Chemist
Resume:
Curriculum Vitae
Nageswara Kode
Marrero, LA 70072.
504-***-****, cell 504-***-****
E-mail: ********@***.*** U S Citizen
Objective: Seeking a full time research, management or manufacuturing position.
Skills:
15+ years of experience on the design and synthesis of heterocyclic compounds, nucleosides, steroids and natural products of anti-cancer and anti-microbial interest.
Chromatographic separations of complex synthetic and natural products.
Applications of high field proton and carbon-13 NMR (500 MHz), Mass Spectrometry and other spectroscopic techniques for structure elucidation.
Process development and scale-up synthesis of active lead compounds. Applications of HPLC, GC, GCMS, UV, IR for organic and or analytical projects.
Worked as a manufacturing chemist for the production of several pharmaceutical bulk drugs and intermediates under GMP and GLP environment. Experienced in using pilot plant equipment and production equipment like glass lined reactors of 1000-1500 liters capacity.
Positions and Employment:
August 2012 to present. Independent chemical consultant and drug designer.
New Orleans, LA.
Designed 200 plus novel organic molecules of interest in drug discovery. Special emphasis was on the areas like neglected tropical diseases, anti-bacterial, anti-fungal, anti-cancer and in Alzheimer’s.
August 2003 to July 2012. Research Associate
College of Pharmacy, Xavier University of Louisiana,
New Orleans, LA 70125.
Research in Medicinal Chemistry. Design and Synthesis of novel nitrogen and oxygen heterocyclic compounds of anti-microbial interest. Synthesis of complex amidines, amidoximes and corresponding 1,2,4-Oxadiazoles. Synthesis of substituted Purines, Pyrimidines and Palladium catalyzed Suzuki cross coupling reactions. Chromatography, crystallizations, high field proton & carbon-13 NMR and mass spectrometry.
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Education:
Ph.D. Organic Chemistry, Osmania University, Hyderabad 500007, India.
All degrees have been evaluated in US by IERF at Culver city, CA and certified to be on par with US standards.
M.Sc. Organic Chemistry, University of Jabalpur, India.
B.Sc. Chemistry, Andhra University, India.
Selected publications out of 20:
* Design and Synthesis of N1,N5-bis[4-(5-Alkyl-1,2,4-oxadiazol-3-
yl)phenyl]glutaramides as Potential Antifungal Prodrugs.
Nageswara Rao Kode, Jean J. Vanden Eynde, Annie Mayence, Guangdi Wang and
Tien L. Huang.
Molecules 2013, 18, 112**-*****.
* 3-(Adamantan-1-yl)-4-hydroxybenzyl Substituted Purines and Pyrimidines :
Synthesis and Cytotoxic Activity.
Nageswara Rao Kode, Dakshinamurthy Devangachinta and Shashikant Phadtare.
Letters in Drug Design & Discovery Vol. 9 (10) 926-933 (2012).
*Synthesis and cytotoxic activity of some new 2,6-Substituted Purines.
Nageswara Rao Kode and Shashikant Phadtare.
Molecules 2011, 16 (7), 5840-5860.
* Trypanocidal activity of piperazine-linked bisbenzamidines and bisbenzamidoxime, an orally active prodrug.
Tien L. Huang, Cyrus J. Bacchi, Nageswara.R. Kode, Qiang Zhang, Guangdi Wang, Nigel Yartletd, Donna Rattendi, Indira London, Lakshman Mazumder, Jean Jacques Vanden Eynde, Annie Mayence, Isaac O. Donkor
Antimicrobial Agents and Chemotherapy Vol. 30, 555-561(2007).
* Synthesis of novel flavonoid derivatives as potential HIV-integrase inhibitors.
Mateeva Nelly N, Kode N. Rao, Kinfe K. Redda.
Journal of Heterocyclic Chemistry, Vol. 39(6), 1251-1258 (2002).
* Synthesis of some N-[Pyridyl(Phenyl)carbonylamino]-Hydroxyalkyl(Benzyl)-1,2,3,6-tetrahydropyridines as Potential anti-inflammatory agents.
Kode Nageswara Rao, Kinfe K. Redda, Folakemi Y. Onayemi, Hailemichael Melles and J. Choi.
J. Heterocyclic Chemistry, Vol. 32, 307-315 (1995).
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* Synthesis and anti-inflammatory activities of some N-[Pyridyl(Phenyl)carbonylamino]-alkyl-1,2,3,6-tetrahydropyridines.
Kinfe K. Redda, Kode N.Rao, Ann S. Heiman, Folakemi Y. Onayemi and Janine B. Clark
Chemical & Pharmaceutical Bulletin, Vol. 39, (3), 786-791 (1991).
* Synthesis of some N-[Pyridyl (Phenyl) carbonylamino]-alkyl-1,2,3,6-tetrahydropyridines.
Kinfe K. Redda, Hailemicael Melles and Kode Nageswara Rao.
J. Heterocyclic Chemistry, Vol. 27, 104–1046 (1990).
References:
Dr. Tien Huang
College of Pharmacy, Xavier University of Louisiana
New Orleans, LA 70125
E-mail: ******@****.*** *Phone 504-***-****
Dr. Sahikant Phadtare
College of Pharmacy, Xavier University of Louisiana
New Orleans, LA 70125
E-mail: ********@*****.***
Dr. Vimal Kishore
College of Pharmacy, Xavier University of Louisiana
New Orleans, LA 70125
E-mail: ********@****.*** *Phone 504-***-****
Dr. Robert Blake
College of Pharmacy, Xavier University of Louisiana
New Orleans, LA 70125
E-mail: ******@****.*** *Phone 504-***-****
Contact this candidate