Project University

VINITA YADAV

***, ********** ** *********, *** Pennsylvania State University, University Park

630-***-****; ******@***.***

• 6+ years of combined research experience in industry and academia

HIGHLIGHTS

• Interdisciplinary research skills in colloids, chemical & material characterization, and pharmaceutics

• Research on colloidal delivery agents widely acclaimed in scientific magazines and forums (>25

independent reports)

• Authored 6 publications, 2 invited reviews, 1 book chapter and 4+ conference presentations

• Expertise in colloidal synthesis, analytical techniques, time management, data analysis and

presentation

Ph.D. candidate, Chemistry (GPA 3.88/4.0)

EDUCATION

Pennsylvania State University, State College, PA (Aug. 2011- present)

M.S., Chemistry (First Class)

University of Delhi, Delhi, India (2004 - 2006)

B.S., in Chemistry (major), (First class with honors)

University of Delhi, Delhi, India (2001 - 2004)

• Adept in colloidal science, materials chemistry, and low Reynolds number hydrodynamics

LABORATORY & TECHNICAL SKILLS

• Skilled in working in a clean room and biosafety level II, GLP compliant environment

• Microscopy: Electron Microscopy: Field emission (FESEM) & Environmental (ESEM), Confocal

fluorescence microscopy, Optical microscopy

• Lithography: Soft lithography, Photolithography (Contact, Laser), Wet Chemical etching

• Chromatography: High Performance Liquid Chromatography (HPLC), Gas Chromatography (GC)

• Spectroscopy: Raman, UV/Visible, NMR, Fourier Transform Infrared (FTIR): Micro, Transmission, ATR

• Other Analytical Techniques: Wet chemistry, Elemental analysis, PXRD, ZP, DLS, XRF, AFM

• Micro-biology: Bacteria culture, Bacteria staining, Cryotome, Protein tagging and purification

• Pharmaceutics: Drug assays, Impurity profiling, Heavy metal analysis, Dissolution tester, Polarimetry

RESEARCH EXPERIENCE

1. ACADEMIC

Ph.D candidate, advised by Prof. Ayusman Sen

The Pennsylvania State University (Penn-state), University Park, PA (2011-present)

Project #1: Colloidal Delivery Agents to Repair Damaged Human Tissues

• Developed a unique targeting technique for bone and teeth micro-cracks that enables damage detection

and repair, fully tested in biomimetic in-vitro environment; being followed up by in-vivo studies

• Designed biocompatible colloids and suspensions using FDA approved materials and methods to transport

bone morphogenetic proteins, growth factors and cell generating drugs to the crack site

Project #2: Crack Repair – Biomaterials to Polymers

• Conceptualized a polymer-crack repair system using emulsified colloidal repair agents

• Synthesized emulsions, pre-loaded with repair agents, and characterized them with analytical techniques

like SEM, Zeta potential, Raman spectroscopy and DLS

Project #3: Versatile Scavenging Colloidal Pump

• Intellectualized a chemically modified smart polymeric material that pumps colloidal systems while

exhibiting memory for pre-defined stimuli (ion or photo-triggered)

• Encoded smart polymeric material to selectively scavenge biological and inorganic colloidal species based

on charge

1

Project #4: Characterizing Protein/Enzyme Mobility using Micro-fluidics

• Utilizing contact photolithography, fabricated soft lithography based microfluidic devices aimed at

analyzing protein interactions with substrate and inhibitor

• Formulated micro-emulsions containing proteins, fluorescent labelling of proteins and enzymes and their

purification, diffusion studies in hydrogels

Project #5: Development of Switchable Colloidal Transport Systems

• Developed stimuli responsive, self-powered colloidal micro-pumps that contain multiple levels of

regulation over colloidal motion

• Engineered control into colloidal micro-fluidic pumps by fabricating a novel photo-triggered “on/off”

switch capable of generating nano-scale patterns and channel-less flows

2. INDUSTRIAL

Jubilant Life Sciences, Noida, India (2010 – 2011)

• Investigated Active Pharmaceutical Ingredient (API) of potential drug molecules and finished drug

Research associate, Analytical Department, Research and Formulation Division

products for their assays, performed stability studies, impurity separation and identification using

chromatographic techniques; Studied drug release profiles using dissolution tester

• Performed wet chemical analysis on formulations in accordance with market specific pharmacopeia

• Experience in analytical development at R&D facility and technology transfer at manufacturing plant

• Proficient in documentation: writing SOPs, quality compliance and audit reports

Invited speaker, Gordon Research Conference, 2014

HONORS AND AWARDS

• Special honor given to discuss research ideas

Very Important Paper, Angewante Chemie, 2013

• Special recognition given to research on drug delivery

Noteworthy Paper, Angewante Chemie, 2013

• Special recognition given to research on colloidal pumps

Selected for Future Faculty Workshop at Georgia Tech., NSF, Summer 2013

• Sponsored by NSF for 35 students nationwide

Travel Award, The Pennsylvania State University, Fall 2012, Spring 2014

• Financial award given to support travel to the ACS National Meeting, Gordon Conference

Graduate Fellowship, The Pennsylvania State University, 2011-2012

• Financial award given for academic excellence

Merit Award, University of Delhi, 2006

• Given to top 10% students during M.S

Gold Medalist, University of Delhi, 2004

• Given for best overall performance during B.S.

