XIAXIA (Shia Shia) YU
Email: ********.**@*****.*** Phone: 404-***-****
Homepage: https://sites.google.com/site/xiaxiayushomepage
SUMMARY
A self motivated Ph. D experienced in developing new classification algorithms and predictive
model on large scale data, analyzing and retrieving information from high dimensional data,
programming, data analysis, and machine learning algorithms. Extensive and strong skills in:
Statistical data analysis using regression techniques
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Implementation of machine learning algorithms, including Sparse Representation,
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Regressions, Neural Networks, and Support Vector Machine
Application of machine learning algorithms to classification in large scale data
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EDUCATION
Georgia State University, Atlanta, GA
05/2014
Ph.D Computer Science
Georgia State University, Atlanta, GA
12/2009
M.S. Bioinformatics and Structural Biology
Wuhan University, Wuhan, China
07/2007
B.S. Biological Science (major), Computer Science (minor)
TECHNICAL SKILLS
Programming/Scripting: Python, Java, Matlab, R
Database and web development: MySQL, PHP, HTML, JavaScript
Operating System: Windows and Linux/Unix
PROFESSIONAL EXPERIENCE
Georgia State University, Department of Computer Science, Atlanta, GA
2010 Present
Research Assistant
Dissertation: HIV Drug Resistant Prediction and Featured Mutants Selection Using Machine
Learning Approaches
Developed and implemented a new protein encoding algorithm
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Performed the multiple regression to predict the HIV 1 drug resistance values
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Designed a new classification algorithm to predict the drug resistance
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Evaluated the new algorithm by comparing its performance with SVM and ANN
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Compared the performance of the new algorithm with other Genotypic resistance
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interpretation systems
Retrieved essential featured HIV 1 drug resistant mutants targeted to different drugs
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XIAXIA (Shia Shia) YU
Email: ********.**@*****.*** Phone: 404-***-****
Homepage: https://sites.google.com/site/xiaxiayushomepage
Web design project
Designed a website for users to search, book and rate movies using PHP, HTML, JavaScript
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and tomcat
Managed the database with all the movies and their ratings using MySQL
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Implemented features of user rating system with database queries and scheme design.
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Software development project
Team work with group of five members
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Developed a portable, system independent text editor
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Implemented a user interface and file Input/Output function of the editor
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Implemented text editing features in addition to word count, formatting, and searching
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Georgia State University, Department of Computer Science, Atlanta, GA
2010 Present
Graduate Teaching Assistant
Instructed undergraduate courses and graded assignments and exams
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Communicated with the professors about the students’ study progress
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Course instructor, Introduction to Computer Programming
Fall 2011
Taught more than 20 undergraduate students on Python programming
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PUBLICATIONS
Peer to peer Conference Papers
Xiaxia Yu, Irene T. Weber, and Robert W. Harrison. Sparse representation for hiv 1
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protease drug resistance prediction. in Data Mining (SDM), 2013 SIAM International Conference
on. SIAM, 2013, pp. 342 349.
Xiaxia Yu, Irene T. Weber, and Robert W. Harrison. HIV drug resistance prediction using
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multiple regression, an application of a new sequence/structure hybrid protein encoding method. in
Computational Advances in Bio and Medical Sciences (ICCABS), 3rd IEEE International
Conference on. IEEE, 2013, pp. 1 2.
Robert W. Harrison, Xiaxia Yu, and Irene T. Weber. Using triangulation to include target
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structure improves drug resistance prediction accuracy. in Computational Advances in Bio and
Medical Sciences (ICCABS), 3rd IEEE International Conference on. IEEE, 2013, pp. 1.
Promita Bose, Xiaxia Yu, and Robert W Harrison. Encoding protein structure with
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functions on graphs. in Bioinformatics and Biomedicine Workshops (BIBMW), 2011 IEEE
International Conference on. IEEE, 2011, pp. 338 344.
Journal Papers
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XIAXIA (Shia Shia) YU
Email: ********.**@*****.*** Phone: 404-***-****
Homepage: https://sites.google.com/site/xiaxiayushomepage
Xiaxia Yu, Irene T. Weber, and Robert W. Harrison. Prediction of HIV drug resistance
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from genotype with encoded three dimensional protein structure. BMC genomics, 2014. (Minor
revision).
Chen Hsiang Shen, Yunfeng Tie, Xiaxia Yu, Yuan Fang Wang, Andrey Y Kovalevsky,
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Robert W Harrison, and Irene T Weber. Capturing the reaction pathway in near atomic resolution
crystal structures of hiv 1 protease. Biochemistry, vol. 51, no. 39, pp. 7726 7732, 2012.
Yu Chung E Chang, Xiaxia Yu, Ying Zhang, Yunfeng Tie, Yuan Fang Wang, Sofiya
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Yashchuk, Arun K Ghosh, Robert W Harrison, and Irene T Weber. Potent antiviral hiv 1 protease
inhibitor grl 02031 adapts to the structures of drug resistant mutants with its p1 pyrrolidinone ring .
Journal of medicinal chemistry, vol. 55, no. 7, pp. 3387 3397, 2012.
Ying He, Jinzhen Shao, Xiaxia Yu, Qianhe Wang, Bohua Zhu, and Yi Ding. Study on
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storage protein of high quality hybrid rice in hubei province. Journal of WUHAN Botanical
Research, vol. 25, no. 3, pp.270 276, 2007. (In Chinese)
Kan Hu, Xiaxia Yu, Jinhong Yu, and Yi Ding. Construction of an analysis between three
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lines of cytoplasmic non pollen type in yunnan purple rice and their hybrid f1. Chinese Journal of
Rice Science, vol. 21, no. 4, pp. 345 349, 2007. (In Chinese)
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