunoassays, antibodies and CISH
Executed troubleshooting, problem solving and coaching skills in order to achieve customer’s professional success and support pre- and post-sales issues. Leadership role in the department.
High level of subject matter expertise in key company products in areas of Clinical Diagnostics, Protein Science and Immunology, resulting in increased customer satisfaction by 20%.
Departmental expert for company’s FDA approved medical devices.
Reduced number of common customer inquiries by design and delivery of educational resources for customers’ self e-learning portal (detailed SOP, protocols, assay tips and tricks).
Formalized and straightened inter-group communications resulting in quicker turn-around for resolving issues; served as point of contact and leader for group administrative needs.
Internal projects outside the scope of Technical Support scientist: marketing - usability of Invitrogen products and tools for customers (sales blitz, training sessions), customer interests reports; quality - FDA and ISO site visits meetings; IT - lead on soliciting website feedback and systems upgrades reviews.
AMGEN INC, Thousand Oaks, CA 2006 - 2007
Contract Associate, Investigative Toxicology group, CBSS
Supported pre-clinical studies by routine RNA extractions from animal tissues and cell cultures, accessed quality of RNA by Agilent Bioanalyzer and NanoDrop instruments, microarray analysis.
Galina Strizheva, MD
*********@*****.***
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CARDINAL GLENNON CHILDREN’S HOSPITAL, St. Louis, MO 2001 - 2002
Medical Lab Technologist, Cytogenetics and Molecular Genetics Clinical Laboratory
Mastered in clinical analysis of cytogenetic markers for patients with oncologic diseases. Provided critical input in clinical research experiments and data collection, directed analysis, and generated findings and implications.
FOX CHASE CANCER CENTER, Philadelphia, PA 1999 - 2000
Research Assistant, Clinical and Molecular Genetics Laboratory
Using different DNA methodologies, studied genotype-phenotype correlations and molecular biology of the Tuberous Sclerosis Complex.
RESEARCH CENTRE FOR MEDICAL GENETICS, Moscow, Russia 1997 - 1999
Research Assistant, Medical Genetics and Cytogenetics Laboratory, Children’s Hospital
Maintained and cultivated short term cell cultures of lymphocytes, prepared cytological slides, analyzed them in the search for cytogenetic markers, performed gene-candidate mutations detection using DNA methods for the study of blood cancers affecting children.
SELECT PUBLICATIONS
1.Development of an in vitro pre-clinical cellular assay to predict induction of Cytokine Storm by therapeutic antibodies
GALINA STRIZHEVA, APRIL RANDHAWA, JENNY MULLIGAN, CHRISTINE O’DAY
The Journal of Immunology, 2012, 188, 125.16
2.The Spectrum of Mutations in TSC1 and TSC2 in Women with Tuberous Sclerosis and Lymphangioleiomyomatosis
GALINA STRIZHEVA, THOMAS CARSILLO, WARREN D. KRUGER, EUGENE J. SULLIVAN, JAY H. RYU, ELIZABETH PETRI HENSKE
Am. J. Respir. Crit. Care Med. January 1, 2001 vol. 163 no. 1 253-258
3.A novel missense mutation in the GTPase activating protein homology region of TSC2 in two large families with tuberous sclerosis complex
LEENA KHARE, GALINA STRIZHEVA, JULIA N BAILEY, KIT-SING AU, HOPE NORTHRUP, MOYRA SMITH, SUSAN L SMALLEY, ELIZABETH PETRI HENSKE
J Med Genet, 2001;38:347–349
PROFESSIONAL AFFILIATIONS
THE AMERICAN ASSOCIATION OF IMMUNOLOGISTS, Active Regular Member
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