Merit Award, University of Delhi, 2004

• Given for achieving first position in final year of B.S.

1. Yadav, V.; Zhang, H.; Pavlick, R.; Sen, A. Triggered “on/off” Microfluidic Pumps and Colloidal Photo-Diode, J.

PUBLICATIONS

Am. Chem. Soc., 2012, 134, 15688–15691

2. Yadav, V.; Freedman, J.; Grinstaff. M.; Sen, A. Bone-Crack detection, targeting and repair using ion gradients,

Angew. Chem. Int. Ed., 2013, 52, 10997–11001 (Accepted as ‘Very Important Paper’; Article featured in

Centre Daily Times, Chemistry World, PHYSORG, NSF, among others.)

3. Baker, M. S.; Yadav, V.; Sen, A.; Phillips, S. T. Self-Powered Polymeric Functional Materials that Respond

Autonomously and Continuously to Fleeting Stimuli, Angew. Chem. Int. Ed., 2013, 52, 10295–10299

2

(Selected as ‘Noteworthy Paper’; Article highlighted in

Innovation forum.)

Nature Chemistry, PHYSORG, Chem Views,

4. Yadav, V.; Duan, W.; Sen, A. Diffusiophoretic Nano and Microscale Propulsion and Communication, invited

book chapter, Engineering of chemical complexity, 2014 Ed.

5. Yadav, V.; Pavlick, R. A.; Meckler, S.; Sen. A. Salt Triggered Detection and Polymer Deposition: Towards the

Repair of Microcracks, ACS Nano, submitted, 2014

6. Duan, W.; Wang, W.; Yadav, V.; Sen, A. Propulsion at Micro and Nano-scale: Sensing, Capture, Delivery and

Separation, Annual Review of Analytical Chemistry, invited review, 2014

7. Yadav, V.; Freedman, J.; Grinstaff. M.; Sen, A. Repairing mineralized biomaterials in-vitro to in-vivo

manuscript in preparation for Nature Nanotechnology, 2014

8. Yadav, V.; Zhao, X.; Sen, A. Enzyme phobotaxis, manuscript in preparation for Nature Chemistry, 2014

9. Yadav, V.; Sen, A. Anatomy of Nanomotors, Annual Review of Biophysics, invited review, 2014

1. Yadav, V.; Sen, A. “Active Bone-Crack detection, targeting and repair using ion gradients”. Invited Speaker,

SELECTED CONFERENCE PRESENTATIONS

Gordon Research Seminar, Ventura, CA (February 2014)

2. Yadav, V.; Sen, A. “Self-propelling Bio-Hybrid Micro-pumps”, Poster, Gordon Research Conference, Ventura,

CA (February 2014)

3. Yadav, V.; Sen, A. “Crack detection, targeting and repair using ion gradients”, Poster, Materials Day, The

Pennsylvania State University, PA (October, 2013)

4. Yadav, V.; Sen, A. “Triggered “on/off” Microfluidic Pumps and Colloidal Photo-Diode”, Poster, 244th ACS

National Meeting, Philadelphia, PA (August, 2012)

• Grinstaff Group, Biomedical Engineering, Boston University (2012-present)

RESEARCH COLLABORATIONS

• Phillips Group, Chemistry, The Pennsylvania State University (2012-2013)

Teaching Assistant, The Pennsylvania State University (2011-2012)

POSITIONS OF RESPONSIBILITY

Mentor: Undergraduate REU students (2012-2013)

•

Education Outreach: Designed and performed science demonstration for schools (2012, 2013)

•

Supervisor: Confocal microscope, Optical microscope (2012-present)

•

Enforcing safety practices in the lab (2012-present)

•

Wet lab Supervisor at Jubilant Life Sciences (2011)

•

Chemistry Society, Executive council member (2003 - 04)

•

College Magazine, Member of the editorial team (2002 - 03)

•

College Magazine, Coordinator (2001 - 02)

•

•

• Member, Graduate Women in Science

PROFESSIONAL AFFILIATIONS

• Member, American Chemical Society

• Member, MRSEC at Pennsylvania State University

3

Contact this candidate