Christina Thomas
Houston, TX 77030
Email: ***********@*****.***
Ph: 213-***-****
PROFFESSIONAL EXPERIENCE
Project Intern: 22 Sept 2014 - Present (Part time)
Baylor College of Medicine, Dept of Neurology, Houston, TX 77030
Responsibilities: Coordinating the recruiting of research subjects for a
study involving specialized MRI scanning tests.
Research Assistant: 01 June 2011 - 14 Feb 2013
Thrombosis Research Unit, Biomedical Technology Wing, Sree Chitra Tirunal
Institute for Medical Sciences and Technology (SCTIMST), Thiruvanathapuram,
India. Responsibilities: Worked in Indian Council of Medical Research
(ICMR) funded Project to develop an injectable and implantable drug
delivery vehicle using human proteins as agent for immobilizing curcumin
and to attain sustained release which is the basis in cancer therapy.
Achievements:
1. Published Paper:
Thomas, C., Pillai, L.S. and Krishnan, L. (2014) Evaluation of Albuminated
Curcumin as Soluble Drug Form to Control Growth of Cancer Cells in Vitro.
Journal of Cancer Therapy, 5, 723-734.
2. Patent: Indian patent - No. 2200/CHE/2013.
PCT application number: PCT/IN2014/000338 - Filed on 20th May, 2014.
3. Second author research paper under process.
Research Associate: 08 Sept 2010 - 27 May 2011,
Science and Technology Promotion Division (STPD), Kerala State Council for
Science Technology and Environment (KSCSTE), Thiruvanthapuram, India
Program involved- Science research Scheme (SRS) and Scheme for promoting
young talents in Science (SPYTiS).
Responsibilities: Involved in the scientific management with administrative
responsibility of conducting various administrative procedures for
evaluating and recommending the project proposals submitted by various
researchers to KSCSTE for financial and technical assistance pertaining to
areas of Life sciences, Agriculture, Physical and Chemical Sciences, under
the SRS and SPYTiS Scheme.
Assistant Professor: 23Nov 2006 - 31Jan 2010
Department of Biotechnology, Rajiv Gandhi College, Madhya Pradesh, India
- Handled theory classes for undergraduate and postgraduate courses in
Biotechnology and Biochemistry. (Subjects dealt: Immunology, Biochemistry,
Enzymology, and Pharmaceutical Biotechnology).
- Handled Biochemical Practical classes and organized one-day workshop,
'Microbiological World', participated by multiple colleges, at the Rajiv
Gandhi College. -- Led a one-day demonstration on Enzyme Immobilization and
ELISA by students of Rajiv Gandhi College.
ACADEMIC QUALIFICATIONS
2004 BS Chemistry - with subsidiary Mathematics and Physics, Mahatma
Gandhi University, India. GPA: 3.78.
2006 MS Biochemistry, Bharathiar University, India. GPA: 3.85.
- Dissertation Title: Kinetic Parameters of Glutamate Dehydrogenases
Activity in the Cerebellum of Adrenalectomized and Hydrocortisone treated
Mice, Center of Neurosciences, Cochin University of Science and
Technology, India. Description/Objective: Measurement of the activity of
Glutamate Dehydrogenase in Adernalectomized and Hydrocortisone treated
mice, to determine the significance of Hydrocortisone in treating
adrenalectomized mice.
AWARDS
Proficiency Certificate in Biochemistry from Karpagam Arts and Science
College, Coimbatore, India
TRAINING AND SEMINARS
- Underwent 30-day training at C.M.C Hospital, Kottayam, Kerala, India
where I got a thorough exposure to various diagnostic tests.
- Participated in National Conference on 'Technological Advancements in
Clinical Biochemistry' - organized by Karpagam Arts & Science College
(2005)
- Attended State-level Seminar on 'Recent Trends in Biochemistry'-
organized by Dr. N.G.P. Arts and Science College, Coimbatore (2005).
PROFESSIONAL AFFILIATIONS
Life Member, Society of Biotechnologists (India). Regd No.ER57\95.
SKILL SET:
. Isolating primary cells (Human Vein Endothelial Cells, HUVEC),
maintaining and handling of primary cells (Human Fibroblast Cells, Sheep
Fibroblast Cells).
. Handling and maintaining cancer cell lines (Lung, Breast, Glioma,
Prostate, Leukemia, Lymphoma cell lines for study).
. Cryopreservation.
. Apoptosis assay using flow cytometry (Aria, BD and Beckmann coulter).
. Cell cycle arrest using flow cytometry.
. Knowledge of FlowJo software,BD FACS Diva, Leica &Agilent Chem
Station.
. Chromatography
. Gel permeation chromatography - preparation and packing of the column
with Sephadex beads.
. Ion exchange chromatography.
. Paper chromatography - ascending, descending and radial
chromatography, development of chromatogram.
. Thin layer chromatography.
Others:
. Spectrophotometer.
. Protein purification using dialysis.
. Qualitative and quantitative analysis of carbohydrate, proteins and
amino acids.
. Staining techniques.
. Basic microbiology techniques.
. Maintenance of Animal Tissue Culture labs.
. DNA isolation from plants. Immunological assays - single diffusion and
double diffusion.
. Immunological assays - single diffusion and double diffusion.
. Enzyme assay and immobilization in alginate beads.
. Western blotting, Silver staining,PCR
. Handling of various equipments such as ELISA reader, PCR,refrigerated
centrifuge,bioreactor, pH meter, lyophiliser, steam sterilizer,
laminar flow, CO2 incubator, Incubator shaker, shaking water bath, hot
air oven, Bright field and inverted phase contrast microscopes, flow
cytometer, incubator.
. Familiarity with Gravimetric analysis.
AREAS OF RESEARCH INTEREST:
. Cancer Biology and Therapeutics
. Drug targeting
. Immunology
REFRENCES:
1. Dr.Zulfi Haneef, MD, FRCP (UK)
Assistant Professor in Neurology,
Peter Kellaway Section of Neurophysiology
Department of Neurology, Baylor College of Medicine,
One Baylor Plaza, MS: NB302
Houston, TX 77030
Email: *****.******@***.***
2. Dr. Lissy Kalyana Krishnan
Scientist G and Leader
Thrombosis Research Unit
Thrombosis Research Unit
Sree chitra Tirunal Institute for medical sciences and
technology
Poojapura
Thiruvanathapuram, Kerala, India
Email: *******@*******.**.**
3. Dr. R Prakash Kumar
Scientist F and Head
Science and Technology Promotion Division
KSCSTE, Thiruvanthapuram, India
Email: *******@*****.***