qPCR

CURRICULUM VITAE

R.Venkatesh Babu

Mobile No: +91-948*******

Email ID: ******.*****@*****.***

WORK EXPERIENCE:

Worked in Apollo Hospitals, Jubilee Hills, Hyderabad as Junior Molecular Technologist in Molecular Biology and Cytogenetics lab from July 2010 to March 2012

EDUCATIONAL QUALIFICATIONS

Master of Science in Bio medical Genetics (2007-2009) VIT University, Vellore.

7.18 CGPA.

PROJECT WORK (DECEMBER-MAY2009)

Project completed at human genetics lab of Centre for Cellular and Molecular Biology (CCMB), under the guidance of Dr.K.Thangaraj. The main research theme is to discover the “Genetic Study on Aruntharthiar Caste Population of Tamil Nadu using Mitochondrial and Y-Chromosome DNA markers”

Bachelor of Science (B.Sc) in Bio-technology (2004-2007) Vysya College, Salem

65.6 Percentage first class.

Higher secondary in Physics, Chemistry, Biology (2002-2004) T.E.S Higher secondary school 68.6 percentage, first class

10th in Trinity Matriculation school.75.2 percentage (2000-2002). First class

Publications:

Dayakar S, Iravathy Goud K.Rachana T, Tanuj S, Venkatesh R, Bharathi E, Munpally S. Chikungunya and Dengue virus co infection in south Indian population: A brief Report. Indian Journal of virology (In communication).

HANDS ON EXPERIENCE

DNA and RNA based qualitative and quantitative detection of infectious diseases:

Qualitative and Quantative Real Time PCR

Chikungunya virus

Dengue virus

EGFR gene Mutation analysis

Human immunodeficiency virus (HIV)

Hepatitis C virus detection and genotyping

Hepatitis B virus detection

Human Cytomegalovirus

Herpes simplex virus 1&2

Human papilloma virus & genotyping

Mycobacterium tuberculosis (meningitis)

PERSONAL DETAILS

Date of birth : 5th January 1985

Sex : Male

Nationality : Indian

Martial Status : Married

Languages Known : English, Telugu and Tamil

Permanent Address : 24A/13,Basheer Ahmed Layout,

Gandhi nagar,

Krishnagiri-635001.

Tamil Nadu.

REFERENCES

1.Dr.K.Thangaraj

Scientist EII

CCMB

Uppal Road

Hyderabad-500007

Mobile +91-990**-*****

Telephone +91-40-271****

Mail: ******@****.***.**

DETAILS OF PROJECT

PROJECT

Six months Project during December 2008 to May 2009 at CCMB, Hyderabad under the guidance of Dr.K.Thangaraj

TITLE

GENETIC STUDY ON ARUNTHATHIAR CASTE POPULATION OF TAMIL NADU USING MITOCHONDRIAL AND Y-CHROMOSOME DNA MARKERS.

AIM

To identify the genetic origin of 100 Blood samples of Arunthathiar caste population in Tamil Nadu using genetic markers

Abstract

The origin of the culturally and genetically diverse populations of India has been subject to numerous anthropological and genetic studies. It remains unsettled whether the genetic diversity seen between different Indian populations primarily reflects their local long-term differentiation or is due to relatively recent migrations from other country. Here, we made an attempt to understand the genetic composition, affinity and origin of Arunthathiyar, a caste population of Tamil Nadu. To trace the maternal ancestry we analyzed the hyper variable regions (HVR-I and HVR-2) of the mitochondrial DNA along with a few coding regions 12F, 15F, 18F and 22F of 93 individuals. We also analyzed 12 Y chromosome biallelic markers of the same set of samples to trace their paternal ancestry.

Based on the mutations observed in the hyper variable regions (HVR-I and HVR-2), and the selected coding regions of mtDNA, haplogroups were assigned. It was observed that all the individuals of the Arunthathiyar caste population were falling in both the macro haplogroups M (77%) and N (23%). Further, sub-haplogrouping of ‘M’ revealed that the samples were falling in haplogroups M2, M3, M4, M5, M6, M18, M30 and M35. Sub haplogrouping of macro- haplogroup N revealed the presence of J, R, R5, R7, U1 and U5.

Y chromosomal phylogeny, revealed Arunthathiyar population fall into haplogroups M82-H1, M69-H*, M172-J2, M9-K*, M11-L, M175-O, M45-PQ, M124-R2 and M17-R1a .

The mtDNA and the Y chromosomal analysis results indicate the presence of Indian specific gene pool in Arunthathiyar the caste population. The unimodal mismatch distribution curve indicates that the population had been expanding and now has become bottleneck.

Declaration:

I here by declare that all the above-mentioned information is true and correct to the best of my knowledge. I also assure that I’ll perform well if I were given an opportunity.

Thanking you

R. Venkatesh Babu

Place: Krishnagiri.

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