Maintenance Project

SAMATHA VADREVU

**** **** ****** **, ****** CA 95630

**************@*****.***

575-***-****

Summary:

A motivated Research and Development (R&D) Associate passionately committed towards the

discovery and development of novel therapeutic compounds at a preclinical stage. A strong and

proactive team player, proficient in handling multiple projects effectively. Collaborated with project

team leads, Scientists, Directors, Post docs and senior level executives across multidisciplinary teams

in an organizational and academic setup.

Skills:

Experience in assay development for multidrug resistant bacteria (MDR), at a preclinical level in

invitro and invivo setups in a GMP certified lab and GLP environment. Skilled in performing

molecular biology techniques. Technical knowledge of subjects includes Microbiology, Genetics,

Immunology, Virology, and Biochemistry.

Work Experience:

UC Davis (Department of Microbiology and Molecular Genetics)

Research Intern Mar’14 – July’14

• Working on Breast and ovarian cancer tumor Suppressor protein (BRCA2)

• Performed molecular biology techniques including genomic DNA/plasmid

preparation, PCR, DNA gel electrophoresis, restriction digestion, ligation, transformation and

molecular cloning, SDS- PAGE, Western blot analysis.

• Experienced in growing large cultures.

• Experienced in Operating standard laboratory equipment’s.

Aurigene Discovery Technologies (Subsidiary of Dr. Reddy’s Foundation) Hyderabad, India

Research Associate Oct’10-Apr’12

• Experience in working on various in vivo and in vitro protocols using standard

antibiotics and NCE’s (New Chemical Entity) against various pathogenic bacterial strains like

Streptococcus, Pseudomonas, Klebsiella and other multi drug resistant bacteria in a GMP certified

BSL-II facility.

• Conducted MIC (Minimum Inhibitory Concentration) using Molar Solutions for

collaborator projects with Merck and Pcovery. Documented the protocols in lab notebooks.

• Prepared Laboratory notebooks, technical reports, summaries, protocols.

• Participated in lab organizational meetings.

Invitro

• Performed MIC, MBC (Minimum Bactericidal Concentration) using standard antibiotics.

• Performed Agar MIC method using various bacterial strains.

• Trained in assays like TKK (Time Kill Kinetics), PAE & PASME (Post Antibiotic Effect

& Post Antibiotic Sub MIC Effect) using standard antibiotics.

• Performed DDA (Disc Diffusion Assays) and Agar Dilution Assays using standard

antibiotics against different bacterial strains.

• Experienced in maintenance of viable bacterial culture (Cryovial Preservation).

• Performed MPC (Mutant Prevention Concentration) with standard antibiotics against

bacterial strains. Staining procedures for identification of Bacterial Morphology

• Performed various biochemical tests for Identification and Classification of bacteria.

Invivo

• Familiar with animal handling (Mice).

• Performed LD50 (Lethal Dose) & ED50 (Effective dose) studies on mice with bacterial and

fungal strains against standard antibiotics.

• Passaged Strain maintenance (bacterial and fungal strains).

• Biogene Biotechnologies, India Jan’10-

Mar’10

Research Intern:

• Trained in the techniques that separate biological macromolecules like proteins and

nucleic acids.

Institute of Preventive Medicine Mar’08 – May’08

Intern:

• Analyzed water samples in Microbiological and Chemical procedures at IPM

(Institute of Preventive Medicine). This institute specializes in vaccine treatment.

Education:

University of California Davis, CA Sept’13- June ‘14

Pursuing Business Certificate in Innovation and Sustainability

• Actively participated in field trips to learn about an organization’s triple bottom line

of people, planet and environment

• Thorough knowledge of metrics like green chemistry and bioremediation used for

achieving sustainability practices in pharmaceutical industry.

Osmania University, India Jun‘08 -Jul’10

MSc (Master of Science) Microbiology

Osmania University, India Jun’05 -Mar’ 08

BSc (Bachelor of Science) Microbiology, Genetics and Chemistry

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• Other Activities:

• Participated in activities like Model Mania, Inter College Competitions and Science fairs.

Been a member of Rotary International Club and was engaged in social activities.

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• Visa Status:

• Currently on a full time student (F1) visa.

• Will obtain an OPT this summer which will let me work in the US without any

sponsorship restrictions.

